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"Ki Seok Park"

Clinical Article

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Radiologic Changes of Operated and Adjacent Segments after Anterior Cervical Microforaminotomy
Korean J Spine. 2016;13(3):134-138.   Published online September 30, 2016
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Radiologic Changes of Operated and Adjacent Segments after Anterior Cervical Microforaminotomy
Korean J Spine. 2016;13(3):134-138.   Published online September 30, 2016
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Objective

Anterior cervical microforaminotomy (ACMF) is a motion-preserving surgical procedure. The purpose of this study is to assess radiologic changes of operated and adjacent segments after ACMF.

Methods

We retrospectively reviewed 52 patients who underwent ACMF between 1998 and 2008. From X-ray film-based changes, disc height and sagittal range of motion (ROM) of operated and adjacent segments were compared at preoperative and last follow-up periods. Radiological degeneration of both segments was analyzed as well.

Results

The mean follow-up period was 48.2 months. There were 78 operated, 52 upper adjacent, and 38 lower adjacent segments. There were statistically significant differences in the ROM and disc height of operated segment between preoperative and last follow-up periods. However, there were no statistically significant differences in the ROM and disc height of adjacent segment between both periods. Radiological degenerative changes of operated segments were observed in 30%. That of adjacent segments was observed in 11 and 11% at upper and lower segments, respectively.

Conclusion

After mean 4-year follow-up periods, there were degenerative changes of operated segments. However, ACMF preserved motion and prevented degenerative changes of adjacent segments.

Citations

Citations to this article as recorded by  Crossref logo
  • Clinical and radiological outcomes of anterior cervical foraminotomy: Insights from a pioneering Australian case series and systematic review
    Jiahua Huang, Daniel Liu, Keshan Murugananthan, Saeed Kohan
    Journal of Clinical Neuroscience.2025; 142: 111698.     CrossRef
  • Anterior Endoscopic Cervical Discectomy: Surgical Technique and Literature Review
    Yong Ahn
    Neurospine.2023; 20(1): 11.     CrossRef
  • Long-term Radiological Evidence of Affected and Adjacent Segment Disease after Anterior Cervical Foraminotomy
    Yasufumi OHTAKE, Junya HANAKITA, Toshiyuki TAKAHASHI, Manabu MINAMI, Hirohiko NAKAMURA, Taigo KAWAOKA
    Neurologia medico-chirurgica.2020; 60(10): 492.     CrossRef
  • 9,851 View
  • 110 Download
  • 3 Crossref

Case Report

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Surgical Treatment of Lumbar Hyperextension Injury in Ankylosing Spondylitis
Korean J Spine. 2013;10(3):195-199.   Published online September 30, 2013
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Surgical Treatment of Lumbar Hyperextension Injury in Ankylosing Spondylitis
Korean J Spine. 2013;10(3):195-199.   Published online September 30, 2013
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Ankylosing spondylitis (AS) is a chronic systemic and inflammatory rheumatic disease with a variable course of the axial skeleton. Spinal involvement may accompany ossification of the ligaments, intervertebral disc, end-plates and apophyseal structures, and seems to be "bamboo spine". Because of these natures of the spine in AS, a spinal fracture can be occurred with minor trauma or spontaneously. The fracture of the AS can cause neurological complications extremely high, so special attention to prevent neurological deterioration. Operative management of the injured spine with AS is difficult, and associated with a high complication rate. Extreme care must be taken for surgery to prevent secondary neurological deterioration.

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  • Management of Thoracolumbar Vertebral Fractures and Dislocations in Patients with Ankylosing Conditions of the Spine
    Mohammad Daher, Anna Rezk, Makeen Baroudi, Jerzy Gregorczyk, Mariah Balmaceno Criss, Jake McDermott, Christopher L Mcdonald, Bassel G Diebo, Alan H Daniels
    Orthopedic Reviews.2024;[Epub]     CrossRef
  • Management of cervical fractures in ankylosing spondylitis patients: immediate fixation effort via vertebroplasty with one-staged combined anterior and posterior fixation
    Ming-Fai Tse, Yi-Hsin Tsai, Lin-Hsue Yang, Fu-Shan Jaw, Che-Kuang Lin
    British Journal of Neurosurgery.2023; 37(3): 433.     CrossRef
  • Microalgae and Bacteria Interaction—Evidence for Division of Diligence in the Alga Microbiota
    Yekaterina Astafyeva, Marno Gurschke, Minyue Qi, Lutgardis Bergmann, Daniela Indenbirken, Imke de Grahl, Elena Katzowitsch, Sigrun Reumann, Dieter Hanelt, Malik Alawi, Wolfgang R. Streit, Ines Krohn, Eva C. Sonnenschein
    Microbiology Spectrum.2022;[Epub]     CrossRef
  • Complete Fusion of Three Lumbar Vertebral Bodies in Ankylosing Spondylitis
    Dong Hyun Kim, Seok Won Kim, Sung Myung Lee
    Korean Journal of Neurotrauma.2020;[Epub]     CrossRef
  • Leading a Patient of Ankylosing Spondylitis to Death by Iatrogenic Spinal Fracture
    Jae-Sang Oh, Jae-Won Doh, Jai-Joon Shim, Kyeong-Seok Lee
    Korean Journal of Spine.2016; 13(2): 80.     CrossRef
  • Fractures in Ankylosing Disorders of the Spine: Easy to Miss and High Risk of Deterioration
    David Choi
    World Neurosurgery.2015; 83(6): 1029.     CrossRef
  • 10,468 View
  • 72 Download
  • 6 Crossref

