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"Manabu Minami"

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"Manabu Minami"

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Bone Biology and Osteoporosis Special Issue

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Therapeutic Prediction of Osteoporotic Vertebral Compression Fracture Using the AO Spine-DGOU Osteoporotic Fracture Classification and Classification-Based Score: A Single-Center Retrospective Observational Study
Neurospine. 2023;20(4):1166-1176.   Published online December 31, 2023
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Therapeutic Prediction of Osteoporotic Vertebral Compression Fracture Using the AO Spine-DGOU Osteoporotic Fracture Classification and Classification-Based Score: A Single-Center Retrospective Observational Study
Neurospine. 2023;20(4):1166-1176.   Published online December 31, 2023
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Objective
The treatment of osteoporotic vertebral compression fractures (OVCFs) is based on their severity; however, an efficient prediction tool is lacking. We aimed to evaluate the validity of the osteoporotic fracture classification (OF classification) and scoring system (OF score) in predicting the treatment strategy for patients with OVCF, defined according to the Japanese criteria.
Methods
We retrospectively investigated 487 consecutive patients diagnosed with vertebral body fractures between January 2018 and December 2022. Only patients with their fresh vertebral fracture episode during the study period were included. Patients were classified into 3 groups: conservative treatment, balloon kyphoplasty (BKP), and open surgery. OF classification and OF scores were assessed for each patient.
Results
A total of 237 patients with OVCF were included. There were 127, 81, and 29 patients in the conservative, BKP, and open surgery groups, respectively. The OF score was significantly higher in the BKP and open surgery groups than in the conservative group (p < 0.001). Multivariate logistic regression analysis showed that antiosteoporotic drug use, OF classification, progressive deformity, neurological symptoms and mobilization were independent risk factors for operative treatment (all p < 0.001). Receiver operating characteristic analysis showed that the cutoff OF score for operative indication was 5.5, with a sensitivity of 91.9%, specificity of 56.5%, and area under the curve of 0.820 (95% confidence interval, 0.769–0.871).
Conclusion
The OF score identified patients who required operative treatment with a high degree of accuracy. This is especially important for ruling out patients who definitely require operative treatment.

