Neurospine

Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.

The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Essay

December 31, 2020

History of Spinal Neurosurgery and Spine Societies

Mehmet Zileli, Salman Sharif, Maurizio Fornari, Premenand Ramani, Fengzeng Jian, Richard Fessler, Se-Hoon Kim, Toshihiro Takami, Nobuyuki Shimokawa, Gilbert Dechambenoit, et al.

Neurospine. 2020;17(4):675-694.

Essay

December 31, 2020

The Art of Diagnosis in the Cervical Spine

Melvin C. Makhni, Caleb M. Yeung, K. Daniel Riew

Neurospine. 2020;17(4):695-703.

Review Article

December 31, 2020

Early Management of Cervical Spine Trauma: WFNS Spine Committee Recommendations

Mehmet Zileli, Enrique Osorio-Fonseca, Nikolay Konovalov, Carlos Cardenas-Jalabe, Stanislav Kaprovoy, Sergey Mlyavykh, Artur Pogosyan

Neurospine. 2020;17(4):710-722.

Epidemiology, prevention, early management of cervical spine trauma and it's reduction are the objectives of this review paper. A PubMed and MEDLINE search between 2009 and 2019 were conducted using...

Review Article

December 31, 2020

Upper Cervical Spine Trauma: WFNS Spine Committee Recommendations

Oscar L. Alves, Leopoldina Pereira, Se-Hoon Kim, Andrey Grin, Nobuyuki Shimokawa, Nikolay Konovalov, Mehmet Zileli

Neurospine. 2020;17(4):723-736.

Craniovertebral junction (CVJ) trauma is a challenging clinical condition. Being a highly mobile functional unit at the junction of the skull and the vertebral column, traumatic events in this area...

Review Article

December 31, 2020

Subaxial Cervical Spine Injuries: WFNS Spine Committee Recommendations

Salman Sharif, Muhammad Yassar Jazaib Ali, Ibet Marie Y. Sih, Jutty Parthiban, Óscar L. Alves

Neurospine. 2020;17(4):737-758.

To formulate specific guidelines for the recommendation of subaxial cervical spine injuries concerning classification, management, posttraumatic locked facets and vertebral artery injury. Computerized literature was searched on PubMed and google...

Review Article

December 31, 2020

Early Management of Spinal Cord Injury: WFNS Spine Committee Recommendations

José Antonio Soriano Sánchez, Salman Sharif, Francesco Costa, Jose Alberto Israel Romero Rangel, Carla Daniela Anania, Mehmet Zileli

Neurospine. 2020;17(4):759-784.

Scientific knowledge today is being generated more rapidly than we can assimilate thus requiring continuous review of gold-standards for diagnosis and treatment of specific pathologies. The aim of this paper...

Review Article

December 31, 2020

Pharmacologic and Regenerative Cell Therapy for Spinal Cord Injury: WFNS Spine Committee Recommendations

Toshihiro Takami, Nobuyuki Shimokawa, Jutty Parthiban, Mehmet Zileli, Sheena Ali

Neurospine. 2020;17(4):785-796.

This is a review article examining the pharmacologic and regenerative cell therapy for spinal cord injury. A literature search during last 10 years were conducted using key words. Case reports,...

Review Article

December 31, 2020

Pediatric Cervical Spine Injuries and SCIWORA: WFNS Spine Committee Recommendations

Nikolay Konovalov, Nikolay Peev, Mehmet Zileli, Salman Sharif, Stanislav Kaprovoy, Stanislav Timonin

Neurospine. 2020;17(4):797-808.

Cervical trauma in children have variations from the adults mainly due to anatomic differences. An optimal diagnostic and treatment strategy is critical, particularly when there is a lack of standardized...

Review Article

December 31, 2020

Outcomes of Spinal Cord Injury: WFNS Spine Committee Recommendations

Jutty Parthiban, Mehmet Zileli, Salman Yousuf Sharif

Neurospine. 2020;17(4):809-819.

This comprehensive review article aims to provide some definitive statements on the factors like clinical syndromes, radiological findings, and decompressive surgery, that may influence the outcomes in cervical spinal cord...