Clinical Article

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The Comparisons of Surgical Outcomes and Clinical Characteristics between the Far Lateral Lumbar Disc Herniations and the Paramedian Lumbar Disc Herniations
Korean J Spine. 2013;10(3):155-159.   Published online September 30, 2013
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The Comparisons of Surgical Outcomes and Clinical Characteristics between the Far Lateral Lumbar Disc Herniations and the Paramedian Lumbar Disc Herniations
Korean J Spine. 2013;10(3):155-159.   Published online September 30, 2013
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Objective

The purpose of this study is to analyze clinical characteristics and surgical outcomes of the far lateral and the paramedian disc herniations.

Methods

The 88 patients who underwent an operation for lumbar disc herniations were reviewed. Visual analogue scale of leg and back pain, occurrence of sensory dysesthesia and motor deficit before and after operations were used to compare the far lateral with the paramedian disc herniations.

Results

Statistically, the far lateral herniations had more severe radicular leg pain and showed more frequent occurrence of sensory dysesthesia than paramedian herniations before operation (p<0.05). In the far lateral herniation group, preoperatively, 15 patients (75%) had sensory dysesthesia and among them, 4 patients (27%) showed improvement. In the paramedian herniation group, preoperatively, 25 patients (37%) had sensory dysesthesia and among them, 21 patients (84%) showed improvement. The degree of improvement in sensory dysesthesia was statistically higher in paramedian herniation group (p<0.05). In the far lateral herniation group, preoperatively, 11 patients (55%) had motor deficit and among them, 10 patients (91%) showed improvement. In the paramedian herniations, preoperatively, 29 patients (43%) had motor deficit and among them, 25 patients (86%) showed improvement. The degree of improvement in motor deficit was not statistically significant between groups (p>0.05).

Conclusion

Preoperatively, the far lateral herniations had more severe radicular leg pain and frequent occurrence of sensory dysesthesia. Postoperatively, the sensory dysesthesia was less improved and back pain was more severe in the far lateral herniations.

