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"Young-Seok Lee"

Original Article

Degenerative Spinal Diseases

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Incidence and Risk Factors of Postoperative Ileus in Oblique Lumbar Interbody Fusion Surgery: A Retrospective Study
Neurospine. 2025;22(1):222-230.   Published online March 31, 2025
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Incidence and Risk Factors of Postoperative Ileus in Oblique Lumbar Interbody Fusion Surgery: A Retrospective Study
Neurospine. 2025;22(1):222-230.   Published online March 31, 2025
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Purpose
Postoperative ileus (POI) typically occurs after abdominal surgery but can also affect patients undergoing spinal surgery via the lateral retroperitoneal approach, such as oblique lumbar interbody fusion (OLIF). Therefore, this study aimed to investigate the incidence and risk factors associated with POI in OLIF.
Methods
This retrospective study examined a cohort of 465 patients who underwent OLIF from 2015 to 2023. Patient demographics, comorbidities, pre- and postoperative laboratory test results, and perioperative status were assessed. General condition of patients was assessed using the modified frailty index-11 (mFI-11), prognostic nutrition index, and geriatric nutrition risk index. In OLIF, the size and location of the psoas muscle involved in retraction and its relationship with the vertebral body were also investigated.
Results
POI occurred in 19 patients (4%). Lower mFI-11 was linked to a higher risk of POI. While psoas muscle size had no significant effect on the risk of POI, the anterior location of the psoas muscle relative to the vertebral body was associated with a higher occurrence of POI. Multivariate logistic regression analysis of POI identified mFI-11 as the most significant risk factor (p = 0.003).
Conclusion
This study demonstrated that frailty and nutritional status can influence the occurrence of POI after OLIF. Additionally, bowel manipulation associated with the location of psoas muscle and vertebral body was identified as a risk factor. Proper assessment and improvement in patient frailty and nutritional status before surgery can help predict and prevent the occurrence of postoperative POI.

Citations

Citations to this article as recorded by  Crossref logo
  • Development and comparison of machine learning models for predicting postoperative ileus after posterior thoracolumbar fracture surgery
    Yantong Zhang, Renji Zheng, Huiqing Gao, Yingfeng Zhou, Jun Li, Liqiong Chen
    European Spine Journal.2026; 35(3): 1401.     CrossRef
  • Risk factors for prolonged postoperative ileus in elderly patients undergoing laparoscopic radical resection for colorectal cancer
    Huan Liu, Yang Chen, Shi-Gang Guo, Zhu Liu, Yong-Shuai Huang, Zhen-Dong Zhu, Yu-Jie Feng, Qing Yang, Ya-Lei Liu
    World Journal of Gastrointestinal Oncology.2026;[Epub]     CrossRef
  • 6,818 View
  • 117 Download
  • 2 Web of Science
  • 2 Crossref

Review Article

Special Issue on AI & Robotics

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Navigation-Guided/Robot-Assisted Spinal Surgery: A Review Article
Neurospine. 2024;21(1):8-17.   Published online March 31, 2024
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Navigation-Guided/Robot-Assisted Spinal Surgery: A Review Article
Neurospine. 2024;21(1):8-17.   Published online March 31, 2024
Close
The development of minimally invasive spinal surgery utilizing navigation and robotics has significantly improved the feasibility, accuracy, and efficiency of this surgery. In particular, these methods provide improved accuracy of pedicle screw placement, reduced radiation exposure, and shortened learning curves for surgeons. However, research on the clinical outcomes and cost-effectiveness of navigation and robot-assisted spinal surgery is still in its infancy. Therefore, there is limited available evidence and this makes it difficult to draw definitive conclusions regarding the long-term benefits of these technologies. In this review article, we provide a summary of the current navigation and robotic spinal surgery systems. We concluded that despite the progress that has been made in recent years, and the clear advantages these methods can provide in terms of clinical outcomes and shortened learning curves, cost-effectiveness remains an issue. Therefore, future studies are required to consider training costs, variable initial expenses, maintenance and service fees, and operating costs of these advanced platforms so that they are feasible for implementation in standard clinical practice.

