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"Byung Gwan Moon"

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"Byung Gwan Moon"

Original Article

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Difference in the Cobb Angle Between Standing and Supine Position as a Prognostic Factor After Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures
Neurospine. 2022;19(2):357-366.   Published online May 17, 2022
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Difference in the Cobb Angle Between Standing and Supine Position as a Prognostic Factor After Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures
Neurospine. 2022;19(2):357-366.   Published online May 17, 2022
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Objective
We retrospectively analyzed patients with osteoporotic vertebral compression fracture (OVCF) undergoing vertebral augmentation to compare the Cobb angle changes in the supine and standing positions and the clinical outcomes.
Methods
We retrospectively extracted the data of OVCF patients who underwent vertebral augmentation. Back pain was assessed using a visual analogue scale (VAS). Supine and standing radiographs were assessed before treatment to determine the Cobb angle and compression ratio. Receiver operating characteristic curve analysis was performed to determine the optimal cutoff to predict favorable outcomes after vertebral augmentation.
Results
A total of 249 patients were included. We observed a statistically significant increase in the VAS score change with increasing Cobb angle and compression ratio (p < 0.001), and multivariate logistic regression analysis showed that a difference in the Cobb angle (odds ratio [OR], 1.27) and compression ratio (OR, 1.12) were the independent risk factors for predicting short-term favorable outcomes after vertebral augmentation. In addition, we found that the difference in the Cobb angle (OR, 1.05) was the only factor for predicting midterm favorable outcomes after vertebral augmentation. The optimal cutoff value of the difference in the Cobb angle for predicting midterm favorable outcomes was 35.526°.
Conclusion
We found that the midterm clinical outcome after vertebral augmentation was better when there was a difference of approximately 35% or more in the Cobb angle between the standing and supine positions. Surgeons should pay attention to the difference in the Cobb angle depending on the posture when deciding to perform vertebral augmentation in patients with OVCFs.

