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Transforaminal Endoscopic Lumbar Foraminotomy for Iatrogenic Foraminal Stenosis Following Vertebroplasty
Neurospine. 2024;21(4):1137-1140.   Published online December 31, 2024
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Transforaminal Endoscopic Lumbar Foraminotomy for Iatrogenic Foraminal Stenosis Following Vertebroplasty
Neurospine. 2024;21(4):1137-1140.   Published online December 31, 2024
Close
We present a case of iatrogenic lumbar foraminal stenosis caused by bone-cement leakage during vertebroplasty, successfully managed using transforaminal endoscopic lumbar foraminotomy (TELF). Vertebroplasty is an effective treatment for osteoporotic vertebral compression fractures (VCFs); however, complications such as bone-cement leakage can lead to vascular or neurological issues, including lumbar radiculopathy. TELF is a minimally invasive surgical option for addressing various forms of lumbar foraminal stenosis. An 82-year-old female patient presented to Gachon University Gil Medical Center with severe right inguinal pain radiating to the anterior thigh and knee. Six months prior, she had undergone vertebroplasty at the L3 level for an osteoporotic VCF at another hospital. Following the procedure, she developed radicular leg pain with a diminished knee jerk reflex, which progressively worsened despite extensive conservative treatment. Magnetic resonance imaging and computed tomography revealed right-sided L3–4 foraminal stenosis caused by bone-cement leakage from the prior vertebroplasty. TELF was performed under local anesthesia to decompress the affected area. Bone-cement fragments, along with hypertrophic bone and ligaments, were successfully removed, achieving sufficient decompression of the exiting nerve root. The patient experienced immediate postoperative pain relief. This case represents the first documented instance of endoscopic decompression for iatrogenic foraminal stenosis following vertebroplasty. TELF, performed safely under local anesthesia, demonstrates its effectiveness as a minimally invasive solution for this rare complication.

Citations

Citations to this article as recorded by  Crossref logo
  • Cement leakage into adjacent vertebra during percutaneous vertebroplasty: “Gild the Lily” or “Kill two birds with one stone”?
    Rui-Feng Ji, De-an Qin
    International Journal of Surgery.2026;[Epub]     CrossRef
  • Current Evidence and Clinical Implications of Full-Endoscopic Spine Surgery for Post-Vertebroplasty Lumbar Radiculopathy: A Comprehensive Review
    Yong Ahn, Sol Lee, Chang Won Lee
    Journal of Pain Research.2026; Volume 19: 1.     CrossRef
  • O-arm navigation-based transforaminal unilateral biportal endoscopic discectomy for upper lumbar disc herniation: an innovative preliminary study
    Dong Hyun Lee, Choon Keun Park, Jin-Sung Kim, Jin Sub Hwang, Jin Young Lee, Dong-Geun Lee, Jae-Won Jang, Jun Yong Kim, Yong-Eun Cho, Dong Chan Lee
    Asian Spine Journal.2025; 19(2): 194.     CrossRef
  • Risk factors analysis of recurrent vertebral fractures after vertebroplasty
    Wei Wu, Kai Zhou, Bo Yang, Xianjin Luo
    Current Problems in Surgery.2025; 70: 101836.     CrossRef
  • 3,212 View
  • 83 Download
  • 3 Web of Science
  • 4 Crossref

Original Articles

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Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion
Neurospine. 2023;20(2):553-563.   Published online June 30, 2023
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Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion
Neurospine. 2023;20(2):553-563.   Published online June 30, 2023
Close
Objective
Conventional oblique lumbar interbody fusion (OLIF) approach is possible from the L2/3 to L4/5 levels. However, obstruction of the lower ribs (10th–12th) makes it difficult to maintain disc parallel maneuvers or orthogonal maneuvers. To overcome these limitations, we proposed an intercostal retroperitoneal (ICRP) approach to access the upper lumbar spine. This method does not expose the parietal pleura or require rib resection and employs a small incision.
Methods
We enrolled patients who underwent a lateral interbody procedure on the upper lumbar spine (L1/2/3). We compared the incidence of endplate injury between conventional OLIF and ICRP approaches. In addition, by measuring the rib line, the difference in endplate injury according to rib location and approach was analyzed. We also analyzed the previous period (2018–2021) and the year 2022, when the ICRP has been actively applied.
Results
A total of 121 patients underwent lateral interbody fusion to the upper lumbar spine (OLIF approach, 99 patients; ICRP approach, 22 patients). Endplate injuries occurred in 34 of 99 (34.3%) and 2 of 22 patients (9.1%) during the conventional and ICRP approaches, respectively (p = 0.037; odds ratio, 5.23). When the rib line was located at the L2/3 disc or L3 body, the endplate injury rate was 52.6% (20 of 38) for the OLIF approach but 15.4% (2 of 13) for the ICRP approach. Since 2022, the proportion of OLIF including L1/2/3 levels has increased 2.9-fold.
Conclusion
The ICRP approach is effective in reducing the incidence of endplate injury in patients with a relatively lower rib line, without pleural exposure or rib resection.

Citations

Citations to this article as recorded by  Crossref logo
  • Clinical Characterization of Lymphatic Leakage Complicating OLIF Surgery
    Hanli Yang, Dan Zhang, Wenjie Zhang, Man Luo, Liwei Wang, Yuanming Zhong, Ming Shi
    Clinical Spine Surgery.2026; 39(1): 1.     CrossRef
  • The Minimally Invasive Intercostal Subdiaphragmatic Access without Rib Resection for Lateral Lumbar Interbody Fusion at L1/2: Surgical Techniques and Cases Illustration
    Teerachat Tanasansomboon, Jerry Robinson, Wicharn Yingsakmongkol, Worawat Limthongkul, Weerasak Singhatanadgige, Vit Kotheeranurak, Piyanat Wangsawatwong, Babak Khandehroo, Neel Anand
    World Neurosurgery.2025; 194: 123564.     CrossRef
  • How to choose rib resection in minimally invasive lateral approach thoracolumbar junction corpectomy: radiographic analysis and case illustrations
    Fengyu Liu, Zhenfang Gu, Xianze Sun, Xianzhong Meng
    Frontiers in Surgery.2025;[Epub]     CrossRef
  • Anterior-to-psoas OLIF: Surgical approach, issues & technical nuances
    Stjepan Ivandić, Jure Pavešić, Stipe Ćorluka, Tomislav Čengić
    Seminars in Spine Surgery.2025; 37(1): 101159.     CrossRef
  • L2/3, L3/4 and L4/5 oblique lumbar interbody fusion/anterior to psoas: Anatomical and technical considerations
    Prashanth J Rao, Nipun Shreshtha, Gayani Petersingham, Andrew J Berg, Kevin Seex
    Seminars in Spine Surgery.2025; 37(1): 101162.     CrossRef
  • Radiological Outcomes and Approach-Related Complications in Oblique Lateral Interbody Fusion at the Upper Lumbar Level
    Hee-Woong Chung, Han-Dong Lee, Myungsub Lee, Nam-Su Chung
    Journal of Clinical Medicine.2025; 14(10): 3333.     CrossRef
  • Prediction of Angle Loss after L4/5 Oblique Lumbar Interbody Fusion : Development of a Risk Stratification Model
    Se-Woon Kim, Su-Hun Lee, Jun-Seok Lee, Chi-Hyung Lee, Chang-Hyun Kim, Soon-Ki Sung, Dong-Wuk Son, Sang-Weon Lee
    Journal of Korean Neurosurgical Society.2025; 68(6): 724.     CrossRef
  • A Comprehensive Analysis of Potential Complications after Oblique Lumbar Interbody Fusion : A Review of Postoperative Magnetic Resonance Scans in Over 400 Cases
    Kang-Hoon Lee, Su-Hun Lee, Jun-Seok Lee, Young-Ha Kim, Soon-Ki Sung, Dong-Wuk Son, Sang-Weon Lee, Geun-Sung Song
    Journal of Korean Neurosurgical Society.2024; 67(5): 550.     CrossRef
  • Commentary on “Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion”
    Alexander E. Ropper
    Neurospine.2023; 20(2): 564.     CrossRef
  • From the Editor-in-Chief: Featured Articles in the June 2023 Issue
    Inbo Han
    Neurospine.2023; 20(2): 413.     CrossRef
  • 6,760 View
  • 244 Download
  • 8 Web of Science
  • 10 Crossref

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Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With Lumbar Degenerative Disease
Neurospine. 2023;20(2):536-549.   Published online June 27, 2023
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Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With Lumbar Degenerative Disease
Neurospine. 2023;20(2):536-549.   Published online June 27, 2023
Close
Objective
To compare the efficacy of oblique lateral interbody fusion (OLIF), OLIF combined with anterolateral screw fixation (OLIF-AF), and OLIF combined with percutaneous pedicle screw fixation (OLIF-PF) in the treatment of single-level or 2-level degenerative lumbar disease.
Methods
Between January 2017 and 2021, 71 patients were treated with OLIF and combined OLIF. The demographic data, clinical outcomes, radiographic outcomes, and complications were compared among the 3 groups.
Results
The operative time and intraoperative blood loss in the OLIF (p<0.05) and OLIF-AF (p<0.05) groups were lower than in the OLIF-PF group. Posterior disk height improvement in the OLIF-PF group was better than in the OLIF (p<0.05) and OLIF-AF (p<0.05) groups. In terms of foraminal height (FH), the OLIF-PF group was significantly better than the OLIF group (p<0.05), but there was no significant difference between the OLIF-PF and OLIF-AF groups (p>0.05) or between the OLIF and OLIF-AF groups (p>0.05). There were no significant differences in fusion rates, the incidence of complications, lumbar lordosis, anterior disc height, and cross-sectional area among the 3 groups (p>0.05). The OLIF-PF group had significantly lower rates of subsidence than the OLIF group (p<0.05).
Conclusion
OLIF remains a viable option with similar patient-reported outcomes and fusion rates compared with surgeries that include lateral and posterior internal fixation while greatly reducing the financial burden, intraoperative time, and intraoperative blood loss. OLIF has a higher subsidence rate than lateral and posterior internal fixation, but most subsidence is mild and has no adverse effect on clinical and radiographic outcomes.

