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"Biswadjiet S. Harhangi"

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Minimally Invasive Spinal Surgery SMISS-Neurospine Special Issue

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Surgeons Learning Curve of Transforaminal Endoscopic Discectomy for Sciatica
Neurospine. 2022;19(3):594-602.   Published online September 30, 2022
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Surgeons Learning Curve of Transforaminal Endoscopic Discectomy for Sciatica
Neurospine. 2022;19(3):594-602.   Published online September 30, 2022
Close
Objective
Full-endoscopic spine surgery is gaining interest as a less-invasive alternative to treat sciatica caused by a lumbar disc herniation. Concerns, however, exist with the learning curve as percutaneous transforaminal endoscopic discectomy (PTED) appears to be more difficult to be performed compared to other techniques. In this study, the clinical outcomes during and after the learning curve are presented of 3 surgeons naïve to PTED.
Methods
In the first phase of a randomized controlled, noninferiority trial comparing PTED with microdiscectomy, 3 surgeons were trained in the PTED-procedure by a senior surgeon. After performing up to 20 cases under supervision, they started performing PTED on their own. Results of the early cases were compared to the later cases (>20). Furthermore, complications and reoperations were compared. Finally, differences in clinical outcomes between surgeons were compared.
Results
At 12 months of follow-up, 87% of the patients had follow-up data available. In general, there were no significant differences in patient-reported outcomes between the early and later PTED cases. Furthermore, outcomes of the early PTED cases were comparable to the outcomes of microdiscectomy, while the later PTED cases had small, but more favorable outcomes compared to microdiscectomy. Two learning curve surgeons had substantially higher rates of reoperations within 1 year, compared to the senior surgeon or the microdiscectomy group. Duration of surgery was also longer for all learning curve surgeons. Finally, when comparing clinical outcomes of patients undergoing PTED versus microdiscectomy, there appears to be some statistically significant differences in outcomes compared between the senior and 3 learning curve surgeons.
Conclusion
PTED appears to be safe to be adopted by surgeons naïve to the procedure when they are initially supervised by an experienced senior surgeon. Duration of surgery and risk of repeated surgery are increased during the learning curve, but patient-reported outcomes of the early PTED cases are similar to the outcomes of later PTED cases, and similar to the outcomes of microdiscectomy cases. This study underlines the need for an experienced mentor for surgeons to safely adopt PTED.

