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"Evan M. Luther"

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"Evan M. Luther"

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Effects of Obesity on Cervical Disc Arthroplasty Complications
Neurospine. 2023;20(4):1399-1406.   Published online December 31, 2023
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Effects of Obesity on Cervical Disc Arthroplasty Complications
Neurospine. 2023;20(4):1399-1406.   Published online December 31, 2023
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Objective
High body mass index is a well-established modifiable comorbidity that is known to increase postoperative complications in all types of surgery, including spine surgery. Obesity is increasing in prevalence amongst the general population. As this growing population of obese patients ages, understanding how they faire undergoing cervical disc arthroplasty (CDA) is important for providing safe and effective evidence-based care for cervical degenerative pathology.
Methods
Our study used the Healthcare Cost and Utilization Project’s National Inpatient Sample to assess patients undergoing CDA comparing patient characteristics and outcomes in nonobese patients to obese patients from 2004 to 2014.
Results
Our study found a significant increase in the overall utilization of CDA as a treatment modality (p = 0.012) and a statistically significant increase in obese patients undergoing CDA (p < 0.0001) from 2004 to 2014. Obesity was identified as an independent risk factor associated with increased rates of inpatient neurologic complications (odds ratio [OR], 6.99; p = 0.03), pulmonary embolus (OR, 5.41; p = 0.05), and wound infection (OR, 6.97; p < 0.001) in patients undergoing CDA from 2004 to 2014.
Conclusion
In patients undergoing CDA, from 2004 to 2014, obesity was identified as an independent risk factor with significantly increased rates of inpatient neurologic complications, pulmonary embolus and wound infection. Large prospective trials are needed to validate these findings.

Citations

Citations to this article as recorded by  Crossref logo
  • Inpatient National Trends and Aggregate Costs of Primary and Revision Lumbar Fusion in the United States from 2016 to 2022
    Mitchell K. Ng, Leonidas E. Mastrokostas, Paul G. Mastrokostas, Yulia Lee, Sean Inzerillo, Jonathan Dalton, Arya Varthi, Jad Bou Monsef, Afshin E. Razi, Jose A. Canseco, Thomas D. Cha, Alan S. Hilibrand, Alexander R. Vaccaro, Gregory D. Schroeder, Christo
    The Spine Journal.2026;[Epub]     CrossRef
  • Cervical disc arthroplasty is safe across various obesity levels
    Manjot Singh, Benjamin Chanes, Mariah Balmaceno-Criss, Alan H. Daniels, Andrew S Zhang
    The Spine Journal.2025; 25(4): 756.     CrossRef
  • Single-level anterior cervical discectomy and fusion is associated with higher nonroutine discharge rates compared to cervical disc arthroplasty in obese patients
    Paul G. Mastrokostas, Luke B. Schwartz, Eli Berglas, Aaron B. Lavi, Leonidas E. Mastrokostas, Jonathan Dalton, Christopher K. Kepler, Arya Varthi, Jad Bou Monsef, Afshin E. Razi, Mitchell K. Ng
    Journal of Craniovertebral Junction and Spine.2025; 16(2): 205.     CrossRef
  • A systematic review of intervertebral disc degeneration clinical trial protocols
    Francis Chemorion, Jerome Noailly, Marc-Antonio Bisotti
    Open Research Europe.2025; 5: 284.     CrossRef
  • Sexual Dimorphism in the Atlas Vertebra of Normal and Overweight Patients with its Possible Surgical Implications
    Nilgün Tuncel Çini, Mathias Orellana-Donoso, Guinevere Granite, Pablo Nova-Baeza, Federico Mata-Escolano, Esther Blanco-Perez, Juan José Valenzuela-Fuenzalida, Maria Piagkou, George Triantafyllou, Marko Konschake, Juan A. Sanchis-Gimeno
    World Neurosurgery.2025; 204: 124531.     CrossRef
  • Biomechanical Analysis of Hybrid Artificial Discs or Zero-Profile Devices for Treating 1-Level Adjacent Segment Degeneration in ACDF Revision Surgery
    Weishi Liang, Yihan Yang, Bo Han, Duan Sun, Peng Yin, Yong Hai
    Neurospine.2024; 21(2): 606.     CrossRef
  • Beyond the Label: Extended Indications for Cervical Disc Arthroplasty
    Annika Bay, Eric R. Zhao, Cole T. Kwas, Chad Z. Simon, Tomoyuki Asada, Sheeraz A. Qureshi
    Contemporary Spine Surgery.2024; 25(12): 1.     CrossRef
  • 5,007 View
  • 197 Download
  • 5 Web of Science
  • 7 Crossref