Review Article

December 31, 2020

Rehabilitation of Spinal Cord Injury: WFNS Spine Committee Recommendations

Nikolay Peev, Alexander Komarov, Enrique Osorio-Fonseca, Mehmet Zileli

Neurospine. 2020;17(4):820-832.

Spinal cord injury (SCI) is accompanied by a significant number of complications associated with damage to the spinal cord, gross functional impairments leading to limited self-care and movement, leading to...

Review Article

December 31, 2020

Cervical Deformity: Evaluation, Classification, and Surgical Planning

Ahilan Sivaganesan, Justin S. Smith, Han Jo Kim

Neurospine. 2020;17(4):833-842.

Cervical deformity is a challenging condition to treat and requires complex decision-making. Apart from a thorough history and physical examination, a thoughtful and quantitative analysis of multiple imaging modalities is...

Original Article

December 31, 2020

Weak Ligaments and Sloping Joints: A New Hypothesis for Development of Congenital Atlantoaxial Dislocation and Basilar Invagination

Avnish K. Chauhan, P. Sarat Chandra, Nishant Goyal, Madhumita R. Chowdhury, Jyotirmoy Banerjee, Manjari Tripathi, Madhulika Kabra

Neurospine. 2020;17(4):843-856.

Objective: Developmental bony craniovertebral junction (CVJ) anomalies seem to have a genetic basis and also abnormal joint morphology causing atlantoaxial dislocation (AAD) and basilar invagination (BI). Methods: DNA extracted polymerase chain...

Original Article

December 31, 2020

Longitudinal Evaluation of Patient-Reported Outcomes Measurement Information System for Back and Leg Pain in Minimally Invasive Transforaminal Lumbar Interbody Fusion

Nathaniel W. Jenkins, James M. Parrish, Nadia M. Hrynewycz, Thomas S. Brundage, Kern Singh

Neurospine. 2020;17(4):862-870.

Objective: While visual analogue score (VAS) metrics are among the most universally adopted patient-reported outcome measures (PROMs), there is limited research on the influence of back and leg pain on...

Original Article

December 31, 2020

Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis

Anoop R. Galivanche, Raj Gala, Preetpaul S. Bagi, Arianne J. Boylan, Christopher M. Dussik, Pedro D. Coutinho, Jonathan N. Grauer, Arya G. Varthi

Neurospine. 2020;17(4):871-878.

Objective: To compare the perioperative morbidity of 2-level anterior cervical discectomy and fusion (ACDF) with that of 1-level anterior cervical corpectomy and fusion (ACCF) for the treatment of cervical degenerative...

Original Article

December 31, 2020

Chronic Opioid Use Following Lumbar Discectomy: Prevalence, Risk Factors, and Current Trends in the United States

Andrew B. Harris, Bo Zhang, Majd Marrache, Varun Puvanesarajah, Micheal Raad, Hamid Hassanzadeh, Mark Bicket, Amit Jain

Neurospine. 2020;17(4):879-887.

Objective: Lumbar discectomy is commonly performed for symptomatic lumbar disc herniation. We aimed to examine prescribing patterns and risk factors for chronic opioid use following lumbar discectomy. Methods: Using a private...

Original Article

December 31, 2020

Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis

Lauren K. Dunn, Ching-Jen Chen, Davis G. Taylor, Kamilla Esfahani, Brian Brenner, Charles Luo, Thomas J. Buell, Sarah N. Spangler, Avery L. Buchholz, Justin S. Smith, et al.

Neurospine. 2020;17(4):888-895.

Objective: This was a retrospective, cohort study investigating the efficacy and safety of continuous low-dose postoperative tranexamic acid (PTXA) on drain output and transfusion requirements following adult spinal deformity surgery. Methods:...

Original Article

December 31, 2020

Synthetic Cages Associated With Increased Rates of Revision Surgery and Higher Costs Compared to Allograft in ACDF in the Nonelderly Patient

Majd Marrache, Rachel Bronheim, Andrew B. Harris, Varun Puvanesarajah, Micheal Raad, Sang Lee, Richard Skolasky, Amit Jain

Neurospine. 2020;17(4):896-901.

