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Special Issue on AI & Robotics

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Robotic-Assisted Spine Surgery: Role in Training the Next Generation of Spine Surgeons
Neurospine. 2024;21(1):116-127.   Published online March 31, 2024
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Robotic-Assisted Spine Surgery: Role in Training the Next Generation of Spine Surgeons
Neurospine. 2024;21(1):116-127.   Published online March 31, 2024
Close
Objective
This study aimed to assess the degree of interest in robot-assisted spine surgery (RASS) among residents and to investigate the learning curve for beginners performing robotic surgery.
Methods
We conducted a survey to assess awareness and interest in RASS among young neurosurgery residents. Subsequently, we offered a hands-on training program using a dummy to educate one resident. After completing the program, the trained resident performed spinal fusion surgery with robotic assistance under the supervision of a mentor. The clinical outcomes and learning curve associated with robotic surgery were then analyzed.
Results
Neurosurgical residents had limited opportunities to participate in spinal surgery during their training. Despite this, there was a significant interest in the emerging field of robotic surgery. A trained resident performed RASS under the supervision of a senior surgeon. A total of 166 screw insertions were attempted in 28 patients, with 2 screws failing due to skiving. According to the Gertzbein-Robbins classification, 85.54% of the screws were rated as grade A, 11.58% as grade B, 0.6% as grade C, and 1.2% as grade D. The clinical acceptance rate was approximately 96.99%, which is comparable to the results reported by senior experts and time per screw statistically significantly decreased as experience was gained.
Conclusion
RASS can be performed with high accuracy within a relatively short timeframe, if residents receive adequate training.

Citations

Citations to this article as recorded by  Crossref logo
  • Spinale Robotik vs. Cone-Beam-Navigation
    Patrick Strube, Alexander Hölzl, Anna-Maria Vogel, Georg Matziolis, Chris Lindemann
    Die Orthopädie.2026;[Epub]     CrossRef
  • A Comprehensive Review of the Role of the Latest Minimally Invasive Neurosurgery Techniques and Outcomes for Brain and Spinal Surgeries
    Simone Laguardia, Alessio Piccioni, Jorge Eduardo Alonso Vera, Ali Muqaddas, Milko Garcés, Sidra Ambreen, Sarmishtha Sharma, Tara Sabzvari
    Cureus.2025;[Epub]     CrossRef
  • Visuohaptic Feedback in Robotic-Assisted Spine Surgery for Pedicle Screw Placement
    Giuseppe Loggia, Fedan Avrumova, Darren R. Lebl
    Journal of Clinical Medicine.2025; 14(11): 3804.     CrossRef
  • Robot-assisted versus navigated spinal fusion surgery: a comparative multicenter study on transpedicular screw placement accuracy and patient outcomes
    Giada Garufi, Gianluca Scalia, Francesca Graziano, Roberta Costanzo, Massimiliano Porzio, Giancarlo Ponzo, Massimiliano Giuffrida, Giuseppe Ricciardo, Giuseppe Emmanuele Umana, Giovanni Federico Nicoletti, Salvatore Massimiliano Cardali
    Neurosurgical Review.2025;[Epub]     CrossRef
  • Evolving Paradigms in Spine Surgery Training: Integrating Technology, Ethics, and Minimally Invasive Techniques
    G. Balamurali, Soma Sundar Subramanian, Keerthivasan Panneerselvam
    Journal of Minimally Invasive Spine Surgery and Technique.2025; 10(Suppl 2): S107.     CrossRef
  • Robot-Assisted Pedicle Screw Insertion in Pediatric Spine Surgery: An Institutional Experience and Meta-Analysis
    Taha Khalilullah, Abdul Karim Ghaith, Xinlan Yang, Linda Tang, Shaan Bhandarkar, Meghana Bhimreddy, Arjun D. Menta, Daniel Davidar, Andrew Hersh, Carly Weber-Levine, Kelly Jiang, Patrick Kramer, Ritvik Jillala, Maria Jennings, Jawad M. Khalifeh, Tej D. Az
    Operative Neurosurgery.2025;[Epub]     CrossRef
  • Commentary on “The Utility and Feasibility of Smart Glasses in Spine Surgery: Minimizing Radiation Exposure During Percutaneous Pedicle Screw Insertion”
    Wongthawat Liawrungrueang
    Neurospine.2024; 21(2): 440.     CrossRef
  • 8,946 View
  • 176 Download
  • 6 Web of Science
  • 7 Crossref

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Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion
Neurospine. 2023;20(2):553-563.   Published online June 30, 2023
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Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion
Neurospine. 2023;20(2):553-563.   Published online June 30, 2023
Close
Objective
Conventional oblique lumbar interbody fusion (OLIF) approach is possible from the L2/3 to L4/5 levels. However, obstruction of the lower ribs (10th–12th) makes it difficult to maintain disc parallel maneuvers or orthogonal maneuvers. To overcome these limitations, we proposed an intercostal retroperitoneal (ICRP) approach to access the upper lumbar spine. This method does not expose the parietal pleura or require rib resection and employs a small incision.
Methods
We enrolled patients who underwent a lateral interbody procedure on the upper lumbar spine (L1/2/3). We compared the incidence of endplate injury between conventional OLIF and ICRP approaches. In addition, by measuring the rib line, the difference in endplate injury according to rib location and approach was analyzed. We also analyzed the previous period (2018–2021) and the year 2022, when the ICRP has been actively applied.
Results
A total of 121 patients underwent lateral interbody fusion to the upper lumbar spine (OLIF approach, 99 patients; ICRP approach, 22 patients). Endplate injuries occurred in 34 of 99 (34.3%) and 2 of 22 patients (9.1%) during the conventional and ICRP approaches, respectively (p = 0.037; odds ratio, 5.23). When the rib line was located at the L2/3 disc or L3 body, the endplate injury rate was 52.6% (20 of 38) for the OLIF approach but 15.4% (2 of 13) for the ICRP approach. Since 2022, the proportion of OLIF including L1/2/3 levels has increased 2.9-fold.
Conclusion
The ICRP approach is effective in reducing the incidence of endplate injury in patients with a relatively lower rib line, without pleural exposure or rib resection.

