Neurospine

Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.

The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Review Article

March 31, 2022

Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations

J.C. Le Huec, S. AlEissa, A.J. Bowey, B. Debono, A. El-Shawarbi, N. Fernández-Baillo, K.S. Han, A. Martin-Benlloch, R. Pflugmacher, P. Sabatier, et al.

Neurospine. 2022;19(1):1-12.

Bleeding in spine surgery is a common occurrence but when bleeding is uncontrolled the consequences can be severe due to the potential for spinal cord compression and damage to the...

Review Article

February 2, 2022

Glioma Immunotherapy: Advances and Challenges for Spinal Cord Gliomas

Clare Grady, Kaitlyn Melnick, Ken Porche, Farhad Dastmalchi, Daniel J. Hoh, Maryam Rahman, Ashley Ghiaseddin

Neurospine. 2022;19(1):13-29.

Spinal cord gliomas are rare entities that often have limited surgical options. Immunotherapy has shown promise in intracranial gliomas with some research suggesting benefit for spinal cord gliomas. A focused...

Original Article

January 30, 2022

Remnant Tumor Margin as Predictive Factor for Its Growth After Incomplete Resection of Cervical Dumbbell-Shaped Schwannomas

Kazuya Kitamura, Narihito Nagoshi, Osahiko Tsuji, Satoshi Suzuki, Satoshi Nori, Eijiro Okada, Mitsuru Yagi, Morio Matsumoto, Masaya Nakamura, Kota Watanabe

Neurospine. 2022;19(1):32-40.

Objective: The purpose of our study was to investigate the risk factors of remnant tumor growth after incomplete resection (IR) of cervical dumbbell-shaped schwannomas (DS). Methods: Twenty-one patients with IR of...

Original Article

January 30, 2022

Steroids in the Management of Preoperative Neurological Deficits in Metastatic Spine Disease: Results From the EPOSO Study

Anne L. Versteeg, Lior M. Elkaim, Arjun Sahgal, Laurence D. Rhines, Daniel M. Sciubba, James M. Schuster, Michael G. Fehlings, Aron Lazary, Michelle J. Clarke, Paul M. Arnold, et al.

Neurospine. 2022;19(1):43-50.

Objective: Patients presenting with neurological deficit secondary to metastatic epidural spinal cord compression (MESCC) are often treated with surgery in combination with high-dose corticosteroids. Despite steroids being commonly used, the...

Original Article

February 2, 2022

Frailty Status Is a More Robust Predictor Than Age of Spinal Tumor Surgery Outcomes: A NSQIP Analysis of 4,662 Patients

Syed Faraz Kazim, Alis J. Dicpinigaitis, Christian A. Bowers, Smit Shah, William T. Couldwell, Rachel Thommen, Daniel J. Alvarez-Crespo, Matthew Conlon, Omar H. Tarawneh, John Vellek, et al.

Neurospine. 2022;19(1):53-62.

Objective: The present study aimed to evaluate the effect of baseline frailty status (as measured by modified frailty index-5 [mFI-5]) versus age on postoperative outcomes of patients undergoing surgery for...

Original Article

February 3, 2022

Clinical Features, Treatments, and Prognosis of Intramedullary Spinal Cord Metastases From Lung Cancer: A Case Series and Systematic Review

Liang Wu, Li'ao Wang, Jun Yang, Wenqing Jia, Yulun Xu

Neurospine. 2022;19(1):65-76.

Objective: Intramedullary spinal cord metastasis from lung cancer (ISCM-LC) are increasing in prevalence. We aim to investigate its clinical features, treatments and prognosis. Methods: We reported 6 ISCM-LC cases and conducted...

Original Article

January 17, 2022

Recovery Potential of Spinal Meningioma Patients With Preoperative Loss of Walking Ability Following Surgery – A Retrospective Single-Center Study

Ville Vasankari, Roel Haeren, Mika Niemelä, Miikka Korja

Neurospine. 2022;19(1):77-83.

Objective: Spinal meningiomas are neurosurgical rarities that manifest with progressive paraor tetraparesis. The effect of timing of surgery on the recovery after the loss of walking ability is poorly known....

Original Article

March 31, 2022

Hardware Failure in Spinal Tumor Surgery: A Hallmark of Longer Survival?