Objective: The aim of this study was to compare all-cause reoperation rates and costs in nonelderly patients treated with anterior cervical discectomy and fusion (ACDF) with structural allograft versus synthetic...

Original Article

December 31, 2020

Selection of the Lowest Instrumented Vertebra and Relative Odds Ratio of Distal Adding-on for Lenke Type 1A and 2A Curves in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis

Che-Wei Liu, Lawrence G. Lenke, Lee A. Tan, Taemin Oh, Kou-Hua Chao, Shi-Ding Lin, Ru-Yu Pan

Neurospine. 2020;17(4):902-909.

Objective: To examine existing literature and pool the data to determine the relative odds ratio of “adding-on” (AO) based on various reported criteria for lower instrumented vertebra (LIV) selection in...

Original Article

December 31, 2020

Methods and Early Clinical Results of Percutaneous Lumbar Interbody Fusion

Shu Nakamura, Fjio Ito, Zenya Ito, Motohide Shibayama

Neurospine. 2020;17(4):910-920.

Objective: Percutaneous lumbar interbody fusion (PELIF) is a procedure that includes the use of new devices, which allow minimally invasive diskectomy under the percutaneous full-endoscopic guidance and safe percutaneous insertion...

Original Article

December 31, 2020

Feasibility of the Far Lateral Suboccipital Approach to the Retroodontoid Region. How Much Bone Removal Is Truly Needed?

Gergely Bodon, Kristof Kiraly, Tamas Ruttkay, Bernhard Hirt, Heiko Koller

Neurospine. 2020;17(4):921-928.

Objective: The posterolateral extradural suboccipital approach can be used to reach the anterior epidural space and the retro-odontoid regions. The extent of necessary bone removal of the atlas vertebra (C1)...

Technical Note

December 31, 2020

Transforaminal Endoscopic Discectomy for Large, Two Level Calcified, Thoracic Disc Herniations With 5-Year Follow-up

Karlo Houra, Robert Saftic

Neurospine. 2020;17(4):954-959.

To describe technical details and benefits of transforaminal endoscopic discectomy for treatment of patients with large, dorsomedial, calcified thoracic disc herniations at 2 levels and to report on their clinical...

