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Review Article

Minimally Invasive Surgery

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Toward a Candidate Endoscopic Spine Surgery Registry Framework: Lessons From Global Spine Registry Models
Neurospine. 2026;23(3):605-624.   Published online July 31, 2026
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Toward a Candidate Endoscopic Spine Surgery Registry Framework: Lessons From Global Spine Registry Models
Neurospine. 2026;23(3):605-624.   Published online July 31, 2026
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Objective
Endoscopic spine surgery (ESS) has expanded rapidly, but existing spine registries do not consistently capture ESS-specific technical variables, ultra-early recovery trajectories, selective imaging validation, or dissemination-related learning-curve effects. This review synthesizes established spine registry models, contemporary consensus initiatives, and digital follow-up approaches to propose a candidate ESS-specific registry framework and preliminary Minimum Data Set (MDS) for future validation.
Methods
A structured narrative review was conducted on national and multinational spine registries, relevant consensus initiatives, and digital follow-up models. Sources were reviewed with emphasis on governance, data architecture, workflow design, patient-reported outcome measures (PROMs) integration, follow-up structure, data linkage, validation strategies, and implementation feasibility.
Results
Established registries provide a methodological foundation for benchmarking, complication surveillance, longitudinal PROM capture, and real-world evidence generation. However, ESS requires modular augmentation of existing registry infrastructures to capture approach-specific operative details, early recovery, selective imaging phenotypes, and governance-controlled maturity indicators. The proposed candidate MDS is organized into 4 domains: (1) baseline case-mix and phenotyping, (2) procedure-specific technical and perioperative variables, (3) selective quantitative imaging and morphometric validation, and (4) structured longitudinal outcome surveillance. The framework prioritizes an essential core dataset while separating recommended, optional, research-oriented, and governance-controlled modules, including digitally enabled early follow-up, opioid-related outcomes, radiation exposure, advanced imaging, and learning-curve variables.
Conclusion
A candidate ESS-specific registry framework may support harmonized data capture, real-world evidence generation, quality feedback, and future registry-based research. Formal Delphi consensus, multicenter feasibility testing, and staged integration into existing spine registry infrastructures are required before broader implementation.
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  • 24 Download

Original Articles

Degenerative

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Real-Time Location System Assessment of Early Postoperative Recovery After Lumbar Decompression According to Surgical Approach
Neurospine. 2026;23(2):459-472.   Published online April 30, 2026
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Real-Time Location System Assessment of Early Postoperative Recovery After Lumbar Decompression According to Surgical Approach
Neurospine. 2026;23(2):459-472.   Published online April 30, 2026
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Objective
To evaluate early postoperative mobility after lumbar decompression using real-time location system (RTLS)-derived objective metrics and to explore differences in mobility patterns between biportal endoscopic decompression and open decompression.
Methods
This retrospective cohort study included 323 patients who underwent lumbar decompression for degenerative lumbar spinal stenosis between March 2020 and May 2024. RTLS sensors embedded in wristbands continuously recorded patient mobility during postoperative days (PODs) 1–4. Primary RTLS-derived outcomes included total walking distance, mean walking speed, and active movement ratios (top 20% and top 50%). Between-group comparisons were performed using nonparametric tests. Propensity score matching and multivariable median quantile regression adjusting for age, American Society of Anesthesiologists physical status, and preoperative mobility were conducted.
Results
RTLS identified differences in early postoperative activity patterns between surgical approaches. In adjusted analyses, activity-intensity–based metrics, particularly the top 20% activity ratio, remained significantly higher in the biportal endoscopic decompression group across multiple PODs. Subgroup analyses demonstrated minimal differences after single-level decompression, whereas activity-based differences were more frequently observed in multilevel procedures.
Conclusion
RTLS-based continuous monitoring detected differences in early postoperative activity patterns following lumbar decompression. These findings support the role of RTLS as an objective tool for assessing early functional recovery in spine surgery.
  • 1,175 View
  • 48 Download

Minimally Invasive Surgery

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Beyond the Microscope: Is Endoscopic Discectomy the Next Gold Standard for Lumbar Disc Herniation?
Neurospine. 2026;23(1):61-79.   Published online January 31, 2026
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Beyond the Microscope: Is Endoscopic Discectomy the Next Gold Standard for Lumbar Disc Herniation?
Neurospine. 2026;23(1):61-79.   Published online January 31, 2026
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Objective
This systematic review and meta-analysis aimed to compare endoscopic discectomy (ED) with microdiscectomy (MD) for lumbar disc herniation, evaluating patient-reported outcomes, perioperative parameters, and complications to determine if ED could replace MD as the gold standard.
Methods
Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines, we searched PubMed, Embase, Scopus, and Web of Science (January 2000–June 2025) for randomized controlled trials (RCTs) and prospective cohort studies comparing MD with ED subtypes (transforaminal endoscopic lumbar discectomy [TELD], interlaminar endoscopic lumbar discectomy [IELD], and unilateral biportal endoscopy [UBE]). Outcomes included Oswestry Disability Index (ODI), visual analogue scale (VAS) for pain, operative time, hospital stay, complications, and recurrence. Pooled mean differences and odds ratios (ORs) were calculated using random-effects models, with subgroup analyses by ED subtype. Risk of bias was assessed using RoB 2.0 and ROBINS-I tools.
Results
Seventeen studies (9 RCTs, 8 cohorts; n=3,115) were included. ED significantly reduced hospital stay (mean difference, -2.43 days; 95% CI, -3.62 to -1.23; p<0.05) and showed greater short-term ODI improvement (mean difference, 2.13; 95% CI, 0.58–3.67). No differences were observed in operative time, long-term ODI, or VAS scores. ED had lower wound complications but a higher recurrence risk with TELD (OR, ~2.0). High heterogeneity (I²>95%) and limited long-term data (>2 years) were noted.
Conclusion
ED offers perioperative advantages and comparable efficacy but does not surpass MD due to TELD’s increased recurrence risk. IELD and UBE are promising alternatives, but MD remains the benchmark. Long-term RCTs are needed.

Citations

Citations to this article as recorded by  Crossref logo
  • Letter to Editor: Practice preference of revision surgery for recurrent lumbar disc herniation: an international survey of AO spine members
    Borriwat Santipas, Jin-Sung Kim
    European Spine Journal.2026;[Epub]     CrossRef
  • Domain-Adapted Foundation Models for Single-Click Surgical Instrument Segmentation in Spinal Endoscopy
    Bong-Su Mun, Zhi Zhao, Sang-Min Park, Jiwon Park, Hyun-Jin Park, Hyung Rae Lee, Ho-Joong Kim, Jin S. Yeom
    Neurospine.2026; 23(3): 633.     CrossRef
  • Efficacy and Safety of Fully Endoscopic Interlaminar Lumbar Discectomy in Lumbar Disc Herniation: A 6-month Prospective Analysis
    Baibhav Bhandari, Ajit Kumar, Ravi Shankar Sharma, Girish Kumar Singh, Gaurav Purohit, Shiwam Gupta, Aditya Pal Mahiswar, Sonal Goyal, Kanchan Bisht, Pradeep Atter
    Indian Journal of Pain.2026;[Epub]     CrossRef
  • 6,159 View
  • 163 Download
  • 2 Web of Science
  • 3 Crossref

