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Optimal Positioning for Single-Position Lateral Lumbar Interbody Fusion
Neurospine. 2026;23(1):216-225.   Published online January 31, 2026
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Optimal Positioning for Single-Position Lateral Lumbar Interbody Fusion
Neurospine. 2026;23(1):216-225.   Published online January 31, 2026
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Objective
To quantify the effect of different hip positions on lumbar lordosis (LL) and spinopelvic parameters in the right lateral decubitus position (RLDP) and identify the configuration that most closely replicates physiologic standing alignment during lateral lumbar interbody fusion in minimally invasive spinal surgery.
Methods
Thirty healthy volunteers (15 males, 15 females; mean age, 27.8±8.6 years) underwent lateral lumbar radiographs in standing position and 5 RLDP configurations: neutral hips (NN), 30° flexion of both hips (30FF), 30° flexion of the right hip with left hip neutral (30FN), 60° flexion of both hips (60FF), and 60° flexion of the right hip with left hip neutral (60FN). LL, pelvic tilt (PT), sacral slope (SS), and pelvic incidence (PI) were measured. Each position was compared to standing using paired t-tests. Intra- and interobserver reliability were evaluated using intraclass correlation coefficients (ICCs).
Results
LL decreased significantly in all RLDP positions compared with standing (51.1°±3.8°). The 30FN position showed the smallest change (ΔLL=-4.9°, p<0.001), whereas 60FF showed the greatest (ΔLL=-15.0°, p<0.001). In 30FN, PT decreased (p=0.013) and SS increased (p=0.003), indicating mild anterior pelvic rotation. PI showed minimal variation across positions. Intra- and interobserver ICCs ranged from 0.92 to 0.99, confirming high measurement reliability.
Conclusion
Hip position significantly influences lumbar and pelvic alignment in RLDP. Among tested configurations, the 30FN position (right hip flexed 30°, left neutral) showed the smallest numerical deviation from standing alignment and spinopelvic harmony relative to standing in RLDP.

Citations

Citations to this article as recorded by  Crossref logo
  • Reply Letter: Reconsidering Intraoperative Hip Positioning in Single-Position Lateral Lumbar Interbody Fusion – A Commentary on “Optimal Positioning for Single-Position Lateral Lumbar Interbody Fusion”
    Worawat Limthongkul, Natavut Prasertkul, Pakawas Praisarnti, Maruay Tanayavong, Surachat Jaroenwareekul, Wicharn Yingsakmongkol, Weerasak Singhatanadgige, Vit Kotheeranurak
    Neurospine.2026; 23(3): 756.     CrossRef
  • Reconsidering Intraoperative Hip Positioning in Single-Position Lateral Lumbar Interbody Fusion – A Commentary on “Optimal Positioning for Single-Position Lateral Lumbar Interbody Fusion”
    Jiayi Chen
    Neurospine.2026; 23(3): 754.     CrossRef
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  • 2 Crossref

Spinal Deformity

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Proximal Junctional Failure Development Despite Achieving Ideal Sagittal Correction According to Age-Adjusted Alignment Target in Patients With Adult Spinal Deformity: Risk Factor Analysis of 196 Cases Undergoing Low Thoracic to Pelvic Fusion
Neurospine. 2024;21(4):1080-1090.   Published online December 31, 2024
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Proximal Junctional Failure Development Despite Achieving Ideal Sagittal Correction According to Age-Adjusted Alignment Target in Patients With Adult Spinal Deformity: Risk Factor Analysis of 196 Cases Undergoing Low Thoracic to Pelvic Fusion
Neurospine. 2024;21(4):1080-1090.   Published online December 31, 2024
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Objective
To identify the risk factors for proximal junctional failure (PJF) after adult spinal deformity (ASD) surgery despite ideal sagittal correction according to age-adjusted alignment target.
Methods
The study included patients who underwent low thoracic to pelvic fusion for ASD and obtained ideal correction according to age-adjusted pelvic incidence minus lumbar lordosis. PJF was defined either radiographically as a proximal junctional angle (PJA) of >28° plus a difference in PJA of >22° or clinically as revision surgery for proximal junctional complications. Clinical and radiographic variables were assessed to identify the risk factors for PJF.
Results
The final study cohort consisted of 196 patients, of whom 170 were women (86.7%), with an average age of 68.3 years. During mean follow-up duration of 45.9 months, PJF occurred in 43 patients (21.9%). Multivariate logistic regression analysis revealed that old age (odds ratio [OR], 1.063; 95% confidence interval [CI], 1.001–1.129; p=0.046), large preoperative sagittal vertical axis (OR, 1.007; 95% CI, 1.001–1.013; p=0.024), nonuse of a transverse process (TP) hook (OR, 5.556; 95% CI, 1.205–19.621; p=0.028), and high lumbar distribution index (LDI) (OR, 1.136; 95% CI, 1.109–1.164; p<0.001) were significant risk factors for PJF development.
Conclusion
A sizeable proportion of patients (21.9%) developed PJF despite achieving ideal sagittal correction. Using TP hooks with avoiding excessive LDI can be helpful to further mitigate the risk of PJF development in this patient group.