Citations

Citations to this article as recorded by  Crossref logo
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    European Journal of Trauma and Emergency Surgery.2026;[Epub]     CrossRef
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    Seokbin Hwang, Suk-Joong Lee, Sungmin Kim
    Electronics.2026; 15(2): 468.     CrossRef
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    S. Vidyadhara, Abhishek Soni, T. Balamurugan, H. S. Chhabra
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  • Robotic Thoracolumbar Pedicle Screw Fixation: A Comprehensive Narrative Review
    Anuj Mundra, Sachin Sharma, Vishal Singh, S. Vidyadhara, Harvinder Singh Chhabra
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    Manish Gupta, Bhavuk Garg
    Indian Spine Journal.2026; 9(1): 72.     CrossRef
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    Premier Journal of Science.2026;[Epub]     CrossRef
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    Sue Min Cho, Xinrui Zou, Laura Fleig, Mathias Unberath
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    Patrick Strube, Alexander Hölzl, Anna-Maria Vogel, Georg Matziolis, Chris Lindemann
    Die Orthopädie.2026;[Epub]     CrossRef
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    Yawen Jiang, Jikui Qian, Ling Zhang, Yan Yu, Liming Cheng, Jinwu Wang, Ying Yao, Shaobai Wang
    International Journal of Surgery.2026; 112(4): 9770.     CrossRef
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    Marc Boutros, Guy Awad, Shaza Hammad, Reina Khatib, Jad Bou Monsef
    European Journal of Orthopaedic Surgery & Traumatology.2026;[Epub]     CrossRef
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  • Minimally invasive spine surgery with endoscopy, navigation, robotics, and artificial intelligence: Clinical evidence and future directions
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    World Journal of Orthopedics.2026;[Epub]     CrossRef
  • Robot-assisted pedicle screw placement in spinal surgery: an updated systematic umbrella review and meta-meta-analysis of comparisons against freehand and navigation-guided techniques
    Yan-Xin Du, Wen-Xi Sun, Luo-Qi Mai, Xin-Yuan Chen, Lu-Lu Li, Hong-Shen Wang, Yong-Peng Lin, Bo-Lai Chen
    EFORT Open Reviews.2026; 11(1): 57.     CrossRef
  • Research Progress on Percutaneous Endoscopic Treatment for Radicular Cervical Spondylosis
    怀忠 周
    Advances in Clinical Medicine.2026; 16(06): 2540.     CrossRef
  • Occupational radiation exposure in spine surgery: organ-specific OSL phantom dosimetry and workload-based risk assessment
    O Warimezgane, M Hilal, M R Mesradi, A Elanique, Y Aguezzoumen, A Saadi, M R Abbari, A Hadaoui
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  • Posterior and Transforaminal Lumbar Interbody Fusion
    Arpan A. Patel, Shaarada Srivatsa, Mark A. Davison, Michael P. Steinmetz
    Neurosurgery Clinics of North America.2025; 36(1): 11.     CrossRef
  • Robotics in orthopaedic surgery: The end of surgery or its future?
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    Knee Surgery, Sports Traumatology, Arthroscopy.2025; 33(3): 793.     CrossRef
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    Technology and Health Care.2025; 33(2): 744.     CrossRef
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    Xianzheng Zhou, Yimiao Chen, Genyuan Miao, Yanchao Guo, Qinhe Zhang, Jianping Bi
    iScience.2025; 28(1): 111509.     CrossRef
  • A systematic review and meta-analysis of radiation exposure in spinal surgeries: Comparing C-Arm, CT navigation, and O-Arm techniques
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  • S8 Navigation system combined with an ultrasonic osteotome for three-dimensional real-time dynamic visualization decompression to reduce postoperative neurological deterioration in thoracic ossification of the ligamentum flavum
    Shuai Li, Jinpeng Du, Xiaohui Wang, Yunfei Huang, Yansheng Huang, Zhen Chang, Liang Yan, Xuefang Zhang, Zhengwei Shi, Zhigang Zhao, Lin Gao, Songchuan Zhao, Baorong He
    European Spine Journal.2025; 34(3): 1004.     CrossRef
  • Robotic pedicle screw placement for minimal invasive thoracolumbar spine surgery: a technical note
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    Esteban Quiceno, Mohamed A. R. Soliman, Asham Khan, Jeffrey P. Mullin, John Pollina
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    Christian Quinones, John Preston Wilson, Deepak Kumbhare, Bharat Guthikonda, Stanley Hoang
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    Expert Review of Medical Devices.2025; 22(5): 405.     CrossRef
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  • 25,332 View
  • 439 Download
  • 60 Web of Science
  • 64 Crossref