Citations

Citations to this article as recorded by  Crossref logo
  • Clinical Characterization of Lymphatic Leakage Complicating OLIF Surgery
    Hanli Yang, Dan Zhang, Wenjie Zhang, Man Luo, Liwei Wang, Yuanming Zhong, Ming Shi
    Clinical Spine Surgery.2026; 39(1): 1.     CrossRef
  • The Minimally Invasive Intercostal Subdiaphragmatic Access without Rib Resection for Lateral Lumbar Interbody Fusion at L1/2: Surgical Techniques and Cases Illustration
    Teerachat Tanasansomboon, Jerry Robinson, Wicharn Yingsakmongkol, Worawat Limthongkul, Weerasak Singhatanadgige, Vit Kotheeranurak, Piyanat Wangsawatwong, Babak Khandehroo, Neel Anand
    World Neurosurgery.2025; 194: 123564.     CrossRef
  • How to choose rib resection in minimally invasive lateral approach thoracolumbar junction corpectomy: radiographic analysis and case illustrations
    Fengyu Liu, Zhenfang Gu, Xianze Sun, Xianzhong Meng
    Frontiers in Surgery.2025;[Epub]     CrossRef
  • Anterior-to-psoas OLIF: Surgical approach, issues & technical nuances
    Stjepan Ivandić, Jure Pavešić, Stipe Ćorluka, Tomislav Čengić
    Seminars in Spine Surgery.2025; 37(1): 101159.     CrossRef
  • L2/3, L3/4 and L4/5 oblique lumbar interbody fusion/anterior to psoas: Anatomical and technical considerations
    Prashanth J Rao, Nipun Shreshtha, Gayani Petersingham, Andrew J Berg, Kevin Seex
    Seminars in Spine Surgery.2025; 37(1): 101162.     CrossRef
  • Radiological Outcomes and Approach-Related Complications in Oblique Lateral Interbody Fusion at the Upper Lumbar Level
    Hee-Woong Chung, Han-Dong Lee, Myungsub Lee, Nam-Su Chung
    Journal of Clinical Medicine.2025; 14(10): 3333.     CrossRef
  • Prediction of Angle Loss after L4/5 Oblique Lumbar Interbody Fusion : Development of a Risk Stratification Model
    Se-Woon Kim, Su-Hun Lee, Jun-Seok Lee, Chi-Hyung Lee, Chang-Hyun Kim, Soon-Ki Sung, Dong-Wuk Son, Sang-Weon Lee
    Journal of Korean Neurosurgical Society.2025; 68(6): 724.     CrossRef
  • A Comprehensive Analysis of Potential Complications after Oblique Lumbar Interbody Fusion : A Review of Postoperative Magnetic Resonance Scans in Over 400 Cases
    Kang-Hoon Lee, Su-Hun Lee, Jun-Seok Lee, Young-Ha Kim, Soon-Ki Sung, Dong-Wuk Son, Sang-Weon Lee, Geun-Sung Song
    Journal of Korean Neurosurgical Society.2024; 67(5): 550.     CrossRef
  • Commentary on “Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion”
    Alexander E. Ropper
    Neurospine.2023; 20(2): 564.     CrossRef
  • From the Editor-in-Chief: Featured Articles in the June 2023 Issue
    Inbo Han
    Neurospine.2023; 20(2): 413.     CrossRef
  • 6,754 View
  • 243 Download
  • 8 Web of Science
  • 10 Crossref

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Relationship Between Endplate Defects, Modic Change, Facet Joint Degeneration, and Disc Degeneration of Cervical Spine
Neurospine. 2020;17(2):443-452.   Published online June 30, 2020
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Relationship Between Endplate Defects, Modic Change, Facet Joint Degeneration, and Disc Degeneration of Cervical Spine
Neurospine. 2020;17(2):443-452.   Published online June 30, 2020
Close
Objective
The ‘‘disc degeneration precedes facet joint osteoarthritis’’ hypothesis and multidimensional analysis were actively discussed in lumbar spine. However, in cervical spine degeneration, the multifactorial analyzes of disc degeneration (DD), Modic changes (Mcs), facet degeneration, and endplate degeneration (ED) is still limited. In this cross-sectional study, we aimed to analyze the prevalence and interrelationship of cervical DD parameters.
Methods
We retrospectively recruited 62 patients aged between 60 and 70 years. The disc height, segmental angle, ossified posterior longitudinal ligament (OPLL), ED, facet joint degeneration (FD), uncovertebral joint degeneration (UD), DD, spinal stenosis (SS), Mc, and cord signal change (CS) were evaluated using a previously well-known grading system.
Results
The prevalence of cervical degenerative parameters were DD (grade 1, 1.2%; grade 2, 13.3%; grade 3, 54.8%; grade 4, 19.0%; grade 5, 11.7%), OPLL (26.2%), SS (grade 0, 7.7%; grade 1, 42.3%; grade 2, 26.2%; grade 3, 23.8%), UD (39.1%), ED (normal, 69.0%; focal defect, 9.7%; corner defect, 11.7%; erosion, 6.9%; sclerosis, 2.8%), and FD (normal, 48.8%; narrowing, 27.0%; hypertrophied, 24.2%). The interrelationship of degenerative parameters showed close relation between UD, SS, DD, OPLL, Mc. ED, and CS has partial relation with degenerative finding. FD only has relation with UD, and Mc.
Conclusion
Our results may indicate that FD is a degeneration that occurs independently, rather than as a result of other degenerative factors.

