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Efficacy of Transforaminal Endoscopic Lumbar Discectomy in Elderly Patients Over 65 Years of Age Compared to Young Adults
Neurospine. 2023;20(2):597-607.   Published online June 30, 2023
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Efficacy of Transforaminal Endoscopic Lumbar Discectomy in Elderly Patients Over 65 Years of Age Compared to Young Adults
Neurospine. 2023;20(2):597-607.   Published online June 30, 2023
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Objective
Spine surgery rates are increasing in the elderly population due to social aging, and it is known that prognoses related to surgery are worse for the elderly compared to younger individuals. However, minimally invasive surgery, such as full endoscopic surgery, is considered safe with low complication rates due to minimal damage to surrounding tissues. In this study, we compared outcomes of transforaminal endoscopic lumbar discectomy (TELD) in elderly and younger patients with disc herniation in the lumbosacral region.
Methods
We retrospectively analyzed the data of 249 patients who underwent TELD at a single center between January 2016 to December 2019, with a minimum follow-up of 3 years. Patients were allocated to 2 groups: a young group aged ≤ 65 years (n = 202) or an elderly group aged > 65 years (n = 47). We evaluated baseline characteristics, clinical outcomes, surgery-related outcomes, radiological outcomes, perioperative complications, and adverse events during the 3-year follow-up period.
Results
Baseline characteristics, including age, general condition based on American Society of Anesthesiologist physical status classification grade, age-Charlson Comorbidity Index, and disc degeneration, were worse in elderly group (p < 0.001). However, except for leg pain at 4 weeks after surgery, overall outcomes, including pain improvement, radiological change, operation time, blood loss, and hospital stay, were not different between the 2 groups. Furthermore, the rates of perioperative complications (9 patients [4.46%] in the young group and 3 patients [6.38%] in the elderly group, p = 0.578) and adverse events over the 3-year follow-up period (32 patients [15.84%] in the young group and 9 patients [19.15%] in the elderly group, p = 0.582) were comparable in the 2 groups.
Conclusion
Our findings suggest that TELD produces similar outcomes in both elderly and younger patients with a herniated disc in the lumbosacral region. TELD can be considered a safe option for appropriately selected elderly patients.

Citations

Citations to this article as recorded by  Crossref logo
  • Propensity score-matched analysis of percutaneous endoscopic versus conservative treatment for lumbar disc herniation in high-risk octogenarians
    Beiping OuYang, Hongyan Sun, Kaiwei Zhang, Chunshan Luo, Li Zhang
    Scientific Reports.2026;[Epub]     CrossRef
  • Clinical Outcomes of Open, Tubular, and Endoscopic Lumbar Discectomy
    Dillon H. Stone, Garrison P. Bentz, John O’Malley, Lane McCoy, Anshum Sood, Salim Yakdan, Camilo A. Molina, Jacob Buchowski, John C. Clohisy, Jacob K. Greenberg, Brian J. Neuman, Keith Bridwell, Blake K. Montgomery, Karan Joseph, Benjamin Plog, Lucas Budd
    Spine Open.2026;[Epub]     CrossRef
  • Safety and Utility of Bilateral-contralateral Decompression for Adjacent Segment Stenosis After Lumbar Interbody Fusion Using Unilateral Biportal Endoscopy
    Dong Hyun Lee, Choon Keun Park, Jae-Won Jang, Dong-Geun Lee
    Clinical Spine Surgery.2025; 38(10): E488.     CrossRef
  • Evaluating the learning curve and operative time of interlaminar and transforaminal endoscopic lumbar discectomy
    Youssef Jamaleddine, Ahmad Haj Hussein, Mohamad Omar Honeine, Elio Daccache, Sarah El Hajjar, Ramzi Moucharafieh, Nizar Natout, Mohammad Badra
    Brain and Spine.2025; 5: 104225.     CrossRef
  • Integrated Optical and Magnetic Navigation for Simplified Percutaneous Transforaminal Endoscopic Lumbar Discectomy: A Novel Approach
    Xing-Chen Yao, Jun-Peng Liu, Xin-Ru Du, Li Guan, Yong Hai, Jincai Yang, Aixing Pan
    Neurospine.2025; 22(1): 297.     CrossRef
  • O-arm navigation-based transforaminal unilateral biportal endoscopic discectomy for upper lumbar disc herniation: an innovative preliminary study
    Dong Hyun Lee, Choon Keun Park, Jin-Sung Kim, Jin Sub Hwang, Jin Young Lee, Dong-Geun Lee, Jae-Won Jang, Jun Yong Kim, Yong-Eun Cho, Dong Chan Lee
    Asian Spine Journal.2025; 19(2): 194.     CrossRef
  • A Systematic Review and Meta-Analysis of Preoperative Characteristics and Postoperative Outcomes in Patients Undergoing Endoscopic Spine Surgery: Part I Endoscopic Microdiscectomy
    Long Di, Andrew Wang, Kate E. Stillman, Lauren K. Tierney, Solomon G. Jackson, Andrew J. Sasser, Alexander Valecillo, Tyler Cardinal, Seth Tigchelaar, Adham M. Khalafallah, Gregory Basil
    Journal of Clinical Medicine.2025; 14(19): 6757.     CrossRef
  • Impact of age and frailty on postoperative outcomes of single-level lumbar unilateral laminectomy bilateral decompression via biportal endoscopic spine surgery: retrospective, single institute study, Korea
    Hae Yoon Jung, Jung Hwan Lee, Seung Yoon Song, Sung Hoon Cho, Young Joo Kim, Seung Chan Yoo, Chung Kee Chough
    Journal of Korean Society of Geriatric Neurosurgery.2025; 21(2): 49.     CrossRef
  • A Retrospective Comparative Analysis of Transforaminal Epidural Steroid Injections and Percutaneous Transforaminal Endoscopic Discectomy for Managing Lumbar Radiculopathy in Super Elderly Patients
    Jian Zhou, An'nan Hu, Xiaogang Zhou, Jian Dong
    Clinical Interventions in Aging.2025; Volume 20: 2749.     CrossRef
  • Screening patients requiring secondary lumbar surgery for degenerative lumbar spine diseases: a nationwide sample cohort study
    Hangeul Park, Juhee Lee, Yunhee Choi, Jun-Hoe Kim, Sum Kim, Young-Rak Kim, Chang-Hyun Lee, Sung Bae Park, Kyoung-Tae Kim, John M. Rhee, Chi Heon Kim
    Scientific Reports.2024;[Epub]     CrossRef
  • A new technique for low back pain in lumbar disc herniation: percutaneous endoscopic lumbar discectomy combined with sinuvertebral nerve ablation
    Yanjun Huang, Shangshu Wei, Yanzhu Shen, Sizheng Zhan, Ping Yi, Xiangsheng Tang
    Journal of Orthopaedic Surgery and Research.2024;[Epub]     CrossRef
  • Full-Endoscopic Spinal Surgery for Older Patients With Degenerative Spinal Pathology: A Narrative Review
    Jongpil Eun, Youngmin Oh
    Journal of Minimally Invasive Spine Surgery and Technique.2024; 9(Suppl 2): S160.     CrossRef
  • Efficacy of percutaneous endoscopic lumbar discectomy (PELD) combined with sinuvertebral nerve ablation versus PELD for low back pain in lumbar disc herniation
    Yanjun Huang, Shangshu Wei, Shuyue Yang, Yanzhu Shen, Haoning Ma, Ping Yi, Xiangsheng Tang
    Journal of Orthopaedic Surgery and Research.2024;[Epub]     CrossRef
  • 8,531 View
  • 195 Download
  • 13 Web of Science
  • 13 Crossref