Citations

Citations to this article as recorded by  Crossref logo
  • Biomechanical evaluation of a novel L-shaped side-locking plate combined with OLIF: a finite element analysis considering 3 different bone densities
    Zemin Wang, Lijun Wang, Honglai Zhang, Wei Guo, Wei Yang, Wanzhong Yang, Shiyong Wang, Rong Ma, Zhaohui Ge
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Comparison of clinical outcomes between unilateral biportal endoscopic transforaminal lumbar interbody fusion and oblique lumbar interbody fusion with posterior percutaneous screw fixation in patients with lumbar spinal canal stenosis
    Ye-Hui Wang, Xiang Gao, You-Peng Hu, Guo-Sheng Tang, Wei Cui, Shi-Peng Yang, Si-Mao Song, Wei Hou, Xuan-Geng Deng
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Oblique Lumbar Interbody Fusion Combined With Anterolateral Fixation and Cement Augmentation for the Treatment of Degenerative Lumbar Diseases in the Elderly Population: A Retrospective Study
    Weiqi Han, Lei He, Fei Wang, Xiaofeng Zhao, Cong Jin
    Orthopaedic Surgery.2025; 17(2): 446.     CrossRef
  • Biomechanical insights into anterolateral vertebral screw fixation in osteoporotic spines: a comparative study of fixation methods and positions using porcine vertebrae
    Ming-Kai Hsieh, Yun-Da Li, Weng-Pin Chen, De-Mei Lee, Ching-Lung Tai
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Differences in radiographic and clinical outcomes of different oblique lumbar interbody fusions for lumbar degenerative diseases: a systematic review and Bayesian network meta-analysis
    Zhiyuan Dai, Haomiao Yang, Yinjia Yan, Shuhe Zhu, Weiqing Qian
    Neurosurgical Review.2025;[Epub]     CrossRef
  • Therapy Potential of Oblique Lumbar Interbody Fusion 360 for Severe Lumbar Spinal Stenosis
    Lei Li, Yan Wang, Hao Zhang, Jialuo Han, Changpeng Qu, Yihao Sun, Hao Tao, Xuexiao Ma
    Orthopaedic Surgery.2025; 17(4): 1114.     CrossRef
  • Biomechanical Comparison of a Novel Facet Joint Fusion Fixation Device With Conventional Pedicle Screw Fixation Device: A Finite Element Analysis
    Feilong Sun, Haiyang Qiu, Yufei Ji, Longchao Wang, Wei Lei, Yang Zhang
    Orthopaedic Surgery.2025; 17(4): 1230.     CrossRef
  • Analysis of the therapeutic efficacy of OLIF combined with posterior percutaneous pedicle screw fixation in the treatment of patients with primary lumbar spondylodiscitis
    Liang Deng, Yu Zhou, Moliang Xiong, Jihuan Zeng, Caiguang Luo, Jia Guo, Qiang Xiao
    Frontiers in Surgery.2025;[Epub]     CrossRef
  • Oblique lumbar interbody fusion (OLIF) implants and lumbar disc replacement: Design, current status, and future directions
    Stipe Ćorluka, Stjepan Ivandić, Mišo Krstičević, Tomislav Čengić
    Seminars in Spine Surgery.2025; 37(1): 101165.     CrossRef
  • Biomechanical evaluation of various fixation strategies in oblique lumbar interbody fusion: a finite element analysis
    Jinyue He, Jiezhong Deng, Yu Xiang, Yusheng Yang, Sheng Liao, Hui Chen, Fei Luo, Jianzhong Xu, Zhongrong Zhang, Zehua Zhang
    BMC Musculoskeletal Disorders.2025;[Epub]     CrossRef
  • Comparison of oblique lumbar interbody fusion with pedicle screw fixation versus stress endplate augmentation and anterolateral screw fixation for degenerative lumbar spinal stenosis in osteoporotic patients
    Jiahong Nong, Zhuhai Li, Xiaoping Mu, Jiacheng Jin, Dayang Shi, Haoxi Li, Zhengyi Huang, Zhanghua Wu, Yan Mo, Jianxun Wei
    European Spine Journal.2025; 34(12): 5664.     CrossRef
  • MRI-based vertebral and endplate bone quality scores for assessing patient suitability in oblique lumbar interbody fusion with anterolateral screw fixation
    Jiacheng Jin, Zhuhai Li, Xiaoping Mu, Jiahong Nong, Xiaodong Wei, Fuyu Chen, Dayang Shi, Tingsheng Lu, Lihang Wang, Haoxi Li, Jianxun Wei
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Biomechanics of Cage for Stand-alone Oblique Lumbar Interbody Fusion
    Xiaohua Li, Shangju Gao, Jingchao Wei, Yusong Guo, Kuan Lu, Wenyi Li, Shuai Wang, Ting Li
    Clinical Spine Surgery.2025;[Epub]     CrossRef
  • Two minimally invasive fusion techniques for neurogenic claudication caused by degenerative lumbar spondylolisthesis: a minimum 2-year follow-up study
    Wei Cui, Yehui Wang, Wei Hou, Xuangeng Deng
    Frontiers in Neurology.2025;[Epub]     CrossRef
  • A retrospective study identifying the primary source of hidden blood loss during vertebroplasty
    Yuanhao Wang, Ting Zhao, Cong Chen, Baoshan Xu
    Medicine.2025; 104(42): e45213.     CrossRef
  • Risk Factors of Cage Subsidence Following Oblique Lumbar Interbody Fusion: A Meta-analysis and Systematic Review
    Shufeng Shen, Xinmao You, Yingqing Ren, Senqi Ye
    World Neurosurgery.2024; 183: 180.     CrossRef
  • Screening patients requiring secondary lumbar surgery for degenerative lumbar spine diseases: a nationwide sample cohort study
    Hangeul Park, Juhee Lee, Yunhee Choi, Jun-Hoe Kim, Sum Kim, Young-Rak Kim, Chang-Hyun Lee, Sung Bae Park, Kyoung-Tae Kim, John M. Rhee, Chi Heon Kim
    Scientific Reports.2024;[Epub]     CrossRef
  • Comparison of Lumbar Interbody Fusion with 3D-Printed Porous Titanium Cage Versus Polyetheretherketone Cage in Treating Lumbar Degenerative Disease: A Systematic Review and Meta-Analysis
    Yuchen Duan, Dagang Feng, Tong Li, Yiran Wang, Leiming Jiang, Yong Huang
    World Neurosurgery.2024; 183: 144.     CrossRef
  • Development and Current Status of Anterior Lumbar Interbody Fusion Surgical Techniques
    昊天 吴
    Advances in Clinical Medicine.2024; 14(01): 1715.     CrossRef
  • Comparison of biomechanical effects of polyetheretherketone (PEEK) rods and titanium rods in lumbar long-segment instrumentation: a finite element study
    Chao Li, Yao Zhao, Longtao Qi, Beiyu Xu, Lei Yue, Ranlyu Zhu, Chunde Li
    Frontiers in Bioengineering and Biotechnology.2024;[Epub]     CrossRef
  • Comparative effectiveness of oblique lumbar interbody fusion with anterior screw fixation versus percutaneous pedicle screw fixation for treating lumbar degenerative diseases: A systematic review and meta-analysis
    Laveeza Fatima, Sameer S Tebha, Rabeya Farid, Aemen Kamran, Sravan KR Edamakanti, Mohammad F Farrukh
    Journal of Orthopaedic Surgery.2024;[Epub]     CrossRef
  • The Clinical Application and Research Progress of Oblique Lumbar Interbody Fusion (OLIF)
    朝硕 刘
    Advances in Clinical Medicine.2024; 14(10): 1317.     CrossRef
  • Commentary on “Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With
    Chang Il Ju
    Neurospine.2023; 20(2): 550.     CrossRef
  • Clinical, Radiographic and Fusion Comparison of Oblique Lumbar Interbody Fusion (OLIF) stand-alone and OLIF with posterior pedicle screw fixation in patients with degenerative spondylolisthesis
    Wenhao Zhao, Chuanli Zhou, Hao Zhang, Jianwei Guo, Jialuo Han, Antao Lin, Yan Wang, Xuexiao Ma
    BMC Musculoskeletal Disorders.2023;[Epub]     CrossRef
  • Simultaneous Single-Position Oblique Lateral Interbody Fusion Combined With Unilateral Percutaneous Pedicle Screw Fixation for Single-Level Lumbar Tuberculosis: A 3-Year Retrospective Comparative Study
    Jinyue He, Jiezhong Deng, Yusheng Yang, Tingting Zheng, Fei Luo, Jianzhong Xu, Zehua Zhang
    Neurospine.2023; 20(4): 1306.     CrossRef
  • 6,663 View
  • 229 Download
  • 24 Web of Science
  • 25 Crossref

