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"Conservative treatment"

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Indications for Nonsurgical Treatment of Thoracolumbar Spine Fractures: WFNS Spine Committee Recommendations
Neurospine. 2021;18(4):713-724.   Published online December 31, 2021
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Indications for Nonsurgical Treatment of Thoracolumbar Spine Fractures: WFNS Spine Committee Recommendations
Neurospine. 2021;18(4):713-724.   Published online December 31, 2021
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Thoracolumbar spine is the most injured spinal region in blunt trauma. Literature on the indications for nonoperative treatment of thoracolumbar fractures is conflicting. The purpose of this systematic review is to clarify the indications for nonsurgical treatment of thoracolumbar fractures. We conducted a systematic literature search between 2010 to 2020 on PubMed/MEDLINE, and Cochrane Central. Up-to-date literature on the indications for nonoperative treatment of thoracolumbar fractures was reviewed to reach an agreement in a consensus meeting of WFNS (World Federation of Neurosurgical Societies) Spine Committee. The statements were voted and reached a positive or negative consensus using the Delphi method. For all of the questions discussed, the literature search yielded 1,264 studies, from which 54 articles were selected for full-text review. Nine studies (4 trials, and 5 retrospective) evaluating 759 participants with thoracolumbar fractures who underwent nonoperative/surgery were included. Although, compression type and stable burst fractures can be managed conservatively, if there is major vertebral body damage, kyphotic angulation, neurological deficit, spinal canal compromise, surgery may be indicated. AO type B, C fractures are preferably treated surgically. Future research is necessary to tackle the relative paucity of evidence pertaining to patients with thoracolumbar fractures.

