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"Jesse J. Liu"

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Bone Biology and Osteoporosis Special Issue

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Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty
Neurospine. 2023;20(4):1132-1139.   Published online December 31, 2023
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Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty
Neurospine. 2023;20(4):1132-1139.   Published online December 31, 2023
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Objective
The purpose of this study is to examine the utilization of kyphoplasty/vertebroplasty procedures in the management of compression fractures. With the growing elderly population and the associated increase in rates of osteoporosis, vertebral compression fractures have become a daily encounter for spine surgeons. However, there remains a lack of consensus on the optimal management of this patient population.
Methods
A retrospective analysis of 91 million longitudinally followed patients from 2016 to 2019 was performed using the PearlDiver Patient Claims Database. Patients with compression fractures were identified using International Classification of Disease, 10th Revision codes, and a subset of patients who received kyphoplasty/vertebroplasty were identified using Common Procedural Terminology codes. Baseline demographic and clinical data between groups were acquired. Multivariable regression analysis was performed to determine predictors of receiving kyphoplasty/vertebroplasty.
Results
A total of 348,457 patients with compression fractures were identified with 9.2% of patients receiving kyphoplasty/vertebroplasty as their initial treatment. Of these patients, 43.5% underwent additional kyphoplasty/vertebroplasty 30 days after initial intervention. Patients receiving kyphoplasty/vertebroplasty were significantly older (72.2 vs. 67.9, p < 0.05), female, obese, had active smoking status and had higher Elixhauser Comorbidity Index scores. Multivariable analysis demonstrated that female sex, smoking status, and obesity were the 3 strongest predictors of receiving kyphoplasty/vertebroplasty (odds ratio, 1.27, 1.24, and 1.14, respectively). The annual rate of kyphoplasty/vertebroplasty did not change significantly (range, 8%–11%).
Conclusion
The majority of vertebral compression fractures are managed nonoperatively. However, certain patient factors such as smoking status, obesity, female sex, older age, osteoporosis, and greater comorbidities are predictors of undergoing kyphoplasty/vertebroplasty.

Citations

Citations to this article as recorded by  Crossref logo
  • The Effectiveness of Fu’s Subcutaneous Needling for Residual Pain After Percutaneous Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures: A Randomized Clinical Trial Protocol
    Qiong Wang, Zhengqiang Ren, Binru Wang, Juan Du, Xinming Li, Jianjiao Mou
    Journal of Pain Research.2026; Volume 19: 1.     CrossRef
  • Minimally Invasive Treatment Using Biportal Endoscopic Decompression with Vertebroplasty for Osteoporotic Vertebral Compression Fractures in Older Adult Patients
    Sang-Min Park, Sang-Soo Na, Ho-Joong Kim, Jin S. Yeom
    Clinics in Orthopedic Surgery.2025; 17(5): 836.     CrossRef
  • Single-Level Vertebral Augmentation Procedures
    Rahul H. Jayaram, Rohil Malpani, Albert L. Rancu, Philip P. Ratnasamy, Anshu Jonnalagadda, Jonathan N. Grauer
    Clinical Spine Surgery.2025;[Epub]     CrossRef
  • Commentary on “Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty”
    Sahir S. Jabbouri, Peter G. Whang
    Neurospine.2023; 20(4): 1140.     CrossRef
  • From the Editor-in-Chief: Featured Articles in the December 2023 Issue
    Inbo Han
    Neurospine.2023; 20(4): 1093.     CrossRef
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