NASS/Neurospine Endoscopic Spine Surgery Special Issue

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The Use of Dual Direction Expandable Titanium Cage With Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: A Technical Consideration With Preliminary Results
Neurospine. 2023;20(1):110-118.   Published online March 31, 2023
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The Use of Dual Direction Expandable Titanium Cage With Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: A Technical Consideration With Preliminary Results
Neurospine. 2023;20(1):110-118.   Published online March 31, 2023
Close
Objective
Expandable cage technology has emerged for lumbar interbody fusion to restore intervertebral disc space height and alignment through a narrow surgical corridor. The purpose of this study is to present the technique of biportal endoscopic transforaminal lumbar interbody fusion (TLIF) using dual direction expandable cage and provide early clinical results.
Methods
We performed the biportal endoscopic TLIF using a dual direction expandable titanium cage for height restoration and a larger footprint in 10 patients. Clinical parameters including Oswestry Disability Index (ODI), visual analogue scale (VAS), and complications were retrospectively analyzed. Also, we investigated radiologic parameters using preoperative and postoperative x-ray images.
Results
We successfully inserted dual direction expandable cages during biportal endoscopic TLIF. There was no significant subsidence or collapse of the expandable cages during the 6-month follow-up period. Lumbar lordosis and disc height were significantly increased after surgery. ODI and VAS scores were significantly improved at 6 months after surgery.
Conclusion
In this report, we describe the first use of a dual direction expandable interbody TLIF cage that expands in both width and height in biportal endoscopic TLIF surgery. Early clinical and radiographic outcomes of this TLIF technique may be favorable in early 6-month follow-up.

Citations

Citations to this article as recorded by  Crossref logo
  • Evidence-Based Guidelines for the Surgical Management of Degenerative Lumbar Spondylolisthesis
    Harrison J. Howell, Nathan J. Winans, Dean Chou, Andrew K. Chan
    Neurosurgery Clinics of North America.2026; 37(1): 1.     CrossRef
  • Meta-Analysis of Complications in Minimally Invasive Spine Surgery (2013–2024)
    Sean Inzerillo, Eesha Gurav, Chibuikem A. Ikwuegbuenyi, Noah Willett, Mousa Hamad, Ibrahim Hussain, Alan Hernández-Hernández, Galal Elsayed, Roger Härtl, Osama Kashlan
    Spine.2026; 51(3): E47.     CrossRef
  • Sagittal Alignment and Clinical Outcomes After Biportal Endoscopic Transforaminal Lumbar Interbody Fusion Using a Single Expandable Cage: One Year Follow-up
    Sub-Ri Park, Namhoo Kim, Ji-Won Kwon, Kyung-Soo Suk, Hak-Sun Kim, Seong-Hwan Moon, Si-Young Park, Byung Ho Lee, Jae-Won Shin, Jin-Oh Park
    World Neurosurgery.2026; 205: 124698.     CrossRef
  • Clinical and radiologic outcomes of expandable versus static cages in biportal endoscopic TLIF: focus on endplate injury and subsidence
    Tae Hoon Kang, Geumho Lee, Byungjun Kang, Jeongwoon Han, Hyun-jin Park, Minjoon Cho, Jae Hyup Lee
    Journal of Orthopaedic Surgery and Research.2026;[Epub]     CrossRef
  • Posterior and Transforaminal Lumbar Interbody Fusion
    Arpan A. Patel, Shaarada Srivatsa, Mark A. Davison, Michael P. Steinmetz
    Neurosurgery Clinics of North America.2025; 36(1): 11.     CrossRef
  • An Analysis of the Complication Reports of Expandable Lumbar Interbody Cages in the Food and Drug Administration Manufacturer and User Facility Device Experience Database
    William ElNemer, Andrew Kim, Juan Silva-Aponte, Micheal Raad, Tej Azad, Wesley M. Durand, Hamid Hassanzadeh, Khaled Kebaish, Amit Jain
    Orthopedics.2025;[Epub]     CrossRef
  • Expandable interbody cages for lumbar spinal fusion: a systematic review
    Daniel Orr, Ron Anderson, Anna Jensen, Tyler Peterson, John Edwards, Anton E. Bowden
    The Spine Journal.2025; 25(8): 1773.     CrossRef
  • Safety and Utility of Bilateral-contralateral Decompression for Adjacent Segment Stenosis After Lumbar Interbody Fusion Using Unilateral Biportal Endoscopy
    Dong Hyun Lee, Choon Keun Park, Jae-Won Jang, Dong-Geun Lee
    Clinical Spine Surgery.2025; 38(10): E488.     CrossRef
  • Percutaneous Endoscopic Transforaminal Lumbar Interbody Fusion with an Expandable Cage for the Treatment of Degenerative Lumbar Spinal Stenosis with Instability
    Xiaokang Cheng, Qiaoling Chen, Bin Chen, Jiaguang Tang
    World Neurosurgery.2025; 197: 123876.     CrossRef
  • Novel Design of Expandable Spinal Cage for Efficient Lumbar Spine Fusion Operation
    Chanwoo Park, Than Trong Khanh Dat, Sung-Jun Park, Dong-Sik Chae, Sung Hoon Choi, Jonghun Yoon
    Applied Sciences.2025; 15(11): 6323.     CrossRef
  • History of endoscopic spine surgery: where did it all begin? Development of indications and techniques
    Dong Hwa Heo, Hyeun Sung Kim, Yoon Ha Whang, Dong Chan Lee, Kangtaek Lim
    The Spine Journal.2025;[Epub]     CrossRef
  • Advancements in biomaterials and bioactive solutions for lumbar spine fusion cages: Current trends and future perspectives
    Iulian Antoniac, Veronica Manescu (Paltanea), Gheorghe Paltanea, Aurora Antoniac, Marco Fosca, Dan Laptoiu, Julietta V. Rau
    Bioactive Materials.2025; 53: 656.     CrossRef
  • Clinical outcome and complications comparison between expandable and static cages in open TLIF surgery: A 2-year retrospective study
    Ta-Wei Lai, Po-Ming Chen, Chi-Huan Li, Cheng-Jung Chan, Po-Cheng Cheng, Chun-Hsien Huang, Li-Ching Kuo, Ming-Chou Ku
    Medicine.2025; 104(34): e44042.     CrossRef
  • Expandable Cage in Minimally Invasive Transforaminal Lumbar Interbody Fusion: Comparative Data with Static Cage from a Single Institution and a Single Surgeon
    Dongkyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Jeong Yoon Park
    World Neurosurgery.2025; 202: 124428.     CrossRef
  • Biportal Endoscopic Lumbar Interbody Fusion Using the Oblique Lumbar Interbody Fusion Cage: Technical Note and Case Illustration
    Tran Vu Hoang Duong, Phan Quang Son, Le Tan Bao, Luc Dinh Phuong, Phan Dinh Thanh
    Journal of Minimally Invasive Spine Surgery and Technique.2025; 10(2): 303.     CrossRef
  • Comparative Clinical and Radiological Outcomes of Banana-Shaped Versus Straight Cages in Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: A Retrospective Cohort Study
    Nguyen Ngoc Thoi, Nguyen Le Hoang Tuan, Le Tuong Vien, Nguyen Thanh Nhan, Hoang Nguyen Anh Tuan, Nguyen Van Thanh, Tran Nguyen Phuong, Bui Hong Thien Khanh
    Journal of Minimally Invasive Spine Surgery and Technique.2025; 10(2): 172.     CrossRef
  • Novel Unilateral Biportal Endoscopy-Assisted Lumbar Fusion With Dual Hybrid Cage Insertion: A Technical Note With Case Presentation
    Jisoo Ha, Kuldeep Bansal, Chang-Wook Kim, Do-Hyoung Kim, Shreenidhi Kulkarni, Hee-Don Han
    Journal of Minimally Invasive Spine Surgery and Technique.2025; 10(2): 230.     CrossRef
  • Improved Clinical and Radiological Outcomes with Double-Cage Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: A Comparative CT-Based Study
    Yu-Hao Huang, Jwo-Luen Pao
    Diagnostics.2025; 15(20): 2652.     CrossRef
  • Therapeutic Approaches for Enhancing Spinal Fusion in Low Back Pain: A Review With a Focus on the Elderly
    Shuimu Chen, Zhen Li, Sebastian F. Bigdon, Sonja Häckel, Christoph E. Albers, Benjamin Gantenbein
    JOR SPINE.2025;[Epub]     CrossRef
  • A Comparison of 2 Cage Sizes in Biportal Endoscopic Transforaminal Lumbar Interbody Fusion
    Ju-Eun Kim, Hyunwoo Kim, Eugene J. Park, Daniel K. Park
    Clinical Spine Surgery.2024; 37(10): E464.     CrossRef
  • Expandable Cages for Lumbar Interbody Fusion: A Narrative Review
    Soo-Bin Lee, Jonghun Yoon, Sung-Jun Park, Dong-Sik Chae
    Journal of Clinical Medicine.2024; 13(10): 2889.     CrossRef
  • A novel endoscope-port unit for lumbar microendoscopic surgery: a single-center case series review
    Vicente de Paulo Martins Coelho Junior, Anthony M. Alvarado, Richard G. Fessler
    Neurosurgical Review.2024;[Epub]     CrossRef
  • New Paradigm of Endoscopic Spine Surgery: Unilateral Biportal Endoscopic Spinal Surgery
    Dong Hwa Heo, Jin Hwa Eum
    Journal of Minimally Invasive Spine Surgery and Technique.2024; 9(2): 81.     CrossRef
  • Comparative Outcomes of Biportal Endoscopic Decompression, Conventional Subtotal Laminectomy, and Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar Central Stenosis
    Mu Ha Lee, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Dong Kyu Chin, Keun Su Kim, Jeong-Yoon Park
    Neurospine.2024; 21(4): 1178.     CrossRef
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Pearls and Pitfalls of Oblique Lateral Interbody Fusion: A Comprehensive Narrative Review
Neurospine. 2022;19(1):163-176.   Published online March 31, 2022
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Pearls and Pitfalls of Oblique Lateral Interbody Fusion: A Comprehensive Narrative Review
Neurospine. 2022;19(1):163-176.   Published online March 31, 2022
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Lumbar degenerative disease is a common problem in an aging society. Oblique lateral interbody fusion (OLIF) is a minimally invasive surgical (MIS) technique that utilizes a retroperitoneal antepsoas corridor to treat lumbar degenerative disease. OLIF has theoretical advantages over other lumbar fusion techniques, such as a lower risk of lumbar plexus injury than direct lateral interbody fusion (DLIF). Previous studies have reported favorable clinical and radiological outcomes of OLIF in various lumbar degenerative diseases. The use of OLIF is increasing, and evidence on OLIF is growing in the literature. The indications for OLIF are also expanding with the help of recent technical developments, including stereotactic navigation systems and robotics. In this review, we present current evidence on OLIF for the treatment of lumbar degenerative disease, focusing on the expansion of surgical indications and recent advancements in the OLIF procedure.