A Neurospine Surgeon With the Mind of a Neuroscientist: Makoto Taniguchi, MD, PhD (1958–2020) Phyo Kim Neurospine. 2020;17(4):673-674. Editorial December 31, 2020 Full text PubReader ePub PDF	History of Spinal Neurosurgery and Spine Societies Mehmet Zileli, Salman Sharif, Maurizio Fornari, Premenand Ramani, Fengzeng Jian, Richard Fessler, Se-Hoon Kim, Toshihiro Takami, Nobuyuki Shimokawa, Gilbert Dechambenoit, et al. Neurospine. 2020;17(4):675-694. Essay December 31, 2020 Full text PubReader ePub PDF
The Art of Diagnosis in the Cervical Spine Melvin C. Makhni, Caleb M. Yeung, K. Daniel Riew Neurospine. 2020;17(4):695-703. Essay December 31, 2020 Full text PubReader ePub PDF	Cervical Spine Trauma and Spinal Cord Injury Recommendations of WFNS Spine Committee Mehmet Zileli, Nikolay Konovalov, Salman Sharif Neurospine. 2020;17(4):704-707. Introduction December 31, 2020 Full text PubReader ePub PDF
Finding a Better Way to Manage Cervical Spine Trauma and Spinal Cord Injury Se-Hoon Kim Neurospine. 2020;17(4):708-709. Editorial December 31, 2020 Full text PubReader ePub PDF	Early Management of Cervical Spine Trauma: WFNS Spine Committee Recommendations Mehmet Zileli, Enrique Osorio-Fonseca, Nikolay Konovalov, Carlos Cardenas-Jalabe, Stanislav Kaprovoy, Sergey Mlyavykh, Artur Pogosyan Neurospine. 2020;17(4):710-722. Review Article December 31, 2020 Full text PubReader ePub PDF
Upper Cervical Spine Trauma: WFNS Spine Committee Recommendations Oscar L. Alves, Leopoldina Pereira, Se-Hoon Kim, Andrey Grin, Nobuyuki Shimokawa, Nikolay Konovalov, Mehmet Zileli Neurospine. 2020;17(4):723-736. Review Article December 31, 2020 Full text PubReader ePub PDF	Subaxial Cervical Spine Injuries: WFNS Spine Committee Recommendations Salman Sharif, Muhammad Yassar Jazaib Ali, Ibet Marie Y. Sih, Jutty Parthiban, Óscar L. Alves Neurospine. 2020;17(4):737-758. Review Article December 31, 2020 Full text PubReader ePub PDF
Early Management of Spinal Cord Injury: WFNS Spine Committee Recommendations José Antonio Soriano Sánchez, Salman Sharif, Francesco Costa, Jose Alberto Israel Romero Rangel, Carla Daniela Anania, Mehmet Zileli Neurospine. 2020;17(4):759-784. Review Article December 31, 2020 Full text PubReader ePub PDF	Pharmacologic and Regenerative Cell Therapy for Spinal Cord Injury: WFNS Spine Committee Recommendations Toshihiro Takami, Nobuyuki Shimokawa, Jutty Parthiban, Mehmet Zileli, Sheena Ali Neurospine. 2020;17(4):785-796. Review Article December 31, 2020 Full text PubReader ePub PDF
Pediatric Cervical Spine Injuries and SCIWORA: WFNS Spine Committee Recommendations Nikolay Konovalov, Nikolay Peev, Mehmet Zileli, Salman Sharif, Stanislav Kaprovoy, Stanislav Timonin Neurospine. 2020;17(4):797-808. Review Article December 31, 2020 Full text PubReader ePub PDF	Outcomes of Spinal Cord Injury: WFNS Spine Committee Recommendations Jutty Parthiban, Mehmet Zileli, Salman Yousuf Sharif Neurospine. 2020;17(4):809-819. Review Article December 31, 2020 Full text PubReader ePub PDF
Rehabilitation of Spinal Cord Injury: WFNS Spine Committee Recommendations Nikolay Peev, Alexander Komarov, Enrique Osorio-Fonseca, Mehmet Zileli Neurospine. 2020;17(4):820-832. Review Article December 31, 2020 Full text PubReader ePub PDF	Cervical Deformity: Evaluation, Classification, and Surgical Planning Ahilan Sivaganesan, Justin S. Smith, Han Jo Kim Neurospine. 2020;17(4):833-842. Review Article December 31, 2020 Full text PubReader ePub PDF
Weak Ligaments and Sloping Joints: A New Hypothesis for Development of Congenital Atlantoaxial Dislocation and Basilar Invagination Avnish K. Chauhan, P. Sarat Chandra, Nishant Goyal, Madhumita R. Chowdhury, Jyotirmoy Banerjee, Manjari Tripathi, Madhulika Kabra Neurospine. 2020;17(4):843-856. Original Article December 31, 2020 Cited By 1 Full text PubReader ePub PDF	Commentary on “Weak Ligaments and Sloping Joints: A New Hypothesis for Development of Congenital Atlantoaxial Dislocation and Basilar Invagination” Lingbo Kong Neurospine. 2020;17(4):857-858. Editorial December 31, 2020 Full text PubReader ePub PDF