Technical Note

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Endoscopic Endonasal Transnasopharyngeal Approach for Ventral Craniovertebral Junction Lesions: A Technical Note
Neurospine. 2025;22(3):737-747.   Published online September 30, 2025
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Endoscopic Endonasal Transnasopharyngeal Approach for Ventral Craniovertebral Junction Lesions: A Technical Note
Neurospine. 2025;22(3):737-747.   Published online September 30, 2025
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Objective
Lesions of the ventral craniovertebral junction are difficult to access owing to their deep location and proximity to critical neurovascular and pharyngeal structures. In this study, we aimed to describe the surgical technique and clinical outcomes of the endoscopic endonasal transnasopharyngeal approach for ventral craniovertebral junction lesions and highlight key considerations regarding approach selection, airway management, and occipitocervical stabilization.
Methods
We retrospectively reviewed 7 patients who underwent the endoscopic endonasal transnasopharyngeal approach for ventral craniovertebral junction lesions. The analysis included preoperative planning for surgical access, intraoperative technique, postoperative management, airway and nutritional strategies, and the need for occipitocervical fixation. One representative case is presented to illustrate key technical steps.
Results
Of the 7 patients, 6 had neoplastic lesions and 1 had basilar invagination. Despite a relatively large mean lesion size of 39.4 mm, subtotal or greater resection was achieved in 5 of the 6 tumor cases. Occipitocervical fixation was performed in 2 cases. Two patients underwent prophylactic tracheostomy because of anticipated airway compromise. Of the 5 orally intubated cases, 3 were extubated immediately and 2 by postoperative day 2. Oral feeding resumed by day 10 in 6 cases. No postoperative infections or cerebrospinal fluid leakage occurred. One patient experienced transient velopharyngeal insufficiency, which resolved spontaneously.
Conclusion
The endoscopic endonasal transnasopharyngeal approach is a safe and effective option for ventral craniovertebral junction lesions when appropriately selected. Careful preoperative evaluation and individualized management of airway and spinal stability are essential for favorable outcomes.
  • 8,726 View
  • 53 Download
  • 2 Web of Science

Original Articles

Minimally Invasive Surgery

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Real-Time Water Pressure Monitoring in Unilateral Biportal Endoscopic Spine Surgery
Neurospine. 2025;22(3):812-818.   Published online September 30, 2025
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Real-Time Water Pressure Monitoring in Unilateral Biportal Endoscopic Spine Surgery
Neurospine. 2025;22(3):812-818.   Published online September 30, 2025
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Objective
Unilateral biportal endoscopic (UBE) spine surgery is a minimally invasive technique that uses continuous irrigation to improve visualization and control bleeding. Effective water pressure management is crucial for patient safety, particularly at the cervical and thoracic levels where spinal cord injury risk is higher. However, real-time pressure monitoring remains underexplored. This study evaluates the impact of real-time water pressure monitoring on safety during UBE surgery.
Methods
A prospective study was conducted involving 20 patients undergoing UBE lumbar spine surgery. Patients were divided into 2 groups based on the irrigation system: gravity-based or infusion pump. Real-time water pressure was monitored using a digital sensor throughout surgery. Each procedure was categorized into 3 phases: phase I, working space preparation; phase II, laminectomy; phase III, flavectomy, dura exposure, and discectomy. Data was analyzed according to the type of irrigation system and surgical phase.
Results
The mean water pressure in the surgical field during UBE spine surgery was 17.98± 8.07 mmHg, with no significant differences between surgical phases. However, the infusion pump system maintained significantly lower mean pressure (12.10±3.51 mmHg) compared to the gravity-based system (23.86±6.97 mmHg, p=0.001). The infusion pump system consistently maintained a significantly lower mean water pressure compared to the gravity-based system.
Conclusion
Real-time water pressure monitoring during UBE surgery enhances safety by enabling improved control of pressure within the surgical field. Both the gravity-based and infusion pump systems safely maintained working space pressure, with the pump system showing significantly lower pressure levels.

Citations

Citations to this article as recorded by  Crossref logo
  • Case Report: Spinal epidural lipomatosis with incomplete cauda equina syndrome treated with unilateral biportal endoscopic technique
    Zaiyin Deng, Yujin Wang, Mohammed Saud Shaik, Duanyang Li, Rongjing Di, Zhourui Wu, Bin Ma
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Epidemiology of spinal cord hypertension syndrome in water-mediated uniportal full endoscopic thoracolumbar surgery: a single-center experience
    Haiyang Wu, Luyang Wang, Yiping Zheng, Xizhong Zhu, Wanqi Ren, Ziheng Li, Shoule Ma, Mingwang Zhao, Xingchen Li, Yusheng Xu
    European Spine Journal.2026;[Epub]     CrossRef
  • Controlled versus gravity-based irrigation in endoscopic spine surgery: pressure stability, thresholds, and safety implications
    Rajendra Singh, Thomas Cha, Alexander Vaccaro, Alan Hilibrand, Gregory Schroeder, Gregory Kepler, Afshin Razi, Mitchell Ng
    European Spine Journal.2026;[Epub]     CrossRef
  • Biportal Endoscopic Transforaminal Approach for Midthoracic Calcified Herniated Disc: A Case Report and Technical Note
    Young-Il Ko, Hun-Chul Kim, Jin-Young Lee
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(Suppl 2): S343.     CrossRef
  • Unilateral Biportal Endoscopy Technical Notes in Journal of Minimally Invasive Spine Surgery and Technique 2025: A Structured Analysis of Procedural Trends and Safety Reporting
    Audai Abudayeh, Iakiv Fishchenko, Valentyn Piontkovski
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(Suppl 2): S317.     CrossRef
  • Unilateral biportal endoscopic cervical laminectomy with bilateral foraminotomy for cervical myeloradiculopathy: clinical and radiological outcomes at 1 year
    JinWoo Jung, Sang-Woo Lee, Donghyun Kim, Young San Ko, Dae-Chul Cho, Sang-Kyu Son, Man-Kyu Park
    Neurosurgical Review.2026;[Epub]     CrossRef
  • Gravity-Based vs. Pump-Assisted Irrigation in Unilateral Biportal Endoscopic Decompression for Lumbar Spinal Stenosis: Effects on Operative Efficiency, Clinical Outcomes, and Complications
    Uğur Özdemir, Abdülhalim Akar, Muhammed Fatih Serttaş, Ali Murat Başak, Tunahan Aka
    Medicina.2026; 62(9): 1640.     CrossRef
  • 8,163 View
  • 135 Download
  • 6 Web of Science
  • 7 Crossref

