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"Kyphoplasty"

Original Article

Bone Biology and Osteoporosis Special Issue

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Comparative Efficacy of Surgical Interventions for Osteoporotic Vertebral Compression Fractures: A Systematic Review and Network Meta-analysis
Neurospine. 2023;20(4):1142-1158.   Published online December 31, 2023
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Comparative Efficacy of Surgical Interventions for Osteoporotic Vertebral Compression Fractures: A Systematic Review and Network Meta-analysis
Neurospine. 2023;20(4):1142-1158.   Published online December 31, 2023
Close
Objective
We aimed to comprehensively compare surgical methods for osteoporotic vertebral compression fracture (OVCF) using systematic review and network meta-analysis to understand their effectiveness and outcomes, as current research provides limited overviews.
Methods
We followed PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines, preregistering our protocol with PROSPERO. We analyzed Englishpublished randomized controlled trials (RCTs) on adults with OVCFs that evaluated pain intensity or functionality using tools like visual analogue scale (VAS) or Oswestry Disability Index (ODI). Exclusions included non-RCTs, malignancy-related fractures, and certain interventions. Using the RoB 2 tool, we assessed bias and visualized results with Robvis. Our primary outcome was pain intensity, with secondary outcomes including disability, new fractures, and cement leakage. Results were synthesized using Stata/MP.
Results
Thirty-four RCTs from 10 countries, totaling 4,384 patients, were analyzed. Shortterm VAS indicated kyphoplasty with facet joint injection (KIJ) as the top treatment at 87.7%, while unipedicular kyphoplasty (UKP) led to long-term at 74.9%. Short-term ODI favored vertebroplasty with facet joint injection (VIJ) at 98.4%, with kyphoplasty (KP) leading longterm at 66.0%. All surgical techniques were superior to conservative treatment. Vertebral augmentation devices reported the fewest new fractures and curved vertebroplasty had the least cement leakage. SUCRA (surface under the cumulative ranking) analyses suggested UKP and VIJ as top choices for postoperative pain relief, with VIJ excelling in postoperative disability improvement.
Conclusion
Our analysis evaluates 12 OVCF interventions, underscoring KIJ for short-term pain relief and VIJ and UKP for long-term efficacy. Notably, VIJ stands out in disability outcomes, emphasizing the need for comprehensive OVCF management.

Citations

Citations to this article as recorded by  Crossref logo
  • Diagnosis and treatment of osteoporotic vertebral fractures
    Martin Bibza, Michal Božík, Mário Malina, Boris Šteňo
    Clinical Osteology.2026; 31(1): 55.     CrossRef
  • Predicting long-term clinical mortality of elderly patients with vertebral compression fractures
    Shuofan Wang, Kaiwen Peng, Kaili Peng, Zhichao Gao
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • The bisegmental Cobb angle in osteoporotic spine fractures: Does it influence treatment decision or functional outcome?
    Philipp Schenk, Bernhard W. Ullrich, Felix C. Kohler, Falko Schwarz, Klaus J. Schnake, Michael A. Scherer, Gregor Schmeiser, Katja Liepold, Marion Riehle, Michael Müller, Martin Bäumlein, Sebastian Katscher, Max J. Scheyerer, Georg Osterhoff, Kai Sprengel
    Brain and Spine.2026; 6: 106099.     CrossRef
  • Restoration of Sagittal Alignment and Pulmonary Function With Percutaneous Vertebral Body Augmentation for Painful Osteoporotic Vertebral Compression Fractures: A Systematic Review
    Hanne H Jørgensen, Mikkel Ø Andersen, Tove F Frandsen, Line A Wickstrøm, Benjamin Kostic, Leah Y Carreon
    Cureus.2025;[Epub]     CrossRef
  • Prophylactic Antibiotics in Vertebroplasty and Kyphoplasty: A Nationwide Analysis of Infection Rates and Antibiotic Use in South Korea
    Youngjin Kim, Young-Hoon Kim, Sukil Kim, Jun-Seok Lee, Sang-Il Kim, Joonghyun Ahn, So-Young Han, Hyung-Youl Park
    Antibiotics.2025; 14(9): 901.     CrossRef
  • Spinal Subdural Hematoma After Kyphoplasty in a Patient on Warfarin: A Case Report and Literature Review
    Ho-Young Jung, Jun-Seok Lee, Geon-U Kim, Hyung-Youl Park
    Journal of Advanced Spine Surgery.2025; 15(1): 38.     CrossRef
  • SPINAL DISORDER DIAGNOSIS BASED ON DEEP LEARNING INTEGRATING BIOMECHANICAL DATA
    HUI-JUAN WAN, TENG-TENG ZHANG, JIN-XIN ZHENG, BING-BING WANG, YONG-JUN CHEN
    Journal of Mechanics in Medicine and Biology.2025;[Epub]     CrossRef
  • Minimally Invasive Treatment Using Biportal Endoscopic Decompression with Vertebroplasty for Osteoporotic Vertebral Compression Fractures in Older Adult Patients
    Sang-Min Park, Sang-Soo Na, Ho-Joong Kim, Jin S. Yeom
    Clinics in Orthopedic Surgery.2025; 17(5): 836.     CrossRef
  • Interleukin Concentrations in Bone Marrow Fluid and MRI Prognostic Findings in Osteoporotic Vertebral Fractures
    Yasuhiro Nakajima, Akinori Kageyama, Yasukazu Hijikata, Ayako Motomura, Takashi Tsujiuchi, Koji Osuka
    Cureus.2025;[Epub]     CrossRef
  • Osteoporosis en columna vertebral
    Barón Zárate Kalfópulos, Irving Omar Estévez-García
    Investigación en Discapacidad.2025; 11(2): 41.     CrossRef
  • A retrospective study identifying the primary source of hidden blood loss during vertebroplasty
    Yuanhao Wang, Ting Zhao, Cong Chen, Baoshan Xu
    Medicine.2025; 104(42): e45213.     CrossRef
  • The Use of Polymethylmethacrylate Cement in Percutaneous Vertebroplasty Versus Conservative Management: How to Treat Osteoporotic Vertebral Compression Fractures
    Corrado Ciatti, Chiara Asti, Pietro Maniscalco, Michelangelo Rinaldi, Gianfranco Pirellas, Gianfilippo Caggiari, Francesco Pisanu, Angelino Sanna, Carlo Doria
    Medicina.2025; 61(11): 2004.     CrossRef
  • Influence of thoracolumbar kyphotic Cobb angle on prognosis after PKP surgery
    Peng Yuan, Xiang Ge, Qiang Shi, Yifan Wu, Zhen Yu
    Scientific Reports.2025;[Epub]     CrossRef
  • Commentary on “Deep Learning-Assisted Quantitative Measurement of Thoracolumbar Fracture Features on Lateral Radiographs”
    Chao-Hung Kuo
    Neurospine.2024; 21(1): 44.     CrossRef
  • Clinical Oversight and Delayed Diagnosis of a Pathological Compression Fracture Causing Paraplegia
    Yin-Sheng Chen, Ping-Chuan Liu, Chih-Chang Chang, Tsung-Hsi Tu, Chao-Hung Kuo
    Cureus.2024;[Epub]     CrossRef
  • Clinical significance of modified unilateral puncture percutaneous vertebroplasty guided by 3D- printed guides in the treatment of osteoporotic vertebral compression fractures: a retrospective study
    Tao Gao, Sheng-Yu Wan, Zhi-Yu Chen, Tao Li, Xu Lin, Hai-Gang Hu, Jian-Dong Tang, Chao Wu
    BMC Musculoskeletal Disorders.2024;[Epub]     CrossRef
  • Validity and reliability of the osteoporotic fracture treatment score (OF score) and outcomes across various treatments in osteoporosis vertebral compression fracture patients
    Korawish Mekariya, Borriwat Santipas, Harit Khamnurak, Wilasinee Sirichativapee, Ekkapoj Korwutthikulrangsri, Monchai Ruangchainikom, Werasak Sutipornpalangkul
    Journal of Orthopaedic Surgery and Research.2024;[Epub]     CrossRef
  • 14,887 View
  • 252 Download
  • 11 Web of Science
  • 17 Crossref