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Spine and Spinal Cord Tumors DSPN-Neurospine Special Issue

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Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations
Neurospine. 2022;19(1):1-12.   Published online March 31, 2022
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Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations
Neurospine. 2022;19(1):1-12.   Published online March 31, 2022
Close
Bleeding in spine surgery is a common occurrence but when bleeding is uncontrolled the consequences can be severe due to the potential for spinal cord compression and damage to the central nervous system. There are many factors that influence bleeding during spine surgery including patient factors and those related to the type of surgery and the surgical approach to bleeding. There are a range of methods that can be employed to both reduce the risk of bleeding and achieve hemostasis, one of which is the adjunct use of hemostatic agents. Hemostatic agents are available in a variety of forms and materials and with considerable variation in cost, but specific evidence to support their use in spine surgery is sparse. A literature review was conducted to identify the pre-, peri-, and postsurgical considerations around bleeding in spine surgery. The review generated a set of recommendations that were discussed and ratified by a wider expert group of spine surgeons. The results are intended to provide a practical guide to the selection of hemostats for specific bleeding situations that may be encountered in spine surgery.

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Change in Patient-Reported Outcome Measures as Predictors of Revision Lumbar Decompression Procedures
Neurospine. 2021;18(4):863-870.   Published online December 31, 2021
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Change in Patient-Reported Outcome Measures as Predictors of Revision Lumbar Decompression Procedures
Neurospine. 2021;18(4):863-870.   Published online December 31, 2021
Close
Objective
To assess change in Patient-Reported Outcome Measures (PROM) as predictors for revision lumbar decompression (LD).
Methods
Patients who underwent primary, single or multilevel LD were retrospectively reviewed. Patients were categorized according to whether or not they underwent revision LD within 2 years of the primary procedure. Visual analogue scale (VAS), Oswestry Disability Index (ODI), 12-item Short Form Health Survey and 12-item Veterans RAND physical component score (SF-12 PCS and VR-12 PCS), and Patient-Reported Outcome Measurement Information System physical function (PROMIS-PF) were recorded. Delta PROM scores were evaluated for differences between groups and as a risk factor for a revision LD.
Results
The study included 135 patients, 91 undergoing a primary procedure only and 44 undergoing a primary and revision procedure. Matched patients did not demonstrate any significant differences in demographics or perioperative characteristics. Patients who underwent a revision had a mean time to revision of 7.4 ± 5.7 months. Primary cohort significantly improved for all PROMs (all p < 0.05), while the primary plus revision cohort significantly improved for VAS back, ODI, and PROMIS-PF (all p < 0.05). However, cohorts differed in VAS back and PROMIS-PF (p < 0.05). Delta PROMs were not a significant risk factor for revision except at 6 months for PROMIS-PF (p = 0.024).
Conclusion
LD has been associated with reliable outcomes, but early identification of patients at risk for revision is critical. This study suggests that tools such as PROMIS-PF may serve a role in predicting who is at risk and the 6-month follow-up period may be valuable for counseling patients who are not experiencing improvement.

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  • Use of the Patient-Reported Outcomes Measurement Information System (PROMIS) Outcome Measures in Lumbar Decompression Surgery: A Systematic Review
    Harneet K Cheema, Manraj S Cheema, James Gomes
    Cureus.2026;[Epub]     CrossRef
  • Association between spinal manipulative therapy and lumbar spine reoperation after discectomy: a retrospective cohort study
    Robert J. Trager, Jordan A. Gliedt, Collin M. Labak, Clinton J. Daniels, Jeffery A. Dusek
    BMC Musculoskeletal Disorders.2024;[Epub]     CrossRef
  • Screening patients requiring secondary lumbar surgery for degenerative lumbar spine diseases: a nationwide sample cohort study
    Hangeul Park, Juhee Lee, Yunhee Choi, Jun-Hoe Kim, Sum Kim, Young-Rak Kim, Chang-Hyun Lee, Sung Bae Park, Kyoung-Tae Kim, John M. Rhee, Chi Heon Kim
    Scientific Reports.2024;[Epub]     CrossRef
  • Perioperative Predictors in Patients Undergoing Lateral Lumbar Interbody Fusion for Minimum Clinically Important Difference Achievement
    James W. Nie, Timothy J. Hartman, Omolabake O. Oyetayo, Keith R. MacGregor, Eileen Zheng, Vincent P. Federico, Dustin H. Massel, Arash J. Sayari, Kern Singh
    World Neurosurgery.2023; 175: e914.     CrossRef
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Unilateral Posterior Surgery for Severe Osteoporotic Vertebrae Fractures’ Sequelae in Geriatric Population: Minimum 5-Year Results of 109 Patients
Neurospine. 2021;18(2):319-327.   Published online March 4, 2021
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Unilateral Posterior Surgery for Severe Osteoporotic Vertebrae Fractures’ Sequelae in Geriatric Population: Minimum 5-Year Results of 109 Patients
Neurospine. 2021;18(2):319-327.   Published online March 4, 2021
Close
Objective
This study aimed to evaluate the efficacy and safety of modified posterior vertebral column resection (PVCR) combined with anterior column restoration in elderly patients presenting with thoracic or thoracolumbar osteoporotic fractures with spinal cord compression and severe pain.
Methods
One hundred nine patients with one level thoracolumbar osteoporotic fracture and at least 5 years of follow-up were included. They underwent posterior instrumentation performed with polymethymetachrylate augmented pedicle screws. A modified PVCR (unilateral costotransversectomy+hemilaminectomy) combined with the insertion of an expandable titanium cage for anterior column restoration was undertaken. Patients were evaluated clinically and radiographically.
Results
Patients had a mean age of 74.1 and a follow-up duration of 92.3 months. Mean duration of operations, hospital stays, and mean loss of blood were 172.3 minutes, 4.3 days, and 205.4 mL. All of the patients were mobilized immediately after surgery. The mean preoperative local kyphosis angle improved from 39.3° to 4.7° at the last follow-up (p = 0.003). Patients preoperative mean visual analogue score, Japanese Orthopaedic Association, and Oswestry Disability Index scores improved from 7.7/8.6/76.3 to 1.6/26.1/17.4 (p < 0.001 for all), respectively. The average 36-item Short-Form survey physical component summary/mental component summary scores at the last follow-up were 55.1/56.8. A dural tear was detected intraoperatively in 1 patient and repaired immediately.
Conclusion
Subtotal PVCR combined with the insertion of an expandable titanium cage was detected as a safe and effective method for osteoporotic vertebrae fractures’ sequelae in the older population involving spinal cord compression by enabling the decompression of the spinal canal and reconstruction of the resected segment, resulting in significant improvement in clinical and radiographic outcomes.