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Intra-, Epidural And Intracranial Pressure Changes During Interlaminar Endoscopy, With and Without Dural Tear
Neurospine. 2025;22(2):583-591.   Published online June 30, 2025
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Intra-, Epidural And Intracranial Pressure Changes During Interlaminar Endoscopy, With and Without Dural Tear
Neurospine. 2025;22(2):583-591.   Published online June 30, 2025
Close
Objective
Endoscopic spine surgery implies possibly severe complications of the central nervous system, from headache to seizures and autonomic dysreflexia. These adverse events might be due to increased intracranial pressure (ICP), presumably induced by increased spinal intra-/epidural pressure caused by fluid irrigation. This study was designed to perform interlaminar endoscopic lumbar discectomy (IELD) at different irrigation fluid settings while monitoring its effect on intra-/epidural and ICPs, with and without dural tears.
Methods
Spinal intradural pressures were measured by introducing catheters through a sacral approach to human cadavers’ lumbar, thoracic, and cervical levels. Additionally, an epidural probe was placed at L3–4. ICP was measured by an intraventricular probe. IELD was performed at L3–4, and the effect of varying irrigation pressures by different endoscopic pump systems and gravity-based irrigation on intra-/epidural and ICP pressures was measured before and after durotomy at L3–4.
Results
Intradural pressure at L3–4 correlated linearly with increasing irrigation pressure, irrespective of the used pump system (median pressure increase at 100-mmHg irrigation pressure: system I: 7 mmHg, r=0.94, p=0.002; system II: 7 mmHg, r=0.89, p=0.017) or gravity (8 mmHg, r=0.93, p=0.242). This effect was also seen intradurally at the thoracic/cervical spine, epidural, and intracranial level, and was even more pronounced with the maneuver of outflow-occlusion and a dural tear present.
Conclusion
While performing IELD, pump pressures correlated linearly to intra-/epidural pressures and ICPs. Pressures did not rise to concerningly high levels without outflow-occlusion, even with increased pump pressures. In the presence of a dural tear, higher pump pressures exacerbated by occlusion may lead to deleterious intradural and ICP elevations.

Citations

Citations to this article as recorded by  Crossref logo
  • Preliminary Report of Full-Endoscopic Spinal Dural Repair Using Double-Arm Sutures With a Biportal Endoscopic System: Technical Note and Feasibility Evaluation in an Ex Vivo Porcine Model
    Kuo-Hua Chao, Chiu-Ming Chen, Jui-Jung Yang
    Operative Neurosurgery.2026; 31(1): 144.     CrossRef
  • Biportal endoscopic foraminotomy of the L7–S1 neuroforamen in dogs: Description of surgical technique and ex vivo comparison with conventional open dorsolateral foraminotomy
    Dimitrios Bekiaridis, Antonio Pozzi, Frank Steffen, Julian Guevar, Lucas A. Smolders
    Veterinary Surgery.2026; 55(4): 837.     CrossRef
  • A Protocol to Preserve the Dural Safety Margin During Simultaneous Hybrid Lumbar Unilateral Biportal Endoscopy and Cervical Laminoplasty
    Karson Tam, H.Y. Li, H.K. Lo, W.L. Kam
    World Neurosurgery.2026; 209: 124877.     CrossRef
  • Epidemiology of spinal cord hypertension syndrome in water-mediated uniportal full endoscopic thoracolumbar surgery: a single-center experience
    Haiyang Wu, Luyang Wang, Yiping Zheng, Xizhong Zhu, Wanqi Ren, Ziheng Li, Shoule Ma, Mingwang Zhao, Xingchen Li, Yusheng Xu
    European Spine Journal.2026;[Epub]     CrossRef
  • Validation of the VIEW score: a novel intraoperative grading scale for visualization in endoscopic spine surgery
    Vit Kotheeranurak, Surachat Jaroenwareekul, Jin-Sung Kim, Christoph Siepe, Don Young Park, Javier Quillo-Olvera, Worawat Limthongkul, Wicharn Yingsakmongkol, Weerasak Singhatanadgige
    European Spine Journal.2026;[Epub]     CrossRef
  • ADAMKIEWICZ’S ARTERY IN ENDOSCOPIC SURGERY: NARRATIVE REVIEW
    Ricardo Rezende Campos, Charbel Jacob Junior, Marcelo Botelho Soares de Brito, Jorge Felipe Ramírez León2, Gabriel Oswaldo Alonso Cuéllar, Sonja Ellen Lobo, João Paulo Machado Bergamaschi
    Coluna/Columna.2026;[Epub]     CrossRef
  • Short term complications and risk factors of unilateral biportal endoscopic cervical spine surgery in patients with cervical radiculopathy and myelopathy: a single center retrospective study
    Chengyue Zhu, Xinning Mao, Zhongshu Shan, Donghao Du, Jiaming Liang, Junfeng Shen, Hao Pan, Wei Zhang, Fangcai Li
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Pneumocephalus with suspected cerebrospinal fluid leakage after epiduroscopic epidural neuroplasty: a case report
    Min Jeong Kang, Bo Kyung Kang, Seung Hee Yoo, Won-joong Kim
    Ewha Medical Journal.2026; 49(3): e23.     CrossRef
  • Biportal Endoscopic Transforaminal Approach for Midthoracic Calcified Herniated Disc: A Case Report and Technical Note
    Young-Il Ko, Hun-Chul Kim, Jin-Young Lee
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(Suppl 2): S343.     CrossRef
  • 7,106 View
  • 179 Download
  • 8 Web of Science
  • 9 Crossref

Minimally Invasive Spine Surgery

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Endoscopic Decompression Combined With Percutaneous Pedicle Screw Fixation for AOSpine A3 or A4 Thoracolumbar Fractures With Neurological Deficits: A Retrospective Cohort Study
Neurospine. 2025;22(2):571-582.   Published online April 30, 2025
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Endoscopic Decompression Combined With Percutaneous Pedicle Screw Fixation for AOSpine A3 or A4 Thoracolumbar Fractures With Neurological Deficits: A Retrospective Cohort Study
Neurospine. 2025;22(2):571-582.   Published online April 30, 2025
Close
Objective
This study aimed to compare the clinical outcomes of patients with AOSpine A3 or A4 thoracolumbar fractures presenting with neurological deficits treated with endoscopic decompression combined with percutaneous pedicle screws fixation (endoscopic minimally invasive surgery, EMIS) or conventional open surgery (OS).
Methods
Data of patients with AOSpine A3 or A4 thoracolumbar fractures with neurological deficits who were treated with EMIS or OS between June 2019 and July 2021 were extracted from the electronic database. Various clinical outcomes were compared between the 2 cohorts.
Results
Among the 231 patients who were followed up for more than 2 years, 107 were in the EMIS cohort and 124 were in the OS cohort. Compared with the OS cohort, the EMIS cohort had longer operative time (p<0.05), but the intraoperative blood loss, incision length and hospital stay were significantly reduced (p<0.05). At both postoperative and final follow-up assessments, the EMIS cohort demonstrated significantly better visual analogue scale and Oswestry Disability Index outcomes compared to the OS cohort (p<0.05). Both cohorts maintained similar correction of spinal canal erosion rate, percentage of anterior vertebral height and sagittal Cobb angle after surgery and at the last follow-up (p>0.05). According to American Spinal Injury Association classification, the 2 cohorts had similar neurological recovery at the last follow-up (p>0.05).
Conclusion
In comparison to OS, EMIS treatment for AOSpine A3 or A4 thoracolumbar fractures with neurological deficits has shown comparable clinical efficacy while significantly reducing surgical trauma.

