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Functional Resilience in Chronic Low Back Pain: Dissociating Magnetic Resonance Imaging Abnormalities From Real-World Disability in the Wakayama Spine Study
Neurospine. 2026;23(2):276-289.   Published online April 30, 2026
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Functional Resilience in Chronic Low Back Pain: Dissociating Magnetic Resonance Imaging Abnormalities From Real-World Disability in the Wakayama Spine Study
Neurospine. 2026;23(2):276-289.   Published online April 30, 2026
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Objective
Low back pain (LBP) is common, yet many individuals maintain normal activities of daily living despite chronic symptoms and structural changes evident on imaging. We hypothesized that functional resilience, defined as preserved functional capacity despite pain and age‑typical degenerative changes, represents a meaningful clinical phenotype, and that function‑centered outcome measures would better discriminate disability status than structural imaging features.
Methods
This study analyzed 347 participants reporting LBP from the Wakayama Spine Study (N=866). Maintained function was defined a priori as Oswestry Disability Index (ODI) ≤20%. We compared those with maintained function (n=220, 63.4%) to those with impairment (n=127) across demographics, lifestyle, metabolic components, physical performance (grip strength, gait speed), and lumbar magnetic resonance imaging (MRI) findings. Multivariable logistic regression among participants with LBP, including age, sex, obesity, metabolic factors, pain intensity, physical performance, and MRI phenotypes, was used to identify independent predictors of functional resilience.
Results
Functional resilience was common: 63.0% of LBP participants had ODI ≤20%. Resilient individuals were younger (65.0±11.9 years vs. 74.6±10.9 years, p<0.001) with superior physical performance. In multivariable models, male sex predicted maintained function (odds ratio [OR], 1.76; 95% confidence interval [CI], 1.03–3.00; p<0.05), while obesity (body mass index ≥25 kg/m2) was associated with reduced odds of resilience (OR, 0.50; 95% CI, 0.30–0.84; p<0.01). Standard MRI features, including disc degeneration, Modic changes, and Schmorl nodes, were not independently associated with functional status after adjustment, despite disc degeneration being highly prevalent even among resilient participants (95.4%).
Conclusion
These data confirm that functional resilience is common in LBP and is not negated by the presence of structural MRI abnormalities. Among LBP patients, male sex and absence of obesity are independent predictors of maintained function, whereas standard MRI features do not independently predict functional status after age adjustment. Function-centered metrics (ODI, gait speed, grip strength) better discriminate functional status than structural imaging findings.

Citations

Citations to this article as recorded by  Crossref logo
  • From the Editor-in-Chief: Featured Articles in the April 2026 Issue
    Inbo Han
    Neurospine.2026; 23(2): 227.     CrossRef
  • A Commentary on “Functional Resilience in Chronic Low Back Pain: Dissociating Magnetic Resonance Imaging Abnormalities From Real-World Disability in the Wakayama Spine Study”
    Shigeo Ueda
    Neurospine.2026; 23(2): 290.     CrossRef
  • 593 View
  • 24 Download
  • 2 Crossref

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Effects of Obesity on Cervical Disc Arthroplasty Complications
Neurospine. 2023;20(4):1399-1406.   Published online December 31, 2023
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Effects of Obesity on Cervical Disc Arthroplasty Complications
Neurospine. 2023;20(4):1399-1406.   Published online December 31, 2023
Close
Objective
High body mass index is a well-established modifiable comorbidity that is known to increase postoperative complications in all types of surgery, including spine surgery. Obesity is increasing in prevalence amongst the general population. As this growing population of obese patients ages, understanding how they faire undergoing cervical disc arthroplasty (CDA) is important for providing safe and effective evidence-based care for cervical degenerative pathology.
Methods
Our study used the Healthcare Cost and Utilization Project’s National Inpatient Sample to assess patients undergoing CDA comparing patient characteristics and outcomes in nonobese patients to obese patients from 2004 to 2014.
Results
Our study found a significant increase in the overall utilization of CDA as a treatment modality (p = 0.012) and a statistically significant increase in obese patients undergoing CDA (p < 0.0001) from 2004 to 2014. Obesity was identified as an independent risk factor associated with increased rates of inpatient neurologic complications (odds ratio [OR], 6.99; p = 0.03), pulmonary embolus (OR, 5.41; p = 0.05), and wound infection (OR, 6.97; p < 0.001) in patients undergoing CDA from 2004 to 2014.
Conclusion
In patients undergoing CDA, from 2004 to 2014, obesity was identified as an independent risk factor with significantly increased rates of inpatient neurologic complications, pulmonary embolus and wound infection. Large prospective trials are needed to validate these findings.