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  • Outcomes of Kyphoplasty Versus Pedicle Screw Fixation for Osteoporotic Vertebral Compression Fractures: A Comparative Analysis
    Natalie Slosar, Moustafa Hadi, Nachiket M. Deshpande, Katherine Holste, Noojan J. Kazemi, Yamaan S. Saadeh
    World Neurosurgery.2026; 205: 124592.     CrossRef
  • Effectiveness of Posterior Long-Segment Fixation for Thoracolumbar Osteoporotic Compression Fractures: A Retrospective Study
    Jong-Hwan Hong, Jong-Hoon Jung, Ji-Ho Jung, Moon-Soo Han, Jung-Kil Lee
    World Neurosurgery.2025; 194: 123433.     CrossRef
  • Comparative analysis of surgical treatment results for osteoporotic burst fractures of thoracolumbar vertebral bodies
    V. D. Sinyavin, V. V. Rerikh
    Genij Ortopedii.2024; 30(4): 542.     CrossRef
  • Fatty Infiltration of Multifidus Muscles: An Easily Overlooked Risk Factor for the Severity of Osteoporotic Vertebral Fractures
    Wuyan Xu, Xiaowen Liu, Li Wu, Shaohua Liang, Ye Zhang, Junbing Huang, Xuwen Zeng, Siming Li, Fan Xu, Yuchao Xiong
    Orthopaedic Surgery.2024; 16(3): 585.     CrossRef
  • Modified pedicle subtraction osteotomy for osteoporotic vertebral compression fractures: a retrospective study of 104 patients
    Junyu Li, Jiahao Zhang, Siming Xian, Wenbin Bai, Yihao Liu, Zhuoran Sun, Yongqiang Wang, Miao Yu, Weishi Li, Yan Zeng, Yun Tian
    European Spine Journal.2024; 33(8): 3275.     CrossRef
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    The Spine Journal.2023; 23(11): 1586.     CrossRef
  • Open Surgical Treatments of Osteoporotic Vertebral Compression Fractures
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    Orthopaedic Surgery.2023; 15(11): 2743.     CrossRef
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  • Comparison of clinical effectiveness of fenestrated and conventional pedicle screws in patients undergoing spinal surgery: a systematic review and meta-analysis
    Mitsuru Yagi, Mami Ogiri, Chantal E. Holy, Anh Bourcet
    Expert Review of Medical Devices.2021; 18(10): 995.     CrossRef
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Methods and Early Clinical Results of Percutaneous Lumbar Interbody Fusion
Neurospine. 2020;17(4):910-920.   Published online December 31, 2020
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Methods and Early Clinical Results of Percutaneous Lumbar Interbody Fusion
Neurospine. 2020;17(4):910-920.   Published online December 31, 2020
Close
Objective
Percutaneous lumbar interbody fusion (PELIF) is a procedure that includes the use of new devices, which allow minimally invasive diskectomy under the percutaneous full-endoscopic guidance and safe percutaneous insertion of a standard-sized cage. This procedure can be applied to severe disk degeneration, spondylolisthesis, and all lumbar intervertebral levels including the L5–S1 level. We report the methods and the clinical outcomes of this procedure.
Methods
Percutaneous diskectomy was performed with an outer sheath cutter and other devices. A cage was inserted with an L-shaped retract-slider. Hybrid facet screw fixation was performed for severe disk degeneration without spondylolisthesis. Conventional percutaneous pedicle screw fixation was performed for spondylolisthesis. The subjects consisted of 21 patients, who underwent PELIF and were followed up for 1 year or longer.
Results
No complications related to cage insertion were detected. The mean visual analogue scale scores were improved from 6.1 to 1.9 for lower back pain in severe disc degeneration cases without spondylolisthesis, and from 7.6 to 1.0 for lower extremity symptoms in spondylolisthesis cases.
Conclusion
The clinical outcomes were favorable. PELIF was found to be a minimally invasive method that did not compromise safety and efficiency. PELIF is a possible therapeutic option that should be considered for not only spondylolisthesis at various intervertebral levels but also for severe disk degeneration because of its minimal invasiveness.

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  • A Novel Full-percutaneous Trans-Kambin Lumbar Interbody Fusion (pTLIF) With a Large-footprint Interbody Cage
    Christian Morgenstern, Rudolf Morgenstern
    Clinical Spine Surgery.2026; 39(3): 100.     CrossRef
  • Exiting nerve root injury during full-endoscopic trans-Kambin’s triangle lumbar interbody fusion (FE-KLIF) and how to avoid it:a multicenter study
    Kozaburo Mizutani, Masatoshi Morimoto, Seiji Yamaya, Kiyoshi Yagi, Kazuya Kishima, Takashi Inokuchi, Shutaro Fujimoto, Takahiro Ogawa, Tomoya Terai, Nobutoshi Takamatsu, Kazuta Yamashita, Fumitake Tezuka, Kosuke Sugiura, Masashi Kumon, Yutaro Kanda, Saori
    The Journal of Medical Investigation.2026; 73(1.2): 26.     CrossRef
  • Anterior Lumbar Interbody Fusion (ALIF) Versus Full-Endoscopic/Percutaneous TLIF With a Large-Footprint Interbody Cage: A Comparative Observational Study
    Christian Morgenstern, Francisco Nogueras, Geoffrey Delbos, Rudolf Morgenstern
    Global Spine Journal.2025; 15(6): 2910.     CrossRef
  • Full-Percutaneous Trans-Kambin Lumbar Interbody Fusion With a Large-Footprint Interbody Cage
    Christian Morgenstern, Rudolf Morgenstern
    Global Spine Journal.2025; 15(7): 3101.     CrossRef
  • Advances in minimally invasive surgical techniques for lumbar disc herniation: a comprehensive review
    Weiqiang Lan, Hanbing Cui, Di Zhou, Xiao Xiao, Hongbo Xiong
    Frontiers in Surgery.2025;[Epub]     CrossRef
  • Optimizing Disc and Cartilage Endplate Preparation in Full-Endoscopic Lumbar Interbody Fusion: An In-Depth Exploration of Surgical Instruments with a Technique Note and Narrative Review
    Kai-Ting Chien, Hsiang-Wei Feng, Ting-Kuo Chang, Yueh-Ching Liu, Lei-Po Chen, Yu-Ching Huang, Yan-Shiang Lian, Jian-You Li
    World Neurosurgery.2024; 189: 228.     CrossRef
  • Cost-utility analysis of endoscopic lumbar discectomy following a uniform clinical pathway in the Korean national health insurance system
    Chi Heon Kim, Yunhee Choi, Chun Kee Chung, Seung Heon Yang, Chang-Hyun Lee, Sung Bae Park, Keewon Kim, Sun Gun Chung, Sathish Muthu
    PLOS ONE.2023; 18(6): e0287092.     CrossRef
  • Minimization of lumbar interbody fusion by percutaneous full-endoscopic lumbar interbody fusion (PELIF), and its minimally invasiveness comparison with minimally invasive surgery-transforaminal lumbar interbody fusion (MIS-TLIF)
    Kenyu Ito, Zenya Ito, Shu Nakamura, Fujio Ito, Motohide Shibayama, Yasushi Miura
    Interdisciplinary Neurosurgery.2023; 34: 101794.     CrossRef
  • Systematic Review: Applications of Intraoperative Ultrasonography in Spinal Surgery
    Madhav R. Patel, Kevin C. Jacob, Alexander W. Parsons, Frank A. Chavez, Max A. Ribot, Mohammed A. Munim, Nisheka N. Vanjani, Hanna Pawlowski, Michael C. Prabhu, Kern Singh
    World Neurosurgery.2022; 164: e45.     CrossRef
  • SURGICAL TECHNIQUE AND CLINICAL BENEFITS IN FULL-ENDOSCOPIC TRANS-KAMBIN TRIANGLE LUMBAR INTERBODY FUSION (KLIF): A REVIEW
    Koichi Sairyo, Masatoshi Morimoto, Kazuta Yamashita, Fumitake Tezuka, Kosuke Sugiura, Makoto Takeuchi, Shunsuke Tamaki, Takuma Abe, Kohei Ota, Shinya Nakagawa, Takashi Inokuchi, Junzo Fujitani
    Journal of Musculoskeletal Research.2022;[Epub]     CrossRef
  • Analysis of curative effect of percutaneous coaxial large channel endoscopic lumbar interbody fusion in the treatment of degenerative lumbar spinal stenosis
    Pin Feng, Qingquan Kong, Bin Zhang, Junlin Liu, Junsong Ma, Yuan Hu
    Frontiers in Surgery.2022;[Epub]     CrossRef
  • Kambin's triangle-related data based on magnetic resonance neurography and its role in percutaneous transforaminal endoscopic lumbar interbody fusion
    Tianqi Li, Gang Wu, Yongle Dong, Zhiwei Song, Haijun Li
    Journal of Orthopaedic Surgery and Research.2022;[Epub]     CrossRef
  • Commentary on “Endoscopic Transforaminal Lumbar Interbody Fusion – Technical note”
    Junseok Bae
    Journal of Spinal Surgery.2022; 9(4): 240.     CrossRef
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    Koichi Sairyo, Masatoshi Morimoto, Kazuta Yamashita, Fumitake Tezuka, Kosuke Sugiura, Makoto Takeuchi, Kiyoshi Yagi, Kazuya Kishima, Junzo Fujitani, Yoichiro Takata, Toshinori Sakai, Toru Maeda
    Journal of Minimally Invasive Spine Surgery and Technique.2021; 6(Suppl 1): S123.     CrossRef
  • 8,641 View
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Chronic Opioid Use Following Lumbar Discectomy: Prevalence, Risk Factors, and Current Trends in the United States
Neurospine. 2020;17(4):879-887.   Published online December 31, 2020
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Chronic Opioid Use Following Lumbar Discectomy: Prevalence, Risk Factors, and Current Trends in the United States
Neurospine. 2020;17(4):879-887.   Published online December 31, 2020
Close
Objective
Lumbar discectomy is commonly performed for symptomatic lumbar disc herniation. We aimed to examine prescribing patterns and risk factors for chronic opioid use following lumbar discectomy.
Methods
Using a private insurance claims database, patients were identified who underwent primary lumbar discectomy from 2010–2015 and had 1-year of continuous enrollment postoperatively. Patients were excluded with spinal fusion. The strength of opioid prescriptions was quantified using morphine milligram equivalents daily (MMED). Univariate and multivariate logistic regression models were built to examine risk factors associated with chronic postoperative opioid use.
Results
A total of 5,315 patients were included in the study (mean age, 59 years; 50% female). 1,198 of patients (23%) used chronic opioids postoperatively. Chronic opioid use declined significantly from 27% in 2010 to 17% in 2015, p < 0.001. In addition, there were significantly fewer patients receiving high and very high-dose opioid prescriptions from 2010–2015, p < 0.001. The median duration that patients used opioids postoperatively was 211 days in 2010 (interquartile range [IQR], 29–356 days), and decreased significantly to 44 days (IQR, 10–294 days) in 2015. The strongest factors associated with chronic opioid use were preoperative opioid use (odds ratio [OR], 4.0), drug abuse (OR, 2.6), depression (OR, 1.6), surgery in the west (OR, 1.6) or south (OR, 1.6), anxiety (OR, 1.5), or 30-day readmission (OR, 1.4).
Conclusion
Chronic opioid use following primary lumbar discectomy has declined from 2010–2015. A variety of factors are associated with chronic opioid use. Preoperative recognition of some of these risk factors may aid in perioperative management and counseling.