Citations

Citations to this article as recorded by  Crossref logo
  • Severe trauma care: advances and future directions in diagnostic and therapeutic techniques and information technology support
    Feifei Jin, Shu li, Xuemin Zhang, Wei Huang, Jing Zhou, Zhongdi Liu, Pan Hu, Yanqiu Wu, Zixiao Zhang, Lijun Hou, Xiangjun Bai, Tianbing Wang
    Medical Review.2026; 6(3): 175.     CrossRef
  • 7,665 View
  • 141 Download
  • 1 Crossref

Minimally Invasive Spine Surgery

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Far-Lateral Transforaminal Unilateral Biportal Endoscopic Lumbar Discectomy for Upper Lumbar Disc Herniations
Neurospine. 2025;22(1):14-27.   Published online March 31, 2025
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Far-Lateral Transforaminal Unilateral Biportal Endoscopic Lumbar Discectomy for Upper Lumbar Disc Herniations
Neurospine. 2025;22(1):14-27.   Published online March 31, 2025
Close
Objective
The upper lumbar region has distinctive anatomical characteristics that contribute to the challenges of performing discectomy. We introduce far-lateral transforaminal unilateral biportal endoscopic (UBE) lumbar discectomy for central or paracentral disc herniations in the upper lumbar region.
Methods
We conducted retrospective review of the patients who underwent a far-lateral transforaminal UBE lumbar discectomy at our institution from January 2018 to September 2024. The electronic medical records, operative records, and radiologic images of the patients were reviewed.
Results
A total of 27 patients underwent far-lateral transforaminal UBE lumbar discectomy for central or paracentral disc herniations in the upper lumbar region. The patient had a mean age of 54.0 ± 13.7 years. Operation was performed at the L1–2 level in 3 patients (11.1%), L2–3 in 9 patients (33.3%), and L3–4 in 15 patients (55.6%). The patients were followed-up for a mean of 27.7 ± 19.3 months. The Oswestry Disability Index was significantly decreased from 36.3 ± 6.8 preoperatively to 3.7 ± 3.3 at last follow-up (p < 0.001). The visual analogue scale (VAS) back was significantly decreased from 7.8 ± 0.9 preoperatively to 3.1 ± 0.6 postoperative day 2 (p < 0.001). The VAS leg was significantly decreased from 8.1 ± 0.8 preoperatively to 2.3 ± 0.7 postoperative day 2 (p < 0.001).
Conclusion
The far-lateral transforaminal UBE lumbar discectomy would be a viable surgical option for upper lumbar disc herniations.

Citations

Citations to this article as recorded by  Crossref logo
  • Unilateral Biportal Endoscopic Transforaminal Lumbar Interbody Fusion (TLIF) Using 3-Dimensional-Printed Titanium Cages Compared With Open TLIF: A Comparison of Clinical Outcomes and Fusion Rates
    Sang Hyub Lee, Junghan Seo, Dain Jeong, Sang Youp Han, Dong Hyun Lee, Jae-Won Jang, Dong-Geun Lee, Choon Keun Park
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(Suppl 1): S28.     CrossRef
  • The efficacy and safety of annulus fibrosus suture as adjuvant therapy for lumbar disc herniation: a systematic review and meta-analysis
    Wensi Ouyang, Guimei Guo, Yu Sun, Haobo Jiang, Long Chen, Shaofeng Yang
    Frontiers in Bioengineering and Biotechnology.2026;[Epub]     CrossRef
  • Nerve Root Herniation Due to Delayed Dural Tear Following Unilateral Laminotomy for Bilateral Decompression With Lumbar Discectomy Using Unilateral Biportal Endoscopy
    Sang Hyub Lee, Jae-Won Jang, Yong Eun Cho, Choon Keun Park
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(Suppl 1): S109.     CrossRef
  • Application of the far-lateral approach in uni-portal non-coaxial spinal endoscopic surgery: an evidence-based and Delphi consensus approach among Chinese expert opinions
    Mengchen Yin, Yongpeng Lin, Pengfei Yu, Dong Wang, Fengtao Li, Shiyuan Hao, Kening Sun, Kuankuan Li, Yun Liu, Xin Zhang, Jizheng Li, Mingfei Wang, Junming Ma, Wenlong Yu, Li Xue, Zhilin Li, Guodong Gao, Bo Zhang, Benhui Xu, Jing Feng, Chao Chen, Yiguo Yan
    Brain and Spine.2026; 6: 105994.     CrossRef
  • The influence of the positional relationship between the pedicle and the pars interarticularis on unilateral biportal endoscopy: A retrospective cohort study
    Shaoning Shen, Tingyuan Lai, Hao Wei, Wangnan Mao, Lianguo Wu, Hanbing Zeng
    Medicine.2026; 105(12): e47945.     CrossRef
  • Comparison of short-term clinical efficacy between percutaneous endoscopic transforaminal discectomy and unilateral biportal endoscopy in the treatment of upper lumbar disc herniation
    Jing Zhang, Zhinan Ren, Lei Yu, Cheng Peng, Yingjie Hao
    BMC Musculoskeletal Disorders.2026;[Epub]     CrossRef
  • Incidence and Risk Factors for 30- and 90-day Reoperations Following Biportal Endoscopic Lumbar Discectomy for Single-Level Lumbar Disc Herniations
    Sang Hyub Lee, Jae-Won Jang, Hangyu Lee, Limjoon Yoon, Sejin Song, Dain Jeong, Junghan Seo, Sang Youp Han, Bang-Sang Hahn, Jun Young Kim, Jin Seop Hwang, Dong-Geun Lee, Jin-Sung Kim, Dong Chan Lee, Yong Eun Cho, Choon Keun Park
    Global Spine Journal.2026;[Epub]     CrossRef
  • Clinical Efficacy and Learning Curve of Far‐Lateral Approach (FLA) in Uni‐Portal Non‐Coaxial Spinal Endoscopic Surgery (UNSES) in the Treatment of Lumbar Degenerative Diseases: A Prospective Study
    Mengchen Yin, Wenlong Yu, Yan Lou, Jianfeng Sha, Yang Xue, Dong Zhang, Kaipeng Huang, Kai Lv, Zhichao Ge, Jianmin Li, Jiajun Wu, Hao Sun, Shuqiang Wang
    Orthopaedic Surgery.2026; 18(9): 1972.     CrossRef
  • Bilateral–Contralateral Endoscopic Decompression as a Fusion-Deferral Strategy in Upper Lumbar Stenosis: A Structural Rationale and Conditional Framework—A Technical Note with Cases Review
    Dong Hyun Lee, Sang Yeop Han, Seung Young Jeong, Il-Tae Jang
    Journal of Clinical Medicine.2025; 14(16): 5726.     CrossRef
  • 12,883 View
  • 521 Download
  • 12 Web of Science
  • 9 Crossref

