Objective Adult cervical deformity (ACD) is a debilitating spinal condition that causes significant pain, neurologic dysfunction, and functional impairment. Surgery is often performed to correct cervical alignment, but the optimal amount of correction required to improve patient-reported outcomes (PROs) are not yet well-defined.
Methods A review of the literature was performed and Fisher z-transformation (Zr) was used to pool the correlation coefficients between alignment parameters and PROs. The strength of correlation was defined according to the following: poor (0 < r ≤ 0.3), fair (0.3 < r ≤ 0.5), moderate (0.5 < r ≤ 0.8), and strong (0.8 < r ≤ 1).
Results Increased C2–7 sagittal vertical axis was fairly associated with increased Neck Disability Index (NDI) (pooled Zr = 0.31; 95% confidence interval [CI], -0.03 to 0.58). Changes in T1 slope minus cervical lordosis poorly correlated with NDI (pooled Zr = -0.04; 95% CI, -0.23 to 0.30). Increased C7–S1 was poorly associated with worse EuroQoL 5-Dimension (pooled Zr = -0.22; 95% CI, -0.36 to -0.06). Correction of horizontal gaze did not correlate with legacy metrics. Modified Japanese Orthopedic Association correlated with C2-slope, C7–S1, and C2–S1.
Conclusion Spinal alignment parameters variably correlated with improved health-related quality of life and myelopathy after corrective surgery for ACD. Further studies evaluating legacy PROs, Patient-Reported Outcomes Measurement System, and ACD specific instruments are needed for further validation.
Citations
Citations to this article as recorded by
Current Concepts of Sagittal Alignment in Adult Cervical Deformity Zeeshan M. Sardar, Justin L. Reyes, Josephine R. Coury, K. Daniel Riew Journal of the American Academy of Orthopaedic Surgeons.2026; 34(2): e176. CrossRef
Outcomes of Surgical Intervention of Dystrophic Cervical Kyphosis in Patients with Neurofibromatosis Type 1: A Systematic Review Dewa Gde Prema Ananda, Ida Bagus Sutha Dwipajaya, Ida Bagus Artha Vijaya Antara, Nia Irayati, Asra Al Fauzi Spine Surgery and Related Research.2026; 10(1): 11. CrossRef
Normative Cervical and Cervicothoracic Sagittal Alignment Parameters for Asymptomatic Adults: A Systematic Review and Meta-Analysis of >35,900 Participants Alexandra C. Dionne, Prakash Gorroochurn, Roy Miller, Prerana Katiyar, Samuel Bennion, Lisa Bonsignore-Opp, Josephine R. Coury, Fthimnir M. Hassan, Joseph M. Lombardi, Lawrence G. Lenke, Justin L. Reyes, Zeeshan M. Sardar Spine Open.2026;[Epub] CrossRef
Predictive value of preoperative T1 slope minus cervical lordosis for clinical outcomes after standalone laminectomy in elderly degenerative cervical myelopathy Ahmed Mohammed Ragab, Mahmoud M. Taha, Mansour Abdel Mageed Makkia, Ayman M. Ismail Scientific Reports.2026;[Epub] CrossRef
Neck and shoulder pain in thoracic adolescent idiopathic scoliosis 10 years after posterior spinal fusion Masayuki Ohashi, Kei Watanabe, Toru Hirano, Kazuhiro Hasegawa, Hideki Tashi, Tatsuo Makino, Keitaro Minato, Masayuki Sato, Hiroyuki Kawashima European Spine Journal.2024; 33(6): 2522. CrossRef
The Efficacy of Cervical Pedicle Screw Is Enhanced When Used With 5.5-mm Rods for Metastatic Cervical Spinal Tumor Surgery Danbi Park, Sang Hyub Lee, Subum Lee, Jemin Park, Hyeon Gyu Yang, Chongman Kim, Jin Hoon Park Neurospine.2024; 21(1): 352. CrossRef
Patient-specific implants and spinal alignment outcomes Renzo A. Laynes, Christopher J. Kleck North American Spine Society Journal (NASSJ).2024; 20: 100559. CrossRef