Original Article

Minimally Invasive Spinal Surgery SMISS-Neurospine Special Issue

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The Change of Spinal Canal According to Oblique Lumbar Interbody Fusion in Degenerative Spondylolisthesis: A Prospective Observational Study
Neurospine. 2022;19(3):492-500.   Published online May 13, 2022
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The Change of Spinal Canal According to Oblique Lumbar Interbody Fusion in Degenerative Spondylolisthesis: A Prospective Observational Study
Neurospine. 2022;19(3):492-500.   Published online May 13, 2022
Close
Objective
Oblique lumbar interbody fusion (OLIF) involves inserting large cages into the interbody disc space. This expands the spinal canal and neural foramen by stretching the ligament flavum and releasing the facet joint, resulting in indirect neural decompression. Our objective was to investigate the changes in the spinal canal and ligament flavum over time after OLIF.
Methods
This was a prospective observational study involving 30 patients who underwent OLIF L4–5 between 2015 and 2018. In total, 27 of the 30 patients underwent preoperative, early follow-up ( < 5 days), and late follow-up (10–14 months) magnetic resonance imaging to measure the area of the spinal canal and ligament flavum. Based on the results, the patients were divided into subsidence and nonsubsidence groups for further analysis.
Results
After OLIF, the spinal canal area gradually increased during the preoperative, early postoperative, and late postoperative periods (p < 0.001). The thickness and area of the ligament flavum decreased gradually over the same periods (p < 0.001). Low-grade subsidence (2–4.4 mm) did not influence the effects on the spinal canal and ligament.
Conclusion
After OLIF, the spinal canal and ligament flavum gradually change, which is effective for indirect neural decompression. In addition, the effects of low-grade subsidence on the remodeling of the spinal canal and ligament flavum are insignificant.

Citations

Citations to this article as recorded by  Crossref logo
  • Is Congenital Lumbar Spinal Canal Stenosis a Contraindication for Indirect Decompression by Lateral Lumbar Interbody Fusion (LLIF)?
    Weerasak Singhatanadgige, Thada Nashinoros, Teerachat Tanasansomboon, Wicharn Yingsakmongkol, Vit Kotheeranurak, Worawat Limthongkul
    Global Spine Journal.2026; 16(5): 2117.     CrossRef
  • Oblique Lateral Interbody Fusion With Lateral Vertebral Screw Fixation Versus Transforaminal Lumbar Interbody Fusion for Severe Lumbar Stenosis: Results of a Multicenter Randomized Controlled Trial
    Xuefeng Li, Cheng Lin, Tangyiheng Chen, Renjie Li, Dapeng Li, Sheng Song, Huilin Yang, Genlei Chu, Weimin Jiang, Yijie Liu
    Neurosurgery.2026;[Epub]     CrossRef
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    Kyle M M Behrens, Hossein Elgafy
    World Journal of Orthopedics.2025;[Epub]     CrossRef
  • Incidence and Risk Factors of Postoperative Ileus in Oblique Lumbar Interbody Fusion Surgery: A Retrospective Study
    Young-Seok Lee, Myeong Jin Ko, Seung Won Park
    Neurospine.2025; 22(1): 222.     CrossRef
  • Reduction-First Technique of Unilateral Biportal Endoscopy Lumbar Interbody Fusion for Spondylolisthesis
    JinWoo Jung, Man-Kyu Park, Yong Jin Park, Dae-Chul Cho, Young San Ko
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Review Article

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Hemodynamic Management of Acute Spinal Cord Injury: A Literature Review
Neurospine. 2021;18(1):7-14.   Published online November 17, 2020
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Hemodynamic Management of Acute Spinal Cord Injury: A Literature Review
Neurospine. 2021;18(1):7-14.   Published online November 17, 2020
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The goal of acute spinal cord injury (SCI) management is to reduce secondary injuries and improve neurological recovery after its occurrence. This review aimed to explore the literature regarding hemodynamic management to reduce ischemic secondary injury and improve neurologic outcome following acute SCI. The PubMed database was searched for studies investigating blood flow, mean arterial pressure (MAP), and spinal cord perfusion pressure after SCI. The 2013 guidelines of the American Association of Neurological Surgeons/Congress of Neurological Surgeons recommended maintaining MAP at 85–90 mmHg for 7 days after SCI to potentially improve outcome. However, this recommendation was based on weak evidence for neurologic benefit. The maintenance of MAP will typically require vasopressors, which may have their own set of complications. More recently, studies have suggested the potential importance of considering spinal cord perfusion pressure in addition to the MAP. Further research on the hemodynamic management of acute SCI is required to determine how to optimize neurologic recovery. Evidence-based guidelines for hemodynamic management should acknowledge the gaps in knowledge and the limitations of the current literature.