Citations

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  • Minimally Invasive Tubular Diskectomy for a Left L4/5 Far Lateral Disk Herniation: 2-Dimensional Operative Video
    Noah Willett, Mousa K. Hamad, Chibuikem A. Ikwuegbuenyi, Roger Härtl
    Operative Neurosurgery.2026; 30(5): 794.     CrossRef
  • MODIFIED PARAMEDIAN APPROACH FOR FAR LATERAL LUMBAR DISC HERNIATION: RETROSPECTIVE ANALYSIS OF A STABILITY-PRESERVING, FACET/PARS-SPARING SERIES
    Ümit Kocaman, Durmuş Oğuz Karakoyun, Emre Çavuşoğlu
    Journal of Turkish Spinal Surgery.2026;[Epub]     CrossRef
  • Extraforaminal versus central lumbar disc herniations: clinical features and surgical outcome comparing data from a national spine registry (NORspine)
    João André Barroso Pereira Roque dos Reis, Greger Lønne, Oliver Grundnes, Ole Kristian Alhaug
    The Spine Journal.2026;[Epub]     CrossRef
  • Transforaminal endoscopic lumbar discectomy versus interlaminar endoscopic lumbar discectomy for lumbar disc herniations: a prospective multicenter study of recovery trajectories using high-frequency patient-reported outcome measures
    Paula K. Krause, Jannik Leyendecker, Cathryn Payne, Nguyen T. Tran, Albert Teilfeian, Peter B. Derman, John Ogunlade, Saqib Hasan, Sanjay Konakondla, Meng Huang, Raymond Joseph Gardocki, Mark Mahan, Imad Khan, Anubhav Amin, Jan Bredow, Christoph P. Hofste
    The Spine Journal.2026; 26(8): 1518.     CrossRef
  • Lumbar Disc Features Predictive of Favorable Response to Transforaminal Epidural Steroid Injection: a Comprehensive Review
    Alexander Kervyn De Volkaersbeke, Sudeep Peddireddy, Gabriel Howard, Behnum Habibi
    Current Pain and Headache Reports.2026;[Epub]     CrossRef
  • Comparing Patient-Reported Outcomes of Lateral to Paramedian Lumbar Disc Herniation: A Propensity Score–Matched Observational Study
    Gustav Østerheden Andersen, Stefan Milosevic, Mads Moss Jensen, Leah Carreon, Casper Friis Pedersen, Mikkel Østerheden Andersen, Peter Helmig
    World Neurosurgery.2025; 195: 123641.     CrossRef
  • Percutaneous endoscopic lumbar discectomy for extreme lateral lumbar disc herniation
    Thomas Luebbers, Albatol Ali, Rainer Baalmann, Aydemir Kale
    Surgical Neurology International.2025; 16: 150.     CrossRef
  • Transforaminal Epidural Injection for Far Lateral Lumbar Disc Herniations: An Alternative to Surgery or Just a Delay?
    Luay Serifoglu, Mustafa U Etli
    Cureus.2024;[Epub]     CrossRef
  • Full-Endoscopic Extraforaminal Approach for Extraforaminal Herniated Intervertebral Disc Disease: Exploring Challenging Case
    Jae Hwan Lee, Kai-Sheng Chang, Li-Wei Sun, Kuo-Tai Chen, Chien-Min Chen
    Journal of Minimally Invasive Spine Surgery and Technique.2024; 9(Suppl 1): S85.     CrossRef
  • Long-term follow-up results of surgically treated patients with foraminal and far lateral disc herniations
    Huseyin Dogu, Nuriye Guzin Ozdemir, Hakan Yilmaz, Ibrahim Burak Atci
    British Journal of Neurosurgery.2023; 37(1): 49.     CrossRef
  • Efficacy of Epidural Steroid Injections and Evaluation of Surgical and Anesthetic Approaches in Far-Lateral Disc Herniations
    Hande Gurbuz, Mehmet Secer, Aykut Gokbel
    Pain Management.2023; 13(2): 95.     CrossRef
  • A Modified Approach for Minimally Invasive Tubular Microdiscectomy for Far Lateral Disc Herniations: Docking at the Caudal Level Transverse Process
    Murray Echt, Adewale Bakare, Richard G. Fessler
    Medicina.2022; 58(5): 640.     CrossRef
  • Clinical Experience on Intertransverse Extraforaminal Approach for Far Lateral Disc Herniations
    A Gökyar, F Tonga
    Nigerian Journal of Clinical Practice.2022; 25(5): 630.     CrossRef
  • Percutaneous Endoscopic Discectomy Via a Transforaminal Approach for L5/S1 Far-Lateral Disc Herniation Assisted by Intraoperative Computed Tomography
    Bing Ran, Rong Chen, Chanchan Song, Yi Li, Jun Wei, JunMing Ye
    World Neurosurgery.2022; 166: e823.     CrossRef
  • Ein extrem lateraler Bandscheibenvorfall L4/5
    Thomas Lübbers, Rainer Baalmann, Gerd Sandvoss
    Die Wirbelsäule.2021; 05(04): 259.     CrossRef
  • The irony of the transforaminal approach
    Yong Ahn, Byung Rhae Yoo, Jong-myung Jung
    Medicine.2021; 100(40): e27412.     CrossRef
  • Comparison of post surgical results in medial and lateral lumbar spine herniated discs: Own case series experience
    Domenico Chirchiglia, Attilio Della Torre, Domenico La Torre
    Interdisciplinary Neurosurgery.2020; 22: 100748.     CrossRef
  • Minimally Invasive, Far Lateral Lumbar Microdiscectomy with Intraoperative Computed Tomography Navigational Assistance and Electrophysiological Monitoring
    Hesham Soliman, Jared Fridley, Albert Telfeian, David B. Choi, Michael Galgano, Thomas Kosztowski, Ziya L. Gokaslan, Adetokunbo A. Oyelese
    World Neurosurgery.2019; 122: e1228.     CrossRef
  • Extraforaminal Lumbar Disk Herniations Lead To Neuroplastic Changes: a Study Using Quantitative Sensory Testing
    Anja Tschugg, Sara Lener, Sebastian Hartmann, Valentin Fink, Sabrina Neururer, Matthias Wildauer, Wolfgang N. Löscher, Claudius Thome
    Muscle & Nerve.2018; 58(5): 676.     CrossRef
  • Five-year outcomes and predictive factors of transforaminal full-endoscopic lumbar discectomy
    Yong Ahn, Uhn Lee, Woo-Kyung Kim, Han Joong Keum
    Medicine.2018; 97(48): e13454.     CrossRef
  • Clinical and Radiological Characteristics of Lumbosacral Lateral Disc Herniation in Comparison With Those of Medial Disc Herniation
    Jung Hwan Lee, Sang-Ho Lee
    Medicine.2016; 95(7): e2733.     CrossRef
  • A Modified Approach of Percutaneous Endoscopic Lumbar Discectomy (PELD) for Far Lateral Disc Herniation at L5-S1 with Foot Drop
    Eun Hee Chun, Hahck Soo Park
    The Korean Journal of Pain.2016; 29(1): 57.     CrossRef
  • 15,176 View
  • 95 Download
  • 22 Crossref