The Conceptualization and Derivation of the Cervical Lordosis Distribution Index Peter G. Passias, Tyler K. Williamson, Pooja Dave, Justin S. Smith, Oscar Krol, Renaud Lafage, Breton Line, Bassel G. Diebo, Alan H. Daniels, Eric O. Klineberg, Robert K. Eastlack, Shay Bess, Frank J. Schwab, Christopher I. Shaffrey, Virginie Lafage, Chri Spine.2024; 49(24): 1685. CrossRef
Radiographic Outcomes Following ACDF With Hyperlordotic Implants to Achieve Cervical Anterior Column Realignment Shane Shahrestani, Andy Ton, Nolan J. Brown, Zach Pennington, Joshua J. Loya, Cathleen Kuo, Yusuf Mehkri, Julian Gendreau, Luis Daniel Diaz-Aguilar, Martin H. Pham, Donald Blaskiewicz World Neurosurgery.2023; 174: e1. CrossRef
Cervical kinematic change after posterior full-endoscopic cervical foraminotomy for disc herniation or foraminal stenosis Seungyoon Paik, Yunhee Choi, Chun Kee Chung, Young Il Won, Sung Bae Park, Seung Heon Yang, Chang-Hyun Lee, John Min Rhee, Kyoung-Tae Kim, Chi Heon Kim, Thamer Hamdan PLOS ONE.2023; 18(2): e0281926. CrossRef
Concepts and Techniques to Prevent Cervical Spine Deformity After Spine Surgery: A Narrative Review Robert K. Merrill, John C. Clohisy, Todd J. Albert, Sheeraz A. Qureshi Neurospine.2023; 20(1): 221. CrossRef
L1-pelvic angle: a convenient measurement to attain optimal deformity correction Hani Chanbour, William Hunter Waddell, Justin Vickery, Matthew E. LaBarge, Andrew J. Croft, Michael Longo, Steven G. Roth, Jeffrey M. Hills, Amir M. Abtahi, Scott L. Zuckerman, Byron F. Stephens European Spine Journal.2023; 32(11): 4003. CrossRef
Relationship between TIA minus C0-7 angle and C2-7 SVA: analysis of 113 symptomatic patients Kai Yang, Xiang-Yu Li, Yu Wang, Chao Kong, Shi-Bao Lu BMC Musculoskeletal Disorders.2022;[Epub] CrossRef
Reciprocal Changes in the Whole-Body Following Realignment Surgery in Adult Spinal Deformity Jae-Koo Lee, Seung-Jae Hyun, Ki-Jeong Kim Asian Spine Journal.2022; 16(6): 958. CrossRef
Health risk assessment of groundwater nitrogen pollution in Yinchuan plain Bo Feng, Yuxue Ma, Yarong Qi, Yanxia Zhong, Xiaohua Sha Journal of Contaminant Hydrology.2022; : 104031. CrossRef
Do the newly proposed realignment targets for C2 and T1 slope bridge the gap between radiographic and clinical success in corrective surgery for adult cervical deformity? Lara Passfall, Tyler K. Williamson, Oscar Krol, Jordan Lebovic, Bailey Imbo, Rachel Joujon-Roche, Peter Tretiakov, Katerina Dangas, Stephane Owusu-Sarpong, Heiko Koller, Andrew J. Schoenfeld, Bassel G. Diebo, Shaleen Vira, Renaud Lafage, Virginie Lafage, Journal of Neurosurgery: Spine.2022; 37(3): 368. CrossRef
Odontoid Incidence: A Novel Cervical Parameter Influencing Cervical Alignment From Top to Bottom Jae-Koo Lee, Seung-Jae Hyun, Ki-Jeong Kim Neurospine.2022; 19(2): 463. CrossRef
Regional Anesthesia for Lumbar Spine Surgery: Can It Be a Standard in the Future? Jae-Koo Lee, Jong Hwa Park, Seung-Jae Hyun, Daniel Hodel, Oliver N. Hausmann Neurospine.2021; 18(4): 733. CrossRef
Polyetheretherketone vs Titanium Cages in Spinal Fusion: Spin Bias in Abstracts of Systematic Reviews and Meta-Analyses Henry Avetisian, Apurva Prasad, Kevin Mathew, David McCavitt, William J. Karakash, Dil Patel, Jeffrey C. Wang, Raymond J. Hah, Ram K. Alluri Global Spine Journal.2026; 16(1): 47. CrossRef
Titanium Cages versus Polyetheretherketone Cages in Interbody Fusions: A Meta-Analysis of Clinical and Radiographic Outcomes Mohammad Daher, Marven Aoun, Charbel Farhat, Gaby Kreichati, Khalil Kharrat, Alan H. Daniels, Amer Sebaaly World Neurosurgery.2025; 193: 15. CrossRef
