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"Do Heum Yoon"

Review Article

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Surgical Strategies for Cervical Deformities Associated With Neuromuscular Disorders
Neurospine. 2020;17(3):513-524.   Published online September 30, 2020
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Surgical Strategies for Cervical Deformities Associated With Neuromuscular Disorders
Neurospine. 2020;17(3):513-524.   Published online September 30, 2020
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Neuromuscular disorders (NMDs) are diseases involving the upper and lower motor neurons and muscles. In patients with NMDs, cervical spinal deformities are a very common issue; however, unlike thoracolumbar spinal deformities, few studies have investigated these disorders. The patients with NMDs have irregular spinal curvature caused by poor balance and poor coordination of their head, neck, and trunk. Particularly, cervical deformity occurs at younger age, and is known to show more rigid and severe curvature at high cervical levels. Muscular physiologic dynamic characteristics such as spasticity or dystonia combined with static structural factors such as curvature flexibility can result in deformity and often lead to traumatic spinal cord injury. In addition, postoperative complication rate is higher due to abnormal involuntary movement and muscle tone. Therefore, it is important to control abnormal involuntary movement perioperatively along with strong instrumentation for correction of deformity. Various methods such as botulinum toxin injection, physical therapy, muscle division technique, or intrathecal baclofen pump implant may help control abnormal involuntary movements and improve spinal stability. Surgical management for cervical deformities associated with NMDs requires a multidisciplinary effort and a customized strategy.

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  • Predictive Factors for Postoperative Outcomes of Cervical Spondylotic Myelopathy in Individuals With Cerebral Palsy
    Su Ji Lee, Jihye Hwang, Min Gyu Kang, Minjae Cho, Yoon Ha, Sung-Rae Cho
    Global Spine Journal.2026; 16(1): 75.     CrossRef
  • A review of treatment methods for movement disorders
    Mahdi Khezri, Shakiba Afsar
    Behavioural Brain Research.2026; 500: 115979.     CrossRef
  • Morphogenetic Designs, and Disease Models in Central Nervous System Organoids
    Minsung Bock, Sung Jun Hong, Songzi Zhang, Yerin Yu, Somin Lee, Haeeun Shin, Byung Hyune Choi, Inbo Han
    International Journal of Molecular Sciences.2024; 25(14): 7750.     CrossRef
  • Suporte ativo controlado por joystick para hipotonia cervical infantil
    Caroline Dantas Brasil Sfair, Maria Clara Rocha de Jesus, Manoel da Silva Filho, Carla Viana Dendasck
    Revista Científica Multidisciplinar Núcleo do Conhecimento.2024; : 92.     CrossRef
  • Perioperative opioid-minimization approach as a useful protocol in the management of patients with Ehlers–Danlos syndrome-hypermobility type, craniocervical instability and severe chronic pain who are to undergo occipito-cervical fixation
    Carlos Ramírez-Paesano, Claudia Rodiera Clarens, Allan Sharp Segovia, Alan Coila Bustinza, Josep Rodiera Olive, Albert Juanola Galceran
    Orphanet Journal of Rare Diseases.2023;[Epub]     CrossRef
  • Deep Brain Stimulation Before Anterior Cervical Discectomy and Fusion for a Patient With Cervical Dystonia and Cervical Myelopathy: A Case Report
    Michael Folse, Ryan Diaz, Racheal Peterson, Jamie Toms
    Cureus.2023;[Epub]     CrossRef
  • Clinical Issues in Indication, Correction, and Outcomes of the Surgery for Neuromuscular Scoliosis: Narrative Review in Pedicle Screw Era
    Hak Sun Kim, Ji Won Kwon, Kun-Bo Park
    Neurospine.2022; 19(1): 177.     CrossRef
  • Surgical Strategies and Perioperative Considerations for Cervical Deformity With Cerebral Palsy: A Comprehensive Review of the Literature
    Hyung Cheol Kim, Sung Han Oh, Jae Keun Oh, Yoon Ha
    Neurospine.2022; 19(4): 868.     CrossRef
  • Two Cases of Spinal Surgery in Adult Patients with Wilson’s Disease
    Akinori Tani, Sumito Kinjo, Keisuke Ito, Yohei Ishimine, Yoshiro Musha
    Spinal Surgery.2022; 36(2): 182.     CrossRef
  • Best Practices for the Orthopaedic Care of Children with Spinal Muscular Atrophy: A Consensus Statement from the European Neuromuscular Centre Standard of Care Orthopaedic Working Group
    Michael Vitale, Benjamin Roye, Zachary Bloom, Jennifer A. Kunes, Hiroko Matsumoto, David Roye, David Farrington, Jack Flynn, Matthew Halanski, Carol Hasler, Lotfi Miladi, Susana Quijano-Roy, Christopher Reilly, Paul Sponseller, Muharrem Yazici, Brian Snyd
    Journal of the Pediatric Orthopaedic Society of North America.2022; 4(1): 296.     CrossRef
  • Scoliosis and Gastroesophageal Reflux Disease in Adults
    Fahri Eryilmaz , Faheem Ahmed, Asim K Rehmani, Sundas Karimi, Aamna Qazi, Sufyan Mustafa, Arif Zulfiqar, Zubia Nadeem, Ayyaz A Sultan, Umar Farooque
    Cureus.2021;[Epub]     CrossRef
  • Factors Affecting Postoperative Complications and Outcomes of Cervical Spondylotic Myelopathy with Cerebral Palsy : A Retrospective Analysis
    Hyung Cheol Kim, Hyeongseok Jeon, Yeong Ha Jeong, Sangman Park, Seong Bae An, Jeong Hyun Heo, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Yoon Ha, Sung-Rae Cho
    Journal of Korean Neurosurgical Society.2021; 64(5): 808.     CrossRef
  • 12,155 View
  • 216 Download
  • 9 Web of Science
  • 12 Crossref