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National Trends and Correlates of Dysphagia After Anterior Cervical Discectomy and Fusion Surgery
Neurospine. 2021;18(1):147-154.   Published online March 31, 2021
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National Trends and Correlates of Dysphagia After Anterior Cervical Discectomy and Fusion Surgery
Neurospine. 2021;18(1):147-154.   Published online March 31, 2021
Close
Objective
Anterior cervical discectomy and fusion (ACDF) is the most common performed surgery in the cervical spine. Dysphagia is one of the most frequent complications following ACDF. Several studies have identified certain demographic and perioperative risk factors associated with increased dysphagia rates, but few have reported recent trends. Our study aims to report current trends and factors associated with the development of inpatient postoperative dysphagia after ACDF.
Methods
The National Inpatient Sample was evaluated from 2004 to 2014 and discharges with International Classification of Diseases procedure codes indicating ACDF were selected. Time trend series plots were created for the yearly treatment trends for each fusion level by dysphagia outcome. Separate univariable followed by multivariable logistic regression analyses were performed to evaluate predictors of dysphagia.
Results
A total of 1,212,475 ACDFs were identified in which 3.3% experienced postoperative dysphagia. A significant increase in annual dysphagia rates was observed from 2004–2014. Frailty, intraoperative neuromonitoring, 4 or more level fusions, African American race, fluid/electrolyte disorders, blood loss, and coagulopathy were all identified as significant independent risk factors for the development of postoperative dysphagia following ACDF.
Conclusion
Postoperative dysphagia is a well-known postsurgical complication associated with ACDF. Our cohort showed a significant increase in the annual dysphagia rates independent of levels fused. We identified several risk factors associated with the development of postoperative dysphagia after ACDF.