Effect of cage surface geometry on load transfer and ranges of motion in a fused lumbar spine model: A comparative finite element analysis Tirtharaj Banerjee, Kishore Pradeep, Aritra Karar, Bidyut Pal Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine.2025; 239(5): 423. CrossRef
10-Year trend of lateral lumbar interbody fusion and the impact of 3D-printed titanium in a high-volume academic center Marco D. Burkhard, Ali E. Guven, Anna-Maria Mielke, Paul Köhli, Jan Hambrecht, Torben Stepan, Bruno Verna, Erika Chiapparelli, Jennifer Shue, Federico P. Girardi, Frank P. Cammisa, Andrew A. Sama, Alexander P. Hughes European Spine Journal.2025;[Epub] CrossRef
Clinical and radiological results of TLIF surgery with titanium-coated PEEK or uncoated PEEK cages: a prospective single-centre randomised study P. Vanek, N. Svoboda, O. Bradac, J. Malik, R. Kaiser, D. Netuka European Spine Journal.2024; 33(1): 332. CrossRef
Titanium-coated PEEK Versus Uncoated PEEK Cages in Lumbar Interbody Fusion Zheng-tao Lv, Yong Xu, Bin Cao, Jun Dai, Si-yuan Zhang, Jun-ming Huang, Shuang Liang, Feng-xian Jiang Clinical Spine Surgery.2023; 36(5): 198. CrossRef
Comparison of Long‐Term Outcomes between the n‐HA/PA66 Cage and the PEEK Cage Used in Transforaminal Lumbar Interbody Fusion for Lumbar Degenerative Disease: A Matched‐Pair Case Control Study Zhuang Zhang, Bo‐wen Hu, Liang Wang, Hui‐liang Yang, Tao Li, Li‐min Liu, Xi Yang, Yue‐ming Song Orthopaedic Surgery.2023; 15(1): 152. CrossRef
MRI-based Endplate Bone Quality score independently predicts cage subsidence following transforaminal lumbar interbody fusion Qian Chen, Youwei Ai, Yong Huang, Qiujiang Li, Juehan Wang, Hong Ding, Ce Zhu, Ganjun Feng, Limin Liu The Spine Journal.2023; 23(11): 1652. CrossRef
Biomedical Applications of Titanium Alloys: A Comprehensive Review Elia Marin, Alex Lanzutti Materials.2023; 17(1): 114. CrossRef
Development of a decision-making pathway for utilizing standalone lateral lumbar interbody fusion Dominik Adl Amini, Manuel Moser, Lisa Oezel, Jiaqi Zhu, Jennifer Shue, Andrew A. Sama, Frank P. Cammisa, Federico P. Girardi, Alexander P. Hughes European Spine Journal.2022; 31(7): 1611. CrossRef
Biomechanical analysis of stand-alone lumbar interbody cages versus 360° constructs: an in vitro and finite element investigation Ali Kiapour, Elie Massaad, Amin Joukar, Muhamed Hadzipasic, Ganesh M. Shankar, Vijay K. Goel, John H. Shin Journal of Neurosurgery: Spine.2022; 36(6): 928. CrossRef
Evaluation of cage subsidence in standalone lateral lumbar interbody fusion: novel 3D-printed titanium versus polyetheretherketone (PEEK) cage Dominik Adl Amini, Ichiro Okano, Lisa Oezel, Jiaqi Zhu, Erika Chiapparelli, Jennifer Shue, Andrew A. Sama, Frank P. Cammisa, Federico P. Girardi, Alexander P. Hughes European Spine Journal.2021; 30(8): 2377. CrossRef
Objective Lumbar fusion with implantation of interbody cage is a common procedure for treatment of lumbar degenerative disease. This study aims to compare the fusion and subsidence rates of titanium (Ti) versus polyetheretherketone (PEEK) interbody cages after posterior lumbar interbody fusion and investigate the effect of clinical and radiological outcomes following fusion on patient-reported outcomes.
Methods A systematic search strategy of 4 electronic databases (MEDLINE, Embase, Web of Science, and Cochrane) was conducted using different MeSH (medical subject headings) terms until January 2020. Pooled odds ratios (ORs) with 95% confidence intervals (CI) were calculated using fixed and random-effect models based upon the heterogeneity (I2) to estimate the association between interbody cages and the measured outcomes.