Case Report

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Rosai-Dorfman Disease in Thoracic Spine: A Rare Case of Compression Fracture
Korean J Spine. 2014;11(3):198-201.   Published online September 30, 2014
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Rosai-Dorfman Disease in Thoracic Spine: A Rare Case of Compression Fracture
Korean J Spine. 2014;11(3):198-201.   Published online September 30, 2014
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Sinus histiocytosis with massive lymphadenopathy known as Rosai-Dorfman disease is characterized by painless bilateral cervical lymphadenopathy. Extranodal manifestations are uncommon and spinal involvement is rare. A 15-year-old man presented with intermittent midthoracic back pain only. He had no specific findings on neurologic examinations, hematologic and biochemical laboratory tests. Radiological examination of thoracic spine revealed collapse of T6 vertebrae with thoracic kyphosis and osteolytic lesion of T12 vertebra body. He underwent a removal of bone tumor, anterior reconstruction with mesh and pedicle screw fixation via posterior approach for pathologic confirmation and stabilization. Histopathologic study of the lesion revealed focal infiltration of large histiocytes showing emperipolesis. Immunochemistry stain of histiocytes was positive for CD68 and S-100 but negative for CD1a. This report presents a rare case and literature review of extranodal Rosai-dorfman disease in thoracic spine.

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  • Diagnosis and Management of Extranodal Rosai-Dorfman Disease Isolated to the Thoracic Spine: Systematic Review and Illustrative Case
    Rithvik Ramesh, Robert C. Osorio, Melike Pekmezci, Lauren Boreta, Debajyoti Datta, Nima Alan
    World Neurosurgery.2026; 212: 125082.     CrossRef
  • Isolated Rosai-Dorfman disease of the spine: A systematic literature review
    Maroua Slouma, Sirine Bouzid, Karima Tlili, Dahmani Yedaes, Khaled Radhwen, Imen Gharsallah
    Clinical Neurology and Neurosurgery.2024; 239: 108206.     CrossRef
  • Diagnosis and treatment of Rosai-Dorfman disease of the spine: a systematic literature review
    Pan-pan Hu, Feng Wei, Xiao-guang Liu, Zhong-jun Liu
    Systematic Reviews.2021;[Epub]     CrossRef
  • Primary Rosai‑Dorfman disease of bone arising in the infantile ilium: A case report
    Yuya Izubuchi, Koji Suzuki, Yoshiaki Imamura, Hajime Katayama, Yusei Ohshima, Akihiko Matsumine
    Experimental and Therapeutic Medicine.2020;[Epub]     CrossRef
  • Long-Term Outcome of Spinal Extranodal Rosai-Dorfman Disease: A Report of Two Cases and Systematic Review
    Saleh S. Baeesa, Hani Mahboob, Yazid Maghrabi, Mohammad Binmahfoodh, Jaudah Almaghrabi
    World Neurosurgery.2020; 144: 1.     CrossRef
  • Nonresectable Thoracic Rosai-Dorfman Disease: A Case Report and Review of the Literature
    Cheng-Kai Lin, Yu-Duan Tsai
    World Neurosurgery.2019; 132: 309.     CrossRef
  • An Institutional Review of Tuberculosis Spine Mimics on MR Imaging: Cases of Mistaken Identity
    SunithaPalasamudram Kumaran, PushpaBhari Thippeswamy, BhavanaNagabhushan Reddy, Sankar Neelakantan, Sanjaya Viswamitra
    Neurology India.2019; 67(6): 1408.     CrossRef
  • 9,185 View
  • 79 Download
  • 7 Crossref