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Transforaminal Endoscopic Thoracic Discectomy Is More Cost-Effective Than Microdiscectomy for Symptomatic Disc Herniations
Neurospine. 2025;22(1):118-127.   Published online March 31, 2025
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Transforaminal Endoscopic Thoracic Discectomy Is More Cost-Effective Than Microdiscectomy for Symptomatic Disc Herniations
Neurospine. 2025;22(1):118-127.   Published online March 31, 2025
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Objective
To analyze costs and cost-effectiveness of transforaminal endoscopic thoracic discectomy (TETD) for the treatment of symptomatic thoracic disc herniation (TDH) and compare it with open microdiscectomy (MD).
Methods
This retrospective cohort study included patients who underwent TETD or MD for symptomatic TDH and had a minimum follow-up of 1 year. Cost analysis included direct costs (primary and secondary hospital costs), indirect costs (lost wages due to work absence), total costs (direct + indirect), and cost-effectiveness (cost per quality-adjusted life year [QALY] and incremental cost-effectiveness ratio [ICER]). Clinical outcomes included patient-reported outcome measures (Oswestry Disability Index [ODI], 36-item Short Form health survey [SF-36]), QALY gained, and reoperation and readmission rates at 1 year. TETD and MD groups were compared for outcome measures.
Results
A total of 111 patients (57 TETD, 54 MD) were included. The direct ($6,270 TETD vs. $7,410 MD, p < 0.01), indirect costs ($1,250 TETD vs. $1,450 MD, p < 0.01), total costs ($7,520 TETD vs. $8,860 MD, p < 0.01), and cost per QALY ($31,333 TETD vs. $44,300 MD, p < 0.01) were significantly lower for TETD compared to MD. ICER of TETD was found to be -$33,500. At 1 year, TETD group showed significantly greater improvement in ODI (46% vs. 36%, p < 0.01) and SF-36 (64% vs. 53%, p < 0.01) and significantly greater QALY gained (0.24 vs. 0.2, p < 0.01) compared to MD group. No significant difference was found in reoperation and readmission rates.
Conclusion
TETD demonstrated significantly better clinical outcomes, lower overall costs, and better cost-effectiveness than MD in appropriately selected patients of symptomatic TDH.

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  • Editorial: Beyond the Portal Wars—Forging a New Consensus in Endoscopic Spine Surgery
    Jin-Sung Kim, Piya Chavalparit
    Global Spine Journal.2026; 16(1): 9.     CrossRef
  • Uniportal Endoscopic Surgery for Thoracolumbar Junction Disc Herniation in a Patient With Myelopathy: A Technical Note and Surgical Video
    Kang Suk Moon, Michel Gustavo Mondragón-Soto, Pedro Leonardo Villanueva-Solórzano
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(1): 155.     CrossRef
  • Measuring Value in Surgery: A Scoping Review of Economic Indices Across Specialties
    Kenneth Nguyen, Emaad Lala, Kento Yamanouchi, Sydney Pattison, Aiyush Bansal, Abhinav Balu, Mir Amaan Ali, Philip K. Louie
    Journal of Surgical Research.2026; 325: 32.     CrossRef
  • Biportal Endoscopic Transforaminal Approach for Midthoracic Calcified Herniated Disc: A Case Report and Technical Note
    Young-Il Ko, Hun-Chul Kim, Jin-Young Lee
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(Suppl 2): S343.     CrossRef
  • 7,851 View
  • 202 Download
  • 6 Web of Science
  • 4 Crossref

Review Articles

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The Utilization of Navigation and Emerging Technologies With Endoscopic Spine Surgery: A Narrative Review
Neurospine. 2025;22(1):105-117.   Published online March 31, 2025
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The Utilization of Navigation and Emerging Technologies With Endoscopic Spine Surgery: A Narrative Review
Neurospine. 2025;22(1):105-117.   Published online March 31, 2025
Close
Endoscopic spine surgery (ESS) is growing in popularity worldwide. An expanding body of literature demonstrates rapid functional recovery with reduced morbidity compared to open techniques. Both full endoscopic spine surgery, or uniportal endoscopy, and unilateral biportal endoscopy (UBE) can be employed in conjunction with various navigation and enabling technologies for assistance with localization of anatomic orientation and assessment of the intraoperative target spinal pathology. This review article describes various navigation technologies in ESS, including 2-dimensional (2D) fluoroscopic imaging, 2D fluoroscopic navigation, 3-dimensional C-arm navigation, augmented reality, and spinal robotics. Employment of enabling navigation and emerging technology with the registration of patient-specific anatomy enables clear delineation of anatomic landmarks and facilitation of a successful procedure. Additionally, avoidance of common pitfalls during use of navigation systems in ESS is discussed in this review.