Results A total of 1,094 patients from 11 studies were reviewed. The final analysis included 421 patients (38.5%) who had lumbar surgery using a Ti and/or a Ti-coated interbody cage and 673 patient (61.5%) who had lumbar surgery using a PEEK cage. Overall, PEEK interbody devices were associated with a significantly lower fusion rate compared with Ti interbody devices (OR, 0.62; 95% CI, 0.41–0.93; p = 0.02). There was no difference in subsidence rates between Ti and PEEK groups (OR, 0.91; 95% CI, 0.54–1.52; p = 0.71). Also, there were no statistically significant differences in visual analogue scale (VAS)-low back pain (p = 0.14) and Japanese Orthopedic Association scale (p = 0.86) between the 2 groups. However, the PEEK group had lower odds of leg pain after surgery compared to the Ti group (OR [VAS-leg], 0.61; 95% CI, 0.28–0.94; p = 0.003).
Conclusion Ti and Ti-coated PEEK cages used for posterior lumbar interbody fusion are associated with similar rates of subsidence, but a higher rate of fusion compared to PEEK interbody cages. Randomized controlled trials are needed to better assess the effect of cage materials and potential factors that could influence the outcomes of interbody lumbar fusion.
Citations
Citations to this article as recorded by
Evaluation of three methods of coaxial endoscopic lumbar fusion for treating lumbar degenerative diseases: a retrospective cohort study Wenbo Diao, Xueya Feng, Yuanli Li, Jian Gao, Haoran Chen, Qianchun Li Neurosurgical Review.2026;[Epub] CrossRef
Unilateral Biportal Endoscopic Transforaminal Lumbar Interbody Fusion (TLIF) Using 3-Dimensional-Printed Titanium Cages Compared With Open TLIF: A Comparison of Clinical Outcomes and Fusion Rates Sang Hyub Lee, Junghan Seo, Dain Jeong, Sang Youp Han, Dong Hyun Lee, Jae-Won Jang, Dong-Geun Lee, Choon Keun Park Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(Suppl 1): S28. CrossRef
Osteointegration and Fusion After TLIF: Trabecular Titanium Cage with SVF-Hydrogel Compared with PEEK Cage. Murat U. Baidarbekov, Zhangir N. Ipmagambetov, Nailya DeLellis, Olzhas S. Bekarissov, Margulan S. Abdikalikov, Daniyar Zh. Yestay Orthopedic Reviews.2026;[Epub] CrossRef
Reduced Subsidence With PEEK-Titanium Composite Versus 3D Titanium Cages in a Retrospective, Self-Controlled Study in Transforaminal Lumbar Interbody Fusion Ali Chahlavi Global Spine Journal.2025; 15(3): 1598. CrossRef
A comprehensive review on the State of the Art in the research and development of poly-ether-ether-ketone (PEEK) biomaterial-based implants Prabaha Sikder Acta Biomaterialia.2025; 191: 29. CrossRef
3D printed titanium banana interbody cages versus titanium-coated PEEK bullet cages for TLIF Connor C. Jacob, Ryan Eaton, Jacob Ward, Katelyn Sette, Seth Wilson, Matthieu D. Weber, Olivia Duru, Alexander Keister, Markus E. Harrigan, Andrew J. Grossbach, Stephanus Viljoen Clinical Neurology and Neurosurgery.2025; 249: 108731. CrossRef
Verification of the Cage Stability and the Superiority of Titanium Coating in the Bone Fusion of Transforaminal Lumbar Interbody Fusion Using Polyetheretherketone Cages Kazutaka Masamoto, Shimei Tanida, Bungo Otsuki, Shunsuke Fujibayashi Cureus.2025;[Epub] CrossRef
Evaluation of Healthcare Outcomes of Patients Treated with 3D-Printed-Titanium and PEEK Cages During Fusion Procedures in the Lumbar Spine Katherine Corso, Andreas Teferra, Annalisa Michielli, Kristin Corrado, Amy Marcini, Mark Lotito, Caroline Smith, Michelle Costa, Jill Ruppenkamp, Anna Wallace Medical Devices: Evidence and Research.2025; Volume 18: 37. CrossRef