Citations

Citations to this article as recorded by  Crossref logo
  • Bone tunnel approach for cervical spondylotic radiculopathy with uncovertebral osteophytes
    Xin Wang, Tao Hu, Bo Lei, Chaofan Qin, Xiang Tan, Changjun Pi, Mingxin Chen, Qingshuai Yu, Si Cheng, Zhengjian Yan
    European Spine Journal.2026; 35(4): 1848.     CrossRef
  • Radiological Factors Affecting Cage Subsidence after Single-level Anterior Cervical Discectomy and Fusion with Double Titanium Cylindrical Cages
    Toshiyuki OKAZAKI, Kazuma DOI, Kazunori SHIBAMOTO, Satoshi TANI, Junichi MIZUNO
    Neurologia medico-chirurgica.2026; 66(1): 7.     CrossRef
  • Deep or Superficial? Autologous Conditioned Serum for Cervical Pain with Degenerative Disc Disease – a Randomized Controlled Trial
    Piotr Godek, Małgorzata Paprocka-Borowicz, Kuba Ptaszkowski
    Journal of Pain Research.2026; Volume 19: 1.     CrossRef
  • Does Baseline Facet Arthropathy Influence Early Clinical and Radiographic Outcomes After Cervical Disc Replacement?
    Fatima N. Anwar, James W. Nie, Vincent P. Federico, Andrea M. Roca, Srinath S. Medakkar, Alexandra C. Loya, Gregory D. Lopez, Arash J. Sayari, Kern Singh
    Neurosurgery.2025; 96(1): 87.     CrossRef
  • Lower C2 slope and milder uncovertebral joint degeneration are risk factors for pseudarthrosis after single-level anterior cervical corpectomy and fusion (ACCF): retrospective study of 102 patients with minimum 2-year follow-up
    Haoxiang Wang, Tian Xia, Ruomu Qu, Hanbo Geng, Yu Sun, Fengshan Zhang, Shengfa Pan, Xin Chen, Yanbin Zhao, Feifei Zhou
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Identification of aging-related biomarkers for intervertebral disc degeneration in whole blood samples based on bioinformatics and machine learning
    Zi-hang Li, Shi-pian Li, Ya-hao Li, Yu-cheng Wang, Zhen-yu Tang, Kai-yang Xu, Xiao-rong Li, Zhen Tan, Jiao-yi Pan, Jin-tao Liu, Hong Jiang, Zhi-jia Ma, Yu-xiang Dai, Peng-fei Yu
    Frontiers in Immunology.2025;[Epub]     CrossRef
  • Osteoporosis in adjacent cervical segments exacerbates disc herniation
    Beiyang Wang, Yang Liu, Zhiqiang Wang, Chenguang Niu, Jian Tang, Lin Sun
    Scientific Reports.2025;[Epub]     CrossRef
  • What Cervical MRI Findings Can Tell About ACDF Outcomes and Risks of ASD
    Olga Leonova, Evgenii Baykov, Aleksandr Krutko
    Clinical Spine Surgery.2025;[Epub]     CrossRef
  • Prediction of Angle Loss after L4/5 Oblique Lumbar Interbody Fusion : Development of a Risk Stratification Model
    Se-Woon Kim, Su-Hun Lee, Jun-Seok Lee, Chi-Hyung Lee, Chang-Hyun Kim, Soon-Ki Sung, Dong-Wuk Son, Sang-Weon Lee
    Journal of Korean Neurosurgical Society.2025; 68(6): 724.     CrossRef
  • Intervertebral vacuum phenomenon – prevalence and severity CT-scan analysis in patients older than 50 years: a retrospective cohort study
    Gaston Camino-Willhuber, Santiago Vildoza, Ezequiel Martinez, Lucia Canestrari, Fernando Holc, Michael Oh, Nitin Bhatia, Yu-Po Lee, Homero Bianchi, Mariana Bendersky
    Acta Radiologica.2024; 65(1): 56.     CrossRef
  • Novel Risk Factors for Cervical Facet Joint Degeneration in the Subaxial Cervical Spine: Correlation with Cervical Sagittal Alignment and Bone Mineral Density
    Yuliang Wu, Bo Sun, Zhengqi Huang, Weitao Han, Wanli Zheng, Chao Zhang, Shun Han, Shuangxing Li, Bo Gao, Wei Ye
    World Neurosurgery.2024; 185: e850.     CrossRef
  • Exploration of the correlation between facet joints cross-sectional area asymmetry and cervical disc herniation
    Weijie Yu, Xinyu Wan, Yihan Zhang, Xianlong Yue, Mengxian Jia, Minghang Chen, Jiaxin Lai, Guoting Xu, Honglin Teng
    European Spine Journal.2024; 33(8): 3008.     CrossRef
  • The Prediction of Neurological Prognosis for Cervical Spondylotic Myelopathy Using Diffusion Tensor Imaging
    Soichiro Takamiya, Motoyuki Iwasaki, Takumi Yokohama, Daisuke Oura, Yoshimasa Niiya, Miki Fujimura
    Neurospine.2023; 20(1): 248.     CrossRef
  • Facet Articular Irregularity Is the Most Relevant Risk Factor for Rapidly Progressive Degenerative Cervical Myelopathy
    Yasuhiro Takeshima, Ai Okamoto, Shohei Yokoyama, Fumihiko Nishimura, Ichiro Nakagawa, Young-Soo Park, Hiroyuki Nakase
    Neurospine.2023; 20(1): 365.     CrossRef
  • Comparative study of outcomes between allograft intervertebral disc transplantation and anterior cervical discectomy and fusion: a retrospective cohort study at least 5 years of follow-up
    Junyou Zhang, Dike Ruan, Anwu Xuan, Qing He, Chao Zhang, Cheng Xu, Chao Zhu, Qing Zhou
    European Spine Journal.2023; 32(10): 3561.     CrossRef
  • Comparing zero-profile and conventional cage and plate in anterior cervical discectomy and fusion using finite-element modeling
    Chang-Hwan Ahn, Sungwook Kang, Mingoo Cho, Seong-Hun Kim, Chi Heon Kim, Inbo Han, Chul-Hyun Kim, Sung Hyun Noh, Kyoung-Tae Kim, Jong-Moon Hwang
    Scientific Reports.2023;[Epub]     CrossRef
  • Degenerative changes in the intervertebral joints of the cervical spine after anterior interbody fusion and intervertebral disc arthroplasty
    Aleksandr Sergeyevich Eliseev, Andrey Evgenyevich Bokov, Sergey Gennadyevich Mlyavykh
    Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika).2023; 20(3): 72.     CrossRef
  • Prevalence and Clinical Impact of Cervical Facet Joint Degeneration on Degenerative Cervical Myelopathy: A Novel Computed Tomography Classification Study
    Ai Okamoto, Yasuhiro Takeshima, Shohei Yokoyama, Fumihiko Nishimura, Ichiro Nakagawa, Young-Soo Park, Hiroyuki Nakase
    Neurospine.2022; 19(2): 393.     CrossRef
  • Non-surgical therapy for the treatment of chronic low back pain in patients with Modic changes: A systematic review of the literature
    Xiaoping Mu, Wei Peng, Yufu Ou, Peifeng Li, Zhuhai Li, Jianxun Wei
    Heliyon.2022; 8(7): e09658.     CrossRef
  • Biomechanical Effect of Disc Height on the Components of the Lumbar Column at the Same Axial Load: A Finite-Element Study
    Jae-Gyeong Jeong, Sungwook Kang, Gu-Hee Jung, Mingoo Cho, Hyunsoo Kim, Kyoung-Tae Kim, Dong-Hee Kim, Jong-Moon Hwang, V. E. Sathishkumar
    Journal of Healthcare Engineering.2022; 2022: 1.     CrossRef
  • Examination of the microstructures of the lower cervical facet based on micro-computed tomography: A cadaver study
    Kun Li, Yucheng Ji, Jun Shi, Shaojie Zhang, Haoyu Song, Peng Wang, Chunying Ma, Yansong Zhang, Yexing Dang, Yuan Ma, Xing Wang, Zhijun Li
    Medicine.2022; 101(50): e31805.     CrossRef
  • Cervical Disc Degeneration and Vertebral Endplate Defects After the Fused Operation
    Olga Leonova, Evgenii Baykov, Abdugafur Sanginov, Aleksandr Krutko
    Spine.2021; 46(18): 1234.     CrossRef
  • The CT assessment of uncovertebral joints degeneration in a healthy population
    Tianji Huang, Jie Qin, Weiyang Zhong, Ke Tang, Zhengxue Quan
    European Journal of Medical Research.2021;[Epub]     CrossRef
  • The effect of preoperative degenerative spondylolisthesis on postoperative outcomes of degenerative lumbar spinal stenosis
    Yueliang Chang, Fubiao Zhou, Le Fei, Zili Wang
    Medicine.2020; 99(45): e22355.     CrossRef
  • 12,880 View
  • 338 Download
  • 24 Web of Science
  • 24 Crossref