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Factors Predicting the Clinical Outcome After Trans-sacral Epiduroscopic Laser Decompression for Lumbar Disc Herniation
Neurospine. 2021;18(2):336-343.   Published online June 30, 2021
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Factors Predicting the Clinical Outcome After Trans-sacral Epiduroscopic Laser Decompression for Lumbar Disc Herniation
Neurospine. 2021;18(2):336-343.   Published online June 30, 2021
Close
Objective
Previous literatures have demonstrated widely variable clinical results after transsacral epiduroscopic laser decompression (SELD) and the factors predicting outcomes are not yet established. Therefore, we analyzed the clinical outcome and associated predictive factors of SELD in patients with lumbar disc herniation.
Methods
Between 2015 and 2018, 82 patients who underwent single-level SELD and followed up at least 6 months were enrolled. The overall success rate (excellent or good results at final follow-up) was 58.5% according to Odom’s criteria. Based on this result, patients were divided to 2 groups: a favorable group (n = 48) and an unfavorable group (n = 34). A retrospective review of the baseline characteristics and clinical outcome were conducted to reveal the predictive factors.
Results
As expected, improvement of pain and patient satisfaction, was more favorable in the favorable group (p < 0.05). Moreover, the rate of additional procedure was lower in the favorable group (4.2%, 2 of 48 patients) than in the unfavorable group (35.3%, 12 of 34 patients) (p = 0.011). Among the various baseline characteristics, the only significant predictive factor for favorable outcome was the presence of a high-intensity zone (HIZ) on preoperative magnetic resonance imaging (50.0% [24 of 48 patients] in the favorable group vs. 11.8% [4 of 34 patients] in the unfavorable group; odds ratio, 15.67; p = 0.024).
Conclusion
Although SELD for lumbar disc herniation resulted in a less favorable clinical outcome than that reported in previous studies, in patients with a HIZ, SELD can be an effective minimally invasive surgery to relieve low back pain and/or leg pain.

Citations

Citations to this article as recorded by  Crossref logo
  • Shape-memory collagen scaffold combined with hyaluronic acid for repairing intervertebral disc
    Young Won Koo, Chang Su Lim, Anjani Darai, JiUn Lee, Wonjin Kim, Inbo Han, Geun Hyung Kim
    Biomaterials Research.2023;[Epub]     CrossRef
  • Narrative Review of Pathophysiology and Endoscopic Management of Basivertebral and Sinuvertebral Neuropathy for Chronic Back Pain
    Hyeun Sung Kim, Pang Hung Wu, Il-Tae Jang
    Journal of Korean Neurosurgical Society.2023; 66(4): 344.     CrossRef
  • Cost-utility analysis of endoscopic lumbar discectomy following a uniform clinical pathway in the Korean national health insurance system
    Chi Heon Kim, Yunhee Choi, Chun Kee Chung, Seung Heon Yang, Chang-Hyun Lee, Sung Bae Park, Keewon Kim, Sun Gun Chung, Sathish Muthu
    PLOS ONE.2023; 18(6): e0287092.     CrossRef
  • Enhanced Intervertebral Disc Repair via Genetically Engineered Mesenchymal Stem Cells with Tetracycline Regulatory System
    Yeji Kim, Seong Bae An, Sang-Hyuk Lee, Jong Joo Lee, Sung Bum Kim, Jae-Cheul Ahn, Dong-Youn Hwang, Inbo Han
    International Journal of Molecular Sciences.2023; 24(22): 16024.     CrossRef
  • Safety and Feasibility of Intradiscal Administration of Matrilin-3-Primed Adipose-Derived Mesenchymal Stromal Cell Spheroids for Chronic Discogenic Low Back Pain: Phase 1 Clinical Trial
    Dong Hyun Lee, Kwang-Sook Park, Hae Eun Shin, Sung Bum Kim, Hyejeong Choi, Seong Bae An, Hyemin Choi, Joo Pyung Kim, Inbo Han
    International Journal of Molecular Sciences.2023; 24(23): 16827.     CrossRef
  • Logistic Model and Gradient Boosting Machine Model for Physical Therapy of Lumbar Disc Herniation
    Ping Zhao, Jin Xue, Xiaomei Xu, Lifei Wang, Dan Chen, Kelvin Wong
    Computational and Mathematical Methods in Medicine.2022; 2022: 1.     CrossRef
  • 7,897 View
  • 176 Download
  • 6 Web of Science
  • 6 Crossref

Clinical Articles

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Variation of C-Reactive Protein and White Blood Cell Counts in Spinal Operation: Primary Fusion Surgery Versus Revision Fusion Surgery
Korean J Spine. 2017;14(3):66-70.   Published online September 30, 2017
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Variation of C-Reactive Protein and White Blood Cell Counts in Spinal Operation: Primary Fusion Surgery Versus Revision Fusion Surgery
Korean J Spine. 2017;14(3):66-70.   Published online September 30, 2017
Close
Objective:
Serum C-reactive protein(CRP) concentrations and white blood cell(WBC) count are commonly used to identify postoperative wound infections. We investigated whether changes in serum CRP levels and WBC counts actually differed between patients undergoing revision spinal fusion surgery and those undergoing a primary fusion. Methods: Patients who underwent posterolateral fusion(PLF) surgery at Pusan National University Yangsan Hospital between October 2013 and April 2015 were considered for this study. Sixty-seven patients with primary lumbar PLF(pPLF) and 21 with revision PLF(rPLF) were enrolled. A retrospective assessment of preoperative and postoperative CRP levels and WBC count was undertaken. Also, we gathered peak CRP day, and CRP normalization days. Comorbidity data were also obtained to evaluate any effects on the course of CRP and WBC count postoperatively. Results: CRP levels peaked at 3 days after surgery. The maximum CRP values recorded for each group: 4.17(standard deviation[SD], 4.18)mg/dL and 4.88(SD, 3.03)mg/dL for pPLF and rPLF. This difference was not statistically significant(p=0.24). A rapid fall in CRP within 5-9 days was observed for both groups. Conclusion: Out of our expectation, changes in CRP levels after spinal fusion surgery follow the same course regardless of whether it is a revision operation or not. Because of this result, both the primary PLF surgery and revision PLF surgery should be monitored using CRP in the similar way and the antibiotic administration should be determined.