Citations

Citations to this article as recorded by  Crossref logo
  • Return to duty after non-surgical treatment of a non-neurological thoracic or lumbar spine fracture in French military patients: a retrospective analysis of 54 patients
    J-B Lines, P J Cungi, C Da Silva, L Aigle, A Dagain, C Joubert
    BMJ Military Health.2026; 172(3): 225.     CrossRef
  • Return to Work After Isolated Spinal Injury: Rates, Predictors, and Implications for Occupational Reintegration
    Philipp Raisch, Tabea Hirth, Michael Kreinest, Sven Y. Vetter, Paul A. Grützner, Matthias K. Jung von Landenberg
    Journal of Occupational Rehabilitation.2026;[Epub]     CrossRef
  • Thoracolumbar burst fractures: robot-assisted mono-segment fixation with vertebral body grafting versus short-segment fixation — a propensity score-matched cohort study
    Junjie Qiao, Yuyu Fan, Ruizhao Zhao, Xinyao Lv, Xiutong Fang
    European Spine Journal.2026;[Epub]     CrossRef
  • Multifunctional MoS₂-PMMA bone cement with enhanced strength and antibacterial activity to overcome limitations of conventional materials in orthopedic surgery
    Changsheng Gong, ShengBo Shi, ZiJing Zhang, ZeTian Zhao, Zuo Liu, Zhe Wang, Xiaobing Yu
    BMC Musculoskeletal Disorders.2026;[Epub]     CrossRef
  • Inkomplette Berstungsfrakturen der thorakolumbalen Wirbelsäule
    Alexander Wengert, Philipp Schleicher, Andreas Pingel, Jonathan Neuhoff, Frank Kandziora
    Die Wirbelsäule.2026; 10(02): 107.     CrossRef
  • Operative versus Conservative Management of AO Spine A3 and A4 Thoracolumbar Burst Fractures: A Systematic Review of Outcomes, Risk Factors, and Anatomical Level
    Maximilian Weber, Jan Hockmann, Tamara Babasiz, Peer Eysel, Lars Peter Müller, Sebastian Wegmann
    World Neurosurgery.2026; 210: 124995.     CrossRef
  • Off-label use of teriparatide for the treatment of a vertebral burst fracture in a young patient: A case report and literature review
    Tiziano Villa, Vincenzo Zottola, Carlo Mariani, Alberto Borgonovo, Luciano Redenti
    Trauma Case Reports.2025; 55: 101127.     CrossRef
  • Outcome characteristics of surgical management of single-level junctional thoracolumbar fractures by short segment posterior transpedicular fixation in selected patients
    Sajad Hussain Arif, Khurram Khan, Mohsin Fayaz, Abrar Ahad Wani, Sarabjit Singh Chibber, Nayil Khursheed Malik, Zulfikar Ali
    Journal of Craniovertebral Junction and Spine.2025; 16(1): 77.     CrossRef
  • Percutaneous Treatment of Traumatic A3 Burst Fractures of the Thoracolumbar Junction Without Neurological Impairment: The Role of Timing and Characteristics of Fragment Blocks on Ligamentotaxis Efficiency
    Mario De Robertis, Leonardo Anselmi, Ali Baram, Maria Pia Tropeano, Emanuela Morenghi, Daniele Ajello, Giorgio Cracchiolo, Gabriele Capo, Massimo Tomei, Alessandro Ortolina, Maurizio Fornari, Carlo Brembilla
    Journal of Clinical Medicine.2025; 14(8): 2772.     CrossRef
  • BOOTStrap-SCI: Beyond One Option of Treatment for Spinal Trauma and Spinal Cord Injury: Consensus-Based Stratified Protocols for Intensive Care and Surgical Management
    Nicolò Marchesini, Riya Mandar Dange, Andreas K. Demetriades, Oscar Alves, Amos Olufemi Adeleye, Ernest J. Barthélemy, José Castillo, Juan Diego Ciro, Raul Echeverri, Kiwon Lee, Wellingson Paiva, Julio Pozuelos, Martin Aliaga Rocabado, Alvaro Soto, Gene Y
    World Neurosurgery.2025; 200: 124099.     CrossRef
  • EVALUATION OF SPINOPELVIC BALANCE IN PATIENTS WITH THORACOLUMBAR JUNCTION FRACTURES SURGICALLY TREATED WITH SCHANZ SCREWS
    JOÃO GABRIEL BELEGANTE SCALABRIN, ANDRE LUIS SEBBEN, ÁLYNSON LAROCCA KULCHESKI, PEDRO GREIN DEL SANTORO, FELIPE DE NEGREIROS NANNI, JOÃO ELIAS BRAGA, XAVIER SOLER I GRAELLS
    Coluna/Columna.2025;[Epub]     CrossRef
  • A comparative analysis of three distinct approaches for the management of type A1 traumatic thoracolumbar fractures: a retrospective cohort study with a minimum 6-year follow-up
    Jiangtao Wang, Huiming Yang, Mario Ganau, Yuhang Wang, Junxian Miao, Liang Yan, Biao Wang
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • GALLBLADDER DYSFUNCTION AFTER COMPLICATED THORACOLUMBAR SPINE INJURY
    V. A. Kolesnichenko, H. M. Herasymov, R. M. Hrynov, L. M. Dushyk, Y. B. Zakharchenko, N. V. Cherkova
    Bulletin of Problems Biology and Medicine.2025; 1(1): 27.     CrossRef
  • Stress-strain state of a thoracolumbar spine model with a Th12 type A1 vertebral fracture under short-segment pedicle fixation: analysis of compressive loading