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Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
Neurospine. 2020;17(1):156-163.   Published online July 5, 2019
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Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
Neurospine. 2020;17(1):156-163.   Published online July 5, 2019
Close
Objective
Anterior cervical discectomy and fusion (ACDF) is the most commonly performed procedure for degenerative cervical spondylosis. Because of its relatively low invasiveness and surgical procedure, old age is not regarded as an exclusion criterion for ACDF. However, very few studies have been conducted on the radiological and clinical outcomes of ACDF in older patients. The purpose of this study was to evaluate the radiological and clinical outcomes of ACDF in older patients.
Methods
We retrospectively analyzed 48 patients (> 65 years) who underwent ACDF from January 2011 to December 2015. We divided the patients into 2 groups: young-old age group (65–74 years) and middle-old age group (≥ 75 years). Cervical lateral radiographs taken in the neutral standing position were evaluated preoperatively (PRE), on postoperative day 7 (POST), and at the 1-year follow-up (F/U). The radiological parameters included cervical angle (CA: C2–7 Cobb angle), segmental angle, total intervertebral height, disc height, sagittal vertical axis (SVA), T1 slope (T1s), and range of cervical motion (extension CA minus flexion CA). Postoperative hospital days, comorbidities, complications, and clinical outcomes were also analyzed.
Results
We analyzed data from 48 patients (group A: n = 30 patients, 46 segments, mean age, 68.60 ± 3.36 years; group B: n = 18 patients, 23 segments, mean age, 79.22 ± 2.63 years). The surgical levels were as follows: C3/4, 4; C4/5, 7; C5/6, 10; C6/7, 29; and C7/ T1, 6 levels, and there were no significant between-group differences in the distribution. There were no significant between-group differences in the fusion and subsidence rates (fusion rate: group A, 76.2%; group B, 71.4%; p = 0.732; subsidence rate: group A, 34.8%; group B, 26.1%; p = 0.587). There was no longitudinal trend in the repeated-measurements analysis of variance test of the 2 groups of the PRE, POST, and F/U data for each radiological parameter. According to the paired t-test, T1 slope (T1s), SVA, and CA did not differ preoperatively and postoperatively. There was no statistically significant difference in visual analogue scale scores (axial, arm), the Neck Disability Index, or Odom’s criteria between the 2 groups (p = 0.448, p = 0.357, and p = 0.913).
Conclusion
There was no significant difference in radiological and clinical outcomes between young-old and middle-old patients. Middle-old age does not seem to be a limitation to ACDF, but larger-scale and longer-term studies are needed to confirm the findings of this study.