Citations

Citations to this article as recorded by  Crossref logo
  • Construction and validation of a nomogram predictive model for safety-related influencing factors in unilateral paracentesis kyphoplasty for spinal compression fractures
    Jixiao Lang, Jingming Zhao, Rui Han, Tao Han
    European Journal of Medical Research.2026;[Epub]     CrossRef
  • The bisegmental Cobb angle in osteoporotic spine fractures: Does it influence treatment decision or functional outcome?
    Philipp Schenk, Bernhard W. Ullrich, Felix C. Kohler, Falko Schwarz, Klaus J. Schnake, Michael A. Scherer, Gregor Schmeiser, Katja Liepold, Marion Riehle, Michael Müller, Martin Bäumlein, Sebastian Katscher, Max J. Scheyerer, Georg Osterhoff, Kai Sprengel
    Brain and Spine.2026; 6: 106099.     CrossRef
  • Assessing the Diagnostic Validity of Torsobarography in Scoliosis
    Nico Stecher, Lea Richter, Arkadiusz Łukasz Żurawski, Andreas Heinke, Maximilian Robert Harder, Thurid Jochim, Paula Schumann, Wojciech Piotr Kiebzak, Hagen Malberg
    Sensors.2025; 25(8): 2485.     CrossRef
  • Short-Segment Fixation for Thoracolumbar Kyphosis Caused by Osteoporotic Vertebral Compression Fractures: A Case Series
    Qiu-Qi Zhang, Jia Song, Hai-Tao Liu, Zhi-Hui Liang, Fu-Chao Zhou, Jiang Shao, Yue-Hui Zhang
    World Neurosurgery.2025; 197: 123912.     CrossRef
  • Conservative Treatment with Teriparatide Versus Vertebroplasty for Acute Osteoporotic Vertebral Compression Fractures: A Meta-Analysis
    Subum Lee, Junseok W. Hur, Younggyu Oh, Sungjae An, Yeongu Chung, Danbi Park, Jin Hoon Park
    Journal of Clinical Medicine.2025; 14(11): 3967.     CrossRef
  • A comparative analysis of three distinct approaches for the management of type A1 traumatic thoracolumbar fractures: a retrospective cohort study with a minimum 6-year follow-up
    Jiangtao Wang, Huiming Yang, Mario Ganau, Yuhang Wang, Junxian Miao, Liang Yan, Biao Wang
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Stem Cell and Regenerative Therapies for the Treatment of Osteoporotic Vertebral Compression Fractures
    Songzi Zhang, Yunhwan Lee, Yanting Liu, Yerin Yu, Inbo Han
    International Journal of Molecular Sciences.2024; 25(9): 4979.     CrossRef
  • Comparison of the Clinical Efficacy of Anabolic Agents and Bisphosphonates in the Patients With Osteoporotic Vertebral Fracture: Systematic Review and Meta-analysis of Randomized Controlled Trials
    Ikchan Jeon, Sung Bae Park, Bong Ju Moon, Miyoung Choi, Sung Uk Kuh, Jongtae Kim
    Neurospine.2024; 21(2): 416.     CrossRef
  • A novel radiological assessment to identify acute vertebral compression fractures: A pilot observational study
    Keisuke Tsuruta, Toru Ueyama, Tomoo Watanabe, Yasunori Kobata, Kenichi Nakano, Hidetada Fukushima
    Acute Medicine & Surgery.2023;[Epub]     CrossRef
  • Quantitative Comparison of Vertebral Structural Changes After Percutaneous Vertebroplasty Between Unilateral Extrapedicular Approach and Bilateral Transpedicular Approach Using Voxel-Based Morphometry
    Tae Kim, Jinah Park, Jihoon Cho, Jin Seok Yi, Hong-Jae Lee
    Neurospine.2023; 20(4): 1287.     CrossRef
  • Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty
    Masahiro Kawanishi, Hidekazu Tanaka, Yutaka Ito, Makoto Yamada, Kunio Yokoyama, Akira Sugie, Naokado Ikeda
    Neurospine.2023; 20(4): 1124.     CrossRef
  • The Effectiveness of Vertebral Height Restoration Based on the Vertebroplasty Procedure Used to Treat Osteoporotic Vertebral Fractures
    Kunio Yokoyama, Naokado Ikeda, Hidekazu Tanaka, Yutaka Ito, Akira Sugie, Makoto Yamada, Masahiko Wanibuchi, Masahiro Kawanishi
    Neurospine.2023; 20(4): 1159.     CrossRef
  • Optimal Strategies for the Treatment of Osteoporotic Spinal Diseases
    Dae-Chul Cho
    Neurospine.2023; 20(4): 1095.     CrossRef
  • 9,075 View
  • 261 Download
  • 14 Web of Science
  • 13 Crossref

Clinical Article

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Efficacy and Safety of Sodium Hyaluronate with 1,4-Butanediol Diglycidyl Ether Compared to Sodium Carboxymethylcellulose in Preventing Adhesion Formation after Lumbar Discectomy
Korean J Spine. 2015;12(2):41-47.   Published online June 30, 2015
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Efficacy and Safety of Sodium Hyaluronate with 1,4-Butanediol Diglycidyl Ether Compared to Sodium Carboxymethylcellulose in Preventing Adhesion Formation after Lumbar Discectomy
Korean J Spine. 2015;12(2):41-47.   Published online June 30, 2015
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Objective

Epidural injection of hyaluronic acid may prevent adhesion formation after spine surgery, but the compounds used to stabilize hyaluronidase could interfere with its anti-adhesion effects. The present study was conducted as a clinical trial to evaluate the efficacy and safety of an experimental medical gel in preventing adhesion formation.