Citations

Citations to this article as recorded by  Crossref logo
  • The Initial Learning and Supply Cost Curve of Incorporating Interlaminar and Transforaminal Endoscopy at a Tertiary Academic Medical Center
    Mark M Zaki, Edward S Harake, Varun G Kathawate, Michael J Strong, Rushikesh S Joshi, Joseph R Linzey, Yamaan S Saadeh, Osama N Kashlan
    Cureus.2026;[Epub]     CrossRef
  • Operative time, recurrence, and complications throughout the initial learning curve in transforaminal endoscopic lumbar discectomy
    Michelle D. Poelman, Annegien Boeykens, Biswadjiet S. Harhangi, Marc L. Schröder, Victor E. Staartjes
    Acta Neurochirurgica.2026;[Epub]     CrossRef
  • Endoscopic Spine Surgery: A Scoping Review of the Literature
    Drew Mulhall, Chien Yew Kow, Catherine Veilleux, Anand Oliveira Masson, Steven Casha, Stephan du Plessis, Ken Thomas, Michael M. H. Yang
    Global Spine Journal.2026;[Epub]     CrossRef
  • Simulation training in spinal endoscopic surgery: a systematic review of current status
    Gilberto Perez Rodriguez Garcia, Abdulwhab Alotaibi, Omid Yousefi, Ataollah Shahbandi, Pegah Ghamasaee, Abdul Mounnem Yassin Kassab, Rakan Bokhari, Muhammad Abd-El-Barr, Saman Shabani, Mohamad Bakhaidar
    Neurosurgical Review.2026;[Epub]     CrossRef
  • Percutaneous Endoscopic Debridement and Drainage for Infectious Spondylodiscitis Under Local Anesthesia
    Ji-Ho Jung, Jong-Hoon Jeong, Jong-Hwan Hong, Moon-Soo Han, Jung-Kil Lee
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(1): 163.     CrossRef
  • Meta-Analysis of Learning Curve in Endoscopic Spinal Surgery: Impact on Surgical Outcomes
    Juan Álvarez de Mon-Montoliú, Juan Castro-Toral, César Bonome-González, Manuel González-Murillo
    Global Spine Journal.2025; 15(4): 2500.     CrossRef
  • Classification of endoscopic spine procedures
    Mazda Farshad, Christoph J. Laux, Florian Wanivenhaus, José M. Spirig, Jonas Widmer, Michael Kelly, Javier Quillo-Olvera, Jin-Sung Kim, Facundo van Isseldyk, Sohrab Gollogly, James Yue, Xuexiao Ma, Vincent Hagel, Frédéric Cornaz
    North American Spine Society Journal (NASSJ).2025; 22: 100603.     CrossRef
  • Large-Channel Interlaminar Endoscopic Discectomy for Highly Migrated Lumbar Disc Herniation: Effectiveness and Safety
    Shicheng Zheng, Qinghua Zhao, Zongshan Hu, Haibo Li, Bin Wang, Zezhang Zhu, Yong Qiu, Xu Sun
    Journal of Pain Research.2025; Volume 18: 3821.     CrossRef
  • Rediscovering Posterior Cervical Foraminotomy/Diskectomy With the Endoscope: A Favorable Cost Comparison with the Traditional Treatment of a Cervical Radiculopathy
    Campbell Liles, Hani Chanbour, Alexander T. Lyons, Emma Ye, Omar Zakieh, Robert J. Dambrino, Iyan Younus, Soren Jonzzon, Richard A. Berkman, Julian G. Lugo-Pico, Amir M. Abtahi, Byron F. Stephens, Scott L. Zuckerman, Raymond J. Gardocki
    Operative Neurosurgery.2025;[Epub]     CrossRef
  • Three-dimensional virtual surgical planning enhances precision and safety in percutaneous transforaminal endoscopic discectomy: a retrospective comparative study
    Yang Fuguo, Chen Kang, Luo Yuanchao, He Renjian
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Outcome of Percutaneous Endoscopic Lumbar Discectomy in Relation to the Surgeon’s Experience: Propensity Score Matching
    Seong Son, Michael Y. Oh, Han Byeol Park, Alexander M. Lopez
    Bioengineering.2024; 11(4): 312.     CrossRef
  • Comparison of Clinical and Radiographic Outcomes Between Transforaminal Endoscopic Lumbar Discectomy and Microdiscectomy: A Follow-up Exceeding 5 Years
    Xinyu Yang, Shijun Zhang, Junxiao Su, Sai Guo, Yakubu Ibrahim, Kai Zhang, Yonghao Tian, Lianlei Wang, Suomao Yuan, Xinyu Liu