Citations

Citations to this article as recorded by  Crossref logo
  • Association between lumbar lordosis and proximal junctional failure following adult spinal deformity surgery: a systematic review and meta-analysis
    Abdullah M. Alharran, AbdulMuhsen AlQallaf, Mohammad Mohammad, Mohammad Salem Alajmi, Mohammad Alkaak, Salem Y. Alenezi, Fahad Mohammad, Ahmad Al Ahmad, Nizar Algarni, Yousef Marwan
    Spine Deformity.2026; 14(4): 1051.     CrossRef
  • Does Preoperative Spinal Alignment Influence Surgical Outcomes When Postoperative Alignment and Fixation Strategies Are Matched in ASD Correction?
    Donghua Huang, Zhan Wang, Michael Jian-Wen Chen, Annika Bay, Robert N. Uzzo, Gabrielle Dykhouse, Atahan Durbas, Andrea Pezzi, Stephane Owusu-Sarpong, Luis Felipe Colon, Kasra Araghi, Quante Singleton, Farah Musharbash, Sereen Halayqeh, Matthew E. Cunningh
    Spine.2026; 51(11): 761.     CrossRef
  • Proximal Junctional Kyphosis Prevention in Adult Spinal Deformity Surgery: A Technical Review of Tethering and Adjunctive Strategies
    Paritash Tahmasebpour, Pawel P. Jankowski, Jason Liang, Joshua Lin, Kyriakos D. Chatzis, Peter S. Tretiakov, Spencer Matthews, Louis Boissiere, John F. Burke, Christopher I. Shaffrey, Aaron Hockley, Peter Passias
    Operative Neurosurgery.2026;[Epub]     CrossRef
  • Machine learning–based identification of distinct risk factors for moderate versus severe proximal junctional kyphosis after adult spinal deformity surgery
    Dong-Ho Kang, Jin-Sung Park, Chong-Suh Lee, Se-Jun Park
    The Spine Journal.2026;[Epub]     CrossRef
  • The use of hooks in upper instrumented vertebra to prevent proximal junctional complications: a systematic review and meta-analysis
    Hifza Babar, Dong Li, Jie Li, Zhen Liu, Zezhang Zhu, Yong Qiu
    BMC Surgery.2026;[Epub]     CrossRef
  • Utility of Enabling Technologies in Spinal Deformity Surgery: Optimizing Surgical Planning and Intraoperative Execution to Maximize Patient Outcomes
    Nora C. Kim, Eli Johnson, Christopher DeWald, Nathan Lee, Timothy Y. Wang
    Journal of Clinical Medicine.2025; 14(15): 5377.     CrossRef
  • Postoperative L1 Tilt as a Predictor of Proximal Junctional Kyphosis Following Lower Thoracic Spine-to-Pelvis Fusion for Adult Spinal Deformity
    Se-Jun Park, Jin-Sung Park, Dong-Ho Kang, Kyunghun Jung, Minwook Kang, Chong-Suh Lee
    Spine.2025; 50(24): 1769.     CrossRef
  • From the Editor-in-Chief: Featured Articles in the December 2024 Issue
    Inbo Han
    Neurospine.2024; 21(4): 1051.     CrossRef
  • Risk Factors, Biomechanics, and Prevention Strategies for Proximal Junctional Failure in Adult Spinal Deformity Surgery – A Commentary on “Proximal Junctional Failure Development Despite Achieving Ideal Sagittal Correction According to Age-Adjusted Alignm
    Lee A. Tan
    Neurospine.2024; 21(4): 1094.     CrossRef
  • New Insights Into Risk Factors for Proximal Junctional Failure in Adult Spinal Deformity Surgery – A Commentary on “Proximal Junctional Failure Development Despite Achieving Ideal Sagittal Correction According to Age-Adjusted Alignment Target in Patients
    Masayuki Miyagi, Gen Inoue, Masashi Takaso
    Neurospine.2024; 21(4): 1091.     CrossRef
  • 7,494 View
  • 292 Download
  • 10 Crossref