Citations

Citations to this article as recorded by  Crossref logo
  • LASSO-based machine learning algorithm for prediction of dysphagia in patients suffering anterior cervical discectomy and fusion
    Bingyu Wang, Jiawei Shi, Zefu Chen, Jingmin Liu, Yongjian Zhu, Zhongmin Zhang, Xin Zheng, Xiaobo Wang
    European Spine Journal.2026; 35(2): 559.     CrossRef
  • The impact of postoperative drain placement on perioperative management in anterior cervical discectomy and fusion (ACDF)
    Xianxu Zhang, Changlin Zhou, Wenxiang Shen, Lei Huang, Bin Qian, Yuji Zhang, Zhixuan Nian, Rui Li, Shicheng Li, Zhiqiang Luo
    Journal of Clinical Neuroscience.2026; 143: 111768.     CrossRef
  • Cost-effectiveness of early surgical intervention for asymptomatic cervical spinal cord compression:a Markov model analysis
    Mihir S. Dekhne, Tejas Subramanian, Michael Mazzucco, Gregory S. Kazarian, Han Jo Kim, Sravisht Iyer
    The Spine Journal.2026;[Epub]     CrossRef
  • When combined frailty, anemia, and malnourishment exhibit a predictive power for 30-day outcomes following anterior cervical discectomy and fusions for cervical spondylotic myelopathy
    Jacob M. Gluski, Gabrielle Santangelo, Paul Serrato, Shaila Ghanekar, Ethan DL Brown, Aryaa Karkare, Aladine Elsamadicy, Sheng-fu Larry Lo, Daniel M. Sciubba
    Next Research.2026; 5: 101378.     CrossRef
  • Behind the Procedure: Understanding Complications in Anterior Cervical Surgery
    Hussam Abu Nowar , Wesam Khraisat, Mu'taz Halasah, Laith Alomari, Osama Alabadi, Khalid Abu-Rumman
    Cureus.2026;[Epub]     CrossRef
  • National Trends and Risk Factors for Dysphagia After Anterior Cervical Discectomy and Fusion
    Caryn J. Ha, Sraavya G. Anne, Sara Morgan, Fadar Oliver Otite, Kenneth Yan
    The Laryngoscope.2026;[Epub]     CrossRef
  • Bibliometric study of research trends in dysphagia complicating following anterior cervical spine surgery
    Shang Qisong, Xiang Wei, Wu Yuanyuan, Song Xinghua
    Frontiers in Surgery.2025;[Epub]     CrossRef
  • A machine learning-driven model predicts patient-reported dysphagia after instrumented cervical fusion
    Akash A. Shah, Changhee Lee, Amador Bugarin, Sai K. Devana, Alexander Upfill-Brown, Nelson F. SooHoo, Don Y. Park
    Artificial Intelligence Surgery.2025; 5(2): 210.     CrossRef
  • Demand analysis of perioperative nursing service needs for patients with cervical spondylosis based on the Kano model: a cross-sectional study
    LinLing Hu, Lei Wang, Yan Wang, Jing Huang, Ping Dong, Chunmei Luo
    BMC Nursing.2025;[Epub]     CrossRef
  • Evaluating the Effect of Gastroesophageal Reflux Disease on Postoperative Dysphagia Following Anterior Cervical Spine Surgery-A Prospective, Multicenter Study
    Aditya Mazmudar, Taylor Paziuk, John Mangan, Khoa Tran, Samuel Oh, Sandy Li, Brandon Sherrod, Erica Bisson, Darrel Brodke, Christopher Kepler, Gregory Schroeder, Alexander Vaccaro, Alan Hilibrand, Jeffrey A. Rihn
    Global Spine Journal.2024; 14(5): 1595.     CrossRef
  • The efficacy of post-operative drains for anterior cervical discectomy and fusion: a systematic review and meta-analysis
    Aaron Lerch, Anthony Minh Tien Chau
    British Journal of Neurosurgery.2024; 38(1): 3.     CrossRef
  • Impact of Frailty and Cervical Radiographic Parameters on Postoperative Dysphagia Following Anterior Cervical Spine Surgery
    Tomoyuki Asada, Sumedha Singh, Omri Maayan, Pratyush Shahi, Nishtha Singh, Tejas Subramanian, Kasra Araghi, Maximilian Korsun, Olivia Tuma, Anthony Pajak, Amy Lu, Eric Mai, Yeo Eun Kim, James Dowdell, Evan D. Sheha, Sravisht Iyer, Sheeraz A. Qureshi
    Spine.2024; 49(2): 81.     CrossRef
  • The Effect of the Coronavirus Disease 2019 Pandemic on Pituitary Surgery
    Evan Luther, Ian Ramsay, Vaidya Govindarajan, Chandler N. Berke, Vivien Makhoul, Martin Merenzon, Katherine Berry, Alexis Morell, Daniel Eichberg, Victor M. Lu, Ashish Shah, Ricardo J. Komotar, Michael E. Ivan