Citations

Citations to this article as recorded by  Crossref logo
  • Inpatient National Trends and Aggregate Costs of Primary and Revision Lumbar Fusion in the United States from 2016 to 2022
    Mitchell K. Ng, Leonidas E. Mastrokostas, Paul G. Mastrokostas, Yulia Lee, Sean Inzerillo, Jonathan Dalton, Arya Varthi, Jad Bou Monsef, Afshin E. Razi, Jose A. Canseco, Thomas D. Cha, Alan S. Hilibrand, Alexander R. Vaccaro, Gregory D. Schroeder, Christo
    The Spine Journal.2026;[Epub]     CrossRef
  • Cervical disc arthroplasty is safe across various obesity levels
    Manjot Singh, Benjamin Chanes, Mariah Balmaceno-Criss, Alan H. Daniels, Andrew S Zhang
    The Spine Journal.2025; 25(4): 756.     CrossRef
  • Single-level anterior cervical discectomy and fusion is associated with higher nonroutine discharge rates compared to cervical disc arthroplasty in obese patients
    Paul G. Mastrokostas, Luke B. Schwartz, Eli Berglas, Aaron B. Lavi, Leonidas E. Mastrokostas, Jonathan Dalton, Christopher K. Kepler, Arya Varthi, Jad Bou Monsef, Afshin E. Razi, Mitchell K. Ng
    Journal of Craniovertebral Junction and Spine.2025; 16(2): 205.     CrossRef
  • A systematic review of intervertebral disc degeneration clinical trial protocols
    Francis Chemorion, Jerome Noailly, Marc-Antonio Bisotti
    Open Research Europe.2025; 5: 284.     CrossRef
  • Sexual Dimorphism in the Atlas Vertebra of Normal and Overweight Patients with its Possible Surgical Implications
    Nilgün Tuncel Çini, Mathias Orellana-Donoso, Guinevere Granite, Pablo Nova-Baeza, Federico Mata-Escolano, Esther Blanco-Perez, Juan José Valenzuela-Fuenzalida, Maria Piagkou, George Triantafyllou, Marko Konschake, Juan A. Sanchis-Gimeno
    World Neurosurgery.2025; 204: 124531.     CrossRef
  • Biomechanical Analysis of Hybrid Artificial Discs or Zero-Profile Devices for Treating 1-Level Adjacent Segment Degeneration in ACDF Revision Surgery
    Weishi Liang, Yihan Yang, Bo Han, Duan Sun, Peng Yin, Yong Hai
    Neurospine.2024; 21(2): 606.     CrossRef
  • Beyond the Label: Extended Indications for Cervical Disc Arthroplasty
    Annika Bay, Eric R. Zhao, Cole T. Kwas, Chad Z. Simon, Tomoyuki Asada, Sheeraz A. Qureshi
    Contemporary Spine Surgery.2024; 25(12): 1.     CrossRef
  • 5,006 View
  • 197 Download
  • 5 Web of Science
  • 7 Crossref

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Severe Obesity Is an Independent Risk Factor of Early Readmission and Nonhome Discharge After Cervical Disc Replacement
Neurospine. 2023;20(3):890-898.   Published online September 30, 2023
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Severe Obesity Is an Independent Risk Factor of Early Readmission and Nonhome Discharge After Cervical Disc Replacement
Neurospine. 2023;20(3):890-898.   Published online September 30, 2023
Close
Objective
Despite growing interest in cervical disc replacement (CDR) for conditions such as cervical radiculopathy, limited data exists describing the impact of obesity on early postoperative outcomes and complications. These data are especially important as nearly half of the adult population in the United States is expected to become obese (body mass index [BMI] ≥ 30 kg/m2) by 2030. The goal of this study was to compare the demographics, perioperative variables, and complication rates following CDR.
Methods
The 2005–2020 American College of Surgeons National Surgical Quality Improvement Program datasets were queried for patients who underwent primary 1- or 2-level CDR. Patients were divided into 3 cohorts: Nonobese (BMI: 18.5–29.9 kg/m2), Obese class-I (BMI: 30–34.9 kg/m2), Obese class-II/III (BMI ≥ 35 kg/m2). Morbidity was defined as the presence of any complication within 30 days postoperatively. Rates of 30-day readmission, reoperation, morbidity, individual complications, length of stay, frequency of nonhome discharge disposition were collected.
Results
A total of 5,397 patients were included for analysis: 3,130 were nonobese, 1,348 were obese class I, and 919 were obese class II/III. There were more 2-level CDRs performed in the class II/III cohort compared to the nonobese group (25.7% vs. 21.5%, respectively; p < 0.05). Class-II/III had more nonhome discharges than class I and nonobese (2.1% vs. 0.5% vs. 0.7%, respectively; p < 0.001). Readmission rates differed as well (nonobese: 0.5%, class I: 1.1%, class II/III: 2.1%; p < 0.001) with pairwise significance between class II/II and nonobese. Class II/III obesity was an independent risk factor for both readmission (odds ratio [OR], 3.32; p = 0.002) and nonhome discharge (OR, 2.51; p = 0.02). Neither 30-day reoperation nor morbidity rates demonstrated significance. No mortalities were reported.
Conclusion
Although obese class-II/III were risk factors for 30-day readmission and nonhome discharge, there was no significant difference in reoperation rates or morbidity. CDR procedures can continue to be safely preformed independent of obesity status.