Case Report

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Spontaneous Cervical Epidural Hematoma Causing Brown-Sequard Syndrome
Korean J Spine. 2012;9(3):297-299.   Published online September 30, 2012
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Spontaneous Cervical Epidural Hematoma Causing Brown-Sequard Syndrome
Korean J Spine. 2012;9(3):297-299.   Published online September 30, 2012
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Spontaneous cervical epidural hematoma (SCEH) is a rare clinical entity and has a varied etiology. Urgent surgical decompression should be done to prevent serious permanent neurologic deficits. We describe a 59-year-old female who presented with Brown-Sequard syndrome due to spontaneous cervical epidural hematoma. Initially, she was misdiagnosed as cerebrovascular accident. Cervical magnetic resonance imaging revealed epidural hematoma to the right of the spinal cord extending from C3 to C6. She later underwent surgical evacuation and had complete restoration of neurologic function. The outcome in SCEH is essentially determined by the time taken from onset of the symptom to operation. Therefore, early and precise diagnosis such as careful history taking and MRI evaluation is mandatory.

Citations

Citations to this article as recorded by  Crossref logo
  • Takotsubo Syndrome Following Emergency Decompression for Acute Cervical Spinal Epidural Hematoma: A Case Report
    Kazushi Takayama, Yuko Ono, Isamu Yamada, Joji Kotani
    American Journal of Case Reports.2026;[Epub]     CrossRef
  • Traumatic Cervical Epidural Hematoma without Osseous Fracture Presenting as Hemiparesis
    Hak Soo Lee, Chang Il Ju, Seok Won Kim
    Korean Journal of Neurotrauma.2019; 15(2): 209.     CrossRef
  • Spontaneous cervical epidural hematoma with incomplete Brown-Sequard Syndrome
    Mugurel Radoi, Florin Stefanescu, Ram Vakilnejad, Lidia Gheorghitescu
    Romanian Neurosurgery.2015;[Epub]     CrossRef
  • 8,375 View
  • 83 Download
  • 3 Crossref

Clinical Articles

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Surgical Results and Risk Factors for Recurrence of Lumbar Disc Herniation
Korean J Spine. 2012;9(3):170-175.   Published online September 30, 2012
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Surgical Results and Risk Factors for Recurrence of Lumbar Disc Herniation
Korean J Spine. 2012;9(3):170-175.   Published online September 30, 2012
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Objective

Recurrent lumbar disc herniation has been defined as disc herniation at the same level, regardless of ipsilateral or contralateral herniation, with a pain-free interval greater than 6 months. The aim of this study is to analyze outcomes and identify the potential risk factors for recurrent lumbar disc herniation.

Methods

The authors retrospectively reviewed the cases of 178 patients who underwent open discectomy for single-level lumbar disc herniation. Visual analogue scales and modified Macnab criteria were used to compare the clinical outcomes between the recurrent group and the non-recurrent group.

Sex, age, discectomy level, degree of disc degeneration, type of disc herniation, pain-free interval after first-operation, smoking status, and trauma were investigated as potential recurrence risk factors.

Results

Of the 178 patients for whom the authors were able to definitely assess symptomatic recurrence status, 18 patients (10.1%) underwent revision surgery for recurrent disc herniation. The most common level involved was L4-L5 (61%) and the mean period of time to recurrence was 18.7 months (6-61 months). There were 17 cases of ipsilateral herniation and 1 case of contralateral herniation. The types of herniation for which revision surgery was done were protrusion (3 cases), and transligamentous extrusion (14 cases). There were five excellent, eight good, and two fair results.

Conclusion

Repeated discectomy for recurrent disc herniation produced unsatisfactory outcomes. Factors such as sex, type of disc herniation and traumatic events were found to be significant risk factors.