Review Article

Bone Biology and Osteoporosis Special Issue

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Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty
Neurospine. 2023;20(4):1124-1131.   Published online December 31, 2023
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Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty
Neurospine. 2023;20(4):1124-1131.   Published online December 31, 2023
Close
The management of osteoporotic vertebral fractures (OVFs) in the elderly includes nonoperative treatment and vertebroplasty, but has not been established due to the diversity of patient backgrounds. The purpose of this study was to compare the impact of 3 treatment modalities for the management of OVF: orthotic treatment, percutaneous vertebroplasty (PVP), and balloon kyphoplasty (BKP). The method was based on an analysis of the latest RCTs, meta-analyses, and systematic reviews on these topics. No study showed a benefit of bracing with high level of evidence. Trials were found that showed comparable outcomes without orthotic treatment. Only 1 randomized controlled trial (RCT) showed an improvement in pain relief up to 6 months compared with no orthosis. Rigid and nonrigid orthoses were equally effective. Four of 5 RCTs comparing vertebroplasty and sham surgery were equally effective, and one RCT showed superior pain relief with vertebroplasty within 3 weeks of onset. In open trials comparing vertebroplasty with nonoperative management, vertebroplasty was superior. PVP and BKP were comparable in terms of pain relief, improvement in quality of life, and adjacent vertebral fractures. BKP does not affect global sagittal alignment, although BKP may restore vertebral body height. An RCT was published showing that PVP was effective in chronic cases without pain relief. Vertebroplasty improved life expectancy by 22% at 10 years. The superiority of orthotic therapy for OVF was seen only in short-term pain relief. Soft orthoses proved to be a viable alternative to rigid orthoses. Vertebroplasty within 3 weeks may be useful. There is no significant difference in clinical efficacy between PVP and BKP. Vertebroplasty improves life expectancy.

Citations

Citations to this article as recorded by  Crossref logo
  • The innovative application of 3D-printed spinal braces in post-percutaneous vertebroplasty care for osteoporotic vertebral compression fractures: A retrospective study
    Ya-Ping Xiao, Jie Liu, Ling Li, Hai-Jia Xu, Wen Liao, Jia-Tao Huang, Zhang-Hua Li
    Journal of Clinical Neuroscience.2026; 143: 111723.     CrossRef
  • Multidisciplinary management of acute osteoporotic vertebral fracture: results of a national Delphi consensus
    Luis Alvarez-Galovich, Estanislao Arana, Juan Francisco Blanco Blanco, José Manuel Cancio Trujillo, Santos Castañeda, Carolina de Miguel Benadiba, Alfonso González Ramírez, Guillermo Martínez Díaz-Guerra
    Archives of Osteoporosis.2026;[Epub]     CrossRef
  • Relationship of Preexisting Vertebral Fractures and Endplate Injury to Intervertebral Bridging Ossification After Balloon Kyphoplasty for Osteoporotic Vertebral Fractures
    Toshiaki Maruyama, Naosuke Kamei, Toshio Nakamae, Yoshinori Fujimoto, Kiyotaka Yamada, Kazuto Nakao, Fadlyansyah Farid, Hiroki Fukui, Nobuo Adachi, Shashank Kaushik
    Journal of Osteoporosis.2026;[Epub]     CrossRef
  • Postoperative bracing after vertebroplasty: a prospective randomized controlled study
    Haimiti Abudouaini, Guang Yang, Jianbin Guan
    Annals of Physical and Rehabilitation Medicine.2026; 69(5): 102094.     CrossRef
  • Health-related Quality of Life After Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures
    Si Wei, Zhenjin Cai, Hao Zheng, Hongjie Zhang, Xiaoli Quan, Yaoyue Luo, Guangwei Wang
    Current Osteoporosis Reports.2026;[Epub]     CrossRef
  • Comparative Accuracy Assessment of Thoraco-Lumbo-Sacral Orthosis Fabrication: Conventional Contact Casting Versus Noncontact 3-Dimensional Digital Scanning
    Naotoshi Kumagai, Takashi Yurube, Masao Ryu, Yoshiki Takeoka, Yutaro Kanda, Kohei Kuroshima, Yoshiaki Hiranaka, Masahiko Furuya, Daisuke Nakagawa, Yu Inoue, Ryosuke Kuroda, Kenichiro Kakutani
    Neurospine.2026; 23(2): 335.     CrossRef
  • Percutaneous vertebroplasty by two-step fluoroscopy: a treatment for osteoporotic compression fractures of thoracic vertebrae in older adults
    Jianzhong Ge, Kuisheng Chen, Peng Xu, Zhiling Zhang, Kai Wang, Tao Zhang, Xin Dong, Zhigang Kang, Yizhou Ge, Feng Chang
    BMC Musculoskeletal Disorders.2025;[Epub]     CrossRef
  • Incidence of new osteoporotic adjacent vertebral body fractures. A comparison between conservative treatment and vertebral body augmentation (vertebroplasty, kyphoplasty): a systematic review and meta-analysis
    Panagiotis Korovessis, Vasileios Syrimpeis, Alkis Korovesis, Georgios Dimakopoulos
    Frontiers in Surgery.2025;[Epub]     CrossRef
  • Assessing the Role of Expandable Vertebral Augmentation versus High-Viscosity Cement Vertebroplasty in Severe Osteoporotic Vertebral Fracture Management: A Prospective Cohort Study
    Yi-Chen Liu, You-Rui Lin, Sung Huang Laurent Tsai, Ying-Chih Wang, Chia-Wei Chang, Tung-Yi Lin, Tsai-Sheng Fu, Wen-Jer Chen
    World Neurosurgery.2025; 200: 124166.     CrossRef
  • Vertebral Augmentation for Osteoporotic Vertebral Fractures
    Masahiro Kawanishi, Yutaka Ito, Hidekazu Tanaka, Naokado Ikeda, Kunio Yokoyama, Makoto Yamada, Akira Sugie, Daiji Ichihashi
    Spinal Surgery.2025; 39(3): 228.     CrossRef
  • Stem Cell and Regenerative Therapies for the Treatment of Osteoporotic Vertebral Compression Fractures
    Songzi Zhang, Yunhwan Lee, Yanting Liu, Yerin Yu, Inbo Han
    International Journal of Molecular Sciences.2024; 25(9): 4979.     CrossRef
  • Promotion of Bone Formation in a Rat Osteoporotic Vertebral Body Defect Model via Suppression of Osteoclastogenesis by Ectopic Embryonic Calvaria Derived Mesenchymal Stem Cells
    Yerin Yu, Somin Lee, Minsung Bock, Seong Bae An, Hae Eun Shin, Jong Seop Rim, Jun-oh Kwon, Kwang-Sook Park, Inbo Han
    International Journal of Molecular Sciences.2024; 25(15): 8174.     CrossRef
  • Different polymethylmethacrylate (PMMA) reinforcement strategies for long bone osteoplasty procedures: a controlled laboratory comparison using the 4-point bending test
    David Putzer, Valentina Egger, Johannes Pallua, Martin Thaler, Werner Schmölz, Michael Nogler
    BMC Musculoskeletal Disorders.2024;[Epub]     CrossRef
  • 11,019 View
  • 249 Download
  • 11 Web of Science
  • 13 Crossref