Citations

Citations to this article as recorded by  Crossref logo
  • The Impact of Obesity on Spine Surgery Operative Time: A Quantitative Analysis
    Haseeb E. Goheer, Mina Botros, Andrew R. Leggett, Gabriel Ramirez, Ram Haddas, Robert W. Molinari, Varun Puvanesarajah
    Global Spine Journal.2026; 16(2): 975.     CrossRef
  • Preoperative Disability Influences Effectiveness of Minimal Clinically Important Difference and Patient Acceptable Symptom State in Predicting Patient Improvement Following Cervical Spine Surgery
    Pratyush Shahi, Omri Maayan, Tejas Subramanian, Nishtha Singh, Sumedha Singh, Kasra Araghi, Olivia Tuma, Tomoyuki Asada, Maximilian Korsun, Evan Sheha, James Dowdell, Sheeraz A. Qureshi, Sravisht Iyer
    Global Spine Journal.2025; 15(2): 884.     CrossRef
  • Obesity is an independent risk factor for postoperative pulmonary embolism after anterior cervical discectomy and fusion
    Haseeb E. Goheer, Christopher G. Hendrix, Linsen T. Samuel, Alden H. Newcomb, Jonathan J. Carmouche
    The Spine Journal.2025; 25(2): 299.     CrossRef
  • Cervical disc arthroplasty is safe across various obesity levels
    Manjot Singh, Benjamin Chanes, Mariah Balmaceno-Criss, Alan H. Daniels, Andrew S Zhang
    The Spine Journal.2025; 25(4): 756.     CrossRef
  • Class 2/3 obesity leads to worse outcomes following minimally invasive transforaminal lumbar interbody fusion
    Pratyush Shahi, Tejas Subramanian, Kasra Araghi, Maximilian K. Korsun, Sumedha Singh, Nishtha Singh, Olivia C. Tuma, Tomoyuki Asada, Annika Bay, Eric R. Zhao, Adin M. Ehrlich, Sereen Halayqeh, Tarek Harhash, Andrea Pezzi, Adrian Lui, Evan D. Sheha, James
    The Spine Journal.2025; 25(9): 1985.     CrossRef
  • Morbidly Obese Patients Have Similar Clinical Outcomes and Recovery Kinetics After Minimally Invasive Decompression
    Pratyush Shahi, Tejas Subramanian, Sumedha Singh, Kasra Araghi, Tomoyuki Asada, Maximilian Korsun, Nishtha Singh, Olivia Tuma, Chad Simon, Avani Vaishnav, Eric Mai, Joshua Zhang, Cole Kwas, Myles Allen, Eric Kim, Annika Heuer, Evan Sheha, James Dowdell, S
    Spine.2025; 50(5): 318.     CrossRef
  • Risk Factors of 90-Day Unplanned Readmission After Lumbar Spine Surgery for Degenerative Lumbar Disk Disease: A Systematic Review and Meta-Analysis
    Jeong In Seol, Jeong Hoon Yoo, Hyeon Gyu Sung, Hyun Ho Park, Sung Hyeon Noh
    Neurosurgery.2025; 97(4): 908.     CrossRef
  • Single-level anterior cervical discectomy and fusion is associated with higher nonroutine discharge rates compared to cervical disc arthroplasty in obese patients
    Paul G. Mastrokostas, Luke B. Schwartz, Eli Berglas, Aaron B. Lavi, Leonidas E. Mastrokostas, Jonathan Dalton, Christopher K. Kepler, Arya Varthi, Jad Bou Monsef, Afshin E. Razi, Mitchell K. Ng
    Journal of Craniovertebral Junction and Spine.2025; 16(2): 205.     CrossRef
  • Thirty-day unplanned readmission rates and risk factors in spine surgery: a systematic review and meta-analysis
    Ya-Nan Gong, Mei-Qing Lin, Bi-Zhen Chen, Chen Wu, Qiu-Ling Zheng
    Journal of Orthopaedic Surgery and Research.2025;[Epub]     CrossRef
  • Anterior cervical surgery for morbidly obese patients should be performed in-hospitals
    Nancy E. Epstein, Marc A. Agulnick
    Surgical Neurology International.2024; 15: 2.     CrossRef
  • Practical Answers to Frequently Asked Questions in Anterior Cervical Spine Surgery for Degenerative Conditions
    Tejas Subramanian, Austin Kaidi, Pratyush Shahi, Tomoyuki Asada, Takashi Hirase, Avani Vaishnav, Omri Maayan, Troy B. Amen, Kasra Araghi, Chad Z. Simon, Eric Mai, Olivia C. Tuma, Ashley Yeo Eun Kim, Nishtha Singh, Maximillian K. Korsun, Joshua Zhang, Myle
    Journal of the American Academy of Orthopaedic Surgeons.2024; 32(18): e919.     CrossRef
  • Predictors of Nonhome Discharge After Cervical Disc Replacement
    Tejas Subramanian, Junho Song, Yeo Eun Kim, Omri Maayan, Robert Kamil, Pratyush Shahi, Daniel Shinn, Sidhant Dalal, Kasra Araghi, Tomoyuki Asada, Troy B. Amen, Evan Sheha, James Dowdell, Sheeraz Qureshi, Sravisht Iyer
    Clinical Spine Surgery.2024; 37(7): E324.     CrossRef
  • Beyond the Label: Extended Indications for Cervical Disc Arthroplasty
    Annika Bay, Eric R. Zhao, Cole T. Kwas, Chad Z. Simon, Tomoyuki Asada, Sheeraz A. Qureshi
    Contemporary Spine Surgery.2024; 25(12): 1.     CrossRef
  • 4,643 View
  • 130 Download
  • 12 Web of Science
  • 13 Crossref