Citations

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  • Combined pulse radiofrequency and selective nerve root block for lumbar disc herniation-related neuropathic pain: a retrospective cohort study
    Jie Chen, Hui Lu, Xinchao Jiang, Yi Song, Bin Qian, Mei Fang, Jianxue Qian, Cailin Wang
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Opioid Prescribing Trends Following Lumbar Discectomy
    Albert L. Rancu, Michael J. Gouzoulis, Adam D. Winter, Beatrice M. Katsnelson, Jeremy K. Ansah-Twum, Jonathan N. Grauer
    Journal of the American Academy of Orthopaedic Surgeons.2025; 33(18): 1054.     CrossRef
  • Trends of opioid use following anterior cervical discectomy and fusion: A 10-year longitudinal study of the Veterans Health Administration
    Andrew M. Gabig, Paymon G. Rezaii, Sean C. Clark, Bela P. Delvadia, Olivia C. Lee, William F. Sherman, Mathew Cyriac
    North American Spine Society Journal (NASSJ).2025; 22: 100595.     CrossRef
  • Opioid-use disorder and reported pain after spine surgery: Risk-group patterns in cognitive-appraisal processes in a longitudinal cohort study
    Carolyn E Schwartz, Katrina Borowiec, Bruce D Rapkin, Joel A Finkelstein, Tai Sutherland, Olivia B Caan, Richard L Skolasky
    North American Spine Society Journal (NASSJ).2025; 22: 100605.     CrossRef
  • Decreasing utilization of opioids and prescription nonopioids following lumbar discectomy
    Philip P. Ratnasamy, Gwyneth C. Maloy, John Slevin, Arya G. Varthi, Jonathan N. Grauer
    North American Spine Society Journal (NASSJ).2025; 24: 100793.     CrossRef
  • The Impact of Preoperative Nicotine Use in the Development of Opioid Use Disorder Following Lumbar Disc Discectomy Procedures: A National Database Study
    Jinpyo Hong, Andrew Kim, Zachary Freedman, Shoshanna Jadoonanan, David R Hallan, Elias Rizk, John P Kelleher
    Cureus.2025;[Epub]     CrossRef
  • Association Between Early Surgery and Postoperative Opioid Use in Patients With Lumbar Disc Herniation: A Propensity Score-Matching Analysis Using an Administrative Claims Database in Japan
    Akira Honda, Yoichi Iizuka, Mieda Tokue, Eiji Takasawa, Sho Ishiwata, Yusuke Tomomatsu, Shunsuke Ito, Kazuhiro Inomata, Akira Okada, Hiroki Matsui, Hideo Yasunaga, Hirotaka Chikuda
    Global Spine Journal.2024; 14(6): 1738.     CrossRef
  • A study on the 10-year trend of surgeries performed for lumbar disc herniation and comparative analysis of prescribed opioid analgesics and hospitalization duration: 2010–2019 HIRA NPS Data
    Sang Yoon Kim, Yu-Cheol Lim, Byung-Kwan Seo, Dongwoo Nam, In-Hyuk Ha, Ye-Seul Lee, Yoon Jae Lee
    BMC Musculoskeletal Disorders.2024;[Epub]     CrossRef
  • Biportal Endoscopic Spine Surgery for Lumbar Laminectomy and Diskectomy: Postoperative Outcomes and Surgical Learning Curve, a Single US Surgeon's Experience
    Matthew Easthardt, Philip Zakko, Ali Jawad, Maximillian Lee, Daniel Park
    JAAOS: Global Research and Reviews.2024;[Epub]     CrossRef
  • The Current Status of Awake Endoscopic Surgery: A Systematic Review and Meta-Analysis
    Caroline N. Jadczak, Nisheka N. Vanjani, Hanna. Pawlowski, Elliot D.K. Cha, Conor P. Lynch, Michael C. Prabhu, Timothy J. Hartman, James W. Nie, Keith R. MacGregor, Eileen. Zheng, Omolabake O. Oyetayo, Kern. Singh
    World Neurosurgery.2023; 180: e198.     CrossRef
  • Endogenous opiates and behavior: 2020
    Richard J. Bodnar
    Peptides.2022; 151: 170752.     CrossRef
  • 8,804 View
  • 121 Download
  • 10 Web of Science
  • 11 Crossref

Case Reports

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Monostotic Paget Disease of the Lumbar Vertebrae: A Pathological Mimicker
Neurospine. 2018;15(2):182-186.   Published online June 19, 2018
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Monostotic Paget Disease of the Lumbar Vertebrae: A Pathological Mimicker
Neurospine. 2018;15(2):182-186.   Published online June 19, 2018
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Paget disease is a metabolic disorder involving abnormal bone turnover that consists of 3 phases: the initial lytic phase, the intermediate mixed phase, and the chronic sclerotic phase. Paget disease mostly presents as polyostotic or monostotic lesions of the spine, and is rare on the Indian subcontinent. We present a case of isolated Paget disease of the lumbar third vertebra, which was confirmed only at biopsy. The patient presented with chronic low backache with a developing neurological deficit. We managed the patient with posterior spinal stabilisation, using pedicular screws and vertebroplasty of the collapsed vertebrae to regain the height. Upon the diagnosis of Paget disease, the patient was treated with calcitonin and bisphosphonates for 3 months, along with regular monitoring of alkaline phosphatase levels. Through this case, we hope to emphasize that Paget disease should be considered in the differential diagnosis of lytic lesions. Additionally, the alkaline phosphatase level in this patient was high-normal, which was an aspect of the role of Paget disease as a mimicker. Confirmatory biopsy is mandatory in all lesions.

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  • Spinal manifestations of Paget's disease: Case presentation and systematic review
    Abdullah T. Eissa, Karlo M. Pedro, Andrew F. Gao, Michael G. Fehlings
    Brain and Spine.2025; 5: 105889.     CrossRef
  • Monostotic humeral Paget's disease
    Jaahnavi Konidala, Rishi Raj
    BMJ Case Reports.2022; 15(10): e252655.     CrossRef
  • Is Paget Disease of Bone more Common in South India? Clinical Characteristics, Therapeutic Outcome and follow-up of 66 Patients from Tamil Nadu
    Adlyne R. Asirvatham, Subramanian Kannan, Shriraam Mahadevan, Karthik Balachandran, Geethalakshmi Sampathkumar, Dhalapathy Sadacharan, Satish K. Balasubramanian
    Indian Journal of Endocrinology and Metabolism.2020; 24(4): 306.     CrossRef
  • 12,343 View
  • 170 Download
  • 4 Web of Science
  • 3 Crossref

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Postlaminectomy Bilateral Lumbar Intraspinal Synovial Cysts
Korean J Spine. 2016;13(3):157-159.   Published online September 30, 2016
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Postlaminectomy Bilateral Lumbar Intraspinal Synovial Cysts
Korean J Spine. 2016;13(3):157-159.   Published online September 30, 2016
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Lumbar intraspinal synovial cysts are included in the difference diagnosis of lumbar radiculopathy. Developing imaging modalities has result in increased reporting about these lesions. However, the case of bilateral new lumbar intraspinal synovial cysts after laminectomy has been rarely reported. We report of a rare case with bilateral lumbar intraspinal synovial cysts after laminectomy, requiring surgical excision.