Original Articles

Bone Biology and Osteoporosis Special Issue

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Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty
Neurospine. 2023;20(4):1132-1139.   Published online December 31, 2023
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Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty
Neurospine. 2023;20(4):1132-1139.   Published online December 31, 2023
Close
Objective
The purpose of this study is to examine the utilization of kyphoplasty/vertebroplasty procedures in the management of compression fractures. With the growing elderly population and the associated increase in rates of osteoporosis, vertebral compression fractures have become a daily encounter for spine surgeons. However, there remains a lack of consensus on the optimal management of this patient population.
Methods
A retrospective analysis of 91 million longitudinally followed patients from 2016 to 2019 was performed using the PearlDiver Patient Claims Database. Patients with compression fractures were identified using International Classification of Disease, 10th Revision codes, and a subset of patients who received kyphoplasty/vertebroplasty were identified using Common Procedural Terminology codes. Baseline demographic and clinical data between groups were acquired. Multivariable regression analysis was performed to determine predictors of receiving kyphoplasty/vertebroplasty.
Results
A total of 348,457 patients with compression fractures were identified with 9.2% of patients receiving kyphoplasty/vertebroplasty as their initial treatment. Of these patients, 43.5% underwent additional kyphoplasty/vertebroplasty 30 days after initial intervention. Patients receiving kyphoplasty/vertebroplasty were significantly older (72.2 vs. 67.9, p < 0.05), female, obese, had active smoking status and had higher Elixhauser Comorbidity Index scores. Multivariable analysis demonstrated that female sex, smoking status, and obesity were the 3 strongest predictors of receiving kyphoplasty/vertebroplasty (odds ratio, 1.27, 1.24, and 1.14, respectively). The annual rate of kyphoplasty/vertebroplasty did not change significantly (range, 8%–11%).
Conclusion
The majority of vertebral compression fractures are managed nonoperatively. However, certain patient factors such as smoking status, obesity, female sex, older age, osteoporosis, and greater comorbidities are predictors of undergoing kyphoplasty/vertebroplasty.

Citations

Citations to this article as recorded by  Crossref logo
  • The Effectiveness of Fu’s Subcutaneous Needling for Residual Pain After Percutaneous Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures: A Randomized Clinical Trial Protocol
    Qiong Wang, Zhengqiang Ren, Binru Wang, Juan Du, Xinming Li, Jianjiao Mou
    Journal of Pain Research.2026; Volume 19: 1.     CrossRef
  • Minimally Invasive Treatment Using Biportal Endoscopic Decompression with Vertebroplasty for Osteoporotic Vertebral Compression Fractures in Older Adult Patients
    Sang-Min Park, Sang-Soo Na, Ho-Joong Kim, Jin S. Yeom
    Clinics in Orthopedic Surgery.2025; 17(5): 836.     CrossRef
  • Single-Level Vertebral Augmentation Procedures
    Rahul H. Jayaram, Rohil Malpani, Albert L. Rancu, Philip P. Ratnasamy, Anshu Jonnalagadda, Jonathan N. Grauer
    Clinical Spine Surgery.2025;[Epub]     CrossRef
  • Commentary on “Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty”
    Sahir S. Jabbouri, Peter G. Whang
    Neurospine.2023; 20(4): 1140.     CrossRef
  • From the Editor-in-Chief: Featured Articles in the December 2023 Issue
    Inbo Han
    Neurospine.2023; 20(4): 1093.     CrossRef
  • 10,750 View
  • 232 Download
  • 5 Web of Science
  • 5 Crossref

Bone Biology and Osteoporosis Special Issue

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The Effectiveness of Vertebral Height Restoration Based on the Vertebroplasty Procedure Used to Treat Osteoporotic Vertebral Fractures
Neurospine. 2023;20(4):1159-1165.   Published online December 31, 2023
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The Effectiveness of Vertebral Height Restoration Based on the Vertebroplasty Procedure Used to Treat Osteoporotic Vertebral Fractures
Neurospine. 2023;20(4):1159-1165.   Published online December 31, 2023
Close
Objective
Whether the use of a balloon or stent in vertebroplasty for vertebral fractures, such as balloon kyphoplasty (BKP) or vertebral body stenting (VBS), actually contributes to the restoration of postoperative vertebral height is unclear. The aim of the current study was to compare the effectiveness of percutaneous vertebroplasty (PVP), BKP, and VBS in the correction of collapsed vertebrae in patients with painful vertebral fractures.
Methods
The cases studied involved 34 vertebrae in 28 patients treated with PVP, 43 vertebrae in 38 patients treated with BKP, and 20 vertebrae in 20 patients treated with VBS at Izinkai Takeda General Hospital. Changes in the vertebral height and local kyphosis angle were measured based on standing lumbar radiographs before and after surgery and were compared among the treatment groups.
Results
There were no differences in changes in the height of the anterior wall, middle body, or posterior wall of the treated vertebrae among the 3 treatment groups. The same was true for changes in the local kyphosis angle. The effectiveness of vertebral height restoration depended heavily upon preoperative vertebral instability in all the treatment groups. Correction loss due to balloon deflation effect or balloon sinking was noted with VBS or BKP.
Conclusion
BKP and VBS have the advantage of reducing the risk of extravertebral leakage of injected bone cement, but they have a disadvantage in that they are no more effective than PVP in restoring collapsed vertebrae despite the use of a balloon or metal stent.