Citations

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  • Comparable Fusion Response, but Increased Inflammatory Response, with Escherichia coli-Derived Recombinant Human Bone Morphogenetic Protein-2 in Posterior Lumbar Interbody Fusion Surgery
    Mu Ha Lee, Hyun Jun Jang, Kyung Hyun Kim, Jeong-Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Jae Keun Oh, Bong Ju Moon
    Journal of Clinical Medicine.2026; 15(11): 4026.     CrossRef
  • Impact of Spinal Instrumentation on Early Postoperative Inflammatory Markers: A Comparative Analysis in the Same Patient Cohort with or without Instrumentation
    Hiroyuki Aono, Shota Takenaka, Yukitaka Nagamoto, Hidekazu Tobimatsu, Tomoya Yamashita, Masayuki Furuya, Hiroyuki Ishiguro, Motoki Iwasaki
    World Neurosurgery.2025; 196: 123681.     CrossRef
  • Systemic immune-inflammatory biomarkers combined with the CRP-albumin-lymphocyte index predict surgical site infection following posterior lumbar spinal fusion: a retrospective study using machine learning
    Zixiang Pang, Jiawei Liang, Jiayi Chen, Yangqin Ou, Qinmian Wu, Shengsheng Huang, Shengbin Huang, Yuanming Chen
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • CHANGES IN MORPHOLOGICAL PARAMETERS OF BLOOD IN RABBITS DURING GASTRIC SURGERY
    D. O. Kovalenko, M. O. Malyuk
    Naukovì Dopovìdì Nacìonalʹnogo Unìversitetu Bìoresursiv ì Prirodokoristuvannâ Ukraïni.2024;[Epub]     CrossRef
  • Inflammatory blood parameters as prognostic factors for implant-associated infection after primary total hip or knee arthroplasty: a systematic review
    Petr Domecky, Anna Rejman Patkova, Katerina Mala-Ladova, Josef Maly
    BMC Musculoskeletal Disorders.2023;[Epub]     CrossRef
  • Post-operative C-reactive protein and white blood cells changes pattern following spinal deformity surgery and its clinical correlation
    Yehia Elbromboly, Mohamed Abdallah Esawy
    Journal of Orthopaedic Surgery and Research.2023;[Epub]     CrossRef
  • Learning Curve and Complications Experience of Oblique Lateral Interbody Fusion : A Single-Center 143 Consecutive Cases
    Bu Kwang Oh, Dong Wuk Son, Su Hun Lee, Jun Seok Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
    Journal of Korean Neurosurgical Society.2021; 64(3): 447.     CrossRef
  • Letter to the Editor Regarding “Perioperative Complications Associated with Severity of Anemia in Geriatric Patients Undergoing Spinal Procedures”
    Aysel Gökçek, Kemal Gökçek, Murat Biteker
    World Neurosurgery.2020; 136: 424.     CrossRef
  • Changes of Biomarkers before and after Antibiotic Treatment in Spinal Infection
    Young Lee, Jeongwook Lim, Seung-Won Choi, Sanghyun Han, Bumsoo Park, Jin-Young Youm
    Korean Journal of Neurotrauma.2019; 15(2): 143.     CrossRef
  • Predictive value of post-operative neutrophil/lymphocyte count ratio for surgical site infection in patients following posterior lumbar spinal surgery
    Chao-Jun Shen, Tao Miao, Zhang-Fu Wang, Zhen-Fa Li, Ling-Qin Huang, Ting-Ting Chen, Wei-Hua Yan
    International Immunopharmacology.2019; 74: 105705.     CrossRef
  • Can Application of Vancomycin Powder into the Operation Field Reduce Surgical Site Infection in Spine Surgery?
    Mikinobu Takeuchi
    Spinal Surgery.2019; 33(3): 241.     CrossRef
  • Limited Predictive Value of Serum Inflammatory Markers for Diagnosing Fracture-Related Infections: results of a large retrospective multicenter cohort study
    Paul Bosch, Janna van den, Joost D.J. Plate, Frank F.A. IJpma, R. Marijn Houwert, Albert Huisman, Falco Hietbrink, Luke P.H. Leenen, Geertje A.M. Govaert
    Journal of Bone and Joint Infection.2018; 3(3): 130.     CrossRef
  • 12,310 View
  • 149 Download
  • 12 Crossref

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Is Surgical Drain Useful for Lumbar Disc Surgery?
Korean J Spine. 2016;13(1):20-23.   Published online March 31, 2016
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Is Surgical Drain Useful for Lumbar Disc Surgery?
Korean J Spine. 2016;13(1):20-23.   Published online March 31, 2016
Close
Objective

Surgical drains are commonly used after the spine surgeries for minimizing hematoma formation, which can delay wound healing and may become a source of fibrosis, infection, and pain. The drain, however, may provide a direct route for infection if it is contaminated. Our objective was to survey the relationship between surgical drains and infection.

Methods

The 70 patients who had undergone single-level lumbar discectomy from April 2011 to March 2012 were retrospectively analyzed. Each patient's medical chart and magnetic resonance image were thoroughly reviewed after all the patients had been divided into the drainage and the nondrainage groups. The amounts and durations of the surgical drains in the drainage group were analyzed. Additionally, the levels of C-reactive protein, rates of infection, scores of preoperative and postoperative visual analog scale (VAS), and lengths of hospital stay after operation were compared between the 2 groups.

Results

In this study, 70 patients were retrospectively analyzed; out of which, 42 and 28 patients were included in the drainage and the nondrainage groups, respectively. Two of the postoperative infection cases in the nondrainage group required to undergo repeated operations. The frequency of the postoperative infection cases was higher in the nondrainage group than in the drainage group; however, there was no significant statistical difference between the 2 groups (p=0.157).

Conclusion

Surgical drains did not elevate postoperative infection. Furthermore, drain tip cultures allowed us to detect postoperative infection at an early stage, and it led to faster initiation of antibiotics treatment.