Citations

Citations to this article as recorded by  Crossref logo
  • Preoperative Clinical and Radiographic Risk Factors for Recurrent Lumbar Disc Herniation: Systematic Review and Meta-analysis
    Mohamed A.R. Soliman, Hendrick Francois, Alexander O. Aguirre, Asham Khan, Waeel Hamouda, Stipe Ćorluka, Zorica Buser, Samuel K. Cho, S. Tim Yoon
    Neurospine.2026; 23(1): 42.     CrossRef
  • Significance of intraoperative induced cough reflex in reducing the incidence of residual and recurrent lumbar disc herniation after microdiscectomy. A prospective cohort study
    Mohamed Samir Abdelhamid, Tarek Anwar Elfiky, Hesham Aly El Saghir, Mahmoud Elsayed Ali Nafady, Yasser Mohamed Ehab Amin Elmansy
    Alexandria Journal of Medicine.2025; 61(1): 171.     CrossRef
  • Patient-Reported Outcomes in Recurrent Lumbar Disc Herniation Surgery: Clinical Results and a Decision-Making Algorithm for Endoscopic Technique Selection
    Xavier Castel, Henri d’Astorg, Thais Dutra Vieira, Marc Szadkowski
    World Neurosurgery.2025; 200: 124207.     CrossRef
  • Hybrid Unilateral Biportal Endoscopy-Unilateral Laminotomy for Bilateral Decompression/Percutaneous Endoscopic Lumbar Discectomy Surgery for the Treatment of Multilevel Lumbar Spine Pathology
    Kang Suk Moon, Pedro Leonardo Villanueva-Solorzano, Chung Nam Lee, Sung Sik Park
    Journal of Minimally Invasive Spine Surgery and Technique.2025; 10(Suppl 2): S306.     CrossRef
  • Practice preference of revision surgery for recurrent lumbar disc herniation: an international survey of AO spine members
    Sathish Muthu, Stipe Corluka, Waeel Hamouda, Luca Ambrosio, Carla Cunha, Stjepan Ivandic, Gianluca Vadala, Hans-Jorg Meisel, Tim S Yoon, Jeffrey C Wang, Amit Jain, Zorica Buser
    European Spine Journal.2025;[Epub]     CrossRef
  • The assessment of the validity, safety, and utility of ChatGPT for patients with herniated lumbar disc: A preliminary study
    Seoyon Yang, Min Cheol Chang
    Medicine.2024; 103(23): e38445.     CrossRef
  • The Impact of Demographic Characteristics, Obesity, Surgical Level, and Intervertebral Disc Properties on Recurrence of Lumbar Disc Herniation
    Güray Bulut, Semra Işık, Mustafa Umut Etli, Cumhur Kaan Yaltırık
    World Neurosurgery.2024; 190: e748.     CrossRef
  • Factors associated with the recurrence of lumbar disk herniation: non-biomechanical–radiological and intraoperative factors
    Anas Abdallah, Betül Güler Abdallah
    Neurological Research.2023; 45(1): 11.     CrossRef
  • Moderate to Severe Multifidus Fatty Atrophy is the Risk Factor for Recurrence After Microdiscectomy of Lumbar Disc Herniation
    Fengzhao Zhu, Dongqing Jia, Yaqing Zhang, Ya Ning, Xue Leng, Chencheng Feng, Changqing Li, Yue Zhou, Bo Huang
    Neurospine.2023; 20(2): 637.     CrossRef
  • How to spot the recurring lumbar disc? Risk factors for recurrent lumbar disc herniation (rLDH) in adult patients with lumbar disc prolapse: a systematic review and meta-analysis
    ABDEL-RAHMAN ABDEL-FATTAH, A IRVING, S BALIGA, P.K. MYINT, K.R. MARTIN
    Acta Orthopaedica Belgica.2023; 89(3): 381.     CrossRef
  • Factors associated with the recurrence of lumbar disk herniation: biomechanical–radiological and demographic factors
    Anas Abdallah, Erhan Emel, Betül Güler Abdallah
    Neurological Research.2022; 44(9): 830.     CrossRef
  • Risk Factors for Recurrence of Disc Herniation After Single-Level Lumbar Discectomy
    Yong Guk Kim, Joo Chul Yang, Tae Wan Kim
    Asian Journal of Pain.2021; 7: 1.     CrossRef
  • Adjuvant surgical decision-making system for lumbar intervertebral disc herniation after percutaneous endoscopic lumber discectomy: a retrospective nonlinear multiple logistic regression prediction model based on a large sample
    Yueyang Li, Bo Wang, Haiyin Li, Xian Chang, Yu Wu, Zhilei Hu, Chenhao Liu, Xiaoxin Gao, Yuyao Zhang, Huan Liu, Yongming Li, Changqing Li
    The Spine Journal.2021; 21(12): 2035.     CrossRef
  • Development of a two-part biomaterial adhesive strategy for annulus fibrosus repair and ex vivo evaluation of implant herniation risk
    Tyler J. DiStefano, Jennifer O. Shmukler, George Danias, Theodor Di Pauli von Treuheim, Warren W. Hom, David A. Goldberg, Damien M. Laudier, Philip R. Nasser, Andrew C. Hecht, Steven B. Nicoll, James C. Iatridis
    Biomaterials.2020; 258: 120309.     CrossRef
  • Risk Factors of Secondary Lumbar Discectomy of a Herniated Lumbar Disc after Lumbar Discectomy
    Joo Yul Beack, Hyoung Joon Chun, Koang Hum Bak, Kyu-Sun Choi, In-Suk Bae, Kee D. Kim
    Journal of Korean Neurosurgical Society.2019; 62(5): 586.     CrossRef
  • Smoking Is an Independent Risk Factor of Reoperation Due to Recurrent Lumbar Disc Herniation
    Stina Brogård Andersen, Elisabeth Corydon Smith, Christian Støttrup, Leah Y. Carreon, Mikkel O. Andersen
    Global Spine Journal.2018; 8(4): 378.     CrossRef
  • Long‐Term Course to Lumbar Disc Resorption Patients and Predictive Factors Associated with Disc Resorption
    Jinho Lee, Joowon Kim, Joon-Shik Shin, Yoon Jae Lee, Me-riong Kim, Seon-Yeong Jeong, Young-jun Choi, Tae Kyung Yoon, Byung-heon Moon, Su-bin Yoo, Jungsoo Hong, In-Hyuk Ha, Gihyun Lee
    Evidence-Based Complementary and Alternative Medicine.2017;[Epub]     CrossRef
  • Biportal Endoscopic Spinal Surgery for Recurrent Lumbar Disc Herniations
    Dae-Jung Choi, Je-Tea Jung, Sang-Jin Lee, Young-Sang Kim, Han-Jin Jang, Bang Yoo
    Clinics in Orthopedic Surgery.2016; 8(3): 325.     CrossRef
  • 23,501 View
  • 144 Download
  • 18 Crossref