    Neurospine.2024; 21(1): 303.     CrossRef
  • Percutaneous endoscopic transforaminal discectomy and unilateral biportal endoscopic discectomy for lumbar disc herniation: a comparative analysis of learning curves
    Zhangfu Li, Honghao Yang, Yaoshen Zhang, Chaofan Han, Yuzeng Liu, Li Guan, Jincai Yang, Yong Hai, Aixing Pan
    European Spine Journal.2024; 33(6): 2154.     CrossRef
  • Learning curve analyses in spine surgery: a systematic simulation-based critique of methodologies
    Conor McNamee, Salman Keraidi, Jake McDonnell, Andrew Kelly, Julia Wall, Stacey Darwish, Joseph S. Butler
    The Spine Journal.2024; 24(10): 1789.     CrossRef
  • Is Close Supervision by a Senior Surgeon Necessary During the Initial Days of Performing Endoscopic Lumbar Discectomy? A Retrospective Comparative Study between Two Fellowship Trained Surgeons to Assess the Learning Curve
    Syed Ifthekar, Shih-Min Lee, Sang-Ho Lee, Sang-Ha Shin, Junseok Bae
    Journal of West African College of Surgeons.2024;[Epub]     CrossRef
  • The evolution and integration of technology in spinal neurosurgery: A scoping review
    Moksada Regmi, Weihai Liu, Shikun Liu, Yuwei Dai, Ying Xiong, Jun Yang, Chenlong Yang
    Journal of Clinical Neuroscience.2024; 129: 110853.     CrossRef
  • Is minimally invasive surgery a game changer in spinal surgery?
    Sang-Min Park, Ho-Joong Kim, Jin S. Yeom
    Asian Spine Journal.2024; 18(5): 743.     CrossRef
  • Evolving Paradigms in Spinal Surgery: A Systematic Review of the Learning Curves in Minimally Invasive Spine Techniques
    Kun Wu, Zhihe Yun, Siravich Suvithayasiri, Yihao Liang, Dimas Rahman Setiawan, Vit Kotheeranurak, Khanathip Jitpakdee, Enrico Giordan, Qinyi Liu, Jin-Sung Kim
    Neurospine.2024; 21(4): 1251.     CrossRef
  • Reply to letter to the editor regarding, “Biportal endoscopic versus microscopic discectomy for lumbar herniated disc: a randomized controlled trial”
    Sang-Min Park, Ho-Joong Kim
    The Spine Journal.2023; 23(3): 469.     CrossRef
  • Letter to the editor regarding, “Biportal endoscopic versus microscopic discectomy for lumbar herniated disc: A randomized controlled trial” by Park et al. Concepts, analyses and interpretation of noninferiority randomized controlled trials
    Pravesh S. Gadjradj, Fabian Sommer, Rodrigo Navarro-Ramirez, Judith D. de Rooij
    The Spine Journal.2023; 23(3): 467.     CrossRef
  • Initial learning curve after switching to uniportal endoscopic discectomy for lumbar disc herniations
    Catherine Olinger, Alex Coffman, Chad Campion, Kirk Thompson, Raymond Gardocki
    European Spine Journal.2023; 32(8): 2694.     CrossRef
  • Training to be a spinal endoscopic surgeon: What matters?
    Yizhou Xie, Qun Zhou, Yongtao Wang, Chengzhi Feng, Xiaohong Fan, Yang Yu
    Frontiers in Surgery.2023;[Epub]     CrossRef
  • Why Endoscopic Spine Surgery?
    Woo-Keun Kwon, Se-Hoon Kim
    Neurospine.2023; 20(1): 7.     CrossRef
  • Commentary on “Complications and Management of Endoscopic Spinal Surgery”
    Hyeun-Sung Kim, Pang Hung Wu, Il-Tae Jang
    Neurospine.2023; 20(1): 78.     CrossRef
  • Full endoscopic spine surgery
    Pramod V. Lokhande
    Journal of Orthopaedics.2023; 40: 74.     CrossRef
  • The Role and Clinical Outcomes of Endoscopic Spine Surgery of Treating Spinal Metastases; Outcomes of 29 Cases From 8 Countries
    Siravich Suvithayasiri, Young-Jin Kim, Yanting Liu, Warayos Trathitephun, Akarawit Asawasaksaku, Javier Quillo-Olvera, Vit Kotheeranurak, Haroldo Chagas, Cristian Correa Valencia, Marcus Vinicius Serra, Facundo Van Isseldyk, Lung-Hsing Lee, Chien-Min Chen
    Neurospine.2023; 20(2): 608.     CrossRef
  • 8,602 View
  • 250 Download
  • 24 Web of Science
  • 26 Crossref