Citations

Citations to this article as recorded by  Crossref logo
  • Wound Healing Problems After Spinal Surgery: A Study on Possible Causes and Solutions
    Lijing Ran, Xiao Liang
    International Wound Journal.2026;[Epub]     CrossRef
  • Delayed postoperative spinal epidural hematoma after one-hole split endoscope discectomy: a case report and literature review
    Haonan Li, Youzhi Zhou, Yubo Zhou, Tao Liu, Peng Gao, Miao Ge, Xu Zhong, Koji Uotani, Masato Tanaka, Ying Tan, Mishan Wu
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Prevention and Management of Posterior Wound Complications Following Oncologic Spine Surgery: Narrative Review of Available Evidence and Proposed Clinical Decision-Making Algorithm
    Owen P. Leary, Aayush Setty, Jung Ho Gong, Rohaid Ali, Jared S. Fridley, Charles G. Fisher, Arjun Sahgal, Laurence D. Rhines, Jeremy J. Reynolds, Áron Lazáry, Ilya Laufer, Alessandro Gasbarrini, Nicolas Dea, Jorrit-Jan Verlaan, Chetan Bettegowda, Stefano
    Global Spine Journal.2025;[Epub]     CrossRef
  • Cauda Equina Syndrome Without Perineal Sensory Changes or Lower Extremity Neurological Deficits Following Postoperative Spinal Epidural Hematoma: A Case Report and Literature Review
    Guanyi Liu, Qing Li, Hongfeng Ruan, Bingke Zhu, Weihu Ma, Yong Hu
    Orthopaedic Surgery.2025; 17(2): 653.     CrossRef
  • RETRACTED: Effect of drain placement in short‐level spinal surgery on postoperative wound infection: A meta‐analysis
    Baoming Zhan, Shiqiang Fang, Xiuhong Lv, Xuesheng Xie, Xing Wang
    International Wound Journal.2024;[Epub]     CrossRef
  • Effectiveness of Surgical Drains in Obese Patients Undergoing Lumbar Discectomy
    Aryadev Jayakrishnan, Hariprasad Seenappa, Manoj K Ramachandraiah
    Cureus.2024;[Epub]     CrossRef
  • Role of Spinal Surgery Drainage Techniques in Postoperative Outcomes: Insights From a Comprehensive Literature Review
    Wamedh E Matti, Hussain J Kadhim, Ahmed M Taha, Maher K Mustafa, Rasha A Alshakarchy, Rania H Al-Taie, Mustafa Ismail
    Cureus.2024;[Epub]     CrossRef
  • Natural language processing for the automated detection of intra-operative elements in lumbar spine surgery
    Sayan Biswas, Lareyna McMenemy, Ved Sarkar, Joshua MacArthur, Ella Snowdon, Callum Tetlow, K. Joshi George
    Frontiers in Surgery.2023;[Epub]     CrossRef
  • Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary
    Terence Tan, Hui Lee, Milly S. Huang, Joost Rutges, Travis E. Marion, Joseph Mathew, Mark Fitzgerald, Augusto Gonzalvo, Martin K. Hunn, Brian K. Kwon, Marcel F. Dvorak, Jin Tee
    The Spine Journal.2020; 20(3): 435.     CrossRef
  • Risk–benefit analysis of wound drain usage in spine surgery: a systematic review and meta-analysis with evidence summary
    Sathish Muthu, Eswar Ramakrishnan, Karthick Kumar Natarajan, Girinivasan Chellamuthu
    European Spine Journal.2020; 29(9): 2111.     CrossRef
  • Analysis of efficacy in postoperative use of closed suction drain in cases of traumatic dorsolumbar spine injury
    Vineet Kumar, Ajai Singh, Shah Waliullah, Deepak Kumar
    Journal of Orthopedics, Traumatology and Rehabilitation.2019; 11(1): 1.     CrossRef
  • Methicillin-Resistant Staphylococcus aureus Nasal Swab and Suction Drain Tip Cultures in 4573 Spinal Surgeries
    Atsuyuki Kawabata, Kenichiro Sakai, Hirokazu Sato, Shinichi Sasaki, Ichiro Torigoe, Masaki Tomori, Masato Yuasa, Yu Matsukura, Yoshiyasu Arai
    Spine.2018; 43(7): E430.     CrossRef
  • Prophylaxis of surgical site infection in adult spine surgery: A systematic review
    Reina Yao, Terence Tan, Jin Wee Tee, John Street
    Journal of Clinical Neuroscience.2018; 52: 5.     CrossRef
  • A systematic review and meta-analysis of wound drains in non-instrumented lumbar decompression surgery
    Christopher L. Davidoff, Jeffrey M. Rogers, Mary Simons, Andrew S. Davidson
    Journal of Clinical Neuroscience.2018; 53: 55.     CrossRef
  • 9,486 View
  • 116 Download
  • 14 Crossref

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The Actual Level of Symptomatic Soft Disc Herniation in Patients with Cervical Disc Herniation
Korean J Spine. 2015;12(3):130-134.   Published online September 30, 2015
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The Actual Level of Symptomatic Soft Disc Herniation in Patients with Cervical Disc Herniation
Korean J Spine. 2015;12(3):130-134.   Published online September 30, 2015
Close
Objective

The aim of this study was to predict the relationship between the symptomatic disc herniation level and the osteophyte level or decreased disc height in patients with cervical disc herniation.

Methods

Between January 2011 and December 2012, 69 patients with an osteophyte of the cervical spine underwent surgery at a single center due to soft cervical disc herniation. Data including soft disc herniation level, osteophyte level in the posterior vertebral margin, Cobb's angle, and symptom duration were retrospectively assessed. The patients were divided into three groups according to the relationship between the degenerative change level and the level of reported symptoms.

Results

Among the 69 patients, 48 (69.6%) showed a match between osteophyte level and soft disc herniation level. Disc herniation occurred at the adjacent segment to degenerative osteophyte level in 12 patients (17.4%) and at both the adjacent and the osteophyte level in nine (13.0%). There was no significant difference in Cobb's angle or duration among the three groups. Osteophyte type was not significant. The mean disc height of the prominent degenerative change level group was lower than the adjacent segment level, but this was not significant.

Conclusion

Soft cervical disc herniation usually occurs at the level an osteophyte forms. However, it may also occur at segments adjacent to that of the osteophyte level. Therefore, in patients with cervical disc herniation, although a prominent osteophyte alone may appear on plain radiography, we must suspect the presence of soft disc herniation at other levels.