Citations

Citations to this article as recorded by  Crossref logo
  • Clinical Outcomes of Vertebral Body Stenting for Osteoporotic Vertebral Fractures: Focus on Collapse Prevention and Magnetic Resonance Imaging-Based Indication
    Kenji Uda, Takayuki Awaya, Toshiki Fukuoka, Tomotaka Iwakoshi, Hinako Nagamatsu, Kazuki Ishii, Takashi Abe, Osamu Suzuki, Yoshitaka Nagashima, Takafumi Tanei, Yusuke Nishimura, Ryuta Saito
    Global Spine Journal.2026; 16(2): 992.     CrossRef
  • Comparison of Surgical Outcomes Between Vertebral Body Stenting (VBS) and Balloon Kyphoplasty (BKP)—Multicenter Cohort Study
    Akiyoshi Miyamoto, Ingrid Ignacio, Masato Tanaka, Shinya Arataki, Tadashi Komatsubara, Ryo Ugawa, Nitin Jaiswal, Pankaj Kumar Sharma, Yoshiaki Oda, Koji Uotani
    Journal of Clinical Medicine.2026; 15(9): 3371.     CrossRef
  • Minimally Invasive Treatment Using Biportal Endoscopic Decompression with Vertebroplasty for Osteoporotic Vertebral Compression Fractures in Older Adult Patients
    Sang-Min Park, Sang-Soo Na, Ho-Joong Kim, Jin S. Yeom
    Clinics in Orthopedic Surgery.2025; 17(5): 836.     CrossRef
  • Comparative Radiologic and Morphologic Analysis of Posterolateral Fusion and Percutaneous Pedicle Screw Fixation for Thoracolumbar Junction Burst Fractures
    Hyung-Rae Lee, Minseung Kang, Jae Min Park, Jae-Hyuk Yang
    Journal of Clinical Medicine.2025; 14(18): 6379.     CrossRef
  • Stem Cell and Regenerative Therapies for the Treatment of Osteoporotic Vertebral Compression Fractures
    Songzi Zhang, Yunhwan Lee, Yanting Liu, Yerin Yu, Inbo Han
    International Journal of Molecular Sciences.2024; 25(9): 4979.     CrossRef
  • Promotion of Bone Formation in a Rat Osteoporotic Vertebral Body Defect Model via Suppression of Osteoclastogenesis by Ectopic Embryonic Calvaria Derived Mesenchymal Stem Cells
    Yerin Yu, Somin Lee, Minsung Bock, Seong Bae An, Hae Eun Shin, Jong Seop Rim, Jun-oh Kwon, Kwang-Sook Park, Inbo Han
    International Journal of Molecular Sciences.2024; 25(15): 8174.     CrossRef
  • 5,730 View
  • 224 Download
  • 6 Web of Science
  • 6 Crossref

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Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Neurospine. 2021;18(1):226-233.   Published online March 31, 2021
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Cement Augmentation of Vertebral Compression Fractures May Be Safely Considered in the Very Elderly
Neurospine. 2021;18(1):226-233.   Published online March 31, 2021
Close
Objective
The objective of the current study was to perform a retrospective review of a national database to assess the safety of cement augmentation for vertebral compression fractures in geriatric populations in varying age categories.
Methods
The 2005–2016 National Surgical Quality Improvement Program databases were queried to identify patients undergoing kyphoplasty or vertebroplasty in the following age categories: 60–69, 70–79, 80–89, and 90+ years old. Demographic variables, comorbidity status, procedure type, provider specialty, inpatient/outpatient status, number of procedure levels, and periprocedure complications were compared between age categories using chi-square analysis. Multivariate logistic regressions controlling for patient and procedural variables were then performed to assess the relative periprocedure risks of adverse outcomes of patients in the different age categories relative to those who were 60–69 years old.
Results
For the 60–69, 70–79, 80–89, and 90+ years old cohorts, 486, 822, 937, and 215 patients were identified, respectively. After controlling for patient and procedural variables, 30-day any adverse events, serious adverse events, reoperation, readmission, and mortality were not different for the respective age categories. Cases in the 80- to 89-year-old cohort were at increased risk of minor adverse events compared to cases in the 60- to 69-year-old cohort.
Conclusion
As the population ages, cement augmentation is being considered as a treatment for vertebral compression fractures in increasingly older patients. These results suggest that even the very elderly may be appropriately considered for these procedures (level of evidence: 3).

Citations

Citations to this article as recorded by  Crossref logo
  • Surgical management of spinal metastases from primary lung carcinoma: demographics, clinical characteristics, and outcomes—A retrospective analysis
    Jun Li, Yuhan Zheng, Xiaohua Lv, Rong Zeng, Yating Zhao, Yucheng Xiang, Ke Zhan, Congcong Liu, Houqing Long, Ke Chen
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Advantages of TiRobot-assisted surgery in the treatment of osteoporotic thoracolumbar compression fractures: a meta-analysis based on multiple clinical indicators
    Yu Liu, Zidong Xia, Huiling Chen, Jian Wang, Mengtian Cao, Guohang Shen, Mingyuan Fan, Kaiyong Wang, Yang Chen, Yupei Dai
    Journal of Robotic Surgery.2025;[Epub]     CrossRef
  • Spinal augmentation for vertebral body fractures in the elderly population
    Alexander R. Evans, Taylor Niznik, Chao Li, Zachary A. Smith
    GeroScience.2025;[Epub]     CrossRef
  • The future of ambulatory surgery for geriatric patients
    Mary Ann Vann
    Best Practice & Research Clinical Anaesthesiology.2023; 37(3): 343.     CrossRef
  • What are the risk factors for a second osteoporotic vertebral compression fracture?
    Sang Hoon Hwang, Pyung Goo Cho, Kyoung-Tae Kim, Keung Nyun Kim, Sang Hyun Kim, Sung Hyun Noh
    The Spine Journal.2023; 23(11): 1586.     CrossRef
  • Beyond Pain Relief: An In-Depth Review of Vertebral Height Restoration After Balloon Kyphoplasty in Vertebral Compression Fractures
    Siddharth K Patel, Sohael Khan, Ventaktesh Dasari, Suvarn Gupta
    Cureus.2023;[Epub]     CrossRef
  • Risk of Revision After Vertebral Augmentation for Osteoporotic Vertebral Fracture: A Narrative Review
    Shinji Takahashi, Hiroyuki Inose, Koji Tamai, Masayoshi Iwamae, Hidetomi Terai, Hiroaki Nakamura
    Neurospine.2023; 20(3): 852.     CrossRef
  • The Effectiveness of Vertebral Height Restoration Based on the Vertebroplasty Procedure Used to Treat Osteoporotic Vertebral Fractures
    Kunio Yokoyama, Naokado Ikeda, Hidekazu Tanaka, Yutaka Ito, Akira Sugie, Makoto Yamada, Masahiko Wanibuchi, Masahiro Kawanishi
    Neurospine.2023; 20(4): 1159.     CrossRef
  • Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty
    Masahiro Kawanishi, Hidekazu Tanaka, Yutaka Ito, Makoto Yamada, Kunio Yokoyama, Akira Sugie, Naokado Ikeda
    Neurospine.2023; 20(4): 1124.     CrossRef
  • Commentary on “Utilization of Vertebroplasty/Kyphoplasty in the Management of Compression Fractures: National Trends and Predictors of Vertebroplasty/Kyphoplasty”
    Sahir S. Jabbouri, Peter G. Whang
    Neurospine.2023; 20(4): 1140.     CrossRef
  • Difference in the Cobb Angle Between Standing and Supine Position as a Prognostic Factor After Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures
    In-Suk Bae, Byung Gwan Moon, Hee In Kang, Jae Hoon Kim, Cheolsu Jwa, Deok Ryeong Kim
    Neurospine.2022; 19(2): 357.     CrossRef
  • Kyphoplasty: why, when and how?
    Umile Giuseppe Longo, Rocco Papalia, Sergio De Salvatore, Valentina Piccioni, Vincenzo Denaro
    International Journal of Bone Fragility.2022; 2(1): 41.     CrossRef
  • 10,505 View
  • 221 Download
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Clinical Articles