    O.S. Nekhlopochyn, V.V. Verbov, Ye.V. Cheshuk, M.Yu. Karpinsky, O.V. Yaresko
    TRAUMA.2025; 26(6): 393.     CrossRef
  • Efficacy and safety of conservative treatment in patients with neurologically intact thoracolumbar burst fractures: a meta-analysis
    A. A. Grin, V. A. Karanadze, A. Yu. Kordonskiy, A. E. Talypov, I. S. Lvov, R. I. Abdrafiev
    Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika).2024; 21(2): 27.     CrossRef
  • The AO Spine Thoracolumbar Injury Classification System and Treatment Algorithm in Decision Making for Thoracolumbar Burst Fractures Without Neurologic Deficit
    Barry T. S. Kweh, Jin Wee Tee, Charlotte Dandurand, Alexander R. Vaccaro, Benneker M. Lorin, Klaus Schnake, Emiliano Vialle, Shanmuganathan Rajasekaran, Mohammad El-Skarkawi, Richard J. Bransford, Rishi M. Kanna, Mohamed M. Aly, Martin Holas, Jose A. Cans
    Global Spine Journal.2024; 14(1_suppl): 32S.     CrossRef
  • Verletzungen der thorakolumbalen Wirbelsäule: Konservative und operative Therapie
    Alexander Wengert, Philipp Schleicher, Andreas Pingel, Jonathan Neuhoff, Frank Kandziora
    Die Wirbelsäule.2024; 08(02): 99.     CrossRef
  • Modelling thoracolumbar fractures in goat vertebrae based on axial compression force
    Firas Febrian, Primadenny Airlangga, Kukuh Hernugrahanto
    Scripta Medica.2024; 55(4): 459.     CrossRef
  • Osteoporose – Definition, Risikoerfassung, Diagnose, Prävention und Therapie (Update 2024)
    Hans Peter Dimai, Christian Muschitz, Karin Amrein, Rosemarie Bauer, Daniel Cejka, Rudolf Wolfgang Gasser, Reinhard Gruber, Judith Haschka, Timothy Hasenöhrl, Franz Kainberger, Katharina Kerschan-Schindl, Roland Kocijan, Jürgen König, Norbert Kroißenbrunn
    Wiener klinische Wochenschrift.2024; 136(S16): 599.     CrossRef
  • Twenty year outcomes following short-segment posterior instrumentation and fusion for thoracolumbar burst fractures: A retrospective observational study
    Yigit Kultur, İlker Sarikaya, Mahmut Kursat Ozsahin, Cumhur Deniz Davulcu, Onder Aydingoz
    Medicine.2024; 103(46): e40579.     CrossRef
  • A Systematic Review of the Long-Term Outcomes of Surgical Versus Non-surgical Management for Types A3 and A4 Thoracolumbar Spinal Fractures With No Neurological Deficits
    Sultan A Alfaedi, Abdullah M Alharbi, Abdulrahman S Hassan, Faris A AlZahrani, Jawad Albashri, Ahmed S Albashri, Anas Alqahtani, Mohammed Hariri
    Cureus.2024;[Epub]     CrossRef
  • Diagnosis of Acute Versus Chronic Thoracolumbar Vertebral Compression Fractures Using CT Radiomics Based on Machine Learning: a Preliminary Study
    Xiangrong Zhuang, Jinan Wang, Jianghe Kang, Ziying Lin
    Journal of Imaging Informatics in Medicine.2024; 38(4): 2183.     CrossRef
  • Reliability and repeatability of a modified thoracolumbar spine injury classification scoring system
    Wen-jie Lu, Jiaming Zhang, Yuan-guo Deng, Wei-yu Jiang
    Frontiers in Surgery.2023;[Epub]     CrossRef
  • Efficacy of a novel percutaneous pedicle screw fixation and vertebral reconstruction versus the traditional open pedicle screw fixation in the treatment of single-level thoracolumbar fracture without neurologic deficit
    Lining Rui, Fudong Li, Cao Chen, Yuan E, Yuchen Wang, Yanhong Yuan, Yunfeng Li, Jian Lu, Shengchang Huang
    Frontiers in Surgery.2023;[Epub]     CrossRef
  • Impact of different surgical and non-surgical interventions on health-related quality of life after thoracolumbar burst fractures without neurological deficit: protocol for a comprehensive systematic review with network meta-analysis
    Lea Lanter, Niklas Rutsch, Sebastian Kreuzer, Christoph Emanuel Albers, Peter Obid, Jonathan Henssler, Gabriel Torbahn, Martin Müller, Sebastian Frederick Bigdon
    BMJ Open.2023; 13(12): e078972.     CrossRef
  • Analysis of the Classification Systems for Thoracolumbar Fractures in Adults and Their Evolution and Impact on Clinical Management
    Bogdan Costachescu, Cezar Eugen Popescu, Bogdan Florin Iliescu
    Journal of Clinical Medicine.2022; 11(9): 2498.     CrossRef
  • A survey on the early management of spinal trauma in low and middle-income countries: From the scene of injury to the diagnostic phase (part II)
    Andreas K. Demetriades, Nicolò Marchesini, Oscar L. Alves, Andrés M. Rubiano, Francesco Sala
    Brain and Spine.2022; 2: 101185.     CrossRef
  • 23,918 View
  • 375 Download
  • 20 Web of Science
  • 27 Crossref