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  • Correlation between T2* (T2 star) relaxation time and cervical intervertebral disc degeneration
    Minghua Huang, Yong Guo, Qiong Ye, Lei Chen, Kai Zhou, Qingjun Wang, Lixin Shao, Qinglei Shi, Chun Chen
    Medicine.2016; 95(47): e4502.     CrossRef
  • 12,710 View
  • 91 Download
  • 1 Crossref

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Influence of Compression Ratio Differences between Magnetic Resonance Images and Simple Radiographs on Osteoporotic Vertebral Compression Fracture Prognosis after Vertebroplasty
Korean J Spine. 2014;11(2):62-67.   Published online June 30, 2014
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Influence of Compression Ratio Differences between Magnetic Resonance Images and Simple Radiographs on Osteoporotic Vertebral Compression Fracture Prognosis after Vertebroplasty
Korean J Spine. 2014;11(2):62-67.   Published online June 30, 2014
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Objective

The extent of collapse progression after vertebroplasty in osteoporotic vertebral compression fractures (OVCF) has known to be various. In this study, we investigated that how much difference of compression ratio between standing simple radiograph and supine magnetic resonance imaging (MRI) affects the collapse progression after vertebroplasty.

Methods

This retrospective cohort study was carried out based on 27 patients with 31 OVCFs undergone vertebrplastyin the thoracolumbar junction (T12-L2), from January to December 2009. The OVCFs were divided to two groups, the smaller group A and larger group B, by mean compression ratio difference (8.1%) between standing simple radiograph and supine MRI.

Results

There were no significant differences in the baseline characteristics of the two groups except age. There were also no significant differences between the periodic compression ratio, back pain, Cobb's angle during follow-up period. However, Group B seemed to show improvements from the initial state to the point just after the operation, but eventually took a much worse course than group A. In the end, judging from the compression ratios of the two groups at the last follow up, group A showed less progression.

Conclusion

Although the clinical outcome was not different significantly, a greater compression ratio difference in the initial study resulted in a greater collapse progression at last follow-up. Therefore, we suggest that it is important to check the initial standing simple radiograph, as well as supine MRI, for predicting collapse progression after vertebroplasty.

Citations

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  • Pedicle Enhancement on Contrast-Enhanced MRI as a Risk Factor for Progressive Collapse in Acute Osteoporotic Compression Fractures
    Byung-Jou Lee, Seonghoon Jeong, Kwang Hyeon Kim, Hae-Won Koo
    Spine.2026; 51(12): 877.     CrossRef
  • Research on Vertebral Segmentation and Bone Mineral Density Calculation Method Based on DCNN
    晓晖 毛
    Software Engineering and Applications.2025; 14(05): 974.     CrossRef
  • Morphometric measurements can improve prediction of progressive vertebral deformity following vertebral damage
    Jin Luo, Patricia Dolan, Michael A. Adams, Deborah J. Annesley-Williams
    European Spine Journal.2022; 31(1): 70.     CrossRef
  • A deep learning algorithm for automated measurement of vertebral body compression from X-ray images
    Jae Won Seo, Sang Heon Lim, Jin Gyo Jeong, Young Jae Kim, Kwang Gi Kim, Ji Young Jeon
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Prophylactic Intrawound Application of Vancomycin Powder in Instrumented Spinal Fusion Surgery
Korean J Spine. 2013;10(3):121-125.   Published online September 30, 2013
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Prophylactic Intrawound Application of Vancomycin Powder in Instrumented Spinal Fusion Surgery
Korean J Spine. 2013;10(3):121-125.   Published online September 30, 2013
Close
Objective

We evaluated the effect of intrawound application of vancomycin powder for infection prophylaxis in wounds caused by instrumented spinal surgery.

Methods

From July 2012 to December 2012, 74 instrumented spinal fusion procedures were performed by 1 neurosurgeon at a single institute. We divided the patients into 2 groups, depending on the use of local application of vancomycin powder: Group A (intrawound application of vancomycin powder with perioperative intravenous cefazolin) and Group B (perioperative intravenous cefazolin alone). A retrospective cohort comparative study was conducted between the 2 groups. The age, sex, comorbidities, smoking, surgical procedure, and surgical site infection (SSI) of consecutive patients were analyzed.

Results

Among the 74 patients, 34 patients were assigned to group A and 40 patients to group B. No wound infections were found in group A. However, in group B, 5 cases of SSI (12.5%) were found. A statistically significant reduction in SSI incidence was observed in group A (p<0.033). The 5 cases of SSI in group B consisted of 3 cases of deep wound infection and 2 cases of superficial wound infection. All SSIs were found in cases of posterior approach surgery and tended to be more frequent in older patients.

Conclusion

Adjunctive intrawound local application of vancomycin powder is a simple uncomplicated procedure and can result in a significant reduction of SSI in instrumented spinal fusions. Furthermore, culture of the drainage tip is very important for confirmation of deep wound infection.

Citations

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Case Report

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Hibernoma in the Thoracic Back Muscle Accompanied by Neurilemmoma
Korean J Spine. 2012;9(4):362-364.   Published online December 31, 2012
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Hibernoma in the Thoracic Back Muscle Accompanied by Neurilemmoma
Korean J Spine. 2012;9(4):362-364.   Published online December 31, 2012
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Hibernoma is a very rare, benign soft fatty tumor that derived from remnants of fetal brown tissue. The following case of hibernoma break out occurred from a patient who had received surgical resection of neurilemmoma. There has never been a case that reported about hibernoma accompanied by neurilemmoma. It is anticipated that this experience would be helpful to other physicians who are interested in this rare type of tumor.

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  • Paraspinal hibernoma: Grand Round presentation of a rare benign adipocytic tumor
    Soufiane Ghailane, Houssam Bouloussa, Sandra Fauquier, Caroline Ziadé, Olivier Gille
    European Spine Journal.2018; 27(4): 822.     CrossRef
  • Hibernoma Mimicking Atypical Lipomatous Tumor
    Youssef Al Hmada, Inga-Marie Schaefer, Christopher D.M. Fletcher
    American Journal of Surgical Pathology.2018; 42(7): 951.     CrossRef
  • 7,084 View
  • 57 Download
  • 2 Crossref

Clinical Articles

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Minimally Invasive Multilevel Percutaneous Pedicle Screw Fixation for Lumbar Spinal Diseases
Korean J Spine. 2012;9(4):352-357.   Published online December 31, 2012
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Minimally Invasive Multilevel Percutaneous Pedicle Screw Fixation for Lumbar Spinal Diseases
Korean J Spine. 2012;9(4):352-357.   Published online December 31, 2012
Close
Objective

There are rare reports on the result of multilevel (≥3 levels) percutaneous pedicle screw fixation (PPF). The purpose of this study was to report the clinical experiences for multilevel PPF of the lumbar spine.

Methods

A total of 17 patients of lumbar spinal disease (7 degenerative diseases, 6 infectious diseases, and 4 traumatic instabilities) underwent neural decompression and multilevel PPF. There were 8 men and 9 women with a mean age of 61.4 years (range, 25-84) and a mean follow-up period of 23.2 months (range, 13-48). The average PPF level was 3.7. A retrospective review of clinical, radiological, and surgical data was conducted.