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Influence of Lumbar Lordosis on Posterior Rod Strain in Long-Segment Construct During Biomechanical Loading: A Cadaveric Study
Neurospine. 2021;18(3):635-643.   Published online September 30, 2021
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Influence of Lumbar Lordosis on Posterior Rod Strain in Long-Segment Construct During Biomechanical Loading: A Cadaveric Study
Neurospine. 2021;18(3):635-643.   Published online September 30, 2021
Close
Objective
The lordotic shape of the lumbar spine differs substantially between individuals. Measuring and recording strain during spinal biomechanical tests is an effective method to infer stresses on spinal implants and predict failure mechanisms. The geometry of the spine may have a significant effect on the resultant force distribution, thereby directly affecting rod strain.
Methods
Seven fresh-frozen cadaveric specimens (T12-sacrum) underwent standard (7.5 Nm) nondestructive sagittal plane tests: flexion and extension. The conditions tested were intact and pedicle screws and rods (PSR) at L1-sacrum. The posterior right rod was instrumented with strain gauges between L3–4 (index level) and the L5–S1 pedicle screw. All specimens underwent lateral radiographs before testing. Lordotic angles encompassing different levels (L5–S1, L4–S1, L3–S1, L2–S1, and L1–S1) were measured and compared with rod strain. Data were analyzed using Pearson correlation analyses.
Results
Strong positive correlations were observed between lordosis and posterior rod strain across different conditions. The L3–S1 lordotic angle in the unloaded intact condition correlated with peak rod strain at L3–4 with PSR during flexion (R = 0.76, p = 0.04). The same angle in the unloaded PSR condition correlated with peak strain in the PSR condition during extension (R = -0.79, p = 0.04). The unloaded intact L2–S1 lordotic angle was significantly correlated with rod strain at L3–4 in the PSR condition during flexion (R = 0.85, p = 0.02) and extension (R = -0.85, p = 0.02) and with rod strain at L5–S1 in the PSR condition during flexion (R = 0.84, p = 0.04).
Conclusion
Lordosis measured on intact and instrumented conditions has strong positive correlations with posterior rod strain in cadaveric testing.