Radiographic and Clinical Comparison of Polyetheretherketone Versus 3D-Printed Titanium Cages in Lumbar Interbody Fusion—A Single Institution’s Experience Diang Liu, Julie L. Chan, Art Eleanore, Kristin DeCost, Justin Luk, Lissette C. Neukam, Tasneem Zaihra Rizvi, Zhibang Lin, Zoher Ghogawala, Subu N. Magge, Andrew Y. Yew, Robert G. Whitmore Journal of Clinical Medicine.2025; 14(6): 1813. CrossRef
Expandable cage technology in minimally invasive transforaminal interbody fusion: where are we and what does the future hold? Chibuikem A. Ikwuegbuenyi, Noah Willett, Evan Wang, Sean Inzerillo, Ibrahim Hussain Expert Review of Medical Devices.2025; 22(4): 349. CrossRef
Clinical and radiological outcomes of titanium cage versus polyetheretherketone cage in lumbar interbody fusion: a systematic review and meta-analysis Haozhong Wang, Hao Zhang, Changming Xiao, Kaiquan Zhang, Lisheng Qi Neurosurgical Review.2025;[Epub] CrossRef
Understanding the influence of cage and instrumentation strategies with oblique lumbar interbody fusion for grade I spondylolisthesis – A comprehensive biomechanical modeling study Mathieu Chayer, Philippe Phan, Pierre-Jean Arnoux, Zhi Wang, Jeremy J. Rawlinson, Olumide Aruwajoye, Carl-Éric Aubin The Spine Journal.2025; 25(10): 2312. CrossRef
Impact of Cage Material (PEEK vs. Titanium) on Subsidence, Fusion, and Patient-reported Outcomes After Transforaminal Lumbar Interbody Fusion Forrest Hamrick, Robert B. Kim, Andrew T. Dailey, Erica F. Bisson, Mark A. Mahan, Marcus D. Mazur Clinical Spine Surgery.2025;[Epub] CrossRef
Preclinical evaluation of lateral interbody fusions using 3D printed PEEK or 3D printed titanium cages William Robert Walsh, Matthew Pelletier, Dan Wills, Tian Wang, Max Lloyd, Michael Veldman, Nick Cordaro, Mark Brady North American Spine Society Journal (NASSJ).2025; 23: 100756. CrossRef
‘Rebound Phenomenon’ – a Cause of Early Cage Back-out in Transforaminal Lumbar Interbody Fusion Surgery: Insights from Case Series of 1545 Patients Jvahar Jill, Sathish Muthu, Guna Pratheep Kalanchiam, Nalli Ramanathan Uvaraj Indian Journal of Orthopaedics.2025; 59(12): 2126. CrossRef
Application of Biocomposite Hydrogel With Developed Trabecular Cage in Lumbar Interbody Fusion: A Clinical Case Report Murat U. Baidarbekov, Olzhas S. Bekarisov, Zhangir N. Ipmagambetov, Margulan S. Abdigalikov, Agzam A. Akimbekov Clinical Medicine Insights: Case Reports.2025;[Epub] CrossRef
Unilateral biportal endoscopy for minimally invasive spinal fusion: Advancements in biomaterials and clinical outcome optimization Song Fu, Li-Chuan Hou, Xiao-Ling Huang, Wei Zhao, Feng-Ming Wang, Ya-Nan Wang World Journal of Orthopedics.2025;[Epub] CrossRef
Development and Validation of Interpretable Machine Learning Models Incorporating Paraspinal Muscle Quality to Predict Cage Subsidence Risk Following Posterior Lumbar Interbody Fusion Haifu Sun, Wenxiang Tang, Lei Deng, Xingyu You, Zhairui Shen, Xiao Sun, Jun Zou, Fanguo Lin, Zhonglai Qian, Huilin Yang, Hao Liu Spine.2025; 50(20): 1375. CrossRef
Analysis of the anti-subsidence mechanical properties of novel 3D-printed titanium cages compared to conventional titanium cages Huiming Yang, Yuhang Wang, Junxian Miao, Jiangtao Wang, Hao Li, Yang Zhang, Liang Yan, Biao Wang Journal of Orthopaedic Surgery and Research.2025;[Epub] CrossRef
Advances in Titanium-Based Biomaterial for Human Bone Scaffolds: Narrative Review on Design, Fabrication, Surface Engineering, Implantation, and Biological Evaluation Sichale W. Fita, Mirosław Bonek, Anna Woźniak, Sebastian Sławski Materials.2025; 18(23): 5421. CrossRef