Citations

Citations to this article as recorded by  Crossref logo
  • Effect of Kyphoplasty on Pain Control and Vertebral Restoration
    Mustafa C. Kilinc, Baran C. Alpergin, Omer M. Ozpiskin, Eray S. Aktan, Ihsan Dogan
    Journal of Neurological Surgery Part A: Central European Neurosurgery.2026; 87(01): 032.     CrossRef
  • Diagnosis and treatment of osteoporotic vertebral fractures
    Martin Bibza, Michal Božík, Mário Malina, Boris Šteňo
    Clinical Osteology.2026; 31(1): 55.     CrossRef
  • Surgical Considerations in Osteoporotic Dorso-Lumbar Spine Fractures
    Ram Chaddha, Gaurav Agrawal, Agnivesh Tikoo, Harsh Kotadia
    Indian Journal of Orthopaedics.2025; 59(3): 368.     CrossRef
  • Efficacy and safety of erector spinae plane block for the treatment of osteoporotic vertebral compressive fractures
    Yinghong Ma
    American Journal of Translational Research.2025; 17(3): 2023.     CrossRef
  • Classification of Osteoporotic Vertebral Compression Fractures – Current Updates and How to Manage Them
    Aditya Kasture, Abhay Nene, Priyank Patel
    Indian Spine Journal.2025; 8(2): 109.     CrossRef
  • Assessing the Role of Expandable Vertebral Augmentation versus High-Viscosity Cement Vertebroplasty in Severe Osteoporotic Vertebral Fracture Management: A Prospective Cohort Study
    Yi-Chen Liu, You-Rui Lin, Sung Huang Laurent Tsai, Ying-Chih Wang, Chia-Wei Chang, Tung-Yi Lin, Tsai-Sheng Fu, Wen-Jer Chen
    World Neurosurgery.2025; 200: 124166.     CrossRef
  • Robotisch assistierte und minimal-invasive Pedikelschraubenplatzierung an der Lendenwirbelsäule
    Dominik M. Haida, Oybek Khakimov, Stefan Huber-Wagner
    Die Unfallchirurgie.2025; 128(8): 637.     CrossRef
  • OF-score for osteoporotic thoracolumbar fractures– which parameter is decisive for the therapy decision? - a prospective multicentric cohort study
    Bernhard Wilhelm Ullrich, Philipp Schenk, Michael A. Scherer, Michael Müller, Georg Osterhoff, Gregor Schmeiser, Max J. Scheyerer, Ulrich J. Spiegl, Falko Schwarz, Alexander Franck, Volker Zimmermann, Martin Bäumlein, Sebastian Katscher, Klaus Schnake, Wo
    European Spine Journal.2025; 34(11): 5045.     CrossRef
  • Promotion of Bone Formation in a Rat Osteoporotic Vertebral Body Defect Model via Suppression of Osteoclastogenesis by Ectopic Embryonic Calvaria Derived Mesenchymal Stem Cells
    Yerin Yu, Somin Lee, Minsung Bock, Seong Bae An, Hae Eun Shin, Jong Seop Rim, Jun-oh Kwon, Kwang-Sook Park, Inbo Han
    International Journal of Molecular Sciences.2024; 25(15): 8174.     CrossRef
  • A Comparative Analysis of International Classification Systems to Predict the Risk of Collapse in Single-Level Osteoporotic Vertebral Fractures
    Antonio Jesús Láinez Ramos-Bossini, Paula María Jiménez Gutiérrez, David Luengo Gómez, Mario Rivera Izquierdo, José Manuel Benítez, Fernando Ruiz Santiago
    Diagnostics.2024; 14(19): 2152.     CrossRef
  • Successful Treatment of Secondary L5 Osteoporotic Vertebral Fracture Post-balloon Kyphoplasty With Revision Balloon Kyphoplasty
    Keita Kuraishi, Yoshinori Maki, Yoshihiko Ioroi, Tamaki Kobayashi
    Cureus.2024;[Epub]     CrossRef
  • A computed tomography–based morphometric analysis of thoracic pedicles in a European population
    Alberto Alfieri Zellner, Christian Prangenberg, Jonas Roos, Soufian Ben Amar, Tamara Babasiz, Christopher Wahlers, Peer Eysel, Johannes Oppermann
    Journal of Orthopaedic Surgery and Research.2024;[Epub]     CrossRef
  • The value of quantitative analysis of radionuclide bone SPECT/CT imaging in vertebral compression fracture: a retrospective study
    Yuhua Wang, Feifei Qiao, Na Li, Ye Liu, Yahong Long, Kang Xu, Jiantao Wang, Wanchun Zhang
    BMC Medical Imaging.2024;[Epub]     CrossRef
  • Using Key Predictors in an SVM Model for Differentiating Spinal Fractures and Herniated Intervertebral Discs in Preoperative Anesthesia Evaluation
    Shih-Ying Yang, Shih-Yen Hsu, Yi-Kai Su, Nan-Han Lu, Kuo-Ying Liu, Tai-Been Chen, Kon-Ning Chiu, Yung-Hui Huang, Li-Ren Yeh
    Diagnostics.2024; 14(21): 2456.     CrossRef
  • 13,819 View
  • 528 Download
  • 14 Web of Science
  • 14 Crossref

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Improvement in Neurogenic Bowel and Bladder Dysfunction Following Posterior Decompression Surgery for Cauda Equina Syndrome: A Prospective Cohort Study
Neurospine. 2021;18(4):847-853.   Published online December 31, 2021
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Improvement in Neurogenic Bowel and Bladder Dysfunction Following Posterior Decompression Surgery for Cauda Equina Syndrome: A Prospective Cohort Study
Neurospine. 2021;18(4):847-853.   Published online December 31, 2021
Close
Objective
The mechanisms of neurogenic bowel dysfunction (NBD) and neurogenic bladder (NB), which are major consequences of spinal cord injury and occasionally degenerative lumbar disease. The following in patients with cauda equina syndrome who underwent posterior decompression surgery was investigated: (1) the preoperative prevalence of NBD and NB, measured using the Constipation Scoring System (CSS) and International Prostate Symptoms Score (IPSS); (2) the degree and timing of postoperative improvement of NBD and NB.
Methods
We administered the CSS and IPSS in 93 patients before surgery and at 1, 3, 6, and 12 months postoperatively. We prospectively examined patient characteristics, Japanese Orthopaedic Association (JOA) score, and postoperative improvements in each score.
Results
The prevalence of symptomatic defecation and urinary symptoms at admission were 37 patients (38.1%) and 31 patients (33.3%), respectively. Among the symptomatic patients with defecation problems, 12 patients had improved at 1 month, 13 at 3 months, 14 at 6 months, and 13 at 12 months postoperatively. Among the symptomatic patients with urinary problems, 5 patients improved at 1 month, 11 at 3 months, 6 at 6 months, and 10 at 1 year postoperatively. Comparing patients with improved versus unimproved in CSS, the degree of JOA score improvement was a significant prognosis factor (p < 0.05; odds ratio, 1.05).
Conclusion
The prevalence of symptomatic defecation and urinary symptoms in patients with cauda equina syndrome was 38.1% and 33.3%, respectively. Decompression surgery improved symptoms in 30%–50%. These effects were first observed 1 month after the operation and persisted up to 1 year.