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  • Lumbar spinal stenosis: current concept of management
    Ji-Won Kwon, Kyung-Soo Suk, Seong-Hwan Moon, Si-Young Park, Namhoo Kim, Sub-Ri Park, Jae-Won Shin, Hak-Sun Kim, Byung Ho Lee
    Asian Spine Journal.2026; 20(1): 143.     CrossRef
  • Delta large-channel endoscopy versus unilateral biportal endoscopy for cervicothoracic junction disc herniation: a prospective randomized controlled trial
    Huaibin Wang, Hui Li, Rushuo Wei, Hao Yan, Ruzhan Yao, Weiqiang Liu, Ling Li
    Journal of Orthopaedic Surgery and Research.2026;[Epub]     CrossRef
  • Intraoperative Dual-Cantilever Probe for Rapid Measurement of Cancellous Bone Compressive Strength Within the Vertebral Body
    Owen Kresse, Evelyn Khong, Gerhardus O. Loohuis, R. Elayne Shelby, Maxwell Boakye, Michael J. Voor, Stuart J. Williams
    Journal of Medical Devices.2026;[Epub]     CrossRef
  • Assisted full-endoscopic spine surgery for lumbar spinal stenosis: Technical note and learning curve
    Koichiro Ono, Daisuke Fukuhara, Yuka Yamami, Yushi Yamaguchi, Kazuma Miura, Yuki Kasuga, Kaichi Sato, Satoshi Takamoto, Naoya Takabayshi, Hiroshi Kawaguchi, Makoto Hirao
    Brain and Spine.2026; 6: 105935.     CrossRef
  • Thoracic Full-Endoscopic Decompression for Ossification of Ligamentum Flavum (OLF) Causing Myelopathy
    Rohit A. Thaker, Smit Kagathara, Pratik Shah
    Indian Spine Journal.2026; 9(1): 112.     CrossRef
  • Real-time Three-dimensional Navigation in Spine Surgery: Is It the Game Changer?
    Shailesh Hadgaonkar, Siddharth Aiyer, Abhinav Bhute, Parag Sancheti
    Indian Spine Journal.2026; 9(1): 37.     CrossRef
  • A retrospective Chinese study on optical–electromagnetic navigation-guided biportal endoscopic unilateral laminotomy for bilateral decompression in lumbar spinal stenosis: improving precision and efficiency
    Xingchen Yao, Junpeng Liu, Li Guan, Jincai Yang, Aixing Pan, Yong Hai
    Asian Spine Journal.2026;[Epub]     CrossRef
  • Robotic-Assisted Uniportal Full-Endoscopic Transforaminal Lumbar Interbody Fusion: A Technical Note on a Hybrid Form of Minimally Invasive Surgery
    Ting Yao Ang, A. Aravin Kumar, Chin Hong Ngai, John J.Y. Zhang, Jacob Y.L. Oh, Ji Min Ling, Thomas C.H. Tan
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(1): 105.     CrossRef
  • O‐Arm Navigation Enhances Facet Preservation Without Compromising Clinical Outcomes in UBE Decompression for Radiographically Stable Adult Degenerative Scoliosis: A Single‐Center Comparative Study
    Yi Liu, Yiwei Xie, Zhibao Chen, Ruijun Xu, Haojie Chen, Xiaojian Ye, Jiangming Yu
    Orthopaedic Surgery.2026; 18(6): 1203.     CrossRef
  • EndoUFM: Utilizing foundation models for monocular depth estimation of endoscopic images
    Xinning Yao, Bo Liu, Bojian Li, Jingjing Wang, Jinghua Yue, Fugen Zhou
    Neural Networks.2026; 203: 109141.     CrossRef
  • Transforaminal Endoscopic Lumbar Discectomy Versus Interlaminar Endoscopic Lumbar Discectomy for Lumbar Disc Herniation: A Systematic Review of Clinical Outcomes, Quality of Life, and Surgical Selection Strategies
    MOHAMMAD RIYAD ABDULWAHID AL-HASNAWI, Hadi Ali Hadi Dala Ali, Rasool Riyadh Abdulwahid Al Hasnawi, Ameer Neamah Saadoon Al-Mhemis, Hinal Alkeshkumar Patel, Oumaima Souilhi, Mustafa Faris Kadhim Kadhim, Mohammed ali modher abduljaleel
    Orthopedic Reviews.2026;[Epub]     CrossRef
  • Establishing navigated UBE in Europe – technical note
    Nicole Lange, Carolin Albrecht, Raimunde Liang, Luisa Mona Kraus, Ghaith Altawalbeh, Shadi Abulhala, Ann-Kathrin Joerger, Bernhard Meyer
    Brain and Spine.2026; 6: 106107.     CrossRef
  • Endoscopic‐Assisted Posterior Atlantoaxial Fusion: Technical Innovation and Clinical Experience
    Jichong Zhu, Chengqian Huang, Jiang Xue, Jiarui Chen, Yufan Xu, Dequan Liu, Xinli Zhan, Chong Liu
    Orthopaedic Surgery.2026; 18(8): 1768.     CrossRef
  • Research Progress on Percutaneous Endoscopic Treatment for Radicular Cervical Spondylosis
    怀忠 周
    Advances in Clinical Medicine.2026; 16(06): 2540.     CrossRef
  • Comparative Clinical and Radiological Outcomes of Arthroscopic‐Assisted Uniportal Spinal Surgery Versus Unilateral Biportal Endoscopy for Unilateral Laminotomy With Bilateral Decompression in Lumbar Spinal Stenosis: A 2‐Year Follow‐Up Study
    Abdul Waheed Bahir, Wang Daxing, Liu Bailian, Gan Xuewen, Xiong Ying, Xiao Jiayu, Gu Shao
    Orthopaedic Surgery.2026; 18(8): 1613.     CrossRef
  • Domain-Adapted Foundation Models for Single-Click Surgical Instrument Segmentation in Spinal Endoscopy
    Bong-Su Mun, Zhi Zhao, Sang-Min Park, Jiwon Park, Hyun-Jin Park, Hyung Rae Lee, Ho-Joong Kim, Jin S. Yeom
    Neurospine.2026; 23(3): 633.     CrossRef
  • Full-endoscopic extraforaminal lumbar discectomy: Use of 3-D image-guidance can mitigate risks and overcome steep learning curve
    Anwesha Dubey, Abhijith R. Bathini, Katherine Anastasi, Joshua Bakhsheshian
    Journal of Clinical Neuroscience.2025; 139: 111455.     CrossRef
  • Navigated Uniportal Endoscopic Decompression for Thoracic Myelopathy Secondary to Ossified Yellow Ligament: A Report of Two Cases
    Bing Wui Ng, Ozlan Izma Muhamed Kamil
    Cureus.2025;[Epub]     CrossRef
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  • 18 Crossref

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Clinical Outcomes and Patient Perspectives in Full Endoscopic Cervical Surgery: A Systematic Review
Neurospine. 2025;22(1):81-104.   Published online March 31, 2025
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Clinical Outcomes and Patient Perspectives in Full Endoscopic Cervical Surgery: A Systematic Review
Neurospine. 2025;22(1):81-104.   Published online March 31, 2025
Close
Objective
Full endoscopic cervical surgery (FECS) is an evolving minimally invasive approach for treating cervical spine disorders. This systematic review synthesizes current evidence on the clinical outcomes and patient perspectives associated with FECS, specifically evaluating its safety, efficacy, and overall patient satisfaction.
Methods
A systematic search of the PubMed/MEDLINE, Cochrane Library, Embase, and Web of Science databases was conducted following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Studies published between January 2000 and September 2024 that reported on clinical outcomes or patient perspectives related to FECS were included. Risk of bias was assessed using the ROBINS-I (Risk Of Bias In Non-randomized Studies - of Interventions) tool and the Cochrane Risk of Bias tool. Inclusion criteria encompassed randomized controlled trials, prospective cohort studies, retrospective studies, and observational studies focused on adult populations undergoing FECS for cervical spine surgery.
Results
The final synthesis included 30 studies. FECS was associated with significant reductions in both cervical and radicular pain, as well as meaningful functional improvements, measured by standardized clinical scales such as the Neck Disability Index and visual analogue scale. Patient satisfaction rates were consistently high, with most studies reporting satisfaction exceeding 85%. Complication rates were low, primarily involving transient neurological deficits that were typically resolved without the need for further intervention. Nonrandomized studies generally presented a moderate risk of bias due to confounding and selection, whereas randomized controlled trials exhibited a low risk of bias.
Conclusion
FECS is a safe and effective minimally invasive surgical option for cervical spine disorders associated with substantial pain relief, functional improvement and high levels of patient satisfaction.

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  • Response to the letter to the editor: Inconsistencies in obesity criteria: implications for systematic reviews on endoscopic spine surgery
    Wongthawat Liawrungrueang, Watcharaporn Cholamjiak, Peem Sarasombath, Yudha Mathan Sakti, Pang Hung Wu, Meng-Huang Wu, Yu-Jen Lu, Lo Cho Yau, Zenya Ito, Sung Tan Cho, Dong-Gune Chang, Kang Taek Lim
    Asian Spine Journal.2026; 20(1): 211.     CrossRef
  • Full-Endoscopic Posterior Cervical Foraminotomy and Discectomy for Cervical Disc Hernia With Unilateral Radiculopathy
    Idris Gurpinar, Mehmet Yigit Akgun, Furkan Almas, Ozkan Ates
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(1): 149.     CrossRef
  • Clinical and Functional Outcomes of Posterior Endoscopic Decompression for Symptomatic Cervical Disc Herniation
    Adam Mahendra Teja, Muhammed Anzar, Cheol Wung Park
    Cureus.2026;[Epub]     CrossRef
  • Ultrasound-guided brachial plexus hydrodissection combined with acupotomy release for the treatment of cervical spondylotic radiculopathy: a multicenter retrospective study
    Xiang Shang, Guo-Rui Luan, Yang-Chun Song, Fen Zhang, San-Bing Wu, Kai Geng, Hou-Shan Fang, Wei Wei, Zhen-Ya Wang, Han-Qing Zhao, Yong-Hui Yang, De-Hong Meng
    Frontiers in Aging Neuroscience.2026;[Epub]     CrossRef
  • Current Trends and Future Directions in Lumbar Spine Surgery: A Review of Emerging Techniques and Evolving Management Paradigms
    Gianluca Galieri, Vittorio Orlando, Roberto Altieri, Manlio Barbarisi, Alessandro Olivi, Giovanni Sabatino, Giuseppe La Rocca
    Journal of Clinical Medicine.2025; 14(10): 3390.     CrossRef
  • Navigated Minimally Invasive Cervical and Cervicothoracic Fixation: A Technical Note on Surgical Technique and Proposed Classification
    Spyridon Komaitis, Konstantinos Zygogiannis, Sotirios Karatzoglou, Dimitrios Klitsinikos, Dritan Pasku, Khalid Salem
    Cureus.2025;[Epub]     CrossRef
  • 15,091 View
  • 227 Download
  • 5 Web of Science
  • 6 Crossref