Analysis of Clinical Indicators of Surgical Treatment of Degenerative Spinal Diseases Operated with Posterior Access Using the PEEK Cage Murat Umirkhanovich Baidarbekov, Olzhas Sapargalievich Bekarissov, Zhangir Narimanovich Ipmagambetov, Alexandr Yuryevich Chsherbina, Margulan Serikbayevich Abdikalikov, Rinat Akhmetrizovich Chekaev, Kaldygul Musaevna Yeldashbaeva West Kazakhstan Medical Journal.2025; 67(4): 410. CrossRef
Clinical and radiological results of TLIF surgery with titanium-coated PEEK or uncoated PEEK cages: a prospective single-centre randomised study P. Vanek, N. Svoboda, O. Bradac, J. Malik, R. Kaiser, D. Netuka European Spine Journal.2024; 33(1): 332. CrossRef
Feasibility analysis of wireless power delivery to implanted sensors of XLIF patients Subhas C. Mukhopadhyay, Isaac Senn, Vivek Ramakrishna, Boby George, Gangadhara Prusty, Ashish Diwan International Journal on Smart Sensing and Intelligent Systems.2024;[Epub] CrossRef
3D-printed porous titanium versus polyetheretherketone cages in lateral lumbar interbody fusion: a systematic review and meta-analysis of subsidence Shu-Xin Liu, Teng-Hui Zeng, Chien-Min Chen, Li-Ru He, An-Ping Feng, Shang-Wun Jhang, Guang-Xun Lin Frontiers in Medicine.2024;[Epub] CrossRef
Outcome of Ti/PEEK Versus PEEK Cages in Minimally Invasive Transforaminal Lumbar Interbody Fusion Yu-Cheng Yao, Po-Hsin Chou, Hsi-Hsien Lin, Shih-Tien Wang, Ming-Chau Chang Global Spine Journal.2023; 13(2): 472. CrossRef
A novel injectable hydrogel containing polyetheretherketone for bone regeneration in the craniofacial region Mahdieh Alipour, Marjan Ghorbani, Masume Johari khatoonabad, Marziyeh Aghazadeh Scientific Reports.2023;[Epub] CrossRef
Near-Surface Nanomechanics of Medical-Grade PEEK Measured by Atomic Force Microscopy Marco Bontempi, Rosario Capozza, Andrea Visani, Milena Fini, Gianluca Giavaresi, Alessandro Gambardella Polymers.2023; 15(3): 718. CrossRef
Effect of Interbody Implants on the Biomechanical Behavior of Lateral Lumbar Interbody Fusion: A Finite Element Study Hangkai Shen, Jia Zhu, Chenhui Huang, Dingding Xiang, Weiqiang Liu Journal of Functional Biomaterials.2023; 14(2): 113. CrossRef
Titanium‑coated polyetheretherketone cages vs. polyetheretherketone cages in lumbar interbody fusion: A systematic review and meta‑analysis Songfeng Li, Xiyong Li, Xiaohui Bai, Yunlu Wang, Pengfei Han, Hongzhuo Li Experimental and Therapeutic Medicine.2023;[Epub] CrossRef
Three-Dimensional-Printed Titanium Versus Polyetheretherketone Cages for Lumbar Interbody Fusion: A Systematic Review of Comparative In Vitro, Animal, and Human Studies Neal A. Patel, Sinead O’Bryant, Christopher D. Rogers, Candler K. Boyett, Sachiv Chakravarti, Julian Gendreau, Nolan J. Brown, Zach A. Pennington, Neill B. Hatcher, Cathleen Kuo, Luis Daniel Diaz-Aguilar, Martin H. Pham Neurospine.2023; 20(2): 451. CrossRef
Response to the letter to the editor regarding “Vertebral bone quality score independently predicts cage subsidence following transforaminal lumbar interbody fusion” Mohamed A.R. Soliman, Alexander O. Aguirre, Cathleen C. Kuo, Rehman Ali Baig, Asham Khan, Jeffrey P. Mullin, John Pollina The Spine Journal.2023; 23(8): 1239. CrossRef
Development and validation of a risk prediction model for cage subsidence after instrumented posterior lumbar fusion based on machine learning: a retrospective observational cohort study Tuotuo Xiong, Ben Wang, Wanyuan Qin, Ling Yang, Yunsheng Ou Frontiers in Medicine.2023;[Epub] CrossRef
