The incidence of spinal treatment, including nerve block, radiofrequency neurotomy, instrumented fusions, is increasing, and progressively involves patients of age 65 and older. Treatment of the geriatric patients is often a difficult challenge for the spine surgeon. General health, sociofamilial and mental condition of the patients as well as the treatment techniques and postoperative management are to be accurately evaluated and planned. We tried to compare three treatment methods of spinal stenosis for geriatric patient in single institution.
The cases of treatment methods in spinal stenosis over than 65 years old were analyzed. The numbers of patients were 371 underwent nerve block, radiofrequency neurotomy, instrumented fusions from January 2009 to December 2012 (nerve block: 253, radiofrequency neurotomy: 56, instrumented fusions: 62). The authors reviewed medical records, operative findings and postoperative clinical results, retrospectively. Simple X-ray were evaluated and clinical outcome was measured by Odom's criteria at 1 month after procedures.
We were observed excellent and good results in 162 (64%) patients with nerve block, 40 (71%) patient with radIofrequency neurotomy, 46 (74%) patient with spinal surgery. Poor results were 20 (8%) patients in nerve block, 2 (3%) patients in radiofrequency neurotomy, 3 (5%) patient in spinal surgery.
We reviewed literatures and analyzed three treatment methods of spinal stenosis for geriatric patients. Although the long term outcome of surgical treatment was most favorable, radiofrequency neurotomy and nerve block can be considered for the secondary management of elderly lumbar spinals stenosis patients.
As development of medical techniques provided the extension of human life, the number of elderly has been increasing. For this reason, prevalence rate of geriatric illness is also increase with growth of needs of geriatric patients. Among numerous geriatric diseases, low back pain occupied a large proportions and their will for treatment has been changing from conservative medical treatment to aggressive surgical treatment. Because many factors were involved in low back pain, it is hard to make a appropriate decision for treatment of low back pain in old patinets.
Among many factors causing low back pain, degenerative lumbar spinal stenosis is a major cause of pain in people over the age of 65 years
In present study, we analyzed and compared clinical outcome and efficacy of treatment to elderly patients who underwent nerve block, radiofrequency neurotomy and surgery for spinal stenosis in our hospital.
Case of 371 patients who over the age of 65 years and underwent nerve block, radiofrequency neurotomy or surgery for spinal stenosis at our center between January 2009 and December 2012 were retrospectively analyzed. We reviewed medical and surgical record, radiological study such as magnetic resonance image.
Most patients underwent MR imaging of the lumbar spine at our clinic or others, and the extent of spinal stenosis could be estimated. Compression of the lumbar dural sac was clearly delineated. We also routinely performed plain anteroposterior and lateral radiography of the lumbar spine to exclude developmental disorders. Additionally, we divided to spinal stenosis severity as defined by Schonstrom
Before treatment, the patient received medical therapy to manage their pain, minimally consisting of physical therapy and the use of NSAIDs if not contraindicated. In case of insufficient pain relief, patients were judged eligible for nerve block treatment.
Among the patients received nerve block, when nerve block performed if there is a 50% reduction in symptoms after the intervention, the patients were judged suitable for radiofrequency neurotomy.
We performed the surgery when the following criteria were met: there were clear symptoms of neural claudication with corresponding signs of a radiological correlate, 3 months of conservative treatment, which included nerve block and radiofrequency neurotomy, did not improve the patient's symptoms. We selected patients who underwent only posterolateral interbody fusion except other surgery for direct comparison of clinical outcome.
All injection procedures were performed under fluoroscopic guidance while the patient was lying in prone position. Also injection were performed using established techniques using lidocaine(0.5%) and methylprednisolone.