Original Articles

Minimally Invasive Spine Surgery

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Comparison of 3 Different Endoscopic Techniques for Lumbar Spinal Stenosis: Comprehensive Radiological and Clinical Study
Neurospine. 2025;22(1):276-285.   Published online March 31, 2025
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Comparison of 3 Different Endoscopic Techniques for Lumbar Spinal Stenosis: Comprehensive Radiological and Clinical Study
Neurospine. 2025;22(1):276-285.   Published online March 31, 2025
Close
Objective
This study aimed to compare the clinical and comprehensive radiological outcomes of 3 types of endoscopic decompression surgery: unilateral biportal endoscopic lumbar decompression (UBELD), microendoscopic laminotomy (MEL), and percutaneous endoscopic lumbar decompression (PELD).
Methods
Patients with single-level lumbar spinal stenosis without instability were included in this multicenter retrospective study. Visual analogue scale (VAS) scores for each extremity, VAS back pain, and Japanese Orthopaedic Association (JOA) scores at preoperative and postoperative 1st, 6th, and 12th months were used as clinical outcome measures. In order to compare the radiological results of the patients, bilateral superior articular distance (SAD), bilateral lateral recess height (LR height), bilateral lateral recess angle (LR angle), and cross-sectional spinal canal area values were measured.
Results
Eighty patients in the UBELD group, 73 patients in the MEL group, and 62 patients in the PELD group were included in the study. There was a statistically significant improvement in VAS scores and JOA scores in all groups compared to the preoperative period. At the 12th month postoperatively, the highest lateral decompression values on the approach side were determined as MEL (SAD: 4.1 mm, LR angle: 38.8°, LR height: 4.0 mm), followed by UBELD (SAD: 3.6 mm, LR angle: 36.2°, LR height: 3.3 mm) and PELD (SAD: 3.0 mm, LR angle: 21.7°, LR height: 2.3 mm), respectively. For the contralateral side, the highest lateral recess decompression values were listed as UBELD > MEL > PELD.
Conclusion
Effective decompression can be performed using all endoscopic techniques in lumbar spinal stenosis. However lateral recess decompression values were found to be better in UBELD and MEL techniques, compared to PELD.

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  • Comparison of unilateral biportal endoscopic lumbar interbody fusion (UBE-LIF) and conventional open TLIF in degenerative lumbar spine disease: a radiological, clinical, and laboratory study
    Yunus Şamil Gönüldenk, Mustafa Özyıldıran, Abdullah Merter
    Journal of Orthopaedic Surgery and Research.2026;[Epub]     CrossRef
  • Cost-effectiveness analysis of the early transition from microscopic to biportal endoscopic unilateral laminectomy bilateral decompression
    Sung-Eun Kwon, Hangeul Park, Noah Hong, Woojin Kim, Jungbo Sim, Ho Sung Myeong, Seunghoon Lee, Jun-Hoe Kim, Chang-Hyun Lee, Fon-Yih Tsuang, Chi Heon Kim
    Medicine.2026; 105(34): e50400.     CrossRef
  • Bispectral Index Monitoring in Endoscopic Lumbar Spine Surgery: Retrospective Analysis of Central Nervous System Complications
    Abdullah Merter, Mustafa Özyıldıran, Fatih Kurt, Menekşe Özçelik
    World Neurosurgery.2025; 200: 124230.     CrossRef
  • Comparison of 0-degree and 30-degree endoscopes in unilateral biportal endoscopic decompression for lumbar spinal stenosis: Which preserves the facet joint better?
    Abdullah Merter, Mustafa Özyıldıran
    Journal of Orthopaedic Surgery.2025;[Epub]     CrossRef
  • Cumulative Sum and Risk-Adjusted Cumulative Sum Analysis of the First-Year Learning Curve for Unilateral Biportal Endoscopy in a Neurosurgeon with Endoscopic Skull Base Experience
    Eren Yılmaz, Atakan Emengen, Aykut Gökbel, Ayse Uzuner, Mehmet Korkmaz, Sibel Balci, Abdullah Merter, Savas Ceylan
    World Neurosurgery.2025; 204: 124523.     CrossRef
  • 6,733 View
  • 241 Download
  • 6 Web of Science
  • 5 Crossref

Minimally Invasive Spine Surgery

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Anatomical Importance Between Neural Structure and Bony Landmark in Neuroventral Decompression for Posterior Endoscopic Cervical Discectomy
Neurospine. 2025;22(1):286-296.   Published online March 31, 2025
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Anatomical Importance Between Neural Structure and Bony Landmark in Neuroventral Decompression for Posterior Endoscopic Cervical Discectomy
Neurospine. 2025;22(1):286-296.   Published online March 31, 2025
Close
Objective
This study aims to investigate the anatomical relationship among the nerve roots, intervertebral space, pedicles, and intradural rootlets of the cervical spine for improving operative outcomes and exploring neuroventral decompression approach in posterior endoscopic cervical discectomy (PECD).
Methods
Cervical computed tomography myelography imaging data from January 2021 to May 2023 were collected, and the RadiAnt DICOM Viewer Software was employed to conduct multiplane reconstruction. The following parameters were recorded: width of nerve root (WN), nerve root-superior pedicle distance (NSPD), nerve root-inferior pedicle distance (NIPD), and the relationship between the intervertebral space and the nerve root (shoulder, anterior, and axillary). Additionally, the descending angles between the spinal cord and the ventral (VRA) and dorsal (DRA) rootlets were measured.
Results
The WN showed a gradual increase from C4 to C7, with measurements notably larger in men compared to women. The NSPD decreased gradually from the C2–3 to the C5–6 levels. However, the NIPD showed an opposite level-related change, notably larger than the NSPD at the C4–5, C5–6, and C7–T1 levels. Furthermore, significant differences in NIPD were observed between different age groups and genders. The incidence of the anterior type exhibited a gradual decrease from the C2–3 to the C5–6 levels. Conversely, the axillary type exhibited an opposite level-related change. Additionally, the VRA and DRA decreased as the level descended, with measurements significantly larger in females.
Conclusion
A prediction of the positional relationship between the intervertebral space and the nerve root is essential for the direct neuroventral decompression in PECD to avoid damaging the neural structures. The axillary route of the nerve root offers a safer and more effective pathway for performing direct neuroventral decompression compared to the shoulder approach.