Feasibility of Non-window Three-Dimensional–Printed Porous Titanium Cage in Posterior Lumbar Interbody Fusion: A Pilot Trial Dae-Woong Ham, Chan-Woo Jung, Dong-Gune Chang, Jae Jun Yang, Kwang-Sup Song Clinics in Orthopedic Surgery.2023; 15(6): 960. CrossRef
Morphometric Comparison of Interbody Fusion with Cage and Autograft at L4-L5 Levels versus Autograft Alone for Fusion Azmi Tufan, Feyza Karagöz Güzey, Abdurrahman Aycan Bagcilar Medical Bulletin.2023; 8(3): 293. CrossRef
Relationship between the elastic modulus of the cage material and the biomechanical properties of transforaminal lumbar interbody fusion: A logarithmic regression analysis based on parametric finite element simulations Teng Lu, Jiakun Ren, Zhongwei Sun, Jing Zhang, Kai Xu, Lu Sun, Pinglin Yang, Dong Wang, Yueyun Lian, Jingjing Zhai, Yali Gou, Yanbing Ma, Shengfeng Ji, Xijing He, Baohui Yang Computer Methods and Programs in Biomedicine.2022; 214: 106570. CrossRef
3D-printed titanium cages without bone graft outperform PEEK cages with autograft in an animal model Joseph L. Laratta, Bradley J. Vivace, Mónica López-Peña, Fernando Muñoz Guzón, Antonio Gonzalez-Cantalpeidra, Alberto Jorge-Mora, Rosa Maria Villar-Liste, Laura Pino-Lopez, Alexandr Lukyanchuk, Erik Arden Taghizadeh, Jesús Pino-Minguez The Spine Journal.2022; 22(6): 1016. CrossRef
Comparative Study of Cage Subsidence in Single-Level Lateral Lumbar Interbody Fusion Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Satoshi Nomura, Masato Sato, Masahiko Watanabe Journal of Clinical Medicine.2022; 11(5): 1374. CrossRef
A Review of Biomimetic Topographies and Their Role in Promoting Bone Formation and Osseointegration: Implications for Clinical Use Michael B. Berger, Paul Slosar, Zvi Schwartz, David J. Cohen, Stuart B. Goodman, Paul A. Anderson, Barbara D. Boyan Biomimetics.2022; 7(2): 46. CrossRef
Choice of Spinal Interbody Fusion Cage Material and Design Influences Subsidence and Osseointegration Performance Guy Fogel, Nicholas Martin, Gregory M. Williams, Jesse Unger, Christian Yee-Yanagishita, Matthew Pelletier, William Walsh, Yun Peng, Michael Jekir World Neurosurgery.2022; 162: e626. CrossRef
Approaches to Biofunctionalize Polyetheretherketone for Antibacterial: A Review Yihan Wang, Shutao Zhang, Bin’en Nie, Xinhua Qu, Bing Yue Frontiers in Bioengineering and Biotechnology.2022;[Epub] CrossRef
Evolution of polyetheretherketone (PEEK) and titanium interbody devices for spinal procedures: a comprehensive review of the literature Nallammai Muthiah, Yagiz Ugur Yolcu, Nima Alan, Nitin Agarwal, David Kojo Hamilton, Alp Ozpinar European Spine Journal.2022; 31(10): 2547. CrossRef
Biodegradable interbody cages for lumbar spine fusion: Current concepts and future directions Markus Laubach, Philipp Kobbe, Dietmar W. Hutmacher Biomaterials.2022; 288: 121699. CrossRef
Vertebral bone quality score independently predicts cage subsidence following transforaminal lumbar interbody fusion Mohamed A.R. Soliman, Alexander O. Aguirre, Cathleen C. Kuo, Nicco Ruggiero, Shady Azmy, Asham Khan, Moleca M. Ghannam, Neil D. Almeida, Patrick K. Jowdy, Jeffrey P. Mullin, John Pollina The Spine Journal.2022; 22(12): 2017. CrossRef
A Comparison of Polyetheretherketone and Titanium-Coated Polyetheretherketone in Minimally Invasive Transforaminal Lumbar Interbody Fusion: A Randomized Clinical Trial Weerasak Singhatanadgige, Nattapat Tangchitcharoen, Stephen J. Kerr, Teerachat Tanasansomboon, Wicharn Yingsakmongkol, Vit Kotheeranurak, Worawat Limthongkul World Neurosurgery.2022; 168: e471. CrossRef