Citations

Citations to this article as recorded by  Crossref logo
  • Impact of enhanced recovery after surgery (ERAS) protocols in elderly patients undergoing lumbar fusion: a systematic review with meta-analysis and trial sequential analysis
    Yantong Zhang, Gang Chen, Mengting Xu, Huiqing Gao, Renji Zheng, Wenqin Lv, Zhiping Yin, Yingfeng Zhou, Jun Li, Shaowu Jin
    European Spine Journal.2026; 35(4): 2001.     CrossRef
  • Radiological Factors Affecting Cage Subsidence after Single-level Anterior Cervical Discectomy and Fusion with Double Titanium Cylindrical Cages
    Toshiyuki OKAZAKI, Kazuma DOI, Kazunori SHIBAMOTO, Satoshi TANI, Junichi MIZUNO
    Neurologia medico-chirurgica.2026; 66(1): 7.     CrossRef
  • Predictors of Surgical Outcome After Anterior Cervical Discectomy and Fusion: A Prospective Middle Eastern Cohort Study
    Ahmed Al-Atraqchi, Rawan Alatraqchi, Yasoob A Alaameri
    Cureus.2026;[Epub]     CrossRef
  • Does Back Pain Improve Following Lumbar Decompression Alone?
    David J. Mazur-Hart, Christian G. Lopez Ramos, Joseph G. Nugent, Brannan E. O’Neill, Barry Cheaney, Hanne A. Gehling, Jamila Godil, Brandi W. Pang, Arilene Novak, James T. Obayashi, Travis C. Philipp, Clifford Lin, Jung U. Yoo, Christina H. Wright, James
    Clinical Spine Surgery.2025;[Epub]     CrossRef
  • Surgical management of spinal pathologies in the octogenarian: a narrative review
    Alexander R. Evans, Joshua Bakhsheshian, Christopher S. Graffeo, Zachary A. Smith
    GeroScience.2024; 46(4): 3555.     CrossRef
  • Impact of age within younger populations on outcomes following cervical surgery in the ambulatory setting
    Timothy J. Hartman, James W. Nie, Hanna Pawlowski, Michael C. Prabhu, Nisheka N. Vanjani, Kern Singh
    Journal of Clinical Orthopaedics and Trauma.2022; 34: 102016.     CrossRef
  • Sagittal balance of the cervical spine: a systematic review and meta-analysis
    Parisa Azimi, Taravat Yazdanian, Edward C. Benzel, Yong Hai, Ali Montazeri
    European Spine Journal.2021; 30(6): 1411.     CrossRef
  • Predictors associated with neurological recovery after anterior decompression with fusion for degenerative cervical myelopathy
    Hiroyuki Inose, Takashi Hirai, Toshitaka Yoshii, Atsushi Kimura, Katsushi Takeshita, Hirokazu Inoue, Asato Maekawa, Kenji Endo, Takeo Furuya, Akira Nakamura, Kanji Mori, Shunsuke Kanbara, Shiro Imagama, Shoji Seki, Shunji Matsunaga, Kunihiko Takahashi, At
    BMC Surgery.2021;[Epub]     CrossRef
  • Efficacy for Whitlockite for Augmenting Spinal Fusion
    Su Yeon Kwon, Jung Hee Shim, Yu Ha Kim, Chang Su Lim, Seong Bae An, Inbo Han
    International Journal of Molecular Sciences.2021; 22(23): 12875.     CrossRef
  • Commentary on “Surgical and Functional Outcomes of Expansive Open-Door Laminoplasty for Patients With Mild Kyphotic Cervical Alignment”
    Dongwuk Son
    Neurospine.2021; 18(4): 758.     CrossRef
  • 13,092 View
  • 246 Download
  • 8 Web of Science
  • 10 Crossref

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Differences in Cervical Sagittal Alignment Changes in Patients Undergoing Laminoplasty and Anterior Cervical Discectomy and Fusion
Neurospine. 2018;15(1):91-100.   Published online March 28, 2018
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Differences in Cervical Sagittal Alignment Changes in Patients Undergoing Laminoplasty and Anterior Cervical Discectomy and Fusion
Neurospine. 2018;15(1):91-100.   Published online March 28, 2018
Close
Objective
Anterior cervical discectomy and fusion (ACDF) and laminoplasty (LP) are the most commonly performed procedures for degenerative cervical spondylosis. Cervical sagittal alignment (CSA) has recently been studied as an important predictor of clinical and radiological outcomes. The data from previous studies are insufficient for analysis using the recently designed CSA parameters, T1 slope (T1s), and T1s minus cervical angle (T1sCA).
Methods
We retrospectively collected data from patients who underwent ACDF and LP from January 2013 to May 2016. The CSA parameters included CA, sagittal vertical axis, T1s, and T1sCA. T1sCA values were used to evaluate the preoperative cervical balance (T1sCA>20°: imbalance). Clinical results were evaluated using the neck disability index (NDI) and recovery rate (RR) according to the Japanese Orthopedic Association scoring system.
Results
We analyzed the data of 72 patients (ACDF, n=39; LP, n=33). Imbalance on ACDF was associated with an increase in CA (balance: preoperative [PRE], 15.64° → follow-up [F/U], 15.74°, p=0.953; imbalance: PRE, −1.14° → F/U, 8.045°, p=0.008), whereas balance on LP was associated with a significant decrease in CA (balance: PRE, 16.26°→ F/U, 11.59°, p=0.009; imbalance: PRE, 5.36°→ F/U, 2.38°, p=0.249). No significant difference was found in the RR and NDI changes in the ACDF group based on balance, but a significant difference was found in RR in the LP group (balance: 61.65%±19.88%, imbalance: 46.90%±15.71%, p=0.046).
Conclusion
We found a significant difference in postoperative alignment in cases of ACDF and LP according to preoperative cervical sagittal balance. The postoperative clinical results of the LP group were more affected by F/U alignment than by the degree of alignment change.