Citations

Citations to this article as recorded by  Crossref logo
  • Spinal metastases: modern diagnostics, multimodal treatment approaches, and long-term outcomes
    Anvar F. Nazarov, Rail A. Karaguzin, Danil I. Khalilov, Nadir B. Akhmerov, Elena N. Volkova, Kamila A. Baiguvatova
    Russian Journal of Oncology.2026;[Epub]     CrossRef
  • Analysis of Neurogenic Bowel and Bladder Dysfunction Following Decompression Surgery for Cervical Spondylotic Myelopathy: A Prospective Cohort Study
    Ryo Kanematsu, Junya Hanakita, Tomoo Inoue, Manabu Minami, Izumi Suda, Sho Nakamura, Manabu Ueno, Toshiyuki Takahashi
    Global Spine Journal.2025; 15(2): 587.     CrossRef
  • Efficacy and safety of transcutaneous electrical nerve stimulation combined with clean intermittent catheterization for neurogenic bladder dysfunction in patients with cauda equina syndrome
    Xia Wu, Jinlian Huang, Dexian Wu, Guohui Kang, Kuo Li
    International Urology and Nephrology.2025; 57(10): 3227.     CrossRef
  • Urinary complaints and voiding function in patients operated for lumbar spinal stenosis
    Bjørn Hjall, Sigurd Liavaag, Hans Thorvild Thomassen, Tor Brommeland
    Clinical Neurology and Neurosurgery.2025; 257: 109060.     CrossRef
  • Clinical assessment and management of lumbar spinal stenosis: clinical dilemmas and considerations for surgical referral
    David B Anderson, David J Beard, Francois Rannou, David J Hunter, Pradeep Suri, Lingxiao Chen, James M Van Gelder
    The Lancet Rheumatology.2024; 6(10): e727.     CrossRef
  • How to assess the long-term recovery outcomes of patients with cauda equina syndrome before surgery: a retrospective cohort study
    Qiushi Wang, Guangdong Hou, Mengyuan Wen, Zhongwu Ren, Wei Duan, Xin Lei, Zhou Yao, Shixian Zhao, Bin Ye, Zhipeng Tu, Peipei Huang, Fang Xie, Bo Gao, Xueyu Hu, Zhuojing Luo
    International Journal of Surgery.2024; 110(7): 4197.     CrossRef
  • A CASE REPORT ON LONG TERM COMPLICATIONS OF CAUDA EQUINA SYNDROME
    Shone Padinjarethil George, Shiby Sara Shaji, Mohan Varghese
    INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH.2023; : 60.     CrossRef
  • Application of rectal balloon ice water stimulation for the rehabilitation of stroke patients with neurogenic bowel dysfunction
    Di Zhang, Hong Tang, Ting Li, Ping Li, Xiangying Pan, Qin Jia, Lu Wang, Yanjun Zhao
    NeuroRehabilitation.2023; 53(1): 83.     CrossRef
  • Effect of systemic lidocaine on postoperative quality of recovery, the gastrointestinal function, inflammatory cytokines of lumbar spinal stenosis surgery: a randomized trial
    Yu Wu, Zhuoming Chen, Caimiao Yao, Houxin Sun, Hongxia Li, Xuyang Du, Jianzheng Cheng, Xiaojian Wan
    Scientific Reports.2023;[Epub]     CrossRef
  • Technical feasibility of combined uniportal unilateral laminotomy with bilateral decompression and interlaminar lumbar discectomy surgery for cauda equina syndrome due to lower lumbar disc herniation
    Wu Pang Hung, Rohit Akshay Kavishwar, Hyeun Sung Kim, Brian Zhao Jie Chin
    North American Spine Society Journal (NASSJ).2023; 16: 100290.     CrossRef
  • 16,928 View
  • 152 Download
  • 9 Web of Science
  • 10 Crossref