Citations

Citations to this article as recorded by  Crossref logo
  • Machine learning models for predicting treatment outcomes in chronic non-specific back pain patients undergoing lumbar extension traction
    Ibrahim M. Moustafa, Dilber Uzun Ozsahin, Mubarak Taiwo Mustapha, Shima Zadeh, Iman Khowailed, Paul A. Oakley, Deed E. Harrison
    Scientific Reports.2026;[Epub]     CrossRef
  • Acute pelvic fixation failure in adult spinal deformity-risk factors and tips and pearls for management
    Kari Odland, Christopher T. Martin
    Seminars in Spine Surgery.2026; 38(2): 101254.     CrossRef
  • Impact of transforaminal lumbar interbody fusion on rod load: a comparative biomechanical analysis between a cadaveric instrumentation and simulated bone fusion
    Maximilian Heumann, Chencheng Feng, Lorin M. Benneker, Maarten Spruit, Christian Mazel, Jan Buschbaum, Boyko Gueorguiev, Manuela Ernst
    Medical Engineering & Physics.2025; 139: 104339.     CrossRef
  • Comparison of posterior trans-intervertebral osteotomy and pedicle Subtraction osteotomy for the correction of thoracolumbar kyphotic deformity secondary to ankylosing spondylitis
    Lijin Zhou, Honghao Yang, Jie Wang, Yiqi Zhang, Yunsheng Wang, Yong Hai
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Analysis of the association between lumbar paraspinal muscle atrophy, facet joint degeneration, and degenerative lumbar scoliosis
    Jiangkai Yu, Cong Zhang, Yan Zhou, Chengming Li
    European Journal of Medical Research.2025;[Epub]     CrossRef
  • Biomechanical evaluation of multi-rod constructs to stabilize an S1 pedicle subtraction osteotomy (PSO): a finite element analysis
    Niloufar Shekouhi, Sudharshan Tripathi, Vijay K. Goel, Alekos A. Theologis
    Spine Deformity.2024; 12(2): 313.     CrossRef
  • Torque forces of expandable titanium vertebral body replacement cages during expansion and subsidence in the osteoporotic lumbar spine
    Krishnan Sircar, Maximilian Weber, Sebastian G. Walter, Nadine Ott, Andreas Prescher, Peer Eysel, Nikolaus Kernich
    Clinical Biomechanics.2024; 114: 106239.     CrossRef
  • How common is acute pelvic fixation failure after adult spine surgery? A single-center study of 358 patients
    Nathan J. Lee, Paul J. Park, Varun Puvanesarajah, William E. Clifton, Kevin Kwan, Cole R. Morrissette, Jaques L. Williams, Michael W. Fields, Eric Leung, Fthimnir M. Hassan, Peter D. Angevine, Christopher E. Mandigo, Joseph M. Lombardi, Zeeshan M. Sardar,
    Journal of Neurosurgery: Spine.2023; 38(1): 91.     CrossRef
  • Cross-link augmentation enhances CFR-PEEK short fixation in lumbar metastasis stabilization
    Simone Borrelli, Giovanni Putame, Alberto L. Audenino, Cristina Bignardi, Andrea Ferro, Stefano Marone, Mara Terzini
    Frontiers in Bioengineering and Biotechnology.2023;[Epub]     CrossRef
  • Radiological Outcomes of Unilateral Laminotomy for Bilateral Decompression in Lumbar Spinal Stenosis With and Without Discectomy
    Hyun-Seo Cho, Se-Hoon Kim, Jeong Su Han, Bum-Joon Kim
    World Neurosurgery.2023; 175: e1307.     CrossRef
  • Mechanical Failure After Total En Bloc Spondylectomy and Salvage Surgery
    Shin Won Kwon, Chun Kee Chung, Young Il Won, Woon Tak Yuh, Sung Bae Park, Seung Heon Yang, Chang Hyun Lee, John M. Rhee, Kyoung-Tae Kim, Chi Heon Kim
    Neurospine.2022; 19(1): 146.     CrossRef
  • Incidence, mechanism, and protective strategies for 2-year pelvic fixation failure after adult spinal deformity surgery with a minimum six-level fusion
    Nathan J. Lee, Gerard Marciano, Varun Puvanesarajah, Paul J. Park, William E. Clifton, Kevin Kwan, Cole R. Morrissette, Jaques L. Williams, Michael Fields, Fthimnir M. Hassan, Peter D. Angevine, Christopher E. Mandigo, Joseph M. Lombardi, Zeeshan M. Sarda
    Journal of Neurosurgery: Spine.2022; : 1.     CrossRef
  • 9,637 View
  • 126 Download
  • 12 Web of Science
  • 12 Crossref