Results

"Excellent" or "good" clinical results were obtained in 15 patients (88.2%) according to the Odom's criteria. The average improvement of visual analogue scale was 5.2 points (from 9.3 to 4.1), and the average improvement of Oswestry Disability Index was 36.2 (from 71.2 to 35.0) at the last visit (p<0.05). The fusion rate was 88.2%, but, screw loosening was occurred in 2 patients, and adjacent segmental degeneration was occurred in 2 patients. There was no statistical significance in the change of total lumbar lordotic angle. The average operation time was 5.9 hours, with an estimated blood loss of 550 ml and bed rest duration of 2.0 days.

Conclusion

Although the current study examined a small sample with relatively short term follow up periods, our study results demonstrate that multilevel PPF is feasible and safe for selective lumbar spinal diseases.

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    Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Satoshi Nomura, Masahiko Watanabe
    Journal of Clinical Medicine.2023; 12(21): 6914.     CrossRef
  • Multilevel Percutaneous Fenestrated Screw Fixation with Bone Cement Augmentation in Adult Lumbar Spinal Deformity
    Soo Young Choi, Byung Rhae Yoo, Seong Son, Yong Ahn, Woo Kyung Kim, Sang Gu Lee
    Journal of Minimally Invasive Spine Surgery and Technique.2022; 7(1): 132.     CrossRef
  • Novel C‐arm‐based planning robotic spinal surgery in a cadaver model using quantitative accuracy assessment methodology
    Sangman Park, Hyung Cheol Kim, Yeongha Jeong, Dongyun Kim, Seungjae Ryu, Seongpung Lee, Yongyeob Cha, Sungteac Hwang, Donggi Woo, Hongho Kim, Dong Ah Shin, Yoon Ha, Keung Nyun Kim, Do Heum Yoon, Seong Yi
    The International Journal of Medical Robotics and Computer Assisted Surgery.2022;[Epub]     CrossRef
  • Novel augmentation technique of percutaneous pedicle screw fixation using hydroxyapatite granules in the osteoporotic lumbar spine: a cadaveric biomechanical analysis
    Haruo Kanno, Toshimi Aizawa, Ko Hashimoto, Eiji Itoi
    European Spine Journal.2021; 30(1): 71.     CrossRef
  • Comparative Finite Element Analysis of Lumbar Cortical Screws and Pedicle Screws in Transforaminal and Posterior Lumbar Interbody Fusion
    Dong Ah Sin, Dong Hwa Heo
    Neurospine.2019; 16(2): 298.     CrossRef
  • Enhancing percutaneous pedicle screw fixation with hydroxyapatite granules: A biomechanical study using an osteoporotic bone model
    Haruo Kanno, Toshimi Aizawa, Ko Hashimoto, Eiji Itoi, David Fyhrie
    PLOS ONE.2019; 14(9): e0223106.     CrossRef
  • Facet Joint Fixation and Anterior, Direct Lateral, and Transforaminal Lumbar Interbody Fusions for Treatment of Degenerative Lumbar Disc Diseases: Retrospective Cohort Study of a New Minimally Invasive Technique
    Evgenii Belykh, Andrey A. Kalinin, Nikolay L. Martirosyan, Talgat Kerimbayev, Nicholas Theodore, Mark C. Preul, Vadim A. Byvaltsev
    World Neurosurgery.2018; 114: e959.     CrossRef
  • Facet Fixation Combined with Lumbar Interbody Fusion: Comparative Analysis of Clinical Experience and A New Method of Surgical Treatment of Patients with Lumbar Degenerative Diseases
    V. A. Byvaltsev, A. A. Kalinin, A. K. Okoneshnikova, T. T. Kerimbaev, E. G. Belykh
    Annals of the Russian academy of medical sciences.2016; 71(5): 375.     CrossRef
  • 11,284 View
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  • 8 Crossref

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Traumatic Atlanto-occipital Dislocation (AOD)
Korean J Spine. 2012;9(2):85-91.   Published online June 30, 2012
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Traumatic Atlanto-occipital Dislocation (AOD)
Korean J Spine. 2012;9(2):85-91.   Published online June 30, 2012
Close
Objective

Traumatic atlanto-occipital dislocation (AOD) results from high energy trauma and is an uncommon and usually fatal injury due to an injury to the cervicomedullary junction. Recently, improved prehospital management, early diagnosis and effective treatment led to increasing reports of survival. This study of patients with AOD initial imaging modalities recognizes the clinical features and diagnostic considerations for a quick diagnosis.

Methods

In this article, five survived adult patients with traumatic AOD are presented and retrospectively reviewed. Diagnosis was made by lateral cervical spine x-ray, cervical computed tomography (CT), or magnetic resonance imaging(MRI). Treatment consisted of early immobilization, respiratory support, and subsequent occipitocervical fusion.

Results

Four patients were male and the other one was female. Three were diagnosed early and the others were delayed in confirmations. One was type I AOD and four were type II AOD. All patients were applied occipitocervical fusion. Two cases were worse; neurological states and the other three that showed no change. Lateral X-ray film of all patients in the prevertebral soft tissue swelling at the C2 level was noted. The mean thickness of prevertebral soft tissue C2 level was 17.88 mm(15.18 to 20.17mm). Two were in the normal range of dens-basion index(DBI), three showed abnormalities, and Power's ratio was abnormal in 3 patients.

Conclusion

As for damages caused by a strong external force in patients with severe prevertebral soft tissue swelling at C2 level abnormaly, the doctor determines whether more should be carefully AOD and considers 3D CT or MRI to confirm AOD in these patients.

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  • A comprehensive analysis of traumatic atlanto-occipital and atlanto-axial dislocations: A case series from a level one trauma center
    Henry Krasner, Sukanta Maitra, Allison G. McNickle
    Trauma & Case Reports.2025; 60: 101251.     CrossRef
  • Automated Segmentation and Diagnostic Measurement for the Evaluation of Cervical Spine Injuries Using X-Rays
    Jae Hyuk Shim, Woo Seok Kim, Kwang Gi Kim, Gi Taek Yee, Young Jae Kim, Tae Seok Jeong
    Journal of Imaging Informatics in Medicine.2024; 37(4): 1863.     CrossRef
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Comparative Analysis of Adjacent Levels of Degeneration and Clinical Outcomes Between Conventional Pedicle Screws and Percutaneous Pedicle Screws in Treatment of Degenerative Disease at L3-5; A Preliminary Report
Korean J Spine. 2012;9(2):66-73.   Published online June 30, 2012
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Comparative Analysis of Adjacent Levels of Degeneration and Clinical Outcomes Between Conventional Pedicle Screws and Percutaneous Pedicle Screws in Treatment of Degenerative Disease at L3-5; A Preliminary Report
Korean J Spine. 2012;9(2):66-73.   Published online June 30, 2012
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Objective

This study was conducted to compare radiologic changes and clinical outcomes in adjacent level of percutaneous pedicle screws with those of conventional (open) pedicle screws.