Case Reports

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Spontaneous Remission of a Big Subligamentous Extruded Disc Herniation: Case Report and Review of the Literature
Korean J Spine. 2015;12(1):19-21.   Published online March 31, 2015
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Spontaneous Remission of a Big Subligamentous Extruded Disc Herniation: Case Report and Review of the Literature
Korean J Spine. 2015;12(1):19-21.   Published online March 31, 2015
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Spontaneous Regression of a Big Subligamentous Extruded Disc Herniation: Case Report And Review of The Literature The most efficient method for the treatment of lumbar disc herniation is still controversial. The most important aspect is the application of the suitable conservative or surgical treatment to the right patient at the right time. In lumbar disc herniation patients, one must not precipitate except for cases that require surgical indications as in cauda equina syndrome, evolutive motor deficit and persistence of pain in spite of the narcotics. However, the spontaneous regression mechanism has not been completely determined yet. The proposed hypotheses are; dehydration, retraction of the disc to the hernia in the annulus fibrosis, enzymatic catabolism and phagocytosis. In this study, the case of a patient with huge lumbar disc hernia regressing by itself has been presented and the potential mechanisms of disc regression have been discussed.

Citations

Citations to this article as recorded by  Crossref logo
  • Predictive Factors for Resorption in Lumbar Disc Herniation: A Systematic Review
    Xueqiang Shen, Feng Dai, Zihang Li, Hong Jiang, Jintao Liu, Jianwei Wang, Pengfei Yu
    Journal of Inflammation Research.2026; Volume 19: 1.     CrossRef
  • Case Report: Spontaneous regression of extruded lumbar disc herniation following Chuzhen therapy over 3 years
    Youpeng Hu, Ye-Hui Wang, Wenlong Guo, Shengxin Zhao, Peidong Qing, Shiming Xie, Xiaohong Fan
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • Clinical Characteristics of Minimal Lumbar Disc Herniation and Efficacy of Percutaneous Endoscopic Lumbar Discectomy via Transforaminal Approach: A Retrospective Study
    Feifei Chen, Guihe Yang, Jinjin Wang, Zhongpeng Ge, Heran Wang, Yifei Guo, Heng Yang, Xingzhi Jing, Xiaoyang Liu, Xingang Cui
    Journal of Personalized Medicine.2023; 13(3): 552.     CrossRef
  • Disc herniations with spontaneous regression
    Veli ÇITIŞLI
    Acta Medica Alanya.2023; 7(1): 53.     CrossRef
  • Regression of a large prolapsed lumbar disc herniation achieved by conservative treatment: A case report and literature review
    Zhirong Fan, Nengneng Xu, Ji Qi, Haitao Su, Haizhou Wang
    Heliyon.2023; 9(9): e20041.     CrossRef
  • Characteristics and mechanisms of resorption in lumbar disc herniation
    Pengfei Yu, Feng Mao, Jingyun Chen, Xiaoying Ma, Yuxiang Dai, Guanhong Liu, Feng Dai, Jingtao Liu
    Arthritis Research & Therapy.2022;[Epub]     CrossRef
  • Spontaneous regression of a large sequestered lumbar disc herniation: a case report and literature review
    Chengxiang Hu, Baocheng Lin, Zhixing Li, Xiaozhuan Chen, Kun Gao
    Journal of International Medical Research.2021;[Epub]     CrossRef
  • Spontaneous regression of lumbar disc herniations: A retrospective analysis of 5 patients
    K Oktay, KM Ozsoy, UA Dere, NE Cetinalp, M Arslan, T Erman, A Guzel
    Nigerian Journal of Clinical Practice.2019; 22(12): 1785.     CrossRef
  • “Only fixation”: Can it be the single remedy for all?
    Asifur Rahman
    Journal of Craniovertebral Junction and Spine.2019; 10(1): 72.     CrossRef
  • Disc hernia regression as a natural course of discogenic lumbosacral radiculopathy
    M. A. Ivanova, V. A. Parfenov, A. I. Isaikin
    Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova.2018; 118(10): 58.     CrossRef
  • Spontaneous regression of herniated lumbar discs: Report of one illustrative case and review of the literature
    Xiaohui Yang, Qin Zhang, Xiaoning Hao, Xinghua Guo, Liping Wang
    Clinical Neurology and Neurosurgery.2016; 143: 86.     CrossRef
  • Spontaneous Resorption of Intervertebral Disc Herniations
    A. A. Kuleshov, A. I. Krupatkin, N. V. Murav’Yova
    Vestnik travmatologii i ortopedii imeni N.N. Priorova.2016; (3): 81.     CrossRef
  • Spontaneous Resorption of Intervertebral Disc Herniations
    A. A Kuleshov, A. I Krupatkin, N. V Murav’yova
    N.N. Priorov Journal of Traumatology and Orthopedics.2016; 23(3): 81.     CrossRef
  • 9,464 View
  • 114 Download
  • 13 Crossref