From Anatomic to Genetic Understanding of Developmental Craniovertebral Junction Abnormalities Alexander E. Ropper Neurospine. 2020;17(4):859-861. Editorial December 31, 2020 Full text PubReader ePub PDF	Longitudinal Evaluation of Patient-Reported Outcomes Measurement Information System for Back and Leg Pain in Minimally Invasive Transforaminal Lumbar Interbody Fusion Nathaniel W. Jenkins, James M. Parrish, Nadia M. Hrynewycz, Thomas S. Brundage, Kern Singh Neurospine. 2020;17(4):862-870. Original Article December 31, 2020 Full text PubReader ePub PDF
Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis Anoop R. Galivanche, Raj Gala, Preetpaul S. Bagi, Arianne J. Boylan, Christopher M. Dussik, Pedro D. Coutinho, Jonathan N. Grauer, Arya G. Varthi Neurospine. 2020;17(4):871-878. Original Article December 31, 2020 Full text PubReader ePub PDF	Chronic Opioid Use Following Lumbar Discectomy: Prevalence, Risk Factors, and Current Trends in the United States Andrew B. Harris, Bo Zhang, Majd Marrache, Varun Puvanesarajah, Micheal Raad, Hamid Hassanzadeh, Mark Bicket, Amit Jain Neurospine. 2020;17(4):879-887. Original Article December 31, 2020 Full text PubReader ePub PDF Supplementary Material
Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis Lauren K. Dunn, Ching-Jen Chen, Davis G. Taylor, Kamilla Esfahani, Brian Brenner, Charles Luo, Thomas J. Buell, Sarah N. Spangler, Avery L. Buchholz, Justin S. Smith, et al. Neurospine. 2020;17(4):888-895. Original Article December 31, 2020 Full text PubReader ePub PDF Supplementary Material	Synthetic Cages Associated With Increased Rates of Revision Surgery and Higher Costs Compared to Allograft in ACDF in the Nonelderly Patient Majd Marrache, Rachel Bronheim, Andrew B. Harris, Varun Puvanesarajah, Micheal Raad, Sang Lee, Richard Skolasky, Amit Jain Neurospine. 2020;17(4):896-901. Original Article December 31, 2020 Full text PubReader ePub PDF Supplementary Material
Selection of the Lowest Instrumented Vertebra and Relative Odds Ratio of Distal Adding-on for Lenke Type 1A and 2A Curves in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis Che-Wei Liu, Lawrence G. Lenke, Lee A. Tan, Taemin Oh, Kou-Hua Chao, Shi-Ding Lin, Ru-Yu Pan Neurospine. 2020;17(4):902-909. Original Article December 31, 2020 Cited By 1 Full text PubReader ePub PDF Supplementary Material	Methods and Early Clinical Results of Percutaneous Lumbar Interbody Fusion Shu Nakamura, Fjio Ito, Zenya Ito, Motohide Shibayama Neurospine. 2020;17(4):910-920. Original Article December 31, 2020 Full text PubReader ePub PDF
Feasibility of the Far Lateral Suboccipital Approach to the Retroodontoid Region. How Much Bone Removal Is Truly Needed? Gergely Bodon, Kristof Kiraly, Tamas Ruttkay, Bernhard Hirt, Heiko Koller Neurospine. 2020;17(4):921-928. Original Article December 31, 2020 Full text PubReader ePub PDF	Cervical Arthroplasty in the Treatment of Cervical Angina: Case Report and Review of the Literature Omar M. Al Jammal, Luis Daniel Diaz-Aguilar, Shanmukha Srinivas, Jillian Plonsker, Ronald Sahyouni, Martin H. Pham Neurospine. 2020;17(4):929-938. Case Report December 31, 2020 Full text PubReader ePub PDF
Cervical Angina Lee A. Tan Neurospine. 2020;17(4):939-940. Editorial December 31, 2020 Full text PubReader ePub PDF	Management of Pseudarthrosis With Implant Failure at a Multilevel Vertebral Column Resection Site: A Case Report Venkat Boddapati, Joseph M. Lombardi, Lawrence G. Lenke Neurospine. 2020;17(4):941-946. Case Report December 31, 2020 Full text PubReader ePub PDF
Arteriovenous Fistula at the Craniocervical Junction Found After Cervical Laminoplasty for Ossification of the Posterior Longitudinal Ligament Susumu Sasada, Masafumi Hiramatsu, Akira Kusumegi, Haruto Fujimura, Shogo Oshikata, Yuichi Takahashi, Kenki Nishida, Takao Yasuhara, Isao Date Neurospine. 2020;17(4):947-953. Case Report December 31, 2020 Full text PubReader ePub PDF	Transforaminal Endoscopic Discectomy for Large, Two Level Calcified, Thoracic Disc Herniations With 5-Year Follow-up Karlo Houra, Robert Saftic Neurospine. 2020;17(4):954-959. Technical Note December 31, 2020 Full text PubReader ePub PDF
A Submandibular Retropharyngeal Approach Improves Surgical Exposure Henri Salle, François Caire Neurospine. 2020;17(4):960-962. Letter to the Editor December 31, 2020 Full text PubReader ePub PDF