Methods

From January 2007 to December 2009, 51 patients underwent L3-5 decompression and spinal fusion. Percutaneous pedicle screws were used in 22 patients, and open pedicle screws were used in the remaining patients. For estimation of instability, we performed measurements of change in the lordotic and adjacent segment angles. A retrospective evaluation of the patients' data and several assessment scales was conducted for determination of clinical outcomes.

Results

The radiological examinations revealed no significant differences, except the L2-3 sagittal angle change. The upper adjacent level angle change in the open group was larger than that in the percutaneous group. In the percutaneous group, the sagittal angle changed from 9.7±3.0° to 11.25±3.6° during the follow-up periods, and in the open group, the sagittal angle changed from 10.8±4.1° to 13.6±4.5°. Radiological instability was observed in 5 patients (17%) in the open group and in 2 patients (9%) in the percutaneous group. Both groups showed similar clinical outcomes.

Conclusion

We suggest that open screws have a greater tendency to cause degenerative change in the upper segment than percutaneous screws. This may be because percutaneous screw fixation causes minimal injury to supporting structures and preserves adjacent facet joints.

Citations

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    Bioengineering.2024; 11(2): 164.     CrossRef
  • Comparative Analysis of ABM/P-15, Bone Morphogenic Protein and Demineralized Bone Matrix after Instrumented Lumbar Interbody Fusion
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    Journal of Korean Neurosurgical Society.2022; 65(6): 825.     CrossRef
  • Revision Surgery for Short Segment Fusion Influences Postoperative Low Back Pain and Lower Extremity Pain: A Retrospective Single-Center Study of Patient-Based Evaluation
    Takashi Hirai, Toshitaka Yoshii, Hiroyuki Inose, Tsuyoshi Yamada, Masato Yuasa, Shuta Ushio, Satoru Egawa, Keigo Hirai, Atsushi Okawa
    Spine Surgery and Related Research.2018; 2(3): 215.     CrossRef
  • Paraspinal Muscle Sparing Versus Percutaneous Screw Fixation: A Comparative Enzyme Study of Tissue Injury during the Treatment of L4-L5 Spondylolisthesis
    Dong Am Park, Seok Won Kim, Sung Myung Lee, Chang Il Ju, Chong Gue Kim, Suk Jung Jang
    Korean Journal of Spine.2012; 9(4): 321.     CrossRef
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Long-term Follow-up (Minimum 5 Years) Study of Single-level Posterior Dynamic Stabilization in Lumbar Degenerative Disease; 'Interspinous U' & 'DIAM'
Korean J Spine. 2012;9(2):102-107.   Published online June 30, 2012
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Long-term Follow-up (Minimum 5 Years) Study of Single-level Posterior Dynamic Stabilization in Lumbar Degenerative Disease; 'Interspinous U' & 'DIAM'
Korean J Spine. 2012;9(2):102-107.   Published online June 30, 2012
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Objectives

Recently posterior dynamic stabilizations (PDS) are increased in degenerative lumbar disease. But, some previous studies had doubts its long term prognosis. Long term clinical and radiological results of PDS using interspinous device (Interspinous U, DIAM) were analyzed.

Methods

We have used the 'interspinous U' and 'DIAM' for patients with lumbar spinal stenosis. We included single level lumbar spinal stenosis patients who completed minimum 60 months follow-up evaluation. All patients checked plain lateral and flexion-extension views at immediately after the surgery and each follow-up. The clinical outcome was measured by Odom's criteria. Complications including post operative infection, bony erosion, device fracture, device malformations, and instabilities were surveyed.

Results

We included 18 for 'Interspinous U' and 7 patients 'DIAM' groups. Mean follow-up durations for 'Interspinous U' and 'DIAM' were 74.6 and 62.6 months, respectively. Satisfactory groups were 50.0% and 42.9 % for 'Interspinous U' and 'DIAM' groups. In 'Interspinous U' group disc height ratio increased transiently in immediate postoperative period (from 0.18 to 0.21) and then, decreased significantly in last follow-up (0.18). In 'DIAM' group, disc height ratio increased transiently in immediate postoperative period (from 0.18 to 0.19), and then decreased significantly in the last follow-up (0.16). Three (16.7%) and two (28.6%) patients undergo on a re-operation due to severe back pain in 'Interspinous U' and 'DIAM' groups.

Conclusion

Long term follow up 'Interspinous U' and 'DIAM' group showed low patient satisfaction and poor radiological outcomes. To ascertain the benefit of PDS compare with posterior screw fixation, prospective analysis with larger population and multi-center study will be needed.