    World Neurosurgery.2024; 186: e440.     CrossRef
  • Comparison of the efficacy of ROI-C cage with Zero-P device in anterior cervical discectomy and fusion of cervical degenerative disc disease: a two-year follow-up study
    Penghuan Wu, Sifan Yang, Yu Wang, Qiang Wu, Yingze Zhang
    Frontiers in Surgery.2024;[Epub]     CrossRef
  • Frailty as a Superior Predictor of Dysphagia and Surgically Placed Feeding Tube Requirement After Anterior Cervical Discectomy and Fusion Relative to Age
    Alexandria F. Naftchi, John Vellek, Julia Stack, Eris Spirollari, Sima Vazquez, Ankita Das, Jacob D. Greisman, Zehavya Stadlan, Omar H. Tarawneh, Sabrina Zeller, Jose F. Dominguez, Merritt D. Kinon, Chirag D. Gandhi, Syed Faraz Kazim, Meic H. Schmidt, Chr
    Dysphagia.2023; 38(3): 837.     CrossRef
  • Leveraging HFRS to assess how frailty affects healthcare resource utilization after elective ACDF for CSM
    Aladine A. Elsamadicy, Andrew B. Koo, Margot Sarkozy, Wyatt B. David, Benjamin C. Reeves, Saarang Patel, Justice Hansen, Mani Ratnesh S. Sandhu, Astrid C. Hengartner, Andrew Hersh, Luis Kolb, Sheng-Fu Larry Lo, John H. Shin, Ehud Mendel, Daniel M. Sciubba
    The Spine Journal.2023; 23(1): 124.     CrossRef
  • Anterior cervical discectomy and fusion, open-door laminoplasty, or laminectomy with fusion: Which is the better treatment for four-level cervical spondylotic myelopathy?
    Huajian Zhong, Chen Xu, Ruizhe Wang, Xiaodong Wu, Huiqiao Wu, Baifeng Sun, Xinwei Wang, Huajiang Chen, Xiaolong Shen, Wen Yuan
    Frontiers in Surgery.2023;[Epub]     CrossRef
  • Safety and Efficacy of Local Steroid Application on Dysphagia Following Anterior Cervical Discectomy and Fusion
    Jun-wu Wang, Peng-zhi Shi, Kai Li, Lei Zhu, Xin-min Feng, Wen-jie Zhang, Liang Zhang
    Clinical Spine Surgery.2023; 36(7): 265.     CrossRef
  • Nationwide sample data analysis of additional surgery rate after anterior or posterior cervical spinal surgery
    Woon Tak Yuh, Minjung Kim, Yunhee Choi, Junghoon Han, Junhoe Kim, Taeshin Kim, Chun Kee Chung, Chang-Hyun Lee, Sung Bae Park, Kyoung-Tae Kim, John M. Rhee, Moon Soo Park, Chi Heon Kim
    Scientific Reports.2023;[Epub]     CrossRef
  • Standalone versus Anterior Cervical Plating for One-To-Two Level Anterior Cervical Discectomy and Fusion: A Propensity Score-Matched Comparative Study
    Ammad A. Baig, Alexander O. Aguirre, Mohamed A.R. Soliman, Cathleen C. Kuo, Jaims Lim, Asham Khan, Ivette Chen, Kenneth V. Snyder, Elad I. Levy, Adnan H. Siddiqui, John Pollina, Jeffrey P. Mullin
    World Neurosurgery.2023; 177: e673.     CrossRef
  • Comparing zero-profile and conventional cage and plate in anterior cervical discectomy and fusion using finite-element modeling
    Chang-Hwan Ahn, Sungwook Kang, Mingoo Cho, Seong-Hun Kim, Chi Heon Kim, Inbo Han, Chul-Hyun Kim, Sung Hyun Noh, Kyoung-Tae Kim, Jong-Moon Hwang
    Scientific Reports.2023;[Epub]     CrossRef
  • What Type of Incision for Anterior Cervical Spine Surgery Involving Long Segments Can Bring Better Cosmetic and Functional Outcomes?
    Hyung Rae Lee, Dong-Ho Lee, Sang Yun Seok, Sehan Park, Jae Hwan Cho, Chang Ju Hwang, Choon Sung Lee
    Neurospine.2022; 19(2): 412.     CrossRef
  • A Bibliometric Analysis of the Top 100 Cited Articles in Anterior Cervical Discectomy and Fusion
    Xun Wang, Yanze Lin, Qiongtai Wang, Liqing Gao, Fabo Feng
    Journal of Pain Research.2022; Volume 15: 3137.     CrossRef
  • Commentary: Transcondylar Odontoid Resection and Stabilization for Craniovertebral Degenerative Compression: 2-Dimensional Operative Video
    Evan Luther, Gurvinder Kaur, Ricardo Komotar, Michael Ivan
    Operative Neurosurgery.2021; 21(5): E431.     CrossRef
  • Bibliometric and visualized analysis of the top 100 most-cited articles on anterior cervical surgery
    Junbo He, Tingkui Wu, Chen Ding, Beiyu Wang, Ying Hong, Hao Liu
    EFORT Open Reviews.2021; 6(12): 1203.     CrossRef
  • 12,055 View
  • 189 Download
  • 23 Web of Science
  • 25 Crossref