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An Early Comparative Analysis of the Use of Autograft Versus Allograft in Anterior Cervical Discectomy and Fusion
Korean J Spine. 2012;9(3):142-146.   Published online September 30, 2012
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An Early Comparative Analysis of the Use of Autograft Versus Allograft in Anterior Cervical Discectomy and Fusion
Korean J Spine. 2012;9(3):142-146.   Published online September 30, 2012
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Objective

The purpose of this study is to verify the usefulness of autograft versus allograft in the radiographic and clinical outcome in early period after the surgery.

Methods

We performed a retrospective review of 38 patients who had undergone one- or two-level anterior cervical discectomy and fusion (ACDF) with rigid anterior plate fixation from March 2006 to May 2009. Interbody graft materials were iliac autograft (n=17) or with allograft (n=21). Fusion rate and graft collapse rate were assessed by radiographic analysis and clinical outcome was based on Odom's criteria.

Results

In autograft group, 13 patients achieved successful bone fusion (65%), whereas 7 patients (31.8%) in allograft group. There was statistically significant between two groups (p<0.05). Comparing immediate postoperative radiograph with last follow-up, the mean graft collapse was noted 1.3mm(15.5% change) in autograft group, whereas 2.0mm(24.7% change) in allograft group. There was no statistically significant collapse rate in autograft group (p>0.05), but statistically significant in allograft group (p<0.05). Clinical outcome was excellent or good in 94.1% in autograft group, and 90.5% in allograft group.

Conclusion

In study, anterior cervical interbody fusion with an allograft got a result of lower fusion rate and higher collapse rate compared with autograft in early period after surgery, and clinical outcome showed similar results in both groups.

Citations

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  • An innovative advance in bone grafting: initial clinical results using a novel integrative bone graft in spinal fusion
    Peter G. Passias, Oluwatobi O. Onafowokan, Ankita Das, Jamshaid M. Mir, Anthony Yung, Max Fisher
    Frontiers in Musculoskeletal Disorders.2025;[Epub]     CrossRef
  • Comparison of Different Osteobiologics in Terms of Imaging Modalities and Time Frames for Fusion Assessment in Anterior Cervical Discectomy and Fusion: A Systematic Review
    Andrew S. Chung, Robert Ravinsky, Ronit Kulkarni, Patrick C. Hsieh, Jacobus J. Arts, Ricardo Rodrigues-Pinto, Jeffrey C. Wang, Hans Jörg Meisel, Zorica Buser
    Global Spine Journal.2024; 14(2_suppl): 141.     CrossRef
  • Porous Cage Macro-Topography Improves Early Fusion Rates in Anterior Cervical Discectomy and Fusion
    Gregory M. Malham, Dean T. Biddau, Jordan P. Laggoune, Charlie R. Faulks, William R. Walsh, Yi Yuen Wang, Imtiaz Wani
    Surgery Research and Practice.2024; 2024: 1.     CrossRef
  • Combining Bone Collagen Material with hUC-MSCs for Applicationto Spina Bifida in a Rabbit Model
    Hu Wang, Xue-Cheng Sun, Jian-Hui Li, Li-Qiang Yin, Yu-Fang Yan, Xu Ma, Hong-Fei Xia
    Stem Cell Reviews and Reports.2023; 19(4): 1034.     CrossRef
  • 12-Month clinical and radiographic outcomes of ViBone viable bone matrix in patients undergoing cervical and lumbar spinal fusion surgery
    Paul D. Kim, Ramin Raiszadeh, David A. Bomback, David L. Kramer, Michael Moghimi
    Journal of Orthopaedic Surgery and Research.2023;[Epub]     CrossRef
  • Active bone material containing modified recombinant human bone morphogenetic protein-2 induces bone regeneration in rabbit spina bifida
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Original Articles