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Balloon Kyphoplasty: An Effective Treatment for Kummell Disease?
Korean J Spine. 2016;13(3):102-106.   Published online September 30, 2016
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Balloon Kyphoplasty: An Effective Treatment for Kummell Disease?
Korean J Spine. 2016;13(3):102-106.   Published online September 30, 2016
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Objective

The purpose of this study was to evaluate the efficacy of balloon kyphoplasty for treating Kummel disease accompanying severe osteoporosis.

Methods

Twelve patients with single-level Kummell disease accompanied by severe osteoporosis were enrolled in this investigation. After postural reduction for 1 or 2 days, balloon kyphoplasty was performed on the collapsed vertebrae. Clinical results, radiological parameters, and related complications were assessed at 7 days, 1 month and 6 months after the procedure.

Results

Prior to kyphoplasty, the mean pain score (according to the visual analogue scale) was 8.0. Seven days after the procedure, this score improved to 2.5. Despite the significant improvement compared to preoperative value, the score increased to 4.0 at 6 months after the procedure. The mean preoperative vertebral height loss was 55.4%. Kyphoplasty reduced this loss to 31.6%, but it increased to 38.7% at 6 months after the procedure. The kyphotic angle improved significantly from 22.4°±4.9° (before the procedure) to 10.1°±3.8° after surgery, However, the improved angle was not maintained 6 months after the procedure. The mean correction loss for the kyphotic deformity was 7.2° at 6 months after the procedure. Three out of 12 patients sustained adjacent fractures after balloon kyphoplasty within 6 months.

Conclusion

Although balloon kyphoplasty for treating Kummell disease is known to provide stabilization and pain relief, it may be associated with the development of adjacent fractures and aggravated kyphosis.