Clinical Articles

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Initial Clinical Outcomes of Minimally Invasive Lateral Lumbar Interbody Fusion in Degenerative Lumbar Disease: A Preliminary Report on the Experience of a Single Institution with 30 Cases
Korean J Spine. 2012;9(3):187-192.   Published online September 30, 2012
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Initial Clinical Outcomes of Minimally Invasive Lateral Lumbar Interbody Fusion in Degenerative Lumbar Disease: A Preliminary Report on the Experience of a Single Institution with 30 Cases
Korean J Spine. 2012;9(3):187-192.   Published online September 30, 2012
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Objective

The object of this study was to evaluate the clinical and radiological outcomes of minimally invasive lateral lumbar interbody fusion.

Methods

This study included 30 patients who underwent minimally invasive lateral lumbar interbody fusion at our hospital between May 2011 and February 2012 for the following diagnoses: degenerative disc disease, adjacent-segment degeneration, degenerative spondylolisthesis and lumbar degenerative scoliosis. Pain assessment was reported from 0 to 10 using a subjective visual analog scale (VAS) upon admission and at every follow-up day. Lumbar X-rays were obtained in the standing position upon admission and the 1st and 5th postoperative day, and at every follow-up day after the operation. The heights of the intervertebral disc space and neural foramen were measured using an electronic caliper with the PACS software. The surgical outcome was assessed as excellent, good, fair or poor using the Odom scale at the last follow-up.

Results

The mean VAS for low back pain were 4.93±1.47 on admission and 2.01±1.35 at last follow-up, respectively, and for leg pain, the scores were 4.87±2.16 on admission and 1.58±1.52 at last follow-up. The mean height of intervertebral disc space increased by 34% (7.93±2.33 preoperatively, and 11.09±4.33 immediately after surgery, p<0.01). The mean height of neural foramen also increased by 6.4% without any statistical significance (19.17±2.84 preoperatively, and 20.49±4.50 immediately after the surgery). Minimally invasive lateral lumbar interbody fusion was successful in 27 patients (90%) at last follow-up. Surgical complications were reported as transient postoperative thigh sensory changes (5 patients, 16.7%), transient psoas muscle weakness (3 patients, 10%), cage migration (2 patients, 6.7%), lumbar plexus injury (1 patient, 3.3%), and pain aggravation (1 patient, 3.3%).

Conclusion

The minimally invasive lateral lumbar interbody fusion is a safe and effective procedure for treating degenerative lumbar disease with good outcomes and moderate complications. Further follow-up is necessary to establish its safety and efficacy.