Complications in Spinal Fusion Surgery: A Systematic Review of Clinically Used Cages Francesca Veronesi, Maria Sartori, Cristiana Griffoni, Marcelo Valacco, Giuseppe Tedesco, Paolo Francesco Davassi, Alessandro Gasbarrini, Milena Fini, Giovanni Barbanti Brodano Journal of Clinical Medicine.2022; 11(21): 6279. CrossRef
Biomechanical comparison of subsidence performance among three modern porous lateral cage designs Christian Yee-Yanagishita, Guy Fogel, Brooke Douglas, Gregory Essayan, Brijesh Poojary, Nicholas Martin, Gregory M. Williams, Yun Peng, Michael Jekir Clinical Biomechanics.2022; 99: 105764. CrossRef
An alternative method to evaluate lumbar interbody fusion status focusing on position change of screw-rod constructs Atsushi Yamamoto, Satoru Tanioka, Masashi Fujimoto, Hirofumi Nishikawa, Yusuke Kamei, Munenari Ikezawa, Fujimaro Ishida, Takahiro Miyazaki, Hidenori Suzuki, Masaki Mizuno European Radiology.2022; 33(3): 1545. CrossRef
Surgical outcome of minimal invasive oblique lateral interbody fusion with percutaneous pedicle screw fixation in the treatment of adult degenerative scoliosis Jun Seok Lee, Dong Wuk Son, Su Hun Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song, Young Ha Kim, Chang Hwa Choi Medicine.2022; 101(48): e31879. CrossRef
Superior Osteo-Inductive and Osteo-Conductive Properties of Trabecular Titanium vs. PEEK Scaffolds on Human Mesenchymal Stem Cells: A Proof of Concept for the Use of Fusion Cages Enrico Ragni, Carlotta Perucca Orfei, Alessandro Bidossi, Elena De Vecchi, Natale Francaviglia, Alberto Romano, Gianluca Maestretti, Fulvio Tartara, Laura de Girolamo International Journal of Molecular Sciences.2021; 22(5): 2379. CrossRef
Comparison of MRI Visualization Following Minimally Invasive and Open TLIF: A Retrospective Single-Center Study Vadim A. Byvaltsev, Andrei A. Kalinin, Morgan B. Giers, Valerii V. Shepelev, Yurii Ya. Pestryakov, Mikhail Yu. Biryuchkov Diagnostics.2021; 11(5): 906. CrossRef
Polyetheretherketone for orthopedic applications: a review Yi-Hsun Yu, Shih-Jung Liu Current Opinion in Chemical Engineering.2021; 32: 100687. CrossRef
A Prospective, Multi-Center, Double-Blind, Randomized Study to Evaluate the Efficacy and Safety of the Synthetic Bone Graft Material DBM Gel with rhBMP-2 versus DBM Gel Used during the TLIF Procedure in Patients with Lumbar Disc Disease Seung-Jae Hyun, Seung Hwan Yoon, Joo Han Kim, Jae Keun Oh, Chang-Hyun Lee, Jun Jae Shin, Jiin Kang, Yoon Ha Journal of Korean Neurosurgical Society.2021; 64(4): 562. CrossRef
Anterior Bridging Bone in a Newly Designed Cage for Lumbar Interbody Fusion: Radiographic and Finite Element Analysis Jeongik Lee, Seung-Hwan Chang, Hyung-Chul Cho, Kwang-Sup Song World Neurosurgery.2021; 154: e389. CrossRef
PEEK Versus Titanium Static Interbody Cages Jose A. Canseco, Brian A. Karamian, Parthik D. Patel, Srikanth N. Divi, Tyler Timmons, Haydn Hallman, Ryan Nachwalter, Joseph K. Lee, Mark F. Kurd, D. Greg Anderson, Jeffrey A. Rihn, Alan S. Hilibrand, Christopher K. Kepler, Alexander R. Vaccaro, Gregory Clinical Spine Surgery.2021; 34(8): E483. CrossRef
Efficacy for Whitlockite for Augmenting Spinal Fusion Su Yeon Kwon, Jung Hee Shim, Yu Ha Kim, Chang Su Lim, Seong Bae An, Inbo Han International Journal of Molecular Sciences.2021; 22(23): 12875. CrossRef
Polyetheretherketone and Its Composites for Bone Replacement and Regeneration Chengzhu Liao, Yuchao Li, Sie Chin Tjong Polymers.2020; 12(12): 2858. CrossRef
PEEK versus titanium cages in lateral lumbar interbody fusion: a comparative analysis of subsidence Peter G. Campbell, David A. Cavanaugh, Pierce Nunley, Philip A. Utter, Eubulus Kerr, Rishi Wadhwa, Marcus Stone Neurosurgical Focus.2020; 49(3): E10. CrossRef
First
Prev