Citations

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  • Unilateral percutaneous kyphoplasty in Kümmell’s disease: a clinical efficacy evaluation
    Dongdong Shi, Xiaoling Li, Zhoudan Lin, Gejin Wei
    Interdisciplinary Neurosurgery.2026; 43: 102239.     CrossRef
  • Semi-vertebral column resection with preservation of posterior ligament complex for Kümmell’s disease: a case report
    Tong-Hao Wang, Zhi Liu, Yong-Gang Tian, Guo-Yue Yang, Li-Qiang Han
    Journal of Medical Case Reports.2025;[Epub]     CrossRef
  • A Narrative Review for Mechanisms and Management of Secondary Vertebral Collapse Following Minimally Invasive Bone Cement Augmentation Procedures for Osteoporotic Vertebral Compression Fractures
    Bing-Yi Yang, Shao-Kuan Song, Huo-Liang Zheng, Qi-Zhu Chen, Hao Cai, Yong Wang, Muradil Mardan, Lei-Sheng Jiang, Sheng-Dan Jiang
    Journal of Investigative Surgery.2025;[Epub]     CrossRef
  • A Comparative Study of 2 Techniques to Avoid Bone Cement Loosening and Displacement After Percutaneous Vertebroplasty Treating Unstable Kummell Disease
    Jie Guo, Yesheng Bai, Liang Li, Jiangtao Wang, Yuhang Wang, Dinghun Hao, Biao Wang
    Neurospine.2024; 21(2): 575.     CrossRef
  • Hollow Screw Placement Combined with Percutaneous Vertebroplasty Serves as a Valuable Three-Column Intensive Treatment for Patients with Kummell’s Disease and Pedicle Rupture
    Yapu Liu, Yuanyuan Su, Zhonghao Luan, Xiuwei Hou, Guangliang Wu, Yonghui Xu, Songmao Wang, Lifeng Gao, Xiaochen Zheng
    Journal of Pain Research.2024; Volume 17: 2767.     CrossRef
  • A comparative study of PSPVP and PSIBG in the treatment of stage II–III Kummell’s disease
    Jian-Qiao Zhang, Zhong-You Zeng, Hui-Gen Lu, Wei Yu, Xu-Qi Hu, Wei-Shan Chen, Gang Chen
    Bio-Medical Materials and Engineering.2023; 34(3): 261.     CrossRef
  • Evaluation of the clinical efficacy of the bilateral pedicle cement anchoring technique in percutaneous vertebroplasty for Kümmell disease
    Dexin Zou, Huimin Wang, Yong Zhao, Xuri Sun, Wei Du
    Experimental and Therapeutic Medicine.2023;[Epub]     CrossRef
  • Acute Paraparesis Caused by Spinal Epidural Fluid After Balloon Kyphoplasty for Traumatic Avascular Necrosis: A Case Report
    Chi Ho Kim, Pius Kim, Chang Il Ju, Seok Won Kim
    Korean Journal of Neurotrauma.2023; 19(3): 398.     CrossRef
  • Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty
    Masahiro Kawanishi, Hidekazu Tanaka, Yutaka Ito, Makoto Yamada, Kunio Yokoyama, Akira Sugie, Naokado Ikeda
    Neurospine.2023; 20(4): 1124.     CrossRef
  • Comparison between Percutaneous Kyphoplasty and Posterior Fixation Combined with Vertebroplasty in the Treatment of Stage III Kümmell’s Disease without Neurological Deficit
    Yijie Liu, Yi Zhu, Renjie Li, Weimin Jiang, Huilin Yang, Ajoy Prasad Shetty
    BioMed Research International.2022;[Epub]     CrossRef
  • The Use of Three-Column Enhanced Percutaneous Vertebroplasty to Treat Kummell’s Disease
    Yapu Liu, Yuanyuan Su, Yonghui Xu, Songmao Wang, Lifeng Gao, Xiaochen Zheng, Hailong Ge
    Journal of Pain Research.2022; Volume 15: 2919.     CrossRef
  • Vertebral Collapse Prevented Following Teriparatide Treatment in Postmenopausal Kümmell's Disease Patients with Severe Osteoporosis
    Peng‐guo Gou, Zhi‐hui Zhao, Jia‐ming Zhou, Lin‐hui Ren, Xiao‐yun Wang, Yu‐feng Mu, Yun‐guo Wang, Feng Chang, Yuan Xue
    Orthopaedic Surgery.2021; 13(2): 506.     CrossRef
  • Percutaneous vertebroplasty versus kyphoplasty for the treatment of neurologically intact osteoporotic Kümmell’s disease
    Shou-qian Dai, Rong-qing Qin, Xiu Shi, Hui-lin Yang
    BMC Surgery.2021;[Epub]     CrossRef
  • Modified poly(methyl methacrylate) bone cement in the treatment of Kümmell disease
    Jinjin Zhu, Shuhui Yang, Yute Yang, Teng Yao, Gang Liu, Shunwu Fan, He Zhao, Fuzhai Cui, Xiumei Wang, Guoqiang Jiang, Xiangqian Fang
    Regenerative Biomaterials.2021;[Epub]     CrossRef
  • Impending cauda equina syndrome due to Kummell disease; A case report and literature review
    Farzad Omidi-Kashani, Ali Parsa, Daniel Madarshahian
    International Journal of Surgery Case Reports.2021; 83: 106041.     CrossRef
  • Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
    Guo-ye Mo, Teng-peng Zhou, Hui-zhi Guo, Yong-xian Li, Yong-chao Tang, Dan-qing Guo, Pei-jie Luo, Dong-xiao Li, Kai Yuan, Ling Mo, Shun-cong Zhang
    Scientific Reports.2021;[Epub]     CrossRef
  • Radiographic and clinical outcomes of surgical treatment of Kümmell’s disease with thoracolumbar kyphosis: a minimal two-year follow-up
    Hao Cheng, Guo-dong Wang, Tao Li, Xiao-yang Liu, Jian-min Sun
    BMC Musculoskeletal Disorders.2021;[Epub]     CrossRef
  • Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study
    Jian-Zhong Chang, Ming-Jian Bei, Dong-Ping Shu, Cheng-Jun Sun, Ji-Bin Chen, Ya-Ping Xiao
    BMC Musculoskeletal Disorders.2020;[Epub]     CrossRef
  • Analysis of two minimally invasive procedures for osteoporotic vertebral compression fractures with intravertebral cleft: a systematic review and meta-analysis
    Hongyu Wei, Chunke Dong, Yuting Zhu, Haoning Ma
    Journal of Orthopaedic Surgery and Research.2020;[Epub]     CrossRef
  • Transforaminal Interbody Impaction of Bone Graft to Treat Collapsed Nonhealed Vertebral Fractures with Endplate Destruction: A Report of Two Cases
    Adam M. Wegner, Yu-Hsuan Chou, Hsiao-Kang Chang, Tsung-Cheng Yin
    Case Reports in Orthopedics.2020; 2020: 1.     CrossRef
  • The Treatment Evaluation for Osteoporotic Kummell Disease by Modified Posterior Vertebral Column Resection: Minimum of One-Year Follow-Up
    Da-Long Yang, Si-Dong Yang, Qian Chen, Yong Shen, Wen-Yuan Ding
    Medical Science Monitor.2017; 23: 606.     CrossRef
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Comparative Clinical Results of Vertebroplasty Using Jamshidi® Needle and Bone Void Filler for Acute Vertebral Compression Fractures
Korean J Spine. 2012;9(3):239-243.   Published online September 30, 2012
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Comparative Clinical Results of Vertebroplasty Using Jamshidi® Needle and Bone Void Filler for Acute Vertebral Compression Fractures
Korean J Spine. 2012;9(3):239-243.   Published online September 30, 2012
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Objective

Percutaneous vertebroplasty (PVP) is an effective treatment modality for management of osteoporotic compression fracture. However physicians sometimes have problems of high pressure in cement delivery and cement leakage when using Jamshidi® needle (JN). Bone void filler (BVF) has larger lumen which may possibly diminish these problems. This study aims to compare the radiologic and clinical outcome of JN and BVF for PVP.

Methods

One hundred twenty-eight patients were treated with PVP for osteoporotic vertebral compression fracture (VCF) where 46 patients underwent PVP with JN needle and 82 patients with BVF. Radiologic outcome such as kyphotic angle and vertebral body height (VBH) and clinical outcome such as visual analog scale (VAS) scores were measured after treatment in both groups.

Results

In JN PVP group, mean of 3.26 cc of polymethylmethacrylate (PMMA) were injected and 4.07 cc in BVF PVP group (p<0.001). For radiologic outcome, no significant difference in kyphotic angle reduction was observed between two groups. Cement leakage developed in 6 patients using JN PVP group and 2 patients using BVF group (p=0.025). No significant difference in improvement of VAS score was observed between JN and BVF PVP groups (p=0.43).

Conclusion

For the treatment of osteoporotic VCF, usage of BVF for PVP may increase injected volume of cement, easily control the depth and direction of PMMA which may reduce cement leakage. However, improvement of VAS score did not show difference between two groups. Usage of BVF for PVP may be an alternative to JN PVP in selected cases.