Citations

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  • Lumbar disc space height in relation to neural foraminal dimensions and patient characteristics: A morphometric analysis from L1-S1 using computed tomography
    David Shin, Ethan Vyhmeister, Daniel Im, Andrew Fay, Owen Faehner, Andrew Cabrera, Alexander Bouterse, Lauren Seo, Derran Bedward, Mei Carter, Davis Carter, Jacob Razzouk, Omar Ramos, Nathaniel Wycliffe, Wayne Cheng, Olumide Danisa
    Brain and Spine.2025; 5: 104162.     CrossRef
  • Comparative Analysis of ABM/P-15, Bone Morphogenic Protein and Demineralized Bone Matrix after Instrumented Lumbar Interbody Fusion
    Ashwin Sathe, Sang-Ho Lee, Shin-Jae Kim, Sang Soo Eun, Yong Soo Choi, Shih-min Lee, Ju-Wan Seuk, Yoon Sun Lee, Sang-Ha Shin, Junseok Bae
    Journal of Korean Neurosurgical Society.2022; 65(6): 825.     CrossRef
  • Lateral Lumbar Interbody Fusion: Review of Surgical Technique and Postoperative Multimodality Imaging Findings
    Pattana Wangaryattawanich, Hrishikesh A. Kale, Adam S. Kanter, Vikas Agarwal
    American Journal of Roentgenology.2021; 217(2): 480.     CrossRef
  • Lateral Lumbar Interbody Fusion: What is the Evidence of Indirect Neural Decompression? A Systematic Review of the Literature
    Matteo Formica, Emanuele Quarto, Andrea Zanirato, Lorenzo Mosconi, Davide Vallerga, Irene Zotta, Maddalena Lontaro Baracchini, Carlo Formica, Lamberto Felli
    HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery.2020; 16(2): 143.     CrossRef
  • Complications for minimally invasive lateral interbody arthrodesis: a systematic review and meta-analysis comparing prepsoas and transpsoas approaches
    Corey T. Walker, S. Harrison Farber, Tyler S. Cole, David S. Xu, Jakub Godzik, Alexander C. Whiting, Cory Hartman, Randall W. Porter, Jay D. Turner, Juan Uribe
    Journal of Neurosurgery: Spine.2019; 30(4): 446.     CrossRef
  • Potential and Limitations of Neural Decompression in Extreme Lateral Interbody Fusion—A Systematic Review
    Gernot Lang, Moritz Perrech, Rodrigo Navarro-Ramirez, Ibrahim Hussain, Brenton Pennicooke, Farah Maryam, Mauricio J. Avila, Roger Härtl
    World Neurosurgery.2017; 101: 99.     CrossRef
  • 8,949 View
  • 89 Download
  • 6 Crossref

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Correction of Coronal Imbalance in Degenerative Lumbar Spine Disease Following Direct Lateral Interbody Fusion (DLIF)
Korean J Spine. 2012;9(3):176-180.   Published online September 30, 2012
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Correction of Coronal Imbalance in Degenerative Lumbar Spine Disease Following Direct Lateral Interbody Fusion (DLIF)
Korean J Spine. 2012;9(3):176-180.   Published online September 30, 2012
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Objective

The authors have recently been using a surgical technique of minimally invasive direct lateral interbody fusion (DLIF) for correcting of coronal imbalance. The purpose of this study was to evaluate the surgical outcome and complication of DLIF.

Methods

We undertook retrospective analysis of a consecutive series of 8 DLIF procedures in Degenerative lumbar spine disease since May 2011. Four patients underwent DLIF only, and the others underwent combined DLIF and posterior fixation. Data on intra- and postoperative complications were collected. The pre- and postoperative X-rays were reviewed. We investigated coronal deformity, Cobb's angle, and apical vertebral translation (AVT). The mean follow-up period was months with a range of 2 to 8 months.

Results

A mean preoperative coronal Cobb's angle was 21.8° (range 11.5-32.4°). Following after DLIF, the mean Cobb's angle was decreased to 13.0° (range 2.9-21.5°). Following additional posterior screw fixation, mean Cobb's angle was further decreased to 7.4° (range 2.9-13.2°). A mean preoperative AVT was 2.0 cm(range 0.6-3.5 cm), and improved to 1.4 cm(range 0.3-2.4 cm) and 0.8 cm(range 0.2-1.8 cm) postoperatively (DLIF and, posterior fixation respectively). One patient (12.5%) showed cage migration during follow-up period. Two patients (25%) developed motor weakness, and 4 patients (50%) experienced postoperative thigh paresthesias or dysesthesias. During follow up period, motor weakness had resolved in 1 patient. Sensory symptoms were improved in all patients at the last follow-up.

Conclusion

Degenerative lumbar disease can be effectively corrected by DLIF with acceptable complications.