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  • Bone tunnel approach for cervical spondylotic radiculopathy with uncovertebral osteophytes
    Xin Wang, Tao Hu, Bo Lei, Chaofan Qin, Xiang Tan, Changjun Pi, Mingxin Chen, Qingshuai Yu, Si Cheng, Zhengjian Yan
    European Spine Journal.2026; 35(4): 1848.     CrossRef
  • Acute Radiculopathy After Anterior Cervical Discectomy and Fusion of Cervical Spondylotic Radiculopathy with Cervical Kyphosis: Causes and Prevention
    Fan He, Zong-xian Feng, Pei-ming Sang, Shi-rong Gu, Bin-hui Chen
    World Neurosurgery.2026; 206: 124767.     CrossRef
  • 3,785 View
  • 160 Download
  • 2 Web of Science
  • 2 Crossref

Video Articles

Video Articles: Special Issue With JMISST

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Full-Endoscopic J-Shaped Transforaminal L5 Nerve Decompression in Bertolotti Syndrome
Neurospine. 2024;21(4):1131-1136.   Published online December 31, 2024
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Full-Endoscopic J-Shaped Transforaminal L5 Nerve Decompression in Bertolotti Syndrome
Neurospine. 2024;21(4):1131-1136.   Published online December 31, 2024
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This case report and video demonstrate the technique of full-endoscopic J-shaped transforaminal L5 exiting nerve decompression in Bertolotti syndrome. Bertolotti syndrome, characterized by a congenital lumbosacral transitional vertebra, often results in mechanical lower back pain and nerve root compression. A 69-year-old male presented with progressive radiating pain in the right leg and tingling in the L5 dermatome. Lumbar spine MRI revealed a right foraminal disc herniation at the L5–S1 level, with calcification and foraminal stenosis. The patient was also diagnosed with Castellvi type I Bertolotti syndrome, featuring a large L5 transverse process and a high iliac crest. These anatomical variations complicated the transforaminal approach, creating a narrow safety zone for conventional methods. The approach began with docking on the L5 transverse process. Endoscopic drilling was performed in a J-shaped configuration to partially resect the transverse process and alar wing, facilitating endoscope insertion into Kambin’s triangle. Foraminal decompression was achieved by removing the tip of the superior articular process (SAP), thereby decompressing the L5 exiting nerve root. Full-endoscopic spine surgery offers a safe and effective alternative to traditional open techniques for L5 nerve decompression in Bertolotti syndrome. This video presentation illustrates the intraoperative endoscopic approach, detailing the decompression techniques and highlighting the minimally invasive advantages of this method.

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  • L5–S1 Anatomic Features Relevant to Minimally Invasive Decompression and Fusion: A Cadaveric and Imaging-Based Study
    Miguel Relvas-Silva, André Rodrigues Pinho, Vitorino Veludo, Daniel Medina-Dias, António Pereira Rodrigues, Hélio Alves, Maria Dulce Madeira, Pedro Alberto Pereira
    Diagnostics.2026; 16(4): 610.     CrossRef
  • A comparative study of the far lateral approach of uni-portal non-coaxial spinal endoscopic surgery versus percutaneous endoscopic transforaminal discectomy (PETD) for L5/S1 foraminal stenosis with high iliac crest: a retrospective cohort study
    Jie Zhang, Xuanwen Liu, En Song, Dan Chen, Hongda Zhou, Qin Luo
    International Orthopaedics.2026; 50(6): 1435.     CrossRef
  • O-arm navigation-guided uni-portal non-coaxial spinal endoscopic surgery for the precise treatment of far-out syndrome—a case report and literature review
    Kai Lv, Dong Zhang, Xinhe Wang, Qiugen Wang, Zhichao Ge, En Song, Hao Sun, Mencheng Yin, Jiajun Wu, Shuqiang Wang, Jianmin Li
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Full-endoscopic Spine Surgery for the Treatment of Far-out Syndrome: A Case Series
    Ryuichi WATANABE, Ryoji TOMINAGA, Kento TAKEBAYASHI, Yasushi OSHIMA, Hiroki IWAI, Hisashi KOGA
    Neurologia medico-chirurgica.2025; 65(12): 583.     CrossRef
  • 4,555 View
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  • 6 Web of Science
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Video Articles: Special Issue With JMISST

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Full-Endoscopic Resection of a Lumbar Intradural Tumor (Schwannoma): Video Case Report and Description of the Surgical Technique
Neurospine. 2024;21(4):1096-1099.   Published online December 31, 2024
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Full-Endoscopic Resection of a Lumbar Intradural Tumor (Schwannoma): Video Case Report and Description of the Surgical Technique
Neurospine. 2024;21(4):1096-1099.   Published online December 31, 2024
Close
Endoscopic spinal surgery has gained increasing popularity over the past 10 years. Its muscle-preserving nature, reduction in postoperative pain, and lower complication rates have contributed to the growing number of surgeons adopting this technique year after year. This same progression has led to the application of the technique in oncological pathology, primarily for separation surgeries and biopsies of extradural lesions. However, reports in the literature on the use of this technique to treat intradural spinal tumors remain scarce. To present a case report of a patient with an intradural lesion, compatible with schwannoma, successfully removed using a fully endoscopic technique. A 46-year-old female patient presented with a long-standing history of low back pain and bilateral leg pain. The pain worsened over the past few months before her initial presentation. She also reported experiencing weakness in her feet and intermittent hypesthesia in her legs. Magnetic resonance imaging (MRI) showed a small intradural extramedullary tumor at the L1 level. Given the patient’s young age, the tumor location at the thoracolumbar junction, and the rather small tumor size, a full-endoscopic approach was selected and performed. A step-by-step video of the surgical technique is provided with the manuscript. The current follow-up period is 2.5 years, with the patient remaining asymptomatic. The most recent follow-up MRI, conducted 16 months after the surgery, indicated no signs of recurrence. To our knowledge, this is the first video report providing a step-by-step description of this procedure. More high-quality evidence is needed to properly evaluate the safety and outcomes of this technique.

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  • Clinical and surgical outcomes of spinal intradural tumors: A retrospective study
    Birol Özkal
    Ağrı Tıp Fakültesi Dergisi.2026; 4(1): 9.     CrossRef
  • Endoscopic resection of lumbar intradural spinal tumors: A case series on feasibility, safety, and preliminary outcomes
    Facundo Van Isseldyk, Vincent Hagel
    Brain and Spine.2026; 6: 106040.     CrossRef
  • Full Endoscopic Excision of a Large Intradural Extramedullary Tumor: A Technical Note
    Kanthila Mahesha, H. Shatananda Prasad Rao
    Journal of Minimally Invasive Spine Surgery and Technique.2026; 11(1): 124.     CrossRef
  • A Systematic Review of Clinical Outcomes and Technical Considerations: Endoscopic Spine Surgery for Primary Spinal Tumors
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