Nikita Zaborovskii, Adam Schlauch, Dmitrii Ptashnikov, Dmitrii Mikaylov, Sergei Masevnin, Oleg Smekalenkov, John Shapton, Dimitriy Kondrashov

Neurospine. 2022;19(1):84-95.

Objective: Instrumentation failure in spine tumor surgery is a common reason for revision operation. Increases in patient survival demand a better understanding of the hardware longevity. The study objective was...

Original Article

March 31, 2022

Functional Outcome After Spinal Meningioma Surgery. A Nationwide Population-Based Study

Charles Champeaux-Depond, Nicolas Penet, Joconde Weller, Jean-Charles Le Huec, Vincent Jecko

Neurospine. 2022;19(1):96-107.

Objective: To describe and analysed the functional outcome (FO) after spinal meningioma (SM) surgery. Methods: We processed the système national des données de santé (SNDS) i.e. , the French national administrative...

Original Article

March 31, 2022

Intramedullary Spinal Cord Lesions: A Single-Center Experience

Vincent Jecko, Paul Roblot, Lorenzo Mongardi, Morgan Ollivier, Natalia Delgado Piccoli, Thomas Charleux, Thomas Wavasseur, Edouard Gimbert, Dominique Liguoro, Guillaume Chotard, et al.

Neurospine. 2022;19(1):108-117.

Objective: Spinal cord tumors constitute a small part of spinal surgery owing to their rarity. This retrospective study describes their current management. Methods: Forty-eight patients were treated for an intramedullary tumor...

Original Article

March 31, 2022

Long-term Neurologic Outcome After Spinal Ependymoma Resection With Multimodal Intraoperative Electrophysiological Recording: Cohort Study and Review of the Literature

Grégoire P. Chatain, Michael W. Kortz, Stephanie Serva, Keshari Shrestha, Patrick Hosokawa, Timothy H. Ung, Michael Finn

Neurospine. 2022;19(1):118-132.

Objective: To evaluate how multimodal intraoperative neuromonitoring (IONM) changes during spinal ependymoma (SE) resection correlate with long-term neuro-functional outcomes. Methods: A retrospective analysis of patients aged 18 years or older who...

Original Article

March 31, 2022

Prediction of Discharge Status and Readmissions after Resection of Intradural Spinal Tumors

Michael C. Jin, Allen L. Ho, Austin Y. Feng, Zachary A. Medress, Arjun V. Pendharkar, Paymon Rezaii, John K. Ratliff, Atman M. Desai

Neurospine. 2022;19(1):133-145.

Objective: Intradural spinal tumors are uncommon and while associations between clinical characteristics and surgical outcomes have been explored, there remains a paucity of literature unifying diverse predictors into an integrated...

Original Article

March 31, 2022

Mechanical Failure After Total En Bloc Spondylectomy and Salvage Surgery

Shin Won Kwon, Chun Kee Chung, Young Il Won, Woon Tak Yuh, Sung Bae Park, Seung Heon Yang, Chang Hyun Lee, John M. Rhee, Kyoung-Tae Kim, Chi Heon Kim

Neurospine. 2022;19(1):146-154.

Objective: Total en bloc spondylectomy (TES) is a curative surgical method for spinal tumors. After resecting the 3 spinal columns, reconstruction is of paramount importance. We present cases of mechanical...

Review Article

March 31, 2022

Pearls and Pitfalls of Oblique Lateral Interbody Fusion: A Comprehensive Narrative Review

Hyoungmin Kim, Bong-Soon Chang, Sam Yeol Chang

Neurospine. 2022;19(1):163-176.

Lumbar degenerative disease is a common problem in an aging society. Oblique lateral interbody fusion (OLIF) is a minimally invasive surgical (MIS) technique that utilizes a retroperitoneal antepsoas corridor to...

Review Article

January 29, 2022

Clinical Issues in Indication, Correction, and Outcomes of the Surgery for Neuromuscular Scoliosis: Narrative Review in Pedicle Screw Era

Hak Sun Kim, Ji Won Kwon, Kun-Bo Park

Neurospine. 2022;19(1):177-187.

Surgical treatment for neuromuscular scoliosis has evolved with pedicle screw instrumentation and the improvement of perioperative management. We aimed to review recent papers related to posterior surgical correction with a...

Original Article

January 2, 2022

Location Distribution of Fistulas and Surgical Strategies for Spinal Extradural Meningeal Cysts: A Retrospective Analysis of 30 Cases at a Single Center

Qiang Jian, Gang Song, Zhenlei Liu, Wanru Duan, Jian Guan, Fengzeng Jian, Zan Chen

Neurospine. 2022;19(1):188-201.