Citations

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  • Stand-Alone Lateral Lumbar Interbody Fusion and Lateral Lumbar Interbody Fusion With Supplemental Posterior Instrumentation in the Treatment of Lumbar Degenerative Disease: A Meta-Analysis and Systematic Review
    XiaoCheng Zhou, Qiujun Zhou, Xiaoliang Jin, Jinjie Zhang, Zhoufeng Song
    Global Spine Journal.2025; 15(2): 1375.     CrossRef
  • Comparison of instrumented and stand-alone lateral lumbar interbody fusion for lumbar degenerative disease: a systematic review and meta-analysis
    Lianghai Jiang, Lantao Liu, Liang Dong, Zhengwei Xu, Xiaobo Zhang, Lixiong Qian
    BMC Musculoskeletal Disorders.2024;[Epub]     CrossRef
  • Kickstand Rod With Asymmetric Pedicle Subtraction Osteotomy for Treatment of Adult Kyphoscoliosis With Severe Coronal Imbalance
    Michael M. Safaee, Patrick R. Maloney, Vedat Deviren, Christopher P. Ames
    Operative Neurosurgery.2022; 22(6): e245.     CrossRef
  • Assessing the differences in operative and patient-reported outcomes between lateral approaches for lumbar fusion: a systematic review and indirect meta-analysis
    Atiq ur Rehman Bhatti, Joseph Cesare, Waseem Wahood, Mohammed Ali Alvi, Chiduziem E. Onyedimma, Abdul Karim Ghaith, Oluwatoyin Akinnusotu, Sally El Sammak, Brett A. Freedman, Arjun S. Sebastian, Mohamad Bydon
    Journal of Neurosurgery: Spine.2022; 37(4): 498.     CrossRef
  • Is instrumented lateral lumbar interbody fusion superior to stand-alone lateral lumbar interbody fusion for the treatment of lumbar degenerative disease? A meta-analysis
    Honghao Yang, Jingwei Liu, Yong Hai
    Journal of Clinical Neuroscience.2021; 92: 136.     CrossRef
  • Coronal balance with circumferential minimally invasive spinal deformity surgery for the treatment of degenerative scoliosis: are we leaning in the right direction?
    Corey T. Walker, Jakub Godzik, Santiago Angel, Juan Pedro Giraldo, Jay D. Turner, Juan S. Uribe
    Journal of Neurosurgery: Spine.2021; 34(6): 879.     CrossRef
  • Factors Influencing Early Disc Height Loss Following Lateral Lumbar Interbody Fusion
    Arun-Kumar Kaliya-Perumal, Tamara Lee Ting Soh, Mark Tan, Jacob Yoong-Leong Oh
    Asian Spine Journal.2020; 14(5): 601.     CrossRef
  • The impact of adding posterior instrumentation to transpsoas lateral fusion: a systematic review and meta-analysis
    Mohammed Ali Alvi, Redab Alkhataybeh, Waseem Wahood, Panagiotis Kerezoudis, Sandy Goncalves, M. Hassan Murad, Mohamad Bydon
    Journal of Neurosurgery: Spine.2019; 30(2): 211.     CrossRef
  • Complications for minimally invasive lateral interbody arthrodesis: a systematic review and meta-analysis comparing prepsoas and transpsoas approaches
    Corey T. Walker, S. Harrison Farber, Tyler S. Cole, David S. Xu, Jakub Godzik, Alexander C. Whiting, Cory Hartman, Randall W. Porter, Jay D. Turner, Juan Uribe
    Journal of Neurosurgery: Spine.2019; 30(4): 446.     CrossRef
  • Effect of Cage in Radiological Differences between Direct and Oblique Lateral Interbody Fusion Techniques
    Myeong Jin Ko, Seung Won Park, Young Baeg Kim
    Journal of Korean Neurosurgical Society.2019; 62(4): 432.     CrossRef
  • Clinical and Radiological Outcomes of a New Cage for Direct Lateral Lumbar Interbody Fusion
    Shin Jae Kim, Young Seok Lee, Young Baeg Kim, Seung Won Park, Vo Tan Hung
    Korean Journal of Spine.2014; 11(3): 145.     CrossRef
  • 10,479 View
  • 90 Download
  • 11 Crossref

Original Articles

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Surgical Outcomes of Spine Disorders in Patients with Parkinson's Disease.
Korean J Spine. 2011;8(3):208-214.
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Surgical Outcomes of Spine Disorders in Patients with Parkinson's Disease.
Korean J Spine. 2011;8(3):208-214.
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PURPOSE
Patients with Parkinson's disease also commonly have movement disorders, osteoporosis, and other comorbidities. These patients are more likely to have complications after spinal surgery. The aim of the present study is to show the relation ship between complications of spinal surgery and Parkinson's disease.
METHODS
A computerized search using diagnostic and procedural codes identified 13 patients with Parkinson's disease who underwent spinal surgery between January 1998 and December 2010. Their medical records and imaging studies were reviewed and recent updatesfor all patients were done by telephone interview.
RESULTS
Retrospectively, 13 consecutive patients were reviewed. The mean age was 63.8 (range 44~87) years old and the mean durationof Parkinson's disease was 7.6 (range 1~22) years at the time of the index procedure. The mean T score of the lumbar spine on Dual-energy X-ray absorptiometry (DEXA) scan bone mineral density (BMD) was -2.5 (range -1.0~-5.1). These patients had nine lumbar lesions, two thoracic lesions, one cervical lesion, and one thoracolumbar lesion. Nine patients required no more surgical treatment for lesions which had been previously operated on (index level). However, four patients (30.8%) needed at least one more operation related to their index procedure; segmental degeneration on the adjacent levels in two, retropulsion of an intervertebral cage with screw loosening in one, and pedicle fracture in one.
CONCLUSION
It has been reported that patients with Parkinson's disease have high complication rates in spinal surgery. Spine surgeons should be aware of the risk of complications and need to conduct careful follow-up after the surgery.