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A Hybrid Dynamic Stabilization and Fusion System in Multilevel Lumbar Spondylosis
Neurospine. 2018;15(3):231-241.   Published online August 22, 2018
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A Hybrid Dynamic Stabilization and Fusion System in Multilevel Lumbar Spondylosis
Neurospine. 2018;15(3):231-241.   Published online August 22, 2018
Close
Objective
The Dynesys-Transition-Optima (DTO) hybrid system was designed to achieve arthrodesis and stabilization in patients with lumbar degeneration. Satisfactory outcomes were demonstrated previously. However, no study has evaluated the effects of using the DTO system in patients with lumbar spondylolisthesis or stenosis.
Methods
This retrospective study included 35 consecutive patients with multilevel lumbar degeneration with or without spondylolisthesis who underwent surgery using the DTO system. Imaging studies included pre- and postoperative radiography, magnetic resonance imaging, and computed tomography. The clinical outcomes were measured by Japanese Orthopedic Association (JOA) scores, Oswestry Disability Index (ODI) scores, and a visual analogue scale (VAS) for back and leg pain.
Results
Thirty patients (85.7%) with a mean age of 61.9 years completed the follow-up, with a mean duration of 35.1 months. There were 21 patients in the spondylolisthesis group and 9 in the stenosis group. The spondylolisthesis group had worse functional scores than the stenosis group preoperatively. After DTO surgery, all patients showed significant improvements in clinical outcomes, including VAS for back and leg pain, ODI, and JOA scores (p < 0.05). There were no significant differences in clinical outcomes between the 2 groups. At a 2-year follow-up, lumbar alignment was well maintained in both groups (p = 0.116). There were no significant differences in lumbar alignment between the 2 groups.
Conclusion
During a follow-up period of over 2 years, both patients with spondylolisthesis and those with stenosis showed improvements and similar disability and pain scores after surgery using the DTO system. Lumbar alignment was also well maintained.