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Technical Strategies and Surgical Results of C1 Lateral Mass-C2 Pedicular Screw Fixation in Atlantoaxial Disorders.
Korean J Spine. 2008;5(3):196-202.
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Technical Strategies and Surgical Results of C1 Lateral Mass-C2 Pedicular Screw Fixation in Atlantoaxial Disorders.
Korean J Spine. 2008;5(3):196-202.
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OBJECTIVE
There are various posterior fusion techniques in managing C1-2 instability. The aim of this study is to evaluate surgical techniques and clinical results including complications of the C1 lateral mass and C2 pedicle screw fixation (C1-2 LMPSF) in atlantoaxial disorders.
METHODS
From February 1997 to July 2008, 24 patients were performed C1-2 LMPSF due to C1-2 instability. Pathway of vertebral artery was classified into three groups by 3D-angiogram. Diameter of C1 lateral mass and C2 isthmus on the plain X-ray and CT was measured before operation. Surgical method was divided into four groups according to fixation site (bilateral or unilateral) and bone graft (with or without graft). Stability of C1-2 fixation was postoperatively evaluated by flexion and extension cervical lateral films. We reviewed clinical data, imaging studies and old chart retrospectively as sources for analysis.
RESULTS
Among 24 patients, os odontoideum was the most common cause (16 out of 24). Four patients had anomalous vertebral artery. Mean diameters of C1 lateral mass was 9.9(range 4.2~16.4) mm at right side, 10.3 (range 3.4~14.2) mm at left side. Mean diameter of C2 isthmus was 5.8 (range 1.0~10.1) mm at right side and 5.8(range 2.1~8.2) mm at left side. Two patients showed very narrow C2 isthmus. As a result, unilateral C1-2 LMPSF was performed on 6 patients (4 for anomalous vertebral arteries and 2 for narrow C2 isthmus). 12 of 18 patients were with C1-2 interlaminar bone graft and 6 patients without bone graft. All patients showed stable C1-2 fixation by flexion and extension cervical lateral X-ray films taken at least 6 months after surgery. Five out of 8 patients who had preoperative radiculopathy only showed improved symptoms. However, Seven out of 8 patients who had myelopathy showed little neurological improvement .
CONCLUSION
For C1-2 LMPSF, preoperative 3D CT-angiogram study is mandatory to identify abnormal vertebral artery and narrow C2 isthmus. Bilateral C1-2 LMPSF without bone graft is enough to obtain stable C1-2 fixation. If there is an abnormal vertebral artery or narrow C2 isthmus, unilateral C1-2 LMPSF with bone graft and wiring is alternative successful method.
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Long Term Clinical and Radiographic Results of Lumbar Spinal Stenosis with Grade I Degenerative Spondylolisthesis after Microsurgical Bilateral Decompression via Unilateral Laminotomy.
Korean J Spine. 2009;6(3):169-174.
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Long Term Clinical and Radiographic Results of Lumbar Spinal Stenosis with Grade I Degenerative Spondylolisthesis after Microsurgical Bilateral Decompression via Unilateral Laminotomy.
Korean J Spine. 2009;6(3):169-174.
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OBJECTIVE
The purpose of this study was to assess long-term clinical outcomes and radiographic changes in patients with lumbar spinal stenosis with grade I degenerative spondylolisthesis who underwent microsurgical bilateral decompression via unilateral laminotomy, as a minimally invasive surgery.
Method
Medical records of twenty-five patients who underwent the surgery between 1999 and 2005 were retrospectively evaluated. Clinical outcomes were evaluated through interviews over telephone with standardized questionnaires. Preoperative and postoperative radiographs were taken from all patients in neutral and dynamic lateral views. The mean follow-up period after surgery was 38.5 months(range 9-57 months).
RESULTS
Seventy-two percent of patients were either pain free(48%) or doing well with occasional acetaminophens(24 %), and satisfied with the treatment. The most improved preoperative symptom was neurogenic intermittent claudication, which was ameliorated in 94.7% of patients(excellent 84.2%, good 10.5%, fair 5.3%). Postoperative vertebral slippage was also measured and appeared to be slightly increased but this was not statistically significant. Postoperative dynamic angulation did not change significantly compared to the preoperative value.
CONCLUSION
Microsurgical bilateral decompression via unilateral laminotomy achieved a satisfactory decompression and symptomatic relief without extensive destruction of the weight-bearing structures and functional mobile segments. This treatment can be an effective modality for patients with lumbar spinal stenosis associated with mild degenerative spondylolisthesis.
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Long-term Follow-up Results of Anterior Cervical Microforaminotomy.