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  • Morphogenetic Designs, and Disease Models in Central Nervous System Organoids
    Minsung Bock, Sung Jun Hong, Songzi Zhang, Yerin Yu, Somin Lee, Haeeun Shin, Byung Hyune Choi, Inbo Han
    International Journal of Molecular Sciences.2024; 25(14): 7750.     CrossRef
  • 6,917 View
  • 41 Download
  • 1 Crossref

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Comparison of the Outcomes after Intralesional, Intracisternal, and Intravenous Transplantation of Human Bone Marrow Derived Mesenchymal Stem Cells for Spinal Cord Injured Rat.
Korean J Spine. 2011;8(2):88-96.
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Comparison of the Outcomes after Intralesional, Intracisternal, and Intravenous Transplantation of Human Bone Marrow Derived Mesenchymal Stem Cells for Spinal Cord Injured Rat.
Korean J Spine. 2011;8(2):88-96.
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OBJECTIVE
Mesenchymal stem cells (MSCs) have shown promise in potentially repairing injured spinal cord. These and similar cell types are being tested clinically, but the understanding about delivering method and subsequent results is lacking. This study was designed to compare the MSCs engraftment results after intralesional, intracisternal, or intravenous injection in a rat with spinal cord injury (SCI).
METHODS
A total of 48 male Sprague-Dawley rats (300-350 g in size) were used with 12 in each group. Allogenic MSCs were cultured from human bone marrow aspirates. The SCI was induced using an NYU (New York University) impactor and MSCs were transplanted 1 week after the SCI. Behavioral testing was performed weekly for 6 weeks. The recipients were analyzed histologically to evaluate the extent of cell delivery and survival at the injury site.
RESULTS
All three experimental groups showed better behavioral recovery compared with the control group since 6 weeks after stem cell injection (p<0.05). The intracisternal injection group showed the best functional improvement (p<0.05). The intralesional injection group showed the best engraftment until 4 weeks after stem cell injection (p<0.05). A number of the injected MSCs were trapped in the spleen in the intravenous injection group.
CONCLUSION
Transplantation of stem cells by a variety of routes can deliver cells with the potential to repair injured spinal cord. Intracisternal injection can easily be translated to patients after some modifications, thus accelerating clinical application of cell therapies.
  • 5,542 View
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Case Reports

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Rapid Recurrence of Spinal Idiopathic Hypertrophic Pachymeningitis: A Case Report.
Korean J Spine. 2008;5(3):211-214.
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Rapid Recurrence of Spinal Idiopathic Hypertrophic Pachymeningitis: A Case Report.
Korean J Spine. 2008;5(3):211-214.
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Idiopathic hypertrophic pachymeningitis is a rare inflammatory disorder of the dura mater. Spinal involvement is extremely rare and there are few case reports. We present a 36 year-old female of idiopathic hypertrophic spinal pachymeningitis compressing thoracic spinal cord which showed rapid recurrence.
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Combined en Bloc Spondylectomy and Chest Wall Resection for Malignant Tumors Invading Spinal Column and Chest Wall.
Korean J Spine. 2009;6(3):221-224.
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Combined en Bloc Spondylectomy and Chest Wall Resection for Malignant Tumors Invading Spinal Column and Chest Wall.
Korean J Spine. 2009;6(3):221-224.
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We performed combined spondylectomy for 2 patients of malignant tumors invading spinal column and chest wall. For one patient with Pancoast tumor, anterolateral thoracotomy, apical lobectomy, chest wall resection, and hemispondylectomy were performed. For another patient with solitary metastatic tumor from nasopharyngeal cancer, posterolateral thoracotomy, chest wall resection, and total en bloc spondylectomy were performed with anterior and posterior instrumentation. The tumor including invaded chest wall and spinal column werewas removed completely in both patients. No local recurrence was found at 18 months follow-up evaluation in both patients.
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Original Articles