Objective: This study aimed to illustrate the features of fistula location distribution, surgical strategies, and outcomes in spinal epidural meningeal cysts (SEMCs). Methods: The authors searched and reviewed the medical records...

Original Article

February 2, 2022

Reconstruction of the Cervical Lateral Mass Using 3-Dimensional-Printed Prostheses

Qiang Jian, Zhenlei Liu, Wanru Duan, Jian Guan, Fengzeng Jian, Zan Chen

Neurospine. 2022;19(1):202-211.

Objective: This study aimed to investigate the outcome of using 3-dimensional (3D)-printed prostheses to reconstruct a cervical lateral mass to maintain cervical stability. Methods: We retrospectively analyzed data of 7 patients...

Original Article

February 2, 2022

Comparative Analysis of 3 Types of Minimally Invasive Posterior Cervical Foraminotomy for Foraminal Stenosis, Uniportal-, Biportal Endoscopy, and Microsurgery: Radiologic and Midterm Clinical Outcomes

Ji Yeon Kim, Hyun Jin Hong, Dong Chan Lee, Tae Hyun Kim, Jin Seob Hwang, Choon Keun Park

Neurospine. 2022;19(1):212-223.

Objective: The aim of this study was to compare the clinical and radiologic outcomes of 3 types of minimally invasive posterior cervical foraminotomy (PCF): uniportal endoscopic surgery, biportal endoscopic surgery,...

Original Article

March 31, 2022

Risk Factors for Poor Outcomes Following Minimally Invasive Discectomy: A Post Hoc Subgroup Analysis of 2-Year Follow-up Prospective Data

Zihao Chen, Lei He, Lijun Huang, Zhongyu Liu, Jianwen Dong, Bin Liu, Ruiqiang Chen, Liangming Zhang, Peigen Xie, Limin Rong

Neurospine. 2022;19(1):224-235.

Objective: A post hoc subgroup analysis of prospectively collected data from a randomized controlled trial was conducted to identify risk factors related to poor outcomes in patients who underwent minimally...

Original Article

March 31, 2022

The Last Touched Vertebra on Supine Radiographs Can Be the Optimal Lower Instrumented Vertebra in Adolescent Idiopathic Scoliosis Patients

Do-Hyoung Kim, Seung-Jae Hyun, Chang-Hyun Lee, Ki-Jeong Kim

Neurospine. 2022;19(1):236-243.

Objective: To determine whether the last touched vertebra (LTV) on supine radiographs is suitable for the lower instrumented vertebra (LIV) in adolescent idiopathic scoliosis (AIS) correction surgery. Methods: In total, 57...

Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations J.C. Le Huec, S. AlEissa, A.J. Bowey, B. Debono, A. El-Shawarbi, N. Fernández-Baillo, K.S. Han, A. Martin-Benlloch, R. Pflugmacher, P. Sabatier, et al. Neurospine. 2022;19(1):1-12. Review Article March 31, 2022 Full text PubReader ePub PDF	Glioma Immunotherapy: Advances and Challenges for Spinal Cord Gliomas Clare Grady, Kaitlyn Melnick, Ken Porche, Farhad Dastmalchi, Daniel J. Hoh, Maryam Rahman, Ashley Ghiaseddin Neurospine. 2022;19(1):13-29. Review Article February 2, 2022 Cited By 2 Full text PubReader ePub PDF
Another Milestone for Spinal Intramedullary Tumor Treatment Chi Heon Kim Neurospine. 2022;19(1):30-31. Editorial March 31, 2022 Full text PubReader ePub PDF	Remnant Tumor Margin as Predictive Factor for Its Growth After Incomplete Resection of Cervical Dumbbell-Shaped Schwannomas Kazuya Kitamura, Narihito Nagoshi, Osahiko Tsuji, Satoshi Suzuki, Satoshi Nori, Eijiro Okada, Mitsuru Yagi, Morio Matsumoto, Masaya Nakamura, Kota Watanabe Neurospine. 2022;19(1):32-40. Original Article January 30, 2022 Cited By 1 Full text PubReader ePub PDF
Commentary on “Remnant Tumor Margin as Predictive Factor for Its Growth After Incomplete Resection of Cervical Dumbbell-Shaped Schwannomas” Toshiki Endo Neurospine. 2022;19(1):41-42. Editorial March 31, 2022 Full text PubReader ePub PDF	Steroids in the Management of Preoperative Neurological Deficits in Metastatic Spine Disease: Results From the EPOSO Study Anne L. Versteeg, Lior M. Elkaim, Arjun Sahgal, Laurence D. Rhines, Daniel M. Sciubba, James M. Schuster, Michael G. Fehlings, Aron Lazary, Michelle J. Clarke, Paul M. Arnold, et al. Neurospine. 2022;19(1):43-50. Original Article January 30, 2022 Cited By 1 Full text PubReader ePub PDF
Commentary on “Steroids in the Management of Preoperative Neurological Deficits in Metastatic Spine Disease: Results From the EPOSO Study” John H. Shin Neurospine. 2022;19(1):51-52. Editorial March 31, 2022 Full text PubReader ePub PDF	Frailty Status Is a More Robust Predictor Than Age of Spinal Tumor Surgery Outcomes: A NSQIP Analysis of 4,662 Patients Syed Faraz Kazim, Alis J. Dicpinigaitis, Christian A. Bowers, Smit Shah, William T. Couldwell, Rachel Thommen, Daniel J. Alvarez-Crespo, Matthew Conlon, Omar H. Tarawneh, John Vellek, et al. Neurospine. 2022;19(1):53-62. Original Article February 2, 2022 Cited By 1 Full text PubReader ePub PDF
Commentary on “Frailty Status Is a More Robust Predictor Than Age of Spinal Tumor Surgery Outcomes: A NSQIP Analysis of 4,662 Patients” Moon-Jun Sohn Neurospine. 2022;19(1):63-64. Editorial March 31, 2022 Full text PubReader ePub PDF	Clinical Features, Treatments, and Prognosis of Intramedullary Spinal Cord Metastases From Lung Cancer: A Case Series and Systematic Review Liang Wu, Li'ao Wang, Jun Yang, Wenqing Jia, Yulun Xu Neurospine. 2022;19(1):65-76. Original Article February 3, 2022 Full text PubReader ePub PDF
Recovery Potential of Spinal Meningioma Patients With Preoperative Loss of Walking Ability Following Surgery – A Retrospective Single-Center Study Ville Vasankari, Roel Haeren, Mika Niemelä, Miikka Korja Neurospine. 2022;19(1):77-83. Original Article January 17, 2022 Cited By 1 Full text PubReader ePub PDF	Hardware Failure in Spinal Tumor Surgery: A Hallmark of Longer Survival? Nikita Zaborovskii, Adam Schlauch, Dmitrii Ptashnikov, Dmitrii Mikaylov, Sergei Masevnin, Oleg Smekalenkov, John Shapton, Dimitriy Kondrashov Neurospine. 2022;19(1):84-95. Original Article March 31, 2022 Full text PubReader ePub PDF
Functional Outcome After Spinal Meningioma Surgery. A Nationwide Population-Based Study Charles Champeaux-Depond, Nicolas Penet, Joconde Weller, Jean-Charles Le Huec, Vincent Jecko Neurospine. 2022;19(1):96-107. Original Article March 31, 2022 Full text PubReader ePub PDF Supplementary Material	Intramedullary Spinal Cord Lesions: A Single-Center Experience Vincent Jecko, Paul Roblot, Lorenzo Mongardi, Morgan Ollivier, Natalia Delgado Piccoli, Thomas Charleux, Thomas Wavasseur, Edouard Gimbert, Dominique Liguoro, Guillaume Chotard, et al. Neurospine. 2022;19(1):108-117. Original Article March 31, 2022 Full text PubReader ePub PDF