Citations

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  • Progression of Cervical Ossification of Posterior Longitudinal Ligament After Laminoplasty or Laminectomy With Posterior Fixation
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Clinical Articles

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Variation of C-Reactive Protein and White Blood Cell Counts in Spinal Operation: Primary Fusion Surgery Versus Revision Fusion Surgery
Korean J Spine. 2017;14(3):66-70.   Published online September 30, 2017
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Variation of C-Reactive Protein and White Blood Cell Counts in Spinal Operation: Primary Fusion Surgery Versus Revision Fusion Surgery
Korean J Spine. 2017;14(3):66-70.   Published online September 30, 2017
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Objective:
Serum C-reactive protein(CRP) concentrations and white blood cell(WBC) count are commonly used to identify postoperative wound infections. We investigated whether changes in serum CRP levels and WBC counts actually differed between patients undergoing revision spinal fusion surgery and those undergoing a primary fusion. Methods: Patients who underwent posterolateral fusion(PLF) surgery at Pusan National University Yangsan Hospital between October 2013 and April 2015 were considered for this study. Sixty-seven patients with primary lumbar PLF(pPLF) and 21 with revision PLF(rPLF) were enrolled. A retrospective assessment of preoperative and postoperative CRP levels and WBC count was undertaken. Also, we gathered peak CRP day, and CRP normalization days. Comorbidity data were also obtained to evaluate any effects on the course of CRP and WBC count postoperatively. Results: CRP levels peaked at 3 days after surgery. The maximum CRP values recorded for each group: 4.17(standard deviation[SD], 4.18)mg/dL and 4.88(SD, 3.03)mg/dL for pPLF and rPLF. This difference was not statistically significant(p=0.24). A rapid fall in CRP within 5-9 days was observed for both groups. Conclusion: Out of our expectation, changes in CRP levels after spinal fusion surgery follow the same course regardless of whether it is a revision operation or not. Because of this result, both the primary PLF surgery and revision PLF surgery should be monitored using CRP in the similar way and the antibiotic administration should be determined.

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  • Impact of Spinal Instrumentation on Early Postoperative Inflammatory Markers: A Comparative Analysis in the Same Patient Cohort with or without Instrumentation
    Hiroyuki Aono, Shota Takenaka, Yukitaka Nagamoto, Hidekazu Tobimatsu, Tomoya Yamashita, Masayuki Furuya, Hiroyuki Ishiguro, Motoki Iwasaki
    World Neurosurgery.2025; 196: 123681.     CrossRef
  • Systemic immune-inflammatory biomarkers combined with the CRP-albumin-lymphocyte index predict surgical site infection following posterior lumbar spinal fusion: a retrospective study using machine learning
    Zixiang Pang, Jiawei Liang, Jiayi Chen, Yangqin Ou, Qinmian Wu, Shengsheng Huang, Shengbin Huang, Yuanming Chen
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • CHANGES IN MORPHOLOGICAL PARAMETERS OF BLOOD IN RABBITS DURING GASTRIC SURGERY
    D. O. Kovalenko, M. O. Malyuk
    Naukovì Dopovìdì Nacìonalʹnogo Unìversitetu Bìoresursiv ì Prirodokoristuvannâ Ukraïni.2024;[Epub]     CrossRef
  • Inflammatory blood parameters as prognostic factors for implant-associated infection after primary total hip or knee arthroplasty: a systematic review
    Petr Domecky, Anna Rejman Patkova, Katerina Mala-Ladova, Josef Maly
    BMC Musculoskeletal Disorders.2023;[Epub]     CrossRef
  • Post-operative C-reactive protein and white blood cells changes pattern following spinal deformity surgery and its clinical correlation
    Yehia Elbromboly, Mohamed Abdallah Esawy
    Journal of Orthopaedic Surgery and Research.2023;[Epub]     CrossRef
  • Learning Curve and Complications Experience of Oblique Lateral Interbody Fusion : A Single-Center 143 Consecutive Cases
    Bu Kwang Oh, Dong Wuk Son, Su Hun Lee, Jun Seok Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
    Journal of Korean Neurosurgical Society.2021; 64(3): 447.     CrossRef
  • Letter to the Editor Regarding “Perioperative Complications Associated with Severity of Anemia in Geriatric Patients Undergoing Spinal Procedures”
    Aysel Gökçek, Kemal Gökçek, Murat Biteker
    World Neurosurgery.2020; 136: 424.     CrossRef
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    Young Lee, Jeongwook Lim, Seung-Won Choi, Sanghyun Han, Bumsoo Park, Jin-Young Youm
    Korean Journal of Neurotrauma.2019; 15(2): 143.     CrossRef
  • Predictive value of post-operative neutrophil/lymphocyte count ratio for surgical site infection in patients following posterior lumbar spinal surgery
    Chao-Jun Shen, Tao Miao, Zhang-Fu Wang, Zhen-Fa Li, Ling-Qin Huang, Ting-Ting Chen, Wei-Hua Yan
    International Immunopharmacology.2019; 74: 105705.     CrossRef
  • Can Application of Vancomycin Powder into the Operation Field Reduce Surgical Site Infection in Spine Surgery?
    Mikinobu Takeuchi
    Spinal Surgery.2019; 33(3): 241.     CrossRef
  • Limited Predictive Value of Serum Inflammatory Markers for Diagnosing Fracture-Related Infections: results of a large retrospective multicenter cohort study
    Paul Bosch, Janna van den, Joost D.J. Plate, Frank F.A. IJpma, R. Marijn Houwert, Albert Huisman, Falco Hietbrink, Luke P.H. Leenen, Geertje A.M. Govaert
    Journal of Bone and Joint Infection.2018; 3(3): 130.     CrossRef
  • 12,052 View
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Comparison of Radiologic Outcomes of Different Methods in Single-Level Anterior Cervical Discectomy and Fusion
Korean J Spine. 2016;13(3):91-96.   Published online September 30, 2016
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Comparison of Radiologic Outcomes of Different Methods in Single-Level Anterior Cervical Discectomy and Fusion
Korean J Spine. 2016;13(3):91-96.   Published online September 30, 2016
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Objective

Anterior cervical discectomy and fusion (ACDF) is a choice of surgical procedure for cervical degenerative diseases associated with radiculopathy or myelopathy. However, the patients undergoing ACDF still have problems. The purpose of the present study is to evaluate the radiologic results of 3 different methods in single-level ACDF.