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Clinical and Radiological Outcome of an Interspinous Dynamic Stabilization System in Degenerative Lumbar Disease:24 Cases with Over 24 Months of Follow-up.
Korean J Spine. 2009;6(3):175-180.
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Clinical and Radiological Outcome of an Interspinous Dynamic Stabilization System in Degenerative Lumbar Disease:24 Cases with Over 24 Months of Follow-up.
Korean J Spine. 2009;6(3):175-180.
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OBJECTIVE
The purpose of this study was to analyze the clinical and radiological outcomes of dynamic stabilization with DIAM implants.
METHODS
We evaluated 24 cases in which lumbar decompressive surgery was performed with dynamic stabilization using DIAM and having more than 24 months of follow up. Indications consisted of spinal stenosis with or without a herniated disc and transition level stenosis of the instrumented fusion segment. Operative data, clinical outcome, and plain and flexion/extension radiographs were obtained and compared to preoperative and postoperative data.
RESULTS
The mean age at operation was 56.2 years(range 47-68); the mean follow-up duration was 28.4 months(range 24-37 months).The mean pain and function scores improved significantly from baseline to follow-up, as follows: back pain VAS score from 6.2 to 2.5, leg pain VAS score from 7.2 to 2.4, and Prolo's economic and functional rating score from 5.8 to 8.2. Radiological data demonstrated that the heights of the intervertebral foramen and the posterior disc increased significantly after the procedure. There were no implant-associated complications except for two spinous process fractures which occurred during DIAM insertion, and one case of wound infection. Flexion instability and spondylolisthesis occurred in two cases during the follow-up period.
CONCLUSION
These mid-term results suggest that DIAM is a safe and effective alternative surgical option in the treatment of degenerative lumbar stenosis without flexion instability. Careful follow-up is needed to watch for the development of flexion instability and spondylolisthesis.
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Spontaneous Atlantoaxial Subluxation due to Pyogenic or Tuberculosis Vertebral Osteomyelitis: Diagnosis and Treatment.
Korean J Spine. 2010;7(3):131-136.
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Spontaneous Atlantoaxial Subluxation due to Pyogenic or Tuberculosis Vertebral Osteomyelitis: Diagnosis and Treatment.
Korean J Spine. 2010;7(3):131-136.
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OBJECTIVE
The purpose of this study is to evaluate the clinical and radiographic results of infective atlantoaxial subluxation, and to describe the management of pyogenic or tuberculosis atlantoaxial subluxation.
METHODS
In this study, we present seven patients with atlantoaxial subluxation after pyogenic or tuberculosis vertebral osteomyelitis. Prominent manifestations included neck pain and stiffness, swelling of the retropharyngeal soft tissues, quadriparesis, and osteolytic erosions. All patients received antibiotics/antituberculosis medication. One patient was managed conservatively, two underwent only transoral biopsy, one patient underwent transoral decompression and posterior fusion, and three patients underwent only posterior fusion.
RESULTS
All patients showed significant improvement in neck pain and neck movement. Three patients who showed quadriparesis or motor weakness at the time of diagnosis showed improvement in motor strength, although subjective weakness persisted in two patients.
CONCLUSION
In our study, we describe the management of this disease at our institute. Available treatment modalities vary from purely conservative medical management to surgical correction. Medical treatment is the mainstay of management. The need for and the extent of surgery are dependent on the presence of instability and spinal cord compression and should be determined on a case by case basis.
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Review