Minimally Invasive Spinal Surgery SMISS-Neurospine Special Issue

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Assessing the Learning Process of Transforaminal Endoscopic Discectomy for Sciatica
Neurospine. 2022;19(3):563-570.   Published online September 30, 2022
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Assessing the Learning Process of Transforaminal Endoscopic Discectomy for Sciatica
Neurospine. 2022;19(3):563-570.   Published online September 30, 2022
Close
Objective
Percutaneous transforaminal endoscopic discectomy (PTED) is gaining popularity by both surgeons and patients as a less invasive treatment option for sciatica. Concerns, however, exist for its learning curve. No previous study has assessed the learning process of PTED. Hereby we present the learning process of 3 surgeons learning PTED.
Methods
This analysis was conducted alongside a multicenter randomized controlled trial. After attending a cadaveric workshop, 3 spine-dedicated surgeons started performing PTED, initially under the supervision of a senior surgeon. After each 5 cases, and up to case 20, the learning process was evaluated using the validated questionnaires (objective structured assessment of technical skills [OSATS], global operative assessment of laparoscopic skills [GOALS]) and a 10-step checklist specifically developed for PTED.
Results
In total, 3 learning curve surgeons performed a total of 161 cases. Based on self-assessment, surgeons improved mostly in the domains “time and motion,” “respect for tissue,” and “knowledge and handling of instruments.” Learning curve surgeons were more able to detect differences in performances on the OSATS than the senior surgeon. Based on the GOALS, the biggest improvements could be seen in “depth-perception” and “autonomy.” Based on the 10-item specific checklist, all surgeons performed all 10 steps by case 10, while only 1 surgeon performed all steps adequately by case 15.
Conclusion
Based on these study results, PTED appears to be successfully adopted stepwise by 3 spine-dedicated surgeons. From 15 cases on, most steps are performed adequately. However, more cases might be necessary to achieve good clinical results. Validated tools are needed to determine the cutoff when a surgeon should be able to perform PTED independently.

Citations

Citations to this article as recorded by  Crossref logo
  • Operative time, recurrence, and complications throughout the initial learning curve in transforaminal endoscopic lumbar discectomy
    Michelle D. Poelman, Annegien Boeykens, Biswadjiet S. Harhangi, Marc L. Schröder, Victor E. Staartjes
    Acta Neurochirurgica.2026;[Epub]     CrossRef
  • Integrated Optical and Magnetic Navigation for Simplified Percutaneous Transforaminal Endoscopic Lumbar Discectomy: A Novel Approach
    Xing-Chen Yao, Jun-Peng Liu, Xin-Ru Du, Li Guan, Yong Hai, Jincai Yang, Aixing Pan
    Neurospine.2025; 22(1): 297.     CrossRef
  • Is Close Supervision by a Senior Surgeon Necessary During the Initial Days of Performing Endoscopic Lumbar Discectomy? A Retrospective Comparative Study between Two Fellowship Trained Surgeons to Assess the Learning Curve
    Syed Ifthekar, Shih-Min Lee, Sang-Ho Lee, Sang-Ha Shin, Junseok Bae
    Journal of West African College of Surgeons.2024;[Epub]     CrossRef
  • Validity Evidence for Procedure-specific Competence Assessment Tools in Orthopaedic Surgery: A Scoping Review
    Yibo Li, Robert Chan, Matthew R.G. Menon, Joanna F. Ryan, Brett Mador, Sandra M. Campbell, Simon R. Turner
    JAAOS: Global Research and Reviews.2024;[Epub]     CrossRef
  • Outcome of Percutaneous Endoscopic Lumbar Discectomy in Relation to the Surgeon’s Experience: Propensity Score Matching
    Seong Son, Michael Y. Oh, Han Byeol Park, Alexander M. Lopez
    Bioengineering.2024; 11(4): 312.     CrossRef
  • Letter to the editor regarding, “Biportal endoscopic versus microscopic discectomy for lumbar herniated disc: A randomized controlled trial” by Park et al. Concepts, analyses and interpretation of noninferiority randomized controlled trials
    Pravesh S. Gadjradj, Fabian Sommer, Rodrigo Navarro-Ramirez, Judith D. de Rooij
    The Spine Journal.2023; 23(3): 467.     CrossRef
  • Reply to letter to the editor regarding, “Biportal endoscopic versus microscopic discectomy for lumbar herniated disc: a randomized controlled trial”
    Sang-Min Park, Ho-Joong Kim
    The Spine Journal.2023; 23(3): 469.     CrossRef
  • 7,156 View
  • 195 Download
  • 7 Web of Science
  • 7 Crossref

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Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