Methods

We conducted a retrospective collection of radiological data from January 2011 to December 2014. A total of 67 patients were included in this study. The patients were divided into 3 groups by operation procedure: using stand-alone cage (group cage, n=20); polyether-ether-ketone (PEEK)-titanium combined anchored cage (group AC, n=21); and anterior cervical cage-plate (group CP, n=26). Global cervical lordosis (C2-C7 Cobb angle), fused segment height, fusion rate, and cervical range of motion (ROM) were measured and analyzed at serial preoperative, postoperative, 6-month, and final 1-year follow-up.

Results

Successful bone fusion was achieved in all patients at the final follow-up examination; however, the loss of disc height over 3 mm at the surgical level was observed in 6 patients in group cage. Groups AC and CP yielded significantly better outcomes than group cage in fused segment height and cervical ROM(p=0.01 and p=0.02, respectively). Furthermore, group AC had similar radiologic outcomes to those of group CP.

Conclusion

The PEEK-titanium combined anchored cage may be a good alternative procedure in terms of reducing complications induced by plate after ACDF.

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  • Single-Level Anterior Cervical Discectomy and Interbody Fusion: A Comparison between Porous Tantalum and Polyetheretherketone Cages
    Edoardo Mazzucchi, Giuseppe La Rocca, Andrea Perna, Fabrizio Pignotti, Gianluca Galieri, Vincenzo De Santis, Pierluigi Rinaldi, Francesco Ciro Tamburrelli, Giovanni Sabatino
    Journal of Personalized Medicine.2022; 12(6): 986.     CrossRef
  • Comparison of the effectiveness and safety of bioactive glass ceramic to allograft bone for anterior cervical discectomy and fusion with anterior plate fixation
    Hyung Cheol Kim, Jae Keun Oh, Du Su Kim, Jeffrey S. Roh, Tae Woo Kim, Seong Bae An, Hyeong Seok Jeon, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Do Heum Yoon, Yoon Ha
    Neurosurgical Review.2020; 43(5): 1423.     CrossRef
  • Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
    Chi Hyung Lee, Dong Wuk Son, Su Hun Lee, Jun Seok Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
    Neurospine.2020; 17(1): 156.     CrossRef
  • Cost-Effectiveness Analysis of Cervical Anterior Fusion and Cervical Artificial Disc Replacement in the Korean Medical System
    Hyosang Lee, Ui Chul Kim, Jae Keun Oh, Taehyun Kim, Sohee Park, Yoon Ha
    Journal of Korean Neurosurgical Society.2019; 62(1): 83.     CrossRef
  • Comparison of Adjacent Segment Degeneration, Cervical Alignment, and Clinical Outcomes After One- and Multilevel Anterior Cervical Discectomy and Fusion
    Jun Jae Shin
    Neurospine.2019; 16(3): 589.     CrossRef
  • 10,601 View
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  • 5 Crossref

Case Reports

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Spontaneous Spinal Epidural Hematoma Coexisting Guillan-Barré Syndrome in a Child: A Case Report
Korean J Spine. 2016;13(3):167-169.   Published online September 30, 2016
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Spontaneous Spinal Epidural Hematoma Coexisting Guillan-Barré Syndrome in a Child: A Case Report
Korean J Spine. 2016;13(3):167-169.   Published online September 30, 2016
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Spontaneous spinal epidural hematoma (SSEH) has been reported as a rare cause of spinal cord compression, especially in children. Clinical features are usually nonspecific, although cervicothoracic location of hematoma could be presented with progressive paraplegia. Guillian-Barré syndrome (GBS) is clinically defined as an acute peripheral neuropathy causing progressive limb weakness. Because SSEH and GBS have very similar signs and symptoms, SSEH could be misdiagnosed as GBS. Nevertheless, they can be presented together. We describe a rare case of SSEH coexisting with GBS.

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  • Spontaneous Cervical Epidural Hematoma Presenting with Respiratory Failure
    Hiroaki Ohno, Takashi Fujishiro, Sachio Hayama, Masahiro Mizutani, Hiromitsu Moriuchi, Akifumi Fujita, Masashi Neo
    JBJS Case Connector.2023;[Epub]     CrossRef
  • Recovery without neurological sequelae of traumatic spinal epidural hematoma masquerading as Guillain-Barré syndrome in a child
    Joon Sang Lee, Dong Hyun Kim, Young Se Kwon
    Pediatric Emergency Medicine Journal.2020; 7(1): 49.     CrossRef
  • Spontaneous spinal epidural hematoma mimicking Guillain-Barre Syndrome
    Aya Kondo, Hiroshi Yamaguchi, Yusuke Ishida, Daisaku Toyoshima, Mai Azumi, Nobuyuki Akutsu, Junji Koyama, Hiroshi Kurosawa, Atushi Kawamura, Azusa Maruyama
    Brain and Development.2019; 41(4): 392.     CrossRef
  • Posttraumatic Guillain-Barré Syndrome Immediately Following a Traffic Accident
    Jungook Kim, Ho Yong Choi, Young Min Lee, Joon Soo Kim
    Korean Journal of Spine.2017; 14(3): 121.     CrossRef
  • 10,115 View
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  • 4 Crossref

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Migration of an Intracranial Subdural Hematoma to the Spinal Subdural Space: A Case Report
Korean J Spine. 2015;12(3):207-209.   Published online September 30, 2015
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Migration of an Intracranial Subdural Hematoma to the Spinal Subdural Space: A Case Report
Korean J Spine. 2015;12(3):207-209.   Published online September 30, 2015
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A 57-year-old man complained of severe lower back pain and radicular pain in both legs for 1 week after falling from a ladder. Magnetic resonance imaging (MRI) of the spine showed a subdural hematoma (SDH), which was surgically removed. The patient had no back pain or the radicular leg pain at 2 weeks post-surgery. However, he complained of diffuse headaches upon follow-up. Brain computed tomography (CT) and MRI revealed an intracranial SDH, which was immediately removed by surgery. During his 1-year follow-up, he reported that the pain had resolved without recurrence. Simultaneous spinal and intracranial SDH are rare and no standard treatment exists for this condition. This case suggests that it is possible that an intracranial SDH can migrate into the cerebrospinal fluid (CSF) space through an arachnoid tear. CSF circulation allows the intracranial SDH to enter subarachnoid spaces encasing the spinal cord. In order to prevent irreversible damage, surgical intervention should be considered for case of spinal SDH with progressive neurological deficits.