Methods

This study was designed as a multicenter, randomized, double-blind, and comparative controlled clinical trial with an observation period of 6 weeks. Subjects were randomly assigned into two groups: group A with sodium hyaluronate + 1,4-butanediol diglycidyl ether (BDDE) and group B with sodium hyaluronate + sodium carboxymethylcellulose (CMC). Visual analogue scale (VAS) of back and leg pain and the Oswestry disability index (ODI) and scar score ratings were assessed after surgery.

Results

Mean scar grade was 2.37±1.13 in group A and 2.75±0.97 in group B, a statistically significant difference (p=0.012). VAS of back and leg pain and ODI scores decreased significantly from baseline to 3 and 6 weeks postoperatively in both groups (p<0.001). However, VAS and ODI scores were not statistically different between groups A and B at baseline or at 3 and 6 weeks after operation (p>0.3). The number of adverse reactions related to the anti-adhesion gels was not statistically different (p=0.569), but subsequent analysis of nervous adverse reactions showed group B was superior with a statistically difference (p=0.027).

Conclusion

Sodium hyaluronate with BDDE demonstrated similar anti-adhesion properties to sodium hyaluronate with CMC. But, care should be used to nervous adverse reactions by using sodium hyaluronate with BDDE.

Citations

Citations to this article as recorded by  Crossref logo
  • Are We Overlooking Harms of BDDE-Cross-Linked Dermal Fillers? A Scoping Review
    Marta Wojtkiewicz, Albert Stachura, Bartłomiej Roszkowski, Natalia Winiarska, Karolina Kazimierska, Kamilla Stachura
    Aesthetic Plastic Surgery.2024; 48(23): 5147.     CrossRef
  • Evaluation of the optimal dose for maximizing the anti-adhesion performance of a self-degradable dextran-based material
    Woogi Hyon, Suong-Hyu Hyon, Kazuaki Matsumura
    Carbohydrate Polymer Technologies and Applications.2022; 4: 100255.     CrossRef
  • MORPHOLOGICAL PATTERNS OF DEVELOPMENT AND PREVENTION OF EXPERIMENTAL EPIDURAL FIBROSIS
    I.A. SHURYGINA, A.P. ZHIVOTENKO, O.A. GOLDBERG, V.A. SOROKOVIKOV
    AVICENNA BULLETIN.2022; 24(2): 176.     CrossRef
  • Therapeutic niche of hyaluronic acid derivatives in osteoarthritis
    I. G. Krasivina, L. N. Dolgova, N. V. Dolgov
    Meditsinskiy sovet = Medical Council.2021; (10): 123.     CrossRef
  • Using cross-linked hyaluronic acid gel to prevent postoperative lumbar epidural space adhesion: in vitro and in vivo studies
    Kun Wang, Xiao long Li, Jinbo Liu, Xiaoliang Sun, Huilin Yang, Xin Gao
    European Spine Journal.2020; 29(1): 129.     CrossRef
  • Antiadhesion effect of the C17 glycerin ester of isoprenoid-type lipid forming a nonlamellar liquid crystal
    Takahide Murakami, Ichiro Hijikuro, Kota Yamashita, Shigeru Tsunoda, Kenjiro Hirai, Takahisa Suzuki, Yoshiharu Sakai, Yasuhiko Tabata
    Acta Biomaterialia.2019; 84: 257.     CrossRef
  • Advances in biomaterials for preventing tissue adhesion
    Wei Wu, Ruoyu Cheng, José das Neves, Jincheng Tang, Junyuan Xiao, Qing Ni, Xinnong Liu, Guoqing Pan, Dechun Li, Wenguo Cui, Bruno Sarmento
    Journal of Controlled Release.2017; 261: 318.     CrossRef
  • Efficacy of hyaluronic acid and hydroxyethyl starch in preventing adhesion following endoscopic sinus surgery
    Su-Jong Kim, Jae-Min Shin, Eun Jung Lee, Il-Ho Park, Heung-Man Lee, Kyung-Su Kim
    European Archives of Oto-Rhino-Laryngology.2017; 274(10): 3643.     CrossRef
  • A glance at … dietary emulsifiers, the human intestinal mucus and microbiome, and dietary fiber
    Michael J. Glade, Michael M. Meguid
    Nutrition.2016; 32(5): 609.     CrossRef
  • Dual crosslinked hyaluronic acid nanofibrous membranes for prolonged prevention of post-surgical peritoneal adhesion
    Chialin Sheu, K. T. Shalumon, Chih-Hao Chen, Chang-Yi Kuo, Yi Teng Fong, Jyh-Ping Chen
    Journal of Materials Chemistry B.2016; 4(41): 6680.     CrossRef
  • 12,325 View
  • 157 Download
  • 10 Crossref

