Spinal Metastasis of Cerebral Glioblastoma Report of Two Cases

Case Report

Korean J Spine 2004;1(4): 519-523.

Jae-Won Jang, M.D., Jung-Kil Lee, M.D., Soo-Han Kim, M.D., Sung-Pil Joo, M.D., Tae-Sun Kim, M.D., Jae-Hyoo Kim, M.D. and Je-Hyuk Lee, M.D.

Department of Neurosurgery, Chonnam National University Hospital & Medical School, Gwangju, Korea

척수로 전이된 교모세포종 2예

장재원^, 이정길^, 김수한^, 주성필^, 김태선^, 김재휴^, 이제혁

전남대학교 의과대학 신경외과학교실

Abstract

Symptomatic spinal metastases of glioblastoma multiforme(GM) are rarely described. We present two cases of spinal lepto- meningeal metastases of GM. One case is a 57-year-old man who presented with radicular pain 6 months after the surgery and radiation therapy of cerebral glioblastoma. The magnetic resonance image(MRI) of lumbar spine revealed an intradural mass at the cauda equina. The tumor was removed subtotally with L2-4 hemipartial laminectomy and histologic diagnosis was giloblastoma. External beam radiation therapy(30Gy) was followed. The other case is a 50-year-old woman who developed paresthesia and motor weakness on her left leg and urinary and fecal difficulty followed the brain surgery for cerebral glioblas- toma 9 months ago. The thoracolumbar MRI demonstrated multiple intradural masses through the entire thoracolumbar spinal cord. L1-2 total laminectomy and biopsy. Were performed, and the histologic diagnosis was giloblastoma.

Keywords: Glioblastoma, Spinal metastasis