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Spontaneous Regression of Lumbar Herniated Intervertebral Disc.
Korean J Spine. 2010;7(1):34-36.
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Spontaneous Regression of Lumbar Herniated Intervertebral Disc.
Korean J Spine. 2010;7(1):34-36.
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Although the spontaneous regression of herniated intervertebral disc(HIVD) is well documented, the most useful and effective treatment protocol for symptomatic HIVD remains controversial. Here, we present a rare case of spon- taneous regression of lumbar HIVD. A 43-year-old woman presented with a pain in her lower back and right lower limb radiating from the buttock to the calf. Straight-leg raising test was positive at 30 degrees on the right side. Magnetic resonance imaging(MRI) revealed right-sided extrusion of an L5-S1 disc fragment with caudal migration; the disc fragment compressed the dural sac and nerve root at this level. The patient refused surgery and was, therefore, managed with conservative therapy comprising bed rest, epidural block, muscle relaxants, and nonsteroidal anti- inflammatory drugs(NSAIDs) for 45 days. At a follow-up after 45 days of this therapy, all the initial symptoms of the patient disappeared completely and a follow-up MRI showed regression of the disc fragment. The exact mecha- nism that prompted this regression is still unclear. However, as shown in our case, lumbar HIVD may spontaneously regress, implying that conservative treatment should be given additional importance in the treatment of HIVD.
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  • 37 Download

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Spontaneous Resolution of Spinal Epidural Hematoma: A Case Report.
Korean J Spine. 2008;5(2):107-109.
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Spontaneous Resolution of Spinal Epidural Hematoma: A Case Report.
Korean J Spine. 2008;5(2):107-109.
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Spinal epidural hematoma(SEH) is not common in lumbar spine disorders and can be developed spontaneously without direct trauma. According to the neurologic deficit and clinical condition of patient, surgical intervention can be required. Authors report a case of spontaneous lumbar SEH resolved spontaneously without surgery. A 59-year-old man had suffered back pain and left leg pain for three weeks without trauma while working on his farm. Magnetic resonance imaging MRI demonstrated a lumbar epidural hematoma at L3/4 level. After 3 months of conservative treatment, his clini- cal symptoms were disappeared completely without neurologic deficit, and the follow-up myelocomputed tomogram(CT) showed complete resolution of the SEH. The primary treatment modality of SEH is surgical evacuation of hema- toma in case of neurologic deterioration, but conservative treatment may be considered if the patient has no neurologic deficit.
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  • 27 Download