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Clinical Article

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The Safety and Decision Making of Instrumented Surgery in Infectious Spondylitis
Korean J Spine. 2016;13(3):120-123.   Published online September 30, 2016
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The Safety and Decision Making of Instrumented Surgery in Infectious Spondylitis
Korean J Spine. 2016;13(3):120-123.   Published online September 30, 2016
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Objective

Infectious spondylitis is mostly managed by appropriate antibiotic treatment options, and some patients may require surgical interventions. However, surgical interventions that use spinal instrumentation to correct the mechanical instability may be associated with the risk of an increase in the recurrence rate. In this study, we investigated whether spinal instrumentation effects on recurrence of infectious spondylitis.

Methods

The study was conducted as a retrospective study by dividing the subjects into the noninstrumentation surgery and instrumentation surgery groups among a total of 95 patients who had received surgical interventions in infectious spondylitis from 2009 to 2014. The study investigated patient variables such as underlying illness, presumed source of infection, clinical data, laboratory and radiological data, and ultimate outcome, and compared them between the 2 groups.

Results

In the 95 patients, instrumentation was not used in 21 patients but it was used in 74 patients. When the disease involved ≥3 vertebral bodies, lumbosacral level and epidural part, noninstrumentation surgery was mainly conducted, but when the disease involved the thoracic level and psoas muscle part, instrumentation surgery was mainly conducted. However, there were no differences between the 2 groups in terms of the recurrence rate and the incidence of primary failure.

Conclusion

The use of instrumentation in treating infectious spondylitis was determined by the level of involvement and part of the infection, but the use of instrumentation did not cause any increases in the recurrence rate and the incidence of primary failure.

Citations

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Case Report

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An Incidental Finding of a Radiopaque Pill following Cervical Spinal Surgery in a Parkinson's Disease Patient
Korean J Spine. 2015;12(3):153-155.   Published online September 30, 2015
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An Incidental Finding of a Radiopaque Pill following Cervical Spinal Surgery in a Parkinson's Disease Patient
Korean J Spine. 2015;12(3):153-155.   Published online September 30, 2015
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There are previous reports of the identification of radiopaque medications on abdominal X-rays or computed tomography (CT). We describe an interesting case of the incidental identification of a radiopaque medication on cervical spinal CT following cervical spinal surgery. A sixty seven-year-old male patient with Parkinson's disease (PD) visited our emergency center with a C5-6 dislocation and fracture. Surgery was performed with open reduction and pedicle screw fixation through the posterior approach. No abnormal events occurred during the perioperative period. However, a radiopaque incidental foreign body in front of the C6 vertebrae was found on a cervical spinal CT and X-rays that were performed as routine examinations on postoperative day 3. After 6 hours, we performed gastrofibroscopy (GFS) but were unable to find anything. Therefore, we checked all of his medications related to the neck and check X-ray again. One enteric-coated pill he had taken exhibited strong radiodensity. Although our patient underwent an unnecessary GFS, every spinal surgeon should keep in mind that radiopaque pills can appear similar to spinal instruments on X-ray and CT. In addition, we should also know the associated dysphagia is a possible cause of the delayed passage of medicine in PD with or without cervical osteophytes.

Citations

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  • Pill retention in Parkinson’s disease presenting as a soft tissue mass
    Madeleine Jade Wilson, Bilal Hafeez, Alistair John Tinson
    BMJ Case Reports.2025; 18(12): e267473.     CrossRef
  • Comparison between Anterior Cervical Decompression with Fusion and Posterior Cervical Fusion with Wide Facetectomy for Treatment of Severe Bony Foraminal Stenosis
    Subum Lee, Dae-Chul Cho, Haemin Chon, Sung Woo Roh, Il Choi, Jin Hoon Park
    Journal of Korean Neurosurgical Society.2021; 64(4): 552.     CrossRef
  • Posterior Facetectomy with Fusion Using a Pedicle Screw for Parallel-shaped Cervical Foraminal Stenosis
    Jae yeon Park, Il Choi, Hae min Chon, Jung Hee Kim, Su bum Lee, Jin Hoon Park
    Korean Journal of Neurotrauma.2020; 16(2): 216.     CrossRef
  • Minimally Invasive Cervical Pedicle Screw Placement With a Freehand Technique Through the Posterolateral Approach Using a Tubular Retractor: A Technical Note
    Subum Lee, Jin Hoon Park
    Operative Neurosurgery.2019; 17(4): E166.     CrossRef
  • Dysphagia in Parkinson's Disease
    Sonoko Nozaki
    The Japanese Journal of Rehabilitation Medicine.2019; 56(3): 195.     CrossRef
  • Cervical Spondyloptosis Successfully Treated with Only Posterior Short Segment Fusion Using Cervical Pedicle Screw Fixation
    Min Woo KIM, Su Bum LEE, Jin Hoon PARK
    Neurologia medico-chirurgica.2018;[Epub]     CrossRef
  • 13,461 View
  • 80 Download
  • 6 Crossref