A radiofrequency neurotomy was only considered after positive testing (at leat 50% pain relief). Procedures were performed with fluoroscopic visualization. The level of spinal stenosis was always included in the radiofrequency neurotomy. In nearly all patients, one or 2 adjacent levels were also included. For radiofrequency neurotomy a NeuroTherm NT 1,000 generator was used. The cannulae used were 150mm length, 20-gauge with a 10mm active tip. The total time of the lesion at 42℃ was 120 seconds for each cycle at each level. At each level, the needle was placed parallel to the nerve; multiple lesions were made in parallel for each medial branch. Lidocaine was used as a local anaesthetic. Sometimes, nerve stimulation was performed prior to radiofrequency lesioning.
Almost patients received posterolateral interboby fusion and posterior screw fixation. Surgery was performed using established techniques in one level which include spinal stenosis lesion.
Clinical outcome was determined according to scoring and changes on the visual analogue scale (VAS) for pain and Odom's criteria at the time of pre-procedures and at 1 month after procedures. Additionally, the changes of lumbar spine were assessed with a lumbar spine plain radiography.
Among 371 patients who over the age of 65 years and underwent treatments for spinal stenosis at our center between January 2009 and December 2012, nerve block was performed in 253 patients, radiofrequency neurotomy was performed in 56 patients and surgery was performed in 62 patients. These represent about 68.2%, 15.1%, 16.7% of all patient undergoing treatment for spinal stenosis, respectively. The mean age of the patients who underwent nerve block was 70.6±4.5 years (mean±SD, range: 65-87), among whom 80 were males and 173 were females. The mean age of the patients who underwent radiofrequency neurotomy was 72.2±1.9 years (mean±SD, range: 65-75), among whom 19 were males and 37 were females. The mean age of the patients who underwent surgery was 69.4±6.0 years (mean±SD, range: 65-80), among whom 28 were males and 34 were females (
These are summarized in
Among 253 patients, 114 patients did complain of a low back pain, 113 patients did complain of a radiculopathy and the remaining 26 patients did complain of a neurogenic claudiacation.
Among 56 patients, 41 patients did complain of a radiculopathy, 12 patients did complain of a low back pain and the remaining 3 patients did complain of a neurogenic claudiacation.
Among 62 patients, 32 patients did complain of a radiculopathy, 16 patients did complain of a neurogenic claudication and the remaining 14 patients did complain of a low back pain.
In cases of nerve block, the mean score of pre-nerve block was 6.9±1.2, and then the mean score was 3.7±1.4 at l month after procedure. In cases of radiofrequency neurotomy, the mean score of pre-radiofrequency neurotomy was 7.4±0.6, and then the mean score was 3.4±0.8 at 1 month later. In cases of surgery, the mean score of pre-surgery was 7.5±0.5, the mean score of a month after post-surgery was 3.4±0.4 (
At 1 month after treatment, review of the post-treatment of patient who underwent nerve block revealed 163 patients (64%) with excellent or good and 20 patients (8%) with poor grade. In cases of radiofrequency neurotomy, 40 patients (71%) represented excellent or good and 2 patients (3%) represented poor. Out of 62 patients who underwent surgery, 46 patients (74%) expressed excellent or good and 3 patients (5%) expressed poor (
Among the nerve block group, 101 patients received retreatment because insufficient pain relief and complication of infection occurred in 1 patient. In cases of radiofrequency neurotomy, 3 patients received retreatment and there were no complications. Among surgical group, 2 patients received revision surgery and 2 cases of complications occurred it was post-operative infections.
Spinal stenosis is a degenerative condition that affects the lumbar spine. This can be an incidental finding, but can cause back and leg symptoms, or neurogenic claudication
Surgery for spinal stenosis has been on the increase. Some good outcomes from surgical interventions have been demonstrated, but outcomes vary widely, and complications and re-operations have been reported
The scientifically valid studies that have been performed in this area to date are few, and none of them had a clear age limit or age restriction. Direct comparisons of conservative and surgical treatment are further complicated by the fact that patients with mild stenosis generally undergo the former, while those with severe stenosis generally undergo the latter. Chou et al., in a review of this topic, concluded that moderately good evidence indicates the superiority of surgical over conservative treatment in the first two years. The available evidence is hard to assess, however, because the six randomized trials whose findings were presented involved different surgical methods and variable follow-up intervals
Atlas et al. prospectively followed patients for eight to ten years and found better results in the first four years in the patients who had undergone surgery. At the end of the follow-up period, however, the two groups no longer differed with respect to low back pain or overall satisfaction, while all patients had a marked reduction of the leg-pain component. It must be noted, however, that 37% of the patients who were initially treated conservatively went on to have surgery. Radicular symptoms were improved in 67% of the patients who had surgery and in 41% of those treated conservatively
Lumbar spinal stenosis is being treated surgically with more frequency. However, clinical experience indicates that many patients also do well on a regimen conservative treatment only. And it can be performed more frequently in elderly patients.