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Cervical Spondylotic Amyotrophy: Case Series and Review of the Literature
Neurospine. 2019;16(3):579-588.   Published online September 30, 2019
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Cervical Spondylotic Amyotrophy: Case Series and Review of the Literature
Neurospine. 2019;16(3):579-588.   Published online September 30, 2019
Close
Objective
Cervical spondylotic amyotrophy (CSA) is a relatively rare entity caused by cervical degenerative spinal diseases and characterized by motor weakness accompanied by remarkable muscle atrophy in the upper extremities without significant sensory deficits or spastic paraparesis in the lower extremities. Postoperative outcomes and predictive prognostic factors vary among previous reports. In the present report, we describe the surgical results in patients who were surgically treated for CSA and present a literature review.
Methods
In total, 33 patients with CSA were retrospectively analyzed. Correlations between the surgical outcome and the following factors were statistically analyzed: age, sex, type of impaired muscle, preoperative severity of motor weakness, number of levels of cord or root compression, presence of a T2 high-intensity area in the spinal cord, cervical kyphosis, and methods of surgical procedure.
Results
On postoperative neurological evaluation, 25 patients (75.8%) had favorable outcomes and 8 had unfavorable outcomes (proximal type, 72.2%; distal type, 78.6%). Patients with favorable outcomes were significantly younger than those with unfavorable outcomes (p=0.013). Patient’s characteristics except for age and radiological factors were not correlated to surgical outcome.
Conclusion
The present study focused on the surgical results in patients who were surgically treated for CSA along with updated information from a literature review. Improvement of motor weakness is expected with acceptable prevalence although higher age can be a negative factor. Surgical outcomes and predictive factors related to a poor prognosis were determined and compared with those of previous articles.

Citations

Citations to this article as recorded by  Crossref logo
  • Die neuralgische Schulteramyotrophie
    Nenad Mitrovic, Gregor Kienbacher
    rheuma plus.2025; 24(1): 46.     CrossRef
  • The correlation between facet tropism and motor dysfunction of the upper limbs in patients with cervical spondylotic amyotrophy: an observational study
    Yuhang Ji, Kaiwen Chen, Shenyan Gu, Yu Zhu, Feizhou Lyu, Jianyuan Jiang, Xinlei Xia, ChaoJun Zheng
    European Spine Journal.2025; 34(8): 3196.     CrossRef
  • Pathophysiology and Diagnosis of Neuralgic Amyotrophy
    Dong Gyu Lee
    Clinical Pain.2025; 24(2): 127.     CrossRef
  • Surgical Outcomes of Full Endoscopic Posterior Cervical Foraminotomy for Proximal Cervical Spondylotic Amyotrophy
    Deokcheol Lee, Kazuo Ohmori, Reiko Yoneyama, Takuro Endo, Yasuhiro Endo
    Asian Spine Journal.2024; 18(1): 32.     CrossRef
  • Die neuralgische Schulteramyotrophie
    Nenad Mitrovic, Gregor Kienbacher
    Schmerz Nachrichten.2024; 24(2): 72.     CrossRef
  • Paraspinal Muscle Morphology in Proximal Cervical Spondylotic Amyotrophy
    Ryosuke Hirota, Hiroyuki Takashima, Makoto Emori, Tsuneo Takebayashi, Atsushi Teramoto
    Cureus.2024;[Epub]     CrossRef
  • Recent advances in neuroanatomy: the myotome update
    Masahiro Sonoo
    Journal of Neurology, Neurosurgery & Psychiatry.2023; 94(8): 643.     CrossRef
  • Cervical Spondylotic Amyotrophy Initially Misdiagnosed as Amyotrophic Lateral Sclerosis
    Zhong Yu, Haofuzi Zhang, Yanjun Wang
    World Neurosurgery.2023; 180: 3.     CrossRef
  • Description of Clinical Features and Diagnoses of 444 Cases with Neck-Shoulder-Upper Extremity Pain: A Single-Center Retrospective Review
    Hongchao Zhang, Wenqi Luo, Chaoyuan Li, Jianhui Zhao, Qiao Zhang, Rui Gu
    Journal of Pain Research.2022; Volume 15: 3483.     CrossRef
  • Neuralgic Amyotrophy: Its Importance in Orthopedics Practice
    George Fagundes Firmino, Milena Luisa Schulze, Marco Antônio Machado Schlindwein, Breno Rampeloti, Marcus Vinicius Magno Gonçalves, Carlos Henrique Maçaneiro, Ricardo Acácio dos Santos
    Spine Surgery and Related Research.2021; 5(4): 232.     CrossRef
  • A partial least squares analysis of functional status, disability, and quality of life after surgical decompression for degenerative cervical myelopathy
    Jetan H. Badhiwala, Omar Khan, Adam Wegner, Fan Jiang, Jamie R. F. Wilson, Benjamin R. Morgan, George M. Ibrahim, Jefferson R. Wilson, Michael G. Fehlings
    Scientific Reports.2020;[Epub]     CrossRef
  • Atypical Proximal Cervical Spondylotic Amyotrophy: Case Report Demonstrating Clinical/Imaging Discrepancy