Citations

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  • Percutaneous Vertebral Body Augmentations
    Majid Khan, Sergiy V. Kushchayev
    Neuroimaging Clinics of North America.2019; 29(4): 495.     CrossRef
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  • 71 Download
  • 1 Crossref

Case Report

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Late Onset Tuberculous Spondylitis Following Kyphoplasty: A Case Report and Review of the Literature
Korean J Spine. 2012;9(1):28-31.   Published online March 31, 2012
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Late Onset Tuberculous Spondylitis Following Kyphoplasty: A Case Report and Review of the Literature
Korean J Spine. 2012;9(1):28-31.   Published online March 31, 2012
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A 76-year-old woman with compression fracture of L1 underwent percutaneous balloon kyphoplasty using polymethyl methacrylate. Three years after kyphoplasty of L1, the patient was readmitted with severe low back pain. Magnetic resonance imaging revealed progressive collapse of L1 vertebra and new compression fracture at T12. There were no signs of infection. As conservative treatment failed, combined surgery consisting of anterior corpectomy of T12 and L1, interposition of a titanium mesh cage filled with autologous rib graft, and anterior instrumentation of T11-L2 was performed. Histologic examination showed granulomatous inflammation surrounding the cement. Polymerase chain reaction and culture of the specimen confirmed the diagnosis of tuberculosis. The anti-tuberculous medications were administered for 10 months, and the patient recovered without any sequelae. Tuberculous spondylitis should be included in the differential diagnosis of spondylitis after cement augmentation. If conservative antibiotic therapy fails, resection of the infected bone-cement complex is indicated.

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  • Tuberculous Spondylitis and Paravertebral Abscess Formation Following Vertebroplasty: A Case Report and Review of the Literature
    Wensen Pi, Yang Liu, Haidan Chen, Hongwei Zhao
    Infection and Drug Resistance.2024; Volume 17: 5171.     CrossRef
  • Late-onset spondylodiscitis and psoas abscess, 5 years after percutaneous balloon kyphoplasty: a case report
    Kalliopi Alpantaki, Christos Koutserimpas, Diamantis P Kofteridis, Sotirios Papastefanou, George Samonis
    British Journal of Neurosurgery.2023; 37(4): 615.     CrossRef
  • Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study
    Bo-Wen Zheng, Fu-Sheng Liu, Bo-Yv Zheng, Hua-Qing Niu, Jing Li, Guo-Hua Lv, Ming-Xiang Zou, Zhun Xu
    Frontiers in Surgery.2022;[Epub]     CrossRef
  • Debridement and corpectomy via single posterior approach to treat pyogenic spondylitis after vertebral augmentation
    Shuai Zhang, Song Wang, Qing Wang, Jin Yang, Shuang Xu
    BMC Musculoskeletal Disorders.2021;[Epub]     CrossRef
  • Tuberculous spondylitis after percutaneous vertebroplasty: A case series of 9 cases
    Po-Ju Lai, Jen-Chung Liao, Lih-Hui Chen, Po-Liang Lai
    Biomedical Journal.2019; 42(4): 285.     CrossRef
  • Tuberculous spondylitis after vertebral augmentation: A case report with a literature review
    Sun Jia-Jia, Sun Zhi-Yong, Qian Zhong-Lai, Yang Hui-Lin, Zhu Xiao-Yu
    Journal of International Medical Research.2018; 46(2): 916.     CrossRef
  • Infection following percutaneous vertebral augmentation with polymethylmethacrylate
    Jae-Woo Park, Sang-Min Park, Hui Jong Lee, Choon-Ki Lee, Bong-Soon Chang, Hyoungmin Kim
    Archives of Osteoporosis.2018;[Epub]     CrossRef
  • Surgical outcomes of infectious spondylitis after vertebroplasty, and comparisons between pyogenic and tuberculosis
    Jen-Chung Liao, Po-Liang Lai, Lih-Hui Chen, Chi-Chien Niu
    BMC Infectious Diseases.2018;[Epub]     CrossRef
  • Vertebral Localization of Multifocal Skeletal Tuberculosis: Case Report and Literature Review
    Fulbert Kouakou, Alban Slim Mbende, André Tokpa, Nicole Adou, Dominique N’Dri Oka
    Open Journal of Modern Neurosurgery.2017; 07(02): 11.     CrossRef
  • Tuberculous Spondylitis Following Kyphoplasty
    Chao-Yuan Ge, Li-Ming He, Yong-Hong Zheng, Tuan-Jiang Liu, Hua Guo, Bao-Rong He, Li-Xiong Qian, Yuan-Tin Zhao, Jun-Song Yang, Ding-Jun Hao
    Medicine.2016; 95(11): e2940.     CrossRef
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Original Articles