Clinical Article

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Risk Factors and Incidence for Peripheral Arterial Disease in Patients with Typical Lumbar Spinal Stenosis
Korean J Spine. 2014;11(3):183-187.   Published online September 30, 2014
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Risk Factors and Incidence for Peripheral Arterial Disease in Patients with Typical Lumbar Spinal Stenosis
Korean J Spine. 2014;11(3):183-187.   Published online September 30, 2014
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Objective

Intermittent claudication (IC) is a typical symptom of peripheral arterial disease (PAD) and lumbar spinal stenosis (LSS). In order to prevent misdiagnosis of vascular disease, it is important to know the incidence of and risk factors for PAD in patients with LSS. Therefore, the aim of our study was to evaluate the incidence of and risk factors for PAD in patients with typical and severe LSS who underwent spinal surgical treatment.

Methods

The occurrence of PAD was examined retrospectively in 171 consecutive patients with LSS and severe IC who underwent surgical treatment at our hospital from June 2012 to June 2013. Data were collected on background characteristics (sex, age) and known risk factors for PAD, such as hypertension, diabetes mellitus, smoking, hyperlipidemia, stroke, and ischemic heart disease.

Results

Of the 171 patients enrolled, 7 had an abnormal ankle-brachial index (ABI). Computed tomography angiography (CTA) was performed in these patients, and a final diagnosis of PAD was established for all 7 patients. The incidence of PAD in all patients with LSS was 4.1%(7 of 171). Stroke and ischemic heart disease were significantly more common in the LSSPAD group compared with the LSS group. Multiple logistic regression analyses with a forced-entry method revealed that age and stroke (p<0.05) were independent risk factors for PAD.

Conclusion

To prevent misdiagnosis of fatal PAD, we recommend ABI be assessed in patients with LSS and history of stroke.

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    Journal of Clinical Medicine.2022; 11(19): 5550.     CrossRef
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    Luke Boylan, Craig Nesbitt, Lesley Wilson, John Allen, Andrew Sims, Ina Guri, Philip Mawson, Crispian Oates, Gerard Stansby, On Behalf of the NOTEPAD Investigators
    Angiology.2021; 72(5): 474.     CrossRef
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    Musa Güneş, Tarık Özmen, Tuğba Moralı Güler
    The Korean Journal of Pain.2021; 34(4): 471.     CrossRef
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    Christy Tomkins-Lane, Markus Melloh, Arnold Wong
    European Spine Journal.2020; 29(9): 2188.     CrossRef
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    Hidekazu Tanaka, Yutaka Ito, Kunio Yokoyama, Makoto Yamada, Masashi Yamashita, Akira Sugie, Masahiro Kawanishi
    Spinal Surgery.2020; 34(2): 169.     CrossRef
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    Daniel Kyle, Luke Boylan, Lesley Wilson, Shona Haining, Crispian Oates, Andrew Sims, Ina Guri, John Allen, Scott Wilkes, Gerry Stansby
    Journal of Primary Care & Community Health.2020;[Epub]     CrossRef
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    Ayaka Haruta‐Tsukamoto, Hideki Funahashi, Yu Miyahara, Tomoko Matsuo, Toshikazu Nishimori, Yasushi Ishida
    Clinical Case Reports.2018; 6(2): 380.     CrossRef
  • Cauda Equina Conduction Time Determined by F-Waves in Normal Subjects and Patients With Neurogenic Intermittent Claudication Caused by Lumbar Spinal Stenosis
    Yasuaki Imajo, Tsukasa Kanchiku, Hidenori Suzuki, Masahiro Funaba, Norihiro Nishida, Kazuhiro Fujimoto, Toshihiko Taguchi
    Journal of Clinical Neurophysiology.2017; 34(2): 132.     CrossRef
  • The Effect of Lumbar Spinal Stenosis on Results of Treatment in Peripheral Arterial Disease
    Chung-Shik Shin, Byeong-Yeol Choi, Seung-Bum Park, Kyung-Tae Kim, Tae-Ho Kim, Chul-Seung Kim, Kyu-Dam Han
    Journal of the Korean Orthopaedic Association.2016; 51(5): 357.     CrossRef
  • 12,470 View
  • 67 Download
  • 11 Crossref