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  • Rapid spontaneous migration and resolution of an acute subdural hematoma: A case report and comprehensive literature review
    Imad-eddine Sahri, Abdellaoui Mohammed, Elkorno Mohammed, Khalil Chafi, Achraf Moussa, Laaguili Jawad, El Asri Abad Cherif, Gazzaz Miloudi
    Radiology Case Reports.2026; 21(6): 2394.     CrossRef
  • Traumatic Isolated Lumbosacral Spinal Subdural Hematoma in a Pediatric Patient: A Case Report and Literature Review
    Alexander Torres-Rey, Esteban R Rivera, Luis E Garcia-Irizarry, Samuel Estronza, Emil A Pastrana
    Cureus.2025;[Epub]     CrossRef
  • Concurrent spontaneous spinal and tentorial subdural hematomas in an older patient receiving anticoagulation treatment: a case report
    Joo Hyung Shin, Hyung Cheol Kim
    Journal of Korean Society of Geriatric Neurosurgery.2025; 21(2): 90.     CrossRef
  • Concurrent intracranial and spinal subdural hematomas: postoperative intracranial progression following surgical evacuation of spinal subdural hematoma: A case report and literature review
    Zehua Gong, Zhaohui Zhao
    Medicine.2025; 104(44): e45564.     CrossRef
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    Catherine Wassef, Anmol Almast, Shehanaz Ellika
    BMJ Case Reports.2022; 15(12): e251984.     CrossRef
  • Lumbosacral subdural hematoma associated with cranial subdural hematoma and craniocerebral surgery: Three cases and a systemic literature review
    H. Yokota, D. Wajima, Y. Ida
    Neurochirurgie.2021; 67(5): 470.     CrossRef
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    Zachary R. Porter, Mark D. Johnson, Paul S. Horn, Laura B. Ngwenya
    Interdisciplinary Neurosurgery.2020; 19: 100570.     CrossRef
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    Jason K. Hsieh, Samantha Colby, Daniel Nichols, Efstathios Kondylis, James K.C. Liu
    World Neurosurgery.2020; 141: 44.     CrossRef
  • Traumatic Subacute Spinal Subdural Hematoma Concomitant with Symptomatic Cranial Subdural Hematoma: Possible Mechanism
    Nyoman Golden, Made Widhi Asih
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Clinical Article

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Effectiveness of the Laminoplasty in the Elderly Patients with Cervical Spondylotic Myelopathy
Korean J Spine. 2014;11(2):39-44.   Published online June 30, 2014
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Effectiveness of the Laminoplasty in the Elderly Patients with Cervical Spondylotic Myelopathy
Korean J Spine. 2014;11(2):39-44.   Published online June 30, 2014
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Objective

The purpose of this study is to evaluate clinical and radiological outcomes analysis of the laminoplasty in the elderly patients, and to compare with the non-elderly patients.

Methods

A retrospective study of the short term result in patients who had treated with the laminoplasty for cervical spondylotic myelopathy (CSM) was performed. From January 2008 to December 2012, total 62 patients were operated with single open-door technique because of CSM; 28 patients were the elderly and 34 patients were the non-elderly. We evaluated some factors including sex, symptom duration, estimated blood loss during operation, operation time, hospitalization day, complications, pre- and postoperative modified Japanese Orthopedic Association (mJOA) score, recovery rate of mJOA score, achieved mJOA score, mean cervical canal width and expansion ratio of antero-posterior diameter in order to identify difference between the two group. Clinical outcomes were calculated with the recovery rate of mJOA score at the time of one year after operation.

Results

Mean age were 71.9 in the elderly group and 52.9 in the non-elderly group. Although postoperative mJOA score in the elderly group was lower than that of the non-elderly group, achieved mJOA score was statistically same between the two groups. Other clinical and radiological outcomes were also statistically same.

Conclusion

We conclude that the laminoplasty also assures good clinical outcomes in the elderly patients with CSM, same as in the non-elderly group.

Citations

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  • Predicting Neck Dysfunction After Open-Door Cervical Laminoplasty — A Prospective Cohort Patient-Reported Outcome Measurement Study
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    Neurospine.2024; 21(4): 1053.     CrossRef
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Case Report

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Ventrally Located Cervical Dumbbell Ganglioneuroma Producing Spinal Cord Compression
Korean J Spine. 2013;10(4):246-248.   Published online December 31, 2013
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Ventrally Located Cervical Dumbbell Ganglioneuroma Producing Spinal Cord Compression
Korean J Spine. 2013;10(4):246-248.   Published online December 31, 2013
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Ganglioneuroma is an uncommon benign tumor and arise from neural crest cells or sympathetic and peripheral nerves. A 13-year-old boy was referred to our institute and presented with three-day history of right upper extremity weakness associated with neck pain for nearly one month. Magnetic resonance imaging showed right side dumbbell shaped extramedullary lesion at the C2-3 level extending outside through neural foramen. Paraspinal and posterior neck mass, cafe au lait spot was identified. We performed surgical decompression of the spinal cord by resection of intradural portion mass. Histopathological diagnosis was ganglioneuroma.

Citations

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