Citations

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  • Anatomical parameters alter the biomechanical responses of adjacent segments following lumbar fusion surgery: Personalized poroelastic finite element modelling investigations
    Mohammad Nikkhoo, Wen-Chien Chen, Meng-Ling Lu, Chen-Ju Fu, Chi-Chien Niu, Hen-Yu Lien, Chih-Hsiu Cheng
    Frontiers in Bioengineering and Biotechnology.2023;[Epub]     CrossRef
  • Comparative biomechanical analysis of rigid vs. flexible fixation devices for the lumbar spine: A geometrically patient-specific poroelastic finite element study
    Kinda Khalaf, Mohammad Nikkhoo
    Computer Methods and Programs in Biomedicine.2021; 212: 106481.     CrossRef
  • Functional and radiographic evaluation of an interspinous device as an adjunct for lumbar interbody fusion procedures
    Anna Spicher, Werner Schmoelz, Rene Schmid, Hannes Stofferin, Niall J.A. Craig
    Biomedical Engineering / Biomedizinische Technik.2020; 65(2): 183.     CrossRef
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    Ben Roitberg, Mehmet Zileli, Salman Sharif, Carla Anania, Maurizio Fornari, Francesco Costa
    World Neurosurgery: X.2020; 7: 100078.     CrossRef
  • Three-Dimensional Volumetric Changes and Clinical Outcomes after Decompression with DIAM™ Implantation in Patients with Degenerative Lumbar Spine Diseases
    Cheng-Yu Li, Mao-Yu Chen, Chen-Nen Chang, Jiun-Lin Yan
    Medicina.2020; 56(12): 723.     CrossRef
  • Dynamic fixation of the lumbar spine dynamic fixation of the lumbar spine
    V. A. Byvaltsev, A. A. Kalinin, Yu. Ya. Pestryakov, M. A. Aliev
    N.N. Priorov Journal of Traumatology and Orthopedics.2019; 26(2): 43.     CrossRef
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Radiologic Adjacent Segment Degeneration: Two Levels fusion (L3-4-5 and L4-5-S1) Using Percutaneous Pedicle Screw Fixation in Degenerative Lumbar Spinal Disease; A Preliminary Report.
Korean J Spine. 2011;8(3):190-196.
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Radiologic Adjacent Segment Degeneration: Two Levels fusion (L3-4-5 and L4-5-S1) Using Percutaneous Pedicle Screw Fixation in Degenerative Lumbar Spinal Disease; A Preliminary Report.
Korean J Spine. 2011;8(3):190-196.
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OBJECTIVE
The purpose of this study is to examine radiological adjacent segment degeneration (ASD) and clinical results after two levels percutaneous pedicle screw fixation.
METHODS
From 2007 to 2009, 34 patients who underwent percutaneous pedicle screw fixation on L3-4-5 or L4-5-S1 for lumbar degenerative disorders were selected. According to the presence of radiological ASD, ASD group and non-ASD group were compared for clinical results and radiologic results such as total lordotic angle (TLA), segmental lordotic angle (SLA) via lumbar X-rays during follow up periods. Furthermore, we compared pre-operative degree of disc degeneration at adjacent segment between two groups via MRI.
RESULTS
The mean follow-up period and mean age were 27.38+/-9.45 months and 59.21+/-12.73 years. ASD group were 7 patients, and non-ASD group were 27 patients. The mean age of the ASD group (67.40+/-4.81) was significantly older than that of the non-ASD group (57.46+/-13.18). Pre-operative disc degeneration of cranial adjacent segment in ASD group were 6 patients (25.9%), whereas that in non-ASD group were 4 patients (14.8%), showing that preoperative disc degeneration was significantly more severe in the ASD group.
CONCLUSION
Percutaneous pedicle screw fixation is favorable technique to prevent ASD for two levels fusion, however, when the patient is old or the preoperative disc degeneration of the adjacent segment is severe, there is the risk of postoperative ASD, and thus special attention should be paid during the follow-up period.
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Early Experience with a PDN (Prosthetic Disc Nucleus) Combined with A Coflex Device for treating Two.level Lumbar Degenerative Disease.
Korean J Spine. 2009;6(4):266-273.
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Early Experience with a PDN (Prosthetic Disc Nucleus) Combined with A Coflex Device for treating Two.level Lumbar Degenerative Disease.
Korean J Spine. 2009;6(4):266-273.
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OBJECTIVE
Discectomy and/or spinal fusion have been the standard treatment options with proven effectiveness to treat degenerative spinal disease. To treat patients with more physiologic effective methods, there have been many efforts to develop various kinds of devices such as posterior dynamic stabilization and disc replacement. We reviewed our early experiences with the combined use of a partial disc replacement device, PDN-Solo(R) (Raymedica, Minneapolis, MN, USA) and an interspinous device, Coflex(R) (Fixanos, Pefonnas, France) in two.level lumbar degenerative disease.
METHODS
A total of 13 patients with two.level lumbar degenerative disease underwent an operation from June 2003 to September 2004. A retrospective review of the clinical and radiological data was conducted for all the cases. The intervertebral disc height, the segmental lordotic angle and the total lumbar lordosis were measured. The clinical outcomes were evaluated by using the visual analogue scale (VAS), the Oswestry disability index (ODI) and MacNab's criteria.
RESULTS
There were nine men and four women (mean age 34.4 years, range 21-64 years). The mean follow up period was 36.6 months (range 36-43 months). The average segmental lordotic angle of the PDN level was changed from 8.96degrees to 8.41degrees and that of the Coflex level was changed from 5.49degrees to 2.95degrees. The total lumbar lordotic angle was decreased from 33.74degrees to 32.40degrees. The intervertebral disc height of the PDN level was changed from 7.56 mm to 8.41 mm and that of the Coflex level was changed from 9.33 mm to 9.89 mm. The average degree of recovery from back pain was 5.6 points (from 8.9 to 3.3) and the average degree of recovery from leg pain was 4.4 points (from 7.5 to 3.1). The average degree of ODI recovery was 41.7 points (from 67.1 to 25.4). According to MacNab's criteria, the results were excellent in 4 patients (30.8%) and good in 7 patients (53.8%).
CONCLUSION
Using the PDN with the Coflex may avoid rigid fixation in specially selected cases with two.level disease, i.e., those patients with spinal stenosis and a herniated lumbar disc. But further biomechanical tests and more longterm follow.up are needed.
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Radiologic Adjacent Segment Degeneration and Clinical Outcome after Two Level Fusion (L3-4-5 and L4-5-S1) in Degenerative Lumbar Spinal Disease.
Korean J Spine. 2010;7(3):143-149.
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Radiologic Adjacent Segment Degeneration and Clinical Outcome after Two Level Fusion (L3-4-5 and L4-5-S1) in Degenerative Lumbar Spinal Disease.
Korean J Spine. 2010;7(3):143-149.
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OBJECTIVE
We retrospectively analyzed correlation of the development of radiologic adjacent segment degeneration (ASD), clinical outcome, and the vertebral level of fusion in two-level posterior lumbar fusion cases. Furthermore, risk factors of ASD were investigated.
METHODS
From 2000 to 2007, a total of 50 patients were evaluated. Their mean age was 55.0 years and mean follow-up period was 52.7 months. The patients were divided into two groups according to the vertebral level of the fused segment. Group I included 35 patients with L3-4-5 fusion, while 15 patients with L4-5-S1 fusion were categorized into group II. The patients were also divided into two groups, according to the development of ASD. Odom's criteria was used to study clinical outcome, and Cobb's angle was used to evaluate radiologic outcome RESULTS: Of 50 patients, radiologic ASD was found in 24 (48.0%) patients. Group I showed 16 (45.7%) patients with ASD, while Group II showed 8 (53.3%) patients with ASD, and they did not show a significant difference in development of ASD and clinical outcome. Clinical outcome of patients with ASD and the ones without ASD did not show significant difference. Meanwhile, patients with ASD were older and showed decrease of the lordotic angle, as well as significant hypermobility in the cranial adjacent segment, during follow-up.
CONCLUSION
Different vertebral regions of fusion in two-level posterior lumbar fusion did not show significant difference in development of radiologic ASD and clinical outcome. In the development of ASD, decrease of the lordotic angle, hypermobility in the cranial adjacent segment and age were significant factors.
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