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Current and Future of Spinal Robot Surgery.
Korean J Spine. 2010;7(2):61-65.
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Current and Future of Spinal Robot Surgery.
Korean J Spine. 2010;7(2):61-65.
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OBJECTIVE
To review the current applications of robotics in spinal surgery.
METHODS
We reviewed the literature on robotic surgery identified by searching Pubmed. Articles reporting clinical results of robotic surgeries using the da Vinci surgical system(R) were analyzed. Descriptions of our trials and comparisons with the conventional techniques were added to the review.
RESULTS
Several surgical robots have been developed however, most of the robots are currently unavailable for practical use. Most of publications regarding spinal surgical robots merely suggested its feasibility. The da vinci surgical system(R) is the popular robotic system designed for use in various surgical fields. However, clinical applications of this innovative instrument in spinal surgery seem to be in the experimental phase. According to our research, the advantages of robotic surgery using the da Vinci surgical system(R) were maximized in cases of paravertebral or presacral tumors however, its use in other types of spinal surgeries such as the transoral craniovertebral junction approach andanterior lumbar interbody fusion will be feasible in the near future despite the current limitations.
CONCLUSION
Clinical application of robotic surgery in the spinal surgical field is currently confined to the treatment of some specific diseases or procedures however, robotic surgery is expected to play a practical future role as a minimally invasive surgical instrument in spinal surgery.
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Original Article

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The Clinical Evaluation of Calcium Phosphate Cement Compared with Polymethylmethacrylate for Kyphoplasty.
Korean J Spine. 2008;5(3):167-172.
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The Clinical Evaluation of Calcium Phosphate Cement Compared with Polymethylmethacrylate for Kyphoplasty.
Korean J Spine. 2008;5(3):167-172.
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OBJECTIVE
We investigated the clinical outcome of kyphoplasty using calcium phosphate (CaP) for vertebral augmentation compared with polymethylmethacrylate (PMMA). We conducted a retrospective study to determine whether patients with osteoporotic vertebral fracture who underwent CaP kyphoplasty had improved outcome in the correction of vertebral body and relief of pain compared with those who underwent PMMA treatment.
METHODS
From January 2005 to December 2006, 117 consecutive patients with osteoporotic compression fracture were treated at our institute. Among them, 23 patients have treated to kyphoplasty using PMMA or CaP. We reviewed the clinical data and imaging studies retrospectively as sources for analysis.
RESULTS
The 23 patients included in the study. A mean ages of CaP and PMMA group were 70+/-9.5 and 67+/-9.5 years respectively. Preoperative compression ratios (CR) were 0.71+/-0.12 and 0.74+/-0.15 on both groups. Postoperative CR, however, showed the difference between two groups. The differences of preoperative and postoperative Cobb`s angle were 10.04 and 2.18 on CaP and PMMA group respectively and the mean injected volume of cement were 3.85+/-1.73 and 4.4+/-1.23 ml.
CONCLUSION
The amount of injected volume of bone cement in kyphoplasty has no difference on both groups. But, follow-up compression ratio and Cobb`s angle are larger in CaP group than PMMA group. However, pain and functional recovery is not different on both group. As a result, CaP can not sufficiently support the strength of vertebral body, but be used to control the acute pain.
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Clinical Trial

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Interspinous Implantation for Degenerative Lumbar Spine: Clinical and Radiological Outcome at 3-yr Follow Up.
Korean J Spine. 2008;5(3):130-135.
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Interspinous Implantation for Degenerative Lumbar Spine: Clinical and Radiological Outcome at 3-yr Follow Up.
Korean J Spine. 2008;5(3):130-135.
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OBJECTIVE
Interspinous devices for dynamic stabilization of lumbar spine are undergoing development and clinical trials. A few short-term outcomes of interspinous devices have been reported but little has been mentioned about longterm outcomes. We reviewed 19 cases of interspinous implantation (Coflex Paradigm spine, Germany) to evaluate clinical long-term outcome and radiologic features.
METHODS
From January 2003 to March 2004, 19 patients (13 female and 6 male) who underwent interspinous implantation were included and follow-up data on clinical and radiologic outcomes were obtained at last clinic visit (mean follow-up: 38 months). Clinical outcomes were assessed by Visual analogue scale (VAS) score and Odom..s criteria.
RESULTS
Preoperative VAS score for low back pain and leg pain was improved from 4.9+/-2.4 and 7.5+/-2.4 to 2.6+/-1.2 and 3.0+/-1.8 respectively at postoperative last clinic visit (p<0.01). Using Odom..s criteria, 7 and 9 patients showed excellent (36.8%) and good (47.3%) results for low back pain and 7 and 11 showed excellent (36.8%) and good (57.9%) results for leg pain. Anterior and posterior disc height were decreased significantly on postoperative follow-up radiologic data due to discectomy at the level of instrumentation (p<0.01). There were no complications such as infection or device failure.
CONCLUSIONS
In this long-term follow-up study, clinical outcome was good but disc degeneration after discectomy at instumented level resulting in decrease of disc height was observed.
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