Korean J Spine. 2010;7(2):66-72.
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Long-term Follow-up Results of Anterior Cervical Microforaminotomy.
Korean J Spine. 2010;7(2):66-72.
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OBJECTIVE
We previously reported excellent early and midterm clinical results of anterior cervical microforaminotomy (ACMF) for patients with cervical radiculopathy caused by disc herniation or foraminal stenosis. ACMF is accepted as a minimally invasive functional spinal surgery, but its long-term outcomes are unknown. The purpose of this study is to evaluate the long-term clinical and radiographic results of ACMF.
METHODS
We performed a questionnaire survey and retrospective analysis of 13 patients with cervical radiculopathy who underwent ACMF from 1998 to 2002. Clinical and radiographic data from these 13 patients (one-level operations in seven patients, and two-level operations in six patients) were analysed. We measured disc height, sagittal plane displacement and sagittal plane angulation to evaluate instability.
RESULTS
Thirteen patients answered the questionnaires. Mean follow-up was 77.3 months (ranged from 498 to 110 months). The surgical outcome was excellent in three patients (23%) and good in nine patients (69%). One patient had only a fair outcome, but there were no cases of recurrence, reoperation or additional surgery. Twelve of 13 patients were satisfied with the results of their surgery. On the average, the loss of disc height was 0.84mm(16.6% of preoperative disc height), increase of displacement was 0.47mm and increase of sagittal plane angulation was 0.65degrees. All patients maintained stability during the follow-up period. Although the patient sample included in this study is a different sample from that surveyed in our previous study of mid-term results, the long-term radiographic outcomes showed that the parameters of instability tended to decrease in comparison to those midterm results. Three-dimensional computed tomography scans showed signs indicative of bone remodeling, including regrowth of the resected bone and gradual fusion around the uncovertebral joint (UVJ) where ACMF was performed. In spite of bone regeneration around the UVJ, the neural foramen appeared to be well maintained in all patients.
CONCLUSION
In the long-term, ACMF is clinically effective method for the treatment of cervical radiculopathy, although disc height was decreased and sagittal angulation was increased. UVJ with mild hypermobility that was apparent at midterm appears to be restored during long-term follow-up. The efficacy of this procedure should be evaluated in additional studies involving large patient series.
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Surgical Treatment of Degenerative Lumbar Spine Disease in Geriatric Patients Over 70 Years Old: A Review of Two Decades.
Korean J Spine. 2008;5(3):161-166.
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Surgical Treatment of Degenerative Lumbar Spine Disease in Geriatric Patients Over 70 Years Old: A Review of Two Decades.
Korean J Spine. 2008;5(3):161-166.
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OBJECTIVE
The aim of this study is to evaluate the transition of lumbar spinal treatments for geriatric patients over 70 years old over two decades.
METHODS
We retrospectively assessed 730 patients who were 70 years and older and underwent lumbar surgery. We analyzed the number of diseases, operation methods and complications with 5-year intervals from 1987 to 2006. RESULT: The number of patients older than 70 years who underwent lumbar surgery increased according to our analysis of the period spanning from 1987 to 2006. Thirty-two (1%), 77 (1.7%), 232 (4.4%), and 389 (8.2%) patients over 70 years underwent lumbar spine surgeries. Among them, the 8, 29 and 45 patients had one level degenerative spondylolisthesis for the periods 1992-1996, 1997-2001 and 2002-2006. Twenty-four, 29 and 58 patients had lumbar stenosis during all these time periods. Over time, we performed a larger variety of operations as well as more aggressive operations. From January 2002 to December 2006, a total of 308 patients were over 70 years old and had lumbar spine surgeries performed on them. Among them, the ASA class I was 58 (19%), the ASA class II was 213 (69%) and the ASA class III was 37 (12%). During that period, PLIFs and PS fixations were performed on 69 patients. Among them, 8 patients were ASA III. Large numbers of lumbar arthorodesis have been performed in geriatric patients over the age of 70 years in our series.
CONCLUSION
The surgical treatment of degenerative spine disease in the elderly patients was increased due to improved surgical technique and advances in medical treatment including anesthesia. The authors suggest that fusion surgery can be done safely in elderly patients even though they have high-grade ASA classification.
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