Original Article

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The Comparative Study for Clinical and Radiologic Results of Unilateral Kyphoplasty and Bilateral Vertebroplasty.
Korean J Spine. 2010;7(4):242-248.
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The Comparative Study for Clinical and Radiologic Results of Unilateral Kyphoplasty and Bilateral Vertebroplasty.
Korean J Spine. 2010;7(4):242-248.
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OBJECTIVE
To elucidate postoperative clinical and radiologic efficacy of unilateral kyphoplasty compared for percutaneous bilateral vertebroplasty.
METHODS
One hundred patients with osteoporotic compression fracture at thoracolumbar junction were enrolled in this study. The kyphotic angle and reduction rate were measured to evaluate the vertebral restoration. Visual analog scale (VAS) for pain and short form-36 (SF-36) and Oswestry Disability Index (ODI) for functional outcome were recorded by 1 year postoperatively. Cement extravasation and adjacent vertebral fractures were monitored.
RESULTS
Visual analog scale for pain was not statistically different through the follow up in both groups (p=0.38). The preoperative SF-36 and ODI scores were similar (p>0.05) but the difference in ODI score and standardized physical component scale reached statistical significance (p=0.04, p=0.03) and unilateral kyphoplasty group was getting better functional status. Reduction rate of vertebral body was 42.5+/-7.8% for the vertebroplasty group and 66.3+/-8.1% for the unilateral kyphoplasty group (p<0.001) and loss of reduction was 4.5+/-3.5% and 1.7+/-2.5% (p<0.0001) respectively. There were six complications of cement extraosseous leakage into the spinal canal in vertebroplasty only.
CONCLUSION
Unilateral kyphoplasty in compare with vertebroplasty is safer for cement leakage and immediately reduces back pain and restore kyphotic deformities in addition to the prevention of subsequent compression fracture.
  • 3,154 View
  • 22 Download

Case Report

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Myelography Induced Fatal Complications; Seizure and Rhabdomyolysis.
Korean J Spine. 2010;7(3):192-194.
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Myelography Induced Fatal Complications; Seizure and Rhabdomyolysis.
Korean J Spine. 2010;7(3):192-194.
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Myelography has been generally regarded as a safe procedure. However, epidural hematoma and some allergic reactions have been reported, although rarely, as complications of myelography. Herein, we report a patient who experienced seizure and rhabdomyolysis after iopamidol injection with a review of the pertinent literature. A 75-year-old man with no medical history of seizure underwent lumbar spine myelography for the evaluation of the lumbar spine stenosis. After several hours following injection with water-soluble nonionic contrast medium(Iopamidol), he had a generalized tonic-clonic seizure, which progressed into a complex partial. In spite of the efforts of injecting anti-seizure medications, intermittent short-lasting seizure activity continued for hours and brain computed tomographic scan showed a large amount of hyperdense iopamidol in the subarachnoid space. As a consequence, he suffered from rhabdomyolysis-induced acute renal failure. The patient recovered from the contrast-induced acute renal failure after several days of treatment in the intensive care unit and hemodialysis. Fatal complications, such as seizure and rhabdomyolysis, can occur after myelography. Prompt diagnosis and treatment are needed.
  • 3,478 View
  • 26 Download