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  • A challenge diagnosis of lumbar synovial facet cyst. A case report
    Zayed Filali, Amine Briki, Souad Ferjani, Yassine Aloui, Oubaidallah Moulahi, Naoufel Haddad
    International Journal of Surgery Case Reports.2024;[Epub]     CrossRef
  • Bilateral ganglion cysts at L4/5 causing central canal stenosis and producing sciatica and neurogenic claudication: a case report
    CM Allison, G Bonanos, A Varma
    The Annals of The Royal College of Surgeons of England.2022; 104(2): e41.     CrossRef
  • Transforaminal Epiduroscopic Laser Ablation for Removal of a Postlaminectomy Synovial Cyst: A Case Report
    Hee Yong Kang, So Yeon Kim, Chung Hun Lee, Sung Wook Park
    Medicina.2020; 56(5): 209.     CrossRef
  • Juxta Facet Cyst Associated with Lumbar Laminectomy
    Yoshiyuki Takaishi, Hirofumi Iwahashi, Naoto Nakamura, Takeshi Kondoh, Atsushi Uyama, Atsushi Arai
    Spinal Surgery.2018; 32(3): 311.     CrossRef
  • Hemorrhagic Lumbar Synovial Cyst after Microscopic Discectomy
    Hak Sung Kim, Seok Won Kim
    Korean Journal of Spine.2017; 14(3): 93.     CrossRef
  • 9,777 View
  • 110 Download
  • 5 Crossref

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Multiple Intradural Disc Herniations Masquerading as Intradural Extramedullary Tumors: A Case Report and Review of the Literature
Korean J Spine. 2016;13(1):30-32.   Published online March 31, 2016
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Multiple Intradural Disc Herniations Masquerading as Intradural Extramedullary Tumors: A Case Report and Review of the Literature
Korean J Spine. 2016;13(1):30-32.   Published online March 31, 2016
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Intradural disc herniation is a very rare condition, and multiple intradural disc herniations have not been reported to date. The latter may be confused with intradural extramedullary (IDEM) spinal tumors. Here, we report a case of multiple intradural disc herniations masquerading as multiple IDEM tumors and review the relevant literature. We retrospectively reviewed the patient's medical chart, reviewed the intraoperative microscopic findings, and reviewed of PubMed articles on intradural disc herniation. The masses considered to be IDEM tumors were confirmed to be multiple intradural disc herniations. A nonenhancing mass was found to have migrated along the intra-arachnoid space. Two enhancing masses could not migrate because of adhesion and showed peripheral neovascularization. We report an extremely rare case of multiple intradural lumbar disc herniations showing diverse enhancing patterns and masquerading as multiple IDEM tumors. In case of multiple enhancing IDEM masses suspected preoperatively, surgeons should consider the possibility of intradural disc herniation.

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  • Percutaneous endoscopic interlaminar discectomy for posterior epidural migration of a lumbar disc fragment case report
    Xiao-Long Zhu, Yong-Jun Hua
    Journal of Orthopaedic Reports.2026; 5(1): 100658.     CrossRef
  • Revisión sistemática de la hernia discal intradural: perspectiva de un neurocirujano
    Alberto Morello, Enrico Lo Bue, Ayoub Saaid, Stefano Colonna, Alessandro Pesaresi, Federica Bellino, Marco Ajello, Alessandro Fiumefreddo, Diego Garbossa, Fabio Cofano
    Neurocirugía.2026; 37(3): 500743.     CrossRef
  • A systematic review of intradural disk herniation: A neurosurgeon's perspective
    Alberto Morello, Enrico Lo Bue, Ayoub Saaid, Stefano Colonna, Alessandro Pesaresi, Federica Bellino, Marco Ajello, Alessandro Fiumefreddo, Diego Garbossa, Fabio Cofano
    Neurocirugía (English Edition).2025; : 500743.     CrossRef
  • Imaging of Sequestered Lumbar Discs
    Gangwon Jeong, Heecheol Park, Sun Joo Lee, Dae-Hyun Park, Sung Hwa Paeng, Eugene Lee
    Journal of the Korean Society of Radiology.2024; 85(1): 3.     CrossRef
  • Intradural sequestration of lumbar disc herniation with cranial migration: a case report
    Grigoriy Yu. Evzikov, Mikhail G. Bashlachev, Maksim I. Gaydash
    Sechenov Medical Journal.2024; 15(4): 51.     CrossRef
  • Intradural lumbar disc herniation: A case report and literature review
    Cheng-Hsin Cheng, MD, PhD. Che-Chao Chang, Hung-Lin Lin, Hao-Yu Chuang, Ruey-Mo Lin, Ning-Ping Foo
    Heliyon.2022; 8(12): e12257.     CrossRef
  • A Case of Lumbar Disc Herniation Penetrating the Ventral and Dorsal Dura Mater with Notable Osteophytes
    Kiminori Sakurai, Kousei Oshima, Manabu Niimura, Kaiji Ota, Naoto Tsuchiya
    Spinal Surgery.2022; 36(3): 277.     CrossRef
  • Intradural lumbar disc herniation: illustrative case
    Rivka Chinyere Ihejirika, Yixuan Tong, Karan Patel, Themistocles Protopsaltis
    Journal of Neurosurgery: Case Lessons.2021;[Epub]     CrossRef
  • Clinicopathologic Features of Thoracolumbar Interdural Disc Herniations: A Retrospective Case Series with a Systematic Literature Review
    Vito Fiorenza, Francesco Ascanio, Ida Di Lorenzo
    World Neurosurgery.2020; 139: e391.     CrossRef
  • Clinical case: conservative treatment of sequestered disc herniation
    Inna Afanasyeva, Iryna Andrushchenko, Taras Bezghodov
    Radiation Diagnostics, Radiation Therapy.2020; (1): 67.     CrossRef
  • Clinical Efficacy of Intra-Operative Cell Salvage System in Major Spinal Deformity Surgery
    Ho Yong Choi, Seung-Jae Hyun, Ki-Jeong Kim, Tae-Ahn Jahng, Hyun-Jib Kim
    Journal of Korean Neurosurgical Society.2019; 62(1): 53.     CrossRef
  • Misdiagnosis of posterior sequestered lumbar disc herniation: report of three cases and review of the literature
    Antonio Montalvo Afonso, Olga Mateo Sierra, Oscar Lucas Gil de Sagredo del Corral, Antonio José Vargas López, Lain Hermes González-Quarante, Emma Sola Vendrell, Julia Romero Martínez
    Spinal Cord Series and Cases.2018;[Epub]     CrossRef
  • Spinal Deformity Surgery : It Becomes an Essential Part of Neurosurgery
    Seung-Jae Hyun, Jong-myung Jung
    Journal of Korean Neurosurgical Society.2018; 61(6): 661.     CrossRef
  • Total Deformity Angular Ratio as a Risk Factor for Complications after Posterior Vertebral Column Resection Surgery
    Byoung Hun Lee, Seung-Jae Hyun, Sanghyun Han, Se-Il Jeon, Ki-Jeong Kim, Tae-Ahn Jahng, Hyun-Jib Kim
    Journal of Korean Neurosurgical Society.2018; 61(6): 723.     CrossRef
  • A Case of Intradural Disc Herniation Mimicking a Schwannoma
    Nobuhiro Sasaki, Hiroaki Manabe, Miyuki Fukuda, Tomoaki Fujita, Minoru Houshimaru, Shigeo Ueda
    Spinal Surgery.2018; 32(3): 316.     CrossRef
  • 10,394 View
  • 96 Download
  • 15 Crossref

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Free Vascularized Fibular Strut Autografts to the Lumbar Spine in Complex Revision Surgery: A Report of Two Cases
Korean J Spine. 2015;12(3):185-189.   Published online September 30, 2015
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Free Vascularized Fibular Strut Autografts to the Lumbar Spine in Complex Revision Surgery: A Report of Two Cases
Korean J Spine. 2015;12(3):185-189.   Published online September 30, 2015
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This case report presents two patients who underwent fibular strut grafting for complex revisions of previous lumbar spine arthrodeses. A case review of the Electronic Medical Record at the index institution was performed to evaluate the timeline of events of the two patients who underwent fibular strut grafting for complex revisions of previous lumbar spine arthrodesis, including imaging studies, progress notes, and laboratory results. One patient had developed chronic L3 vertebral body osteomyelitis from a prior fibular allograft and instrumentation placed for a traumatic burst fracture. The second patient had a severe scoliosis recalcitrant to prior arthrodeses in the context of Marfan syndrome and a persistent L4-5 pseudarthrosis. Both patients underwent free vascularized fibular autograft revision arthrodeses. At most recent long-term follow-up, both patients had improved clinically and neither had required further revision. The use of free vascularized fibular grafting is an excellent option for a variety of spinal indications, and these two reports indicate that the technology may have an indication for use after multiple failed surgeries for osteomyelitis or correction of a multi-level large spinal deformity secondary to Marfan syndrome.

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  • Free Vascularized Osseous Fibula Flap for Vertebral Body Defect in a Patient with Tuberculosis Spondylitis
    Parintosa Atmodiwirjo, Mohamad Rachadian Ramadan, Ruth Lumbuun, Kevin Gunawan, Mohamad Saekhu, Setyo Widi Nugroho, Nadhira Anindita Ralena
    Plastic and Reconstructive Surgery - Global Open.2024; 12(9): e6169.     CrossRef
  • Is it Safe to Use Synthetic Grafts in Pyogenic Vertebral Osteodiskitis When Surgical Debridement is Required?
    Sameer K. Saxena, Patrick D. Grimm, Husain M. Bharmal
    Clinical Spine Surgery: A Spine Publication.2018; 31(7): 269.     CrossRef
  • Outcomes and Complications of Reconstruction with Use of Free Vascularized Fibular Graft for Spinal and Pelvic Defects Following Resection of a Malignant Tumor
    Matthew T. Houdek, Peter S. Rose, Karim Bakri, Eric R. Wagner, Michael J. Yaszemski, Franklin H. Sim, Steven L. Moran
    Journal of Bone and Joint Surgery.2017; 99(13): e69.     CrossRef
  • 9,917 View
  • 72 Download
  • 3 Crossref

Clinical Article

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Influence of Alendronate and Endplate Degeneration to Single Level Posterior Lumbar Spinal Interbody Fusion
Korean J Spine. 2014;11(4):221-226.   Published online December 31, 2014
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Influence of Alendronate and Endplate Degeneration to Single Level Posterior Lumbar Spinal Interbody Fusion
Korean J Spine. 2014;11(4):221-226.   Published online December 31, 2014
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Objective

Using alendronate after spinal fusion is a controversial issue due to the inhibition of osteoclast mediated bone resorption. In addition, there are an increasing number of reports that the endplate degeneration influences the lumbar spinal fusion. The object of this retrospective controlled study was to evaluate how the endplate degeneration and the bisphosphonate medication influence the spinal fusion through radiographic evaluation.