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Therapeutic Effects and Prognostic Factors of Kyphoplasty for Thoracolumbar Osteoporotic Burst Fracture Patients.
Korean J Spine. 2011;8(3):172-177.
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Therapeutic Effects and Prognostic Factors of Kyphoplasty for Thoracolumbar Osteoporotic Burst Fracture Patients.
Korean J Spine. 2011;8(3):172-177.
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OBJECTIVE
There are few studies of osteoporotic burst fractures with spinal canal compromise that were treated with kyphoplasty. The purpose of this study was to assess the efficacy and the safety of kyphoplasty for the treatment of thoracolumbar spine osteoporotic burst fractures without neurological deficits and to investigate predictors that can improve the effectiveness of this treatment.
METHODS
From October 2004 until December 2010, 79 osteoporotic burst fracture patients with asymptomatic spinal canal compromise were treated by kyphoplasty. Kyphoplasty involved injecting polymethylmethacrylate (PMMA) from the anterior one-third of the vertebral body into the posterior one-third of the vertebral body. PMMA powder and liquid were mixed in a ratio of 1:3 at 21-23degrees C. Preoperative and postoperative visual analog scores (VAS), kyphotic angles, the heights of the vertebral body, and the degrees of spinal canal compromise were analyzed. The relationships between the factors and the VAS difference between the preoperative and postoperative states were analyzed.
RESULTS
The mean postoperative VAS, the postoperative kyphotic angle, the vertebral body height measurement from the anterior and the middle of the body were significantly improved after kyphoplasty (p<0.05). Postoperatively, the mean VAS was restored from 7.35 to 2.11, the postoperative kyphotic angle was restored from 18.21degrees to 12.08degrees, the vertebral body height measurement from the anterior of the body was from 18.56mm to 23.54mm and the middle of the body was from 24.81mm to 27.90mm. Among the variables, only the duration of symptoms before surgical treatment was implicated as a factor in the outcome (p<0.01).
CONCLUSION
Kyphoplasty is a very effective and safe therapeutic modality for the treatment of osteoporotic burst fractures without neurological deficits. The standardization of this procedure helps to avoid complications. In the acute stages, early treatment is more effective for the reduction of pain. Further investigation is warranted in order to assess the effectiveness of early surgery in improving outcome.
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The Comparative Study for Clinical and Radiologic Results of Unilateral Kyphoplasty and Bilateral Vertebroplasty.
Korean J Spine. 2010;7(4):242-248.
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The Comparative Study for Clinical and Radiologic Results of Unilateral Kyphoplasty and Bilateral Vertebroplasty.
Korean J Spine. 2010;7(4):242-248.
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OBJECTIVE
To elucidate postoperative clinical and radiologic efficacy of unilateral kyphoplasty compared for percutaneous bilateral vertebroplasty.
METHODS
One hundred patients with osteoporotic compression fracture at thoracolumbar junction were enrolled in this study. The kyphotic angle and reduction rate were measured to evaluate the vertebral restoration. Visual analog scale (VAS) for pain and short form-36 (SF-36) and Oswestry Disability Index (ODI) for functional outcome were recorded by 1 year postoperatively. Cement extravasation and adjacent vertebral fractures were monitored.
RESULTS
Visual analog scale for pain was not statistically different through the follow up in both groups (p=0.38). The preoperative SF-36 and ODI scores were similar (p>0.05) but the difference in ODI score and standardized physical component scale reached statistical significance (p=0.04, p=0.03) and unilateral kyphoplasty group was getting better functional status. Reduction rate of vertebral body was 42.5+/-7.8% for the vertebroplasty group and 66.3+/-8.1% for the unilateral kyphoplasty group (p<0.001) and loss of reduction was 4.5+/-3.5% and 1.7+/-2.5% (p<0.0001) respectively. There were six complications of cement extraosseous leakage into the spinal canal in vertebroplasty only.
CONCLUSION
Unilateral kyphoplasty in compare with vertebroplasty is safer for cement leakage and immediately reduces back pain and restore kyphotic deformities in addition to the prevention of subsequent compression fracture.
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The Clinical Evaluation of Calcium Phosphate Cement Compared with Polymethylmethacrylate for Kyphoplasty.
Korean J Spine. 2008;5(3):167-172.
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The Clinical Evaluation of Calcium Phosphate Cement Compared with Polymethylmethacrylate for Kyphoplasty.
Korean J Spine. 2008;5(3):167-172.
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OBJECTIVE
We investigated the clinical outcome of kyphoplasty using calcium phosphate (CaP) for vertebral augmentation compared with polymethylmethacrylate (PMMA). We conducted a retrospective study to determine whether patients with osteoporotic vertebral fracture who underwent CaP kyphoplasty had improved outcome in the correction of vertebral body and relief of pain compared with those who underwent PMMA treatment.
METHODS
From January 2005 to December 2006, 117 consecutive patients with osteoporotic compression fracture were treated at our institute. Among them, 23 patients have treated to kyphoplasty using PMMA or CaP. We reviewed the clinical data and imaging studies retrospectively as sources for analysis.
RESULTS
The 23 patients included in the study. A mean ages of CaP and PMMA group were 70+/-9.5 and 67+/-9.5 years respectively. Preoperative compression ratios (CR) were 0.71+/-0.12 and 0.74+/-0.15 on both groups. Postoperative CR, however, showed the difference between two groups. The differences of preoperative and postoperative Cobb`s angle were 10.04 and 2.18 on CaP and PMMA group respectively and the mean injected volume of cement were 3.85+/-1.73 and 4.4+/-1.23 ml.
CONCLUSION
The amount of injected volume of bone cement in kyphoplasty has no difference on both groups. But, follow-up compression ratio and Cobb`s angle are larger in CaP group than PMMA group. However, pain and functional recovery is not different on both group. As a result, CaP can not sufficiently support the strength of vertebral body, but be used to control the acute pain.
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Comparison Vertebroplasty with Kyphoplasty in Delayed Post-traumatic Osteonecrosis of a Vertebral Body(Kummell's Disease).
Korean J Spine. 2008;5(2):70-76.
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Comparison Vertebroplasty with Kyphoplasty in Delayed Post-traumatic Osteonecrosis of a Vertebral Body(Kummell's Disease).
Korean J Spine. 2008;5(2):70-76.
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OBJECTIVE
Kummell's disease is a rare spinal disorder with delayed post-traumatic osteonecrosis of a vertebral body and the pathophysiology is still unclear. Percutaneous vertebroplasty was found to be an effective procedure as a treatment, but there are not sufficient studies. We evaluated the efficacy and complications of vertebroplasty or kyphoplasty in the treatment of delayed post-traumatic intravertebral osteonecrosis.
METHODS
A retrospective review was conducted of 29 patients complicated with delayed post-traumatic intravertebral osteonecrosis among the 393 cases of osteoporotic vertebral compression fracture treated with vertebroplasty or kyphoplasty from January 2001 to June 2005. With 29 cases of intravertebral osteonecrosis, we reviewed the duration from initiation of symptoms to admission and the history of trauma. Also, we analysed the restoration of height of vertebral body, the correction of kyphotic angle, the clinical results with VAS score, the amount of injected polymethylmethacrylate(PMMA), and the complications due to PMMA leakage between the vertebroplasty and kyphoplasty.
RESULTS
There were 29 patients(22 females and 7 males) complicated with delayed post-traumatic osteonecrosis of vertebral body(7.3%), and mean age was 73.3 years. The cases with prominent traumatic history were 19 and the mean duration from initiation of symptoms to admission was 5.9 weeks. The whole surgically treated levels were 31 levels; 19 levels with vertebroplasty(group A), 12 levels with kyphoplasty(group B). The leakage of PMMA was occurred in 9 levels; 6 levels in vertebroplasty and 3 levels in kyphoplasy. However, there were no serious complications. In the VAS score, there was 4.9 in group A compared to 5.3 in group B. But there was no significant difference statistically. We measured vertebral body height and kyphotic angle to figure out the degree of restoration after procedures. Both group A and B showed somewhat effective restoration of vertebral height and correction of kyphotic angle. However, there were no stastical differences between two groups. After 14 months, restored vertebral heights and corrected kyphotic angles reaggravated and this suggest that the process of vertebral osteonecrosis is going on even after receiving vertebroplasty and kyphoplasty.
CONCLUSION
For the treatment of Kummell's disease, both vertebroplasty and kyphoplasty seemed to be somewhat effective. Although the PMMA leakage occurred more often in vertebroplasty group than kyphoplasty group, there were no statiscal difference in recovery of VAS score. However, the process of intravertebral osteonecrosis can be developed continuously after procedure which may be the cause of serious complications. Therefore, continuous follow-up observation after procedure should be recommended.
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Case Report

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Is Kummell's Disease a Independent Disease Entity?: Two Case Report.
Korean J Spine. 2008;5(1):24-28.
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Is Kummell's Disease a Independent Disease Entity?: Two Case Report.
Korean J Spine. 2008;5(1):24-28.
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The authors report 2 patients with benign vertebral compression fracture with intravertebral vacuum. Both patients suffered from back pain after minor back trauma and were treated by kyphoplasty. The spine images of one case shows intra-and inter-vertebral vacuum dots since 1weeks after trauma. The other's shows only intravertebral vacuum dots immediately after trauma and then intravertebral vacuum cleft(Kummell's disease) 5 weeks after trauma. The authors speculate that Kummell's disease(delayed posttraumatic vertebral collapse with intravertebral vacuum cleft) was evolved from untreated or unrecognized vertebral compression fracture. Kummell's disease is not a independent disease entity.
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