Long-term Neurologic Outcome After Spinal Ependymoma Resection With Multimodal Intraoperative Electrophysiological Recording: Cohort Study and Review of the Literature Grégoire P. Chatain, Michael W. Kortz, Stephanie Serva, Keshari Shrestha, Patrick Hosokawa, Timothy H. Ung, Michael Finn Neurospine. 2022;19(1):118-132. Original Article March 31, 2022 Full text PubReader ePub PDF	Prediction of Discharge Status and Readmissions after Resection of Intradural Spinal Tumors Michael C. Jin, Allen L. Ho, Austin Y. Feng, Zachary A. Medress, Arjun V. Pendharkar, Paymon Rezaii, John K. Ratliff, Atman M. Desai Neurospine. 2022;19(1):133-145. Original Article March 31, 2022 Full text PubReader ePub PDF Supplementary Material
Mechanical Failure After Total En Bloc Spondylectomy and Salvage Surgery Shin Won Kwon, Chun Kee Chung, Young Il Won, Woon Tak Yuh, Sung Bae Park, Seung Heon Yang, Chang Hyun Lee, John M. Rhee, Kyoung-Tae Kim, Chi Heon Kim Neurospine. 2022;19(1):146-154. Original Article March 31, 2022 Full text PubReader ePub PDF	Sacral Nerves Reconstruction After Surgical Resection of a Large Sacral Chordoma Restores the Urinary and Sexual Function and the Anal Continence Luigi Valentino Berra, Daniele Armocida, Mauro Palmieri, Valerio Di Norcia, Luca D’Angelo, Massimo Mongardini, Massimo Vigliotta, Edoardo Maccari, Antonio Santoro Neurospine. 2022;19(1):155-162. Technical Note January 30, 2022 Full text PubReader ePub PDF
Pearls and Pitfalls of Oblique Lateral Interbody Fusion: A Comprehensive Narrative Review Hyoungmin Kim, Bong-Soon Chang, Sam Yeol Chang Neurospine. 2022;19(1):163-176. Review Article March 31, 2022 Full text PubReader ePub PDF	Clinical Issues in Indication, Correction, and Outcomes of the Surgery for Neuromuscular Scoliosis: Narrative Review in Pedicle Screw Era Hak Sun Kim, Ji Won Kwon, Kun-Bo Park Neurospine. 2022;19(1):177-187. Review Article January 29, 2022 Full text PubReader ePub PDF
Location Distribution of Fistulas and Surgical Strategies for Spinal Extradural Meningeal Cysts: A Retrospective Analysis of 30 Cases at a Single Center Qiang Jian, Gang Song, Zhenlei Liu, Wanru Duan, Jian Guan, Fengzeng Jian, Zan Chen Neurospine. 2022;19(1):188-201. Original Article January 2, 2022 Full text PubReader ePub PDF	Reconstruction of the Cervical Lateral Mass Using 3-Dimensional-Printed Prostheses Qiang Jian, Zhenlei Liu, Wanru Duan, Jian Guan, Fengzeng Jian, Zan Chen Neurospine. 2022;19(1):202-211. Original Article February 2, 2022 Full text PubReader ePub PDF
Comparative Analysis of 3 Types of Minimally Invasive Posterior Cervical Foraminotomy for Foraminal Stenosis, Uniportal-, Biportal Endoscopy, and Microsurgery: Radiologic and Midterm Clinical Outcomes Ji Yeon Kim, Hyun Jin Hong, Dong Chan Lee, Tae Hyun Kim, Jin Seob Hwang, Choon Keun Park Neurospine. 2022;19(1):212-223. Original Article February 2, 2022 Full text PubReader ePub PDF	Risk Factors for Poor Outcomes Following Minimally Invasive Discectomy: A Post Hoc Subgroup Analysis of 2-Year Follow-up Prospective Data Zihao Chen, Lei He, Lijun Huang, Zhongyu Liu, Jianwen Dong, Bin Liu, Ruiqiang Chen, Liangming Zhang, Peigen Xie, Limin Rong Neurospine. 2022;19(1):224-235. Original Article March 31, 2022 Full text PubReader ePub PDF
The Last Touched Vertebra on Supine Radiographs Can Be the Optimal Lower Instrumented Vertebra in Adolescent Idiopathic Scoliosis Patients Do-Hyoung Kim, Seung-Jae Hyun, Chang-Hyun Lee, Ki-Jeong Kim Neurospine. 2022;19(1):236-243. Original Article March 31, 2022 Full text PubReader ePub PDF	The Impact of Spinal Cord Neuromodulation on Restoration of Walking Ability After Spinal Cord Injury Michael G. Fehlings, Alexander A. Velumian Neurospine. 2022;19(1):244-245. Editorial March 31, 2022 Full text PubReader ePub PDF
Scientific Achievements of Our Era: “Making the Lame Walk” Martin N. Stienen, Yoon Ha Neurospine. 2022;19(1):246-248. Editorial March 31, 2022 Full text PubReader ePub PDF