Methods

In this study, 44 patients who underwent single-level posterior lumbar interbody fusion (PLIF) using cage were examined from April 2007 to March 2009. All patients had been diagnosed as osteoporosis and would be recommended for alendronate medication. Endplate degeneration is categorized by the Modic changes. The solid fusion is defined if there was bridging bone between the vertebral bodies, either within or external to the cage on the plain X-ray and if there is less than 5° of angular difference in dynamic X-ray.

Results

In alendronate group, fusion was achieved in 66.7% compared to 73.9% in control group (no medication). Alendronate did not influence the fusion rate of PLIF. However, there was the statistical difference of fusion rate between the endplate degeneration group and the group without endplate degeneration. A total of 52.4% of fusion rate was seen in the endplate degeneration group compared to 91.3% in the group without endplate degeneration. The endplate degeneration suppresses the fusion process of PLIF.

Conclusion

Alendronate does not influence the fusion process in osteoporotic patients. The endplate degeneration decreases the fusion rate.

Citations

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  • Antiosteoporosis medication in patients with posterior spine fusion: a systematic review and meta-analysis
    HyungSub Jin, HyungJu Jin, Kyung-Soo Suk, Byung Ho Lee, Si Young Park, Hak-Sun Kim, Seong-Hwan Moon, Sub-Ri Park, Namhoo Kim, Jae Won Shin, Ji-Won Kwon
    The Spine Journal.2025; 25(9): 1877.     CrossRef
  • Osteoporosis in Adult Patients Undergoing Spinal Reconstructive Surgery: Associated Complications and Management
    Zeeshan Sardar, Josephine Coury, David Polly, Kenneth Cheung, Stephen J. Lewis
    Global Spine Journal.2025;[Epub]     CrossRef
  • A new modic changes classification and its impact on posterior lumbar interbody fusion
    Xiong Zhang, Xiaoxia Qiao, Xiaozhe Zhou, Linfeng Wang
    BMC Musculoskeletal Disorders.2025;[Epub]     CrossRef
  • Evaluating osteoporosis and bone quality in the aging spine: modern considerations for surgical management in the geriatric population
    Miles Hudson, Jenna Meyer, Alexander Evans, Chandan Krishna, Zachary A. Smith, Joshua Bakhsheshian
    GeroScience.2024; 46(5): 5287.     CrossRef
  • Do modic changes affect the fusion rate in spinal interbody fusion surgery? A systematic review and network meta-analysis
    Rigao Chen, Kai Zou, Jianjia Liu, Ke Li, Yi Zhou, Haoyun Huang, Fei Yang
    Journal of Clinical Neuroscience.2024; 125: 110.     CrossRef
  • Effects of anti-osteoporosis treatment in elderly patients with osteoporosis and lumbar discectomy and fusion
    Tao Shi, Fenyong Shou, Qun Xia, Tao Zhang, Donghui Teng, Wanli Jing, Qiang Zhou
    Journal of Back and Musculoskeletal Rehabilitation.2024; 37(5): 1277.     CrossRef
  • Medical optimization of osteoporosis for adult spinal deformity surgery: a state-of-the-art evidence-based review of current pharmacotherapy
    Andrew S. Zhang, Surya Khatri, Mariah Balmaceno-Criss, Daniel Alsoof, Alan H. Daniels
    Spine Deformity.2023; 11(3): 579.     CrossRef
  • Peri-operative optimization in adult spinal deformity surgery
    Bilal B. Butt, Jetan H. Badhiwala, Jason W. Savage
    Seminars in Spine Surgery.2023; 35(2): 101026.     CrossRef
  • Does Preoperative Modic Changes Influence the Short‐term Fusion Rate of Single Level Transforaminal Lumbar Interbody Fusion?—a Matched‐pair Case Control Study
    Yang Xiao, Peng Xiu, Xi Yang, Liang Wang, Tao Li, Quan Gong, Limin Liu, Yueming Song
    Orthopaedic Surgery.2023; 15(9): 2309.     CrossRef
  • Influence of Modic Changes on Cage Subsidence and Intervertebral Fusion after Single-Level Anterior Cervical Corpectomy and Fusion
    Jia Li, Jingtao Zhang, Tong Tong, Yong Shen
    Journal of Investigative Surgery.2022; 35(2): 301.     CrossRef
  • Best Practice Guidelines for Assessment and Management of Osteoporosis in Adult Patients Undergoing Elective Spinal Reconstruction
    Zeeshan M. Sardar, Josephine R. Coury, Meghan Cerpa, Christopher J. DeWald, Christopher P. Ames, Christopher Shuhart, Colleen Watkins, David W. Polly, Douglas R. Dirschl, Eric O. Klineberg, John R. Dimar, Kelly D. Krohn, Khaled M. Kebaish, Laura L. Tosi,
    Spine.2022; 47(2): 128.     CrossRef
  • Timing of osteoporosis therapies following fracture: the current status
    Rajan Palui, Harsh Durgia, Jayaprakash Sahoo, Dukhabandhu Naik, Sadishkumar Kamalanathan
    Therapeutic Advances in Endocrinology and Metabolism.2022;[Epub]     CrossRef
  • Postoperative bisphosphonate do not significantly alter the fusion rate after lumbar spinal fusion: a meta-analysis
    Jun Mei, Xiaoxu Song, Xiaoming Guan, Dou Wu, Junjie Wang, Qiang Liu
    Journal of Orthopaedic Surgery and Research.2021;[Epub]     CrossRef
  • Clinical and radiographic outcomes of hybrid graft in patients with Modic changes undergoing transforaminal lumbar interbody fusion
    Jiaxun Jiao, Jiaqi Li, Yun Luo, Wei Zhang
    Journal of Orthopaedic Surgery and Research.2021;[Epub]     CrossRef
  • Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for Perioperative Spine: Preoperative Osteoporosis Assessment
    John Dimar, Erica F Bisson, Sanjay Dhall, James S Harrop, Daniel J Hoh, Basma Mohamed, Marjorie C Wang, Praveen V Mummaneni
    Neurosurgery.2021; 89(Supplement): S19.     CrossRef
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    Hong Yoon, Jung-Ho Kim, Dal-Sung Ryu, Seung-Hwan Yoon
    The Nerve.2021; 7(2): 64.     CrossRef
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    Vaidya Govindarajan, Anthony Diaz, Roberto J. Perez-Roman, S. Shelby Burks, Michael Y. Wang, Allan D. Levi
    Neurosurgical Focus.2021; 50(6): E9.     CrossRef
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    Dallas L. Sheinberg, Roberto J. Perez-Roman, Julian G. Lugo-Pico, Iahn Cajigas, Karthik H. Madhavan, Barth A. Green, Joseph P. Gjolaj
    Journal of Clinical Neuroscience.2020; 77: 157.     CrossRef
  • Pharmacologic considerations in patients with osteoporosis undergoing lumbar interbody fusion: A systematic review
    Sauson Soldozy, Danyas Sarathy, Anthony Skaff, Samuel R. Montgomery, Steven Young, Bhargav Desai, Jennifer D. Sokolowski, Avery L. Buchholz, Mark E. Shaffrey, Hasan R. Syed
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    Sung Huang Laurent Tsai, Ruei-Shyuan Chien, Katie Lichter, Raghad Alharthy, Mohammed Ali Alvi, Anshit Goyal, Mohamad Bydon, Tsai-Sheng Fu, Tung-Yi Lin
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    Neurosurgical Focus.2020; 49(2): E12.     CrossRef
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    S. McCoy, F. Tundo, S. Chidambaram, A.A. Baaj
    Clinical Neurology and Neurosurgery.2019; 180: 40.     CrossRef
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    Matthew T. Morris, Sandip P. Tarpada, Vafa Tabatabaie, Woojin Cho
    Archives of Osteoporosis.2018;[Epub]     CrossRef
  • Bisphosphonate's and Intermittent Parathyroid Hormone's Effect on Human Spinal Fusion: A Systematic Review of the Literature
    Michael A. Stone, Andre M. Jakoi, Justin A. Iorio, Martin H. Pham, Neil N. Patel, Patrick C. Hsieh, John C. Liu, Frank L. Acosta, Raymond Hah, Jeffrey C. Wang
    Asian Spine Journal.2017; 11(3): 484.     CrossRef
  • Atypical Complete Femoral Fractures Associated with Bisphosphonate Use or Not Associated with Bisphosphonate Use: Is There a Difference?
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    Charla R. Fischer, Gregory Hanson, Melinda Eller, Ronald A. Lehman
    Geriatric Orthopaedic Surgery & Rehabilitation.2016; 7(4): 188.     CrossRef
  • 10,578 View
  • 91 Download
  • 26 Crossref