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Cross-Cultural Adaptation and Psychometric Validation of the Dutch Version of the Core Outcome Measures Index for the Neck in Patients Undergoing Surgery for Degenerative Disease of the Cervical Spine
Neurospine. 2021;18(4):798-805.   Published online December 31, 2021
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Cross-Cultural Adaptation and Psychometric Validation of the Dutch Version of the Core Outcome Measures Index for the Neck in Patients Undergoing Surgery for Degenerative Disease of the Cervical Spine
Neurospine. 2021;18(4):798-805.   Published online December 31, 2021
Close
Objective
To perform the psychometric validation of the Dutch version of the Core Outcome Measures Index (COMI) for the neck.
Methods
A total of 178 patients, who had an indication for surgery due to degenerative cervical spinal disease, were enrolled in the study. They filled in a baseline booklet containing the Dutch version of the COMI-neck, Likert-scales for neck and arm/shoulder pain, the Neck Disability Index (NDI), the EuroQol-5 dimensions (EQ-5D) and the 12-item Short Form health survey (SF-12). Aside from analyzing construct validity using the Spearman correlation test, test-retest reliability, and responsiveness at 3 months were assessed using the intraclass correlation coefficient (ICC) and the receiver-operating characteristic (ROC) curve, respectively.
Results
The COMI-neck showed good acceptability with missing data ranging from 0% to 4.5% and some floor/ceiling effects for 3 of the domains at baseline. The COMI-summary score showed good to very good correlation with the EQ5D (ρ = -0.43), the physical component summary of the SF-12 (ρ = -0.47) and the NDI (ρ = 0.73). Individual domains showed correlations of -0.28 to 0.85 with the reference questionnaires. Test-retest reliability analysis showed an ICC of 0.91 with a minimal detectable change of 1.7. Responsiveness analysis of the COMI-neck showed an area under 0.79 under the ROC-curve. The standardized response mean for a good outcome was 1.24 and for a poor outcome 0.37.
Conclusion
The current study shows that the Dutch version of the COMI-neck is a valid, reliable and responsive Patient-Reported Outcome Measure, among patients undergoing surgery for degenerative cervical spinal disorders.

Citations

Citations to this article as recorded by  Crossref logo
  • Using the Quality Outcomes Database to Identify Minimum Clinically Important Differences for Patients With Cervical Spondylotic Myelopathy
    Anthony L. Asher, Nikita Lakomkin, Praveen V. Mummaneni, Giorgos D. Michalopoulos, Sarah E. Johnson, Paul Park, Oren N. Gottfried, Anthony M. Asher, Konstantinos Katsos, Eric A. Potts, Kevin T. Foley, Michael Y. Wang, John J. Knightly, Christopher I. Shaf
    Neurosurgery.2026; 98(6): 1347.     CrossRef
  • Cross-cultural adaptation, validation, and establishment of the minimal clinicallyimportant change score of the European Portuguese Core Outcome Measures Index in patients with cervical degenerative spine disease
    Pedro Valente Aguiar, Paulo Pereira, Anne F. Mannion, Pedro Santos Silva
    European Spine Journal.2025; 34(1): 36.     CrossRef
  • Simplified Chinese version of the core outcome measures index (COMI) for patients with neck pain: cross-cultural adaptation and validation
    Yuan Dong, Shiqi Cao, Dingfei Qian, Haichao Yu, Zelong Song, Chengqi Jia, Wenhao Hu, Xuesong Zhang
    European Spine Journal.2024; 33(2): 386.     CrossRef
  • CROSS-CULTURAL ADAPTATION AND VALIDATION OF THE TRADITIONAL CHINESE VERSION OF THE CORE OUTCOME MEASURES INDEX FOR PEOPLE WITH LOW BACK PAIN IN HONG KONG
    RUI-YAO WANG, XIAOLIN LIU, TIAN QI, WEI-XING MA, ZEXIN DING, JIAYANG LIU, YUHANG LIU, ZONG-RUN LI
    Journal of Mechanics in Medicine and Biology.2024;[Epub]     CrossRef
  • Long-Term Clinical Results of Percutaneous Cervical Nucleoplasty for Cervical Radicular Pain: A Retrospective Cohort Study
    Judith Divera de Rooij, Pravesh Shankar Gadjradj, Hans Aukes, George Groeneweg, Caroline Margina Speksnijder, Frank Johannes Huygen
    Journal of Pain Research.2022; Volume 15: 1433.     CrossRef
  • 7,283 View
  • 107 Download
  • 6 Web of Science
  • 5 Crossref