    Shitong Feng, Zihan Fan, Yong Yang, Qi Fei, Xiang Li
    International Journal of General Medicine.2020; Volume 13: 1367.     CrossRef
  • A Case of Cervical Spondylotic Amyotrophy Mimicking Amyotrophic Lateral Sclerosis
    Pretty Sara Idiculla, Raghav Govindarajan
    Case Reports in Neurology.2020; 12(3): 314.     CrossRef
  • 15,860 View
  • 336 Download
  • 9 Web of Science
  • 13 Crossref

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Morphological Patterns of the Anterior Median Fissure in the Cervical Spinal Cord Evaluated by Computed Tomography After Myelography
Neurospine. 2018;15(4):388-393.   Published online September 4, 2018
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Morphological Patterns of the Anterior Median Fissure in the Cervical Spinal Cord Evaluated by Computed Tomography After Myelography
Neurospine. 2018;15(4):388-393.   Published online September 4, 2018
Close
Objective
Computed tomography following myelography (CTM) revealed an unusual flow of contrast dye into the anterior median fissure (AMF) in a patient with cervical spondylotic myelopathy. Since then, several AMF configurations have been observed on CTM. Therefore, we evaluated morphological patterns of the AMF on CTM and investigated the significance and mechanisms of contrast dye flow into the AMF.
Methods
Morphological patterns of the AMF on CTM were examined in 79 patients. Group A (24 patients) underwent surgery because of symptomatic cervical myelopathy. Group B (43 patients) had no clinical symptoms but showed spinal cord compression on CTM. Group C (12 patients), who showed neither clinical symptoms nor cord changes, underwent CTM for lumbar lesion evaluation. AMF patterns were classified into 4 types according to their configurations on CTM (reversed T, Y, V, and O types).
Results
In group B, the reversed T type and Y type appeared significantly more often near the compressed portion (p<0.001). A similar tendency was seen in group A. The V and O types were most frequently observed in group C (p<0.001).
Conclusion
On CTM, contrast dye tends to flow into the AMF of the cervical cord when the spinal cord is compressed. We speculate that there may be 3 possible mechanisms for this phenomenon: deformation of the epipial layer of the AMF due to cervical cord compression, AMF dilatation due to atrophy of the anterior funiculus or anterior horn, and temporary AMF dilatation when it becomes an alternative route for cerebrospinal fluid circulation.

Citations

Citations to this article as recorded by  Crossref logo
  • MRI T2-Hyperintense Signal Structures in the Cervical Spinal Cord: Anterior Median Fissure versus Central Canal in Chiari and Control—An Exploratory Pilot Analysis
    T.A. Tomsick, L.L. Wang, M. Zuccarello, A.J. Ringer
    American Journal of Neuroradiology.2021; 42(4): 801.     CrossRef
  • Anatomical disposition of the anterior spinal artery and vein: Subpial or subarachnoid?
    Katsuhiro Mizutani, Georges Rodesch
    Interventional Neuroradiology.2020; 26(6): 706.     CrossRef
  • 11,374 View
  • 255 Download
  • 2 Web of Science
  • 2 Crossref