In 2011, Boxem et al. reported that among the patient who underwent radiofrequency neurotomy for spinal stenosis, 22.9% presented 50% pain relief after 6 months and after 12 months in 13.1% of the cases
The complication rate after surgical treatment of spinal stenosis is considerable. In a prospective study published in 2010, 101 patients over the age of 70 who underwent surgery had an 18% complication rate. The most common complication was a dural injury without further clinical consequences (9%). Two patients had deep wound infections, and three died of concomitant, unrelated illnesses 26 days, 9 months, and 11 months after surgery
The pain relief from the radiofrequency neurotomy is sufficient to allow many of the patients to improve their activity tolerance and reduce other therapies for pain
A limitations of our study; first, it was selection of patient groups. We studied to only mild to moderate stenosis patients, excluding severe stenosis patient who need to surgical treatment. Also, in our study, we performed nerve block or radiofrequency neurotomy to patients who do not need to surgery. Therefore, our results were barely suitable for comparison to surgical outcomes. Second, we did not long term follow up. Slatis et al. reported that, based on data concerning functional ability and perceived back and leg pain, surgical treatment of lumbar spinal stenosis provided better results than conservative methods of treatment at the 6-year follow up
According to the above mentioned, long term outcomes of surgical treatment were better than conservative manage such as nerve block and radiofrequency neurotomy. However, we suggest that radiofrequency neurotomy may consider the effective secondary treatment to elderly patient that unable or refuse to surgery for lumbar spinal stenosis.
Recently, many of therapies were development and performed for symptomatic spinal stenosis because the symptoms related to quality of life in elderly patients. In our study, as a result of effectiveness of treatment for spinal stenosis, we found that radiofrequency neurotomy and nerve block were effective treatment. Although the long term outcome of surgical treatment was most favorable, radiofrequency neurotomy and nerve block can be considered for the secondary management of elderly lumbar spinals stenosis patients.
Demographics of patients
Nerve Block | RF | Surgery | |
---|---|---|---|
Number of Patients | 253 | 56 | 62 |
Age, years, mean±SD | 70.6±4.5 | 72.2±1.9 | 69.4±6.0 |
Sex, n (M:F) | 80:173 | 19:37 | 28:34 |
*RF: Radiofrequency neurotomy
Clinical manifestation of each treatment
Nerve Block | RF | Surgery | |
---|---|---|---|
Claudication | 26 (10%) | 3 (5%) | 16 (26%) |
Radicular Pain | 113 (45%) | 41 (73%) | 32 (52%) |
Back pain | 114 (45%) | 12 (22%) | 14 (22%) |
*RF: Radiofrequency neurotomy
Clinical results: VAS
Pre-treatment | 1 month later | |
---|---|---|
Nerve Block | 6.9±1.2 | 3.7±1.4 |
RF | 7.4±0.6 | 3.4±0.8 |
Surgery | 7.5±0.5 | 3.4±0.4 |
*RF: Radiofrequency neurotomy
Clinical outcomes: Odom’s criteria
Nerve Block | RF | OP | |
---|---|---|---|
Excellent or Good | 162 (64%) | 40 (71%) | 46 (74%) |
Poor | 20 (8%) | 2 (3%) | 3 (5%) |
Retreatment | 101 (40%) | 3 (5%) | 2 (3%) |
*RF: Radiofrequency neurotomy