Citations

Citations to this article as recorded by  Crossref logo
  • The Effect of Osteopenia and Osteoporosis on Screw Loosening in MIS-TLIF and Dynamic Stabilization
    Hsuan-Kan Chang, Chih-Chang Chang, Yu-Wen Cheng, Ching-Lan Wu, Tsung-Hsi Tu, Jau-Ching Wu, Wen-Cheng Huang
    Global Spine Journal.2025; 15(4): 2209.     CrossRef
  • Biomechanical Analysis and Mid-Term Clinical Outcomes of the Dynamic-Transitional Optima Hybrid Lumbar Device
    Shih-Hao Chen, Shang-Chih Lin, Chi-Ruei Li, Zheng-Cheng Zhong, Chih-Ming Kao, Mao-Shih Lin, Hsi-Kai Tsou
    Journal of Clinical Medicine.2025; 14(22): 8087.     CrossRef
  • A Retrospective Observational Study to Evaluate Adjacent Segmental Degenerative Change with the Dynesys-Transition-Optima Instrumentation System
    Chi-Ruei Li, Shih-Hao Chen, Wen-Hsien Chen, Hsi-Kai Tsou, Chung-Yuh Tzeng, Tse-Yu Chen, Mao-Shih Lin
    Journal of Clinical Medicine.2024; 13(2): 582.     CrossRef
  • A Biomechanical Comparison of 2 Different Topping-off Devices and Their Influence on the Sacroiliac Joint Following Lumbosacral Fusion Surgery
    Wei Fan, Song Yang, Jie Chen, Li-Xin Guo, Ming Zhang
    Neurospine.2024; 21(1): 244.     CrossRef
  • Comparison of Cortical Bone Trajectory to Pedicle-Based Dynamic Stabilization: An Analysis of 291 Patients
    Chih-Chang Chang, Hsuan-Kan Chang, Chin-Chu Ko, Ching-Lan Wu, Yi-Hsuan Kuo, Tsung-Hsi Tu, Wen-Cheng Huang, Jau-Ching Wu
    Neurospine.2023; 20(1): 308.     CrossRef
  • Biomechanical and clinical research of Isobar semi-rigid stabilization devices for lumbar degenerative diseases: a systematic review
    Jianbin Guan, Tao Liu, Xing Yu, Wenhao Li, Ningning Feng, Guozheng Jiang, He Zhao, Yongdong Yang
    BioMedical Engineering OnLine.2023;[Epub]     CrossRef
  • Cortical Bone Trajectory-Based Dynamic Stabilization
    Yi-Hsuan Kuo, Chao-Hung Kuo, Hsuan-Kan Chang, Chin-Chu Ko, Tsung-Hsi Tu, Chih-Chang Chang, Henrich Cheng, Jiing-Feng Lirng, Wen-Cheng Huang, Jau-Ching Wu
    World Neurosurgery.2022; 159: e416.     CrossRef
  • Efficacy of the Dynesys Hybrid Surgery for Patients with Multi-Segmental Lumbar Spinal Stenosis
    Xiao Xiao, Gaoyang Chen, Song Wang, Junliang Liu, Erhu Lin, Ke Chen, Yucheng Xiang, Ke Zhan, Congcong Liu, Zhengbin Yuan, Minjie Yang, Shuyuan Zhong, Wanxin Zhen, Dazhi Yang, Songlin Peng
    Frontiers in Surgery.2022;[Epub]     CrossRef
  • Biomechanical Effect of Hybrid Dynamic Stabilization Implant on the Segmental Motion and Intradiscal Pressure in Human Lumbar Spine
    Chih-Kun Hsiao, Yi-Jung Tsai, Cheng-Yo Yen, Yi-Chen Li, Hao-Yuan Hsiao, Yuan-Kun Tu
    Bioengineering.2022; 10(1): 31.     CrossRef
  • The Efficacy of Lumbar Hybrid Fusion for the Prevention of Adjacent Segment Disease
    Hyun-Jae Cho, Young San Ko, Young Il Won, Chang-Hyun Lee, Seung Heon Yang, Chi Heon Kim, Chun Kee Chung
    Clinical Spine Surgery.2021; 34(7): 260.     CrossRef
  • Correlation of bone density to screw loosening in dynamic stabilization: an analysis of 176 patients
    Hsuan-Kan Chang, Jason Ku, Johnson Ku, Yi-Hsuan Kuo, Chih-Chang Chang, Ching-Lan Wu, Jiing-Feng Lirng, Jau-Ching Wu, Wen-Cheng Huang, Henrich Cheng, Shih-Ming Hsu
    Scientific Reports.2021;[Epub]     CrossRef
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    Liehua Liu, Lei Luo, Chen Zhao, Qiang Zhou, Sidong Yang
    Pain Research and Management.2021; 2021: 1.     CrossRef
  • Experimental Comparison of Autograft and DBM Flex (Grafton) for Spinal Lumbar Fusion in Rabbits
    Cem DEMİREL, Dursun TÜRKÖZ, Tuncay YİLMAZ
    Archives of Clinical and Experimental Medicine.2021; 6(3): 153.     CrossRef
  • Comparison of Radiation Exposure Between O-Arm Navigated and C-Arm Guided Screw Placement in Minimally Invasive Transforaminal Lumbar Interbody Fusion
    Chih-Chang Chang, Hsuan-Kan Chang, Jau-Ching Wu, Tsung-Hsi Tu, Henrich Cheng, Wen-Cheng Huang
    World Neurosurgery.2020; 139: e489.     CrossRef
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    Hongbo Wang, Jun Peng, Qingshen Zeng, Yanchun Zhong, Chunlin Xiao, Yongjun Ye, Weimin Huang, Wuyang Liu, Jiaquan Luo
    Medicine.2020; 99(21): e19784.     CrossRef
  • Comparison of Fusion Rate between Demineralized Bone Matrix versus Autograft in Lumbar Fusion : Meta-Analysis
    Sanghyun Han, Bumsoo Park, Jeong-Wook Lim, Jin-Young Youm, Seoung-Won Choi, Dae Hwan Kim, Dong Ki Ahn
    Journal of Korean Neurosurgical Society.2020; 63(6): 673.     CrossRef
  • Commentary: Low-Grade Infection and Implant Failure Following Spinal Instrumentation: A Prospective Comparative Study
    Hsuan-Kan Chang, Wen-Cheng Huang, Jau-Ching Wu
    Neurosurgery.2020; 87(5): E541.     CrossRef
  • Effects of smoking on pedicle screw–based dynamic stabilization: radiological and clinical evaluations of screw loosening in 306 patients
    Yi-Hsuan Kuo, Chao-Hung Kuo, Hsuan-Kan Chang, Tsung-Hsi Tu, Li-Yu Fay, Chih-Chang Chang, Henrich Cheng, Ching-Lan Wu, Jiing-Feng Lirng, Jau-Ching Wu, Wen-Cheng Huang
    Journal of Neurosurgery: Spine.2020; 33(3): 398.     CrossRef
  • Comparative Finite Element Analysis of Lumbar Cortical Screws and Pedicle Screws in Transforaminal and Posterior Lumbar Interbody Fusion
    Dong Ah Sin, Dong Hwa Heo
    Neurospine.2019; 16(2): 298.     CrossRef
  • 14,236 View
  • 201 Download
  • 19 Web of Science
  • 19 Crossref