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Effects of Body Mass Index on Perioperative Outcomes in Patients Undergoing Anterior Cervical Discectomy and Fusion Surgery
Neurospine. 2021;18(1):79-86.   Published online November 17, 2020
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Effects of Body Mass Index on Perioperative Outcomes in Patients Undergoing Anterior Cervical Discectomy and Fusion Surgery
Neurospine. 2021;18(1):79-86.   Published online November 17, 2020
Close
Objective
Obesity has become a public health crisis and continues to be on the rise. An elevated body mass index has been linked to higher rates of spinal degenerative disease requiring surgical intervention. Limited studies exist that evaluate the effects of obesity on perioperative complications in patients undergoing anterior cervical discectomy and fusion (ACDF). Our study aims to determine the incidence of obesity in the ACDF population and the effects it may have on postoperative inpatient complications.
Methods
The National Inpatient Sample was evaluated from 2004 to 2014 and discharges with International Classification of Diseases procedure codes indicating ACDF were identified. This cohort was stratified into patients with diagnosis codes indicating obesity. Separate univariable followed by multivariable logistic regression analysis were performed for the likelihood of perioperative inpatient outcomes among the patients with obesity.
Results
From 2004 to 2014, estimated 1,212,475 ACDFs were identified in which 9.2% of the patients were obese. The incidence of obesity amongst ACDF patients has risen dramatically during those years from 5.8% to 13.4%. Obese ACDF patients had higher inpatient likelihood of dysphagia, neurological, respiratory, and hematologic complications as well as pulmonary emboli, and intraoperative durotomy.
Conclusion
Obesity is a well-established modifiable comorbidity that leads to increased perioperative complications in various surgical specialties. We present one of the largest retrospective analyses evaluating the effects of obesity on inpatient complications following ACDF. Our data suggest that the number of obese patients undergoing ACDF is steadily increasing and had a higher inpatient likelihood of developing perioperative complications.

Citations

Citations to this article as recorded by  Crossref logo
  • Glucagon-like peptide-1 receptor agonist use and perioperative outcomes after anterior cervical discectomy and fusion: a propensity-matched cohort study
    Kevin Y. Heo, Stephen R. Barchick, Aubrie M. Sowa, Myra Chao, Prashant V. Rajan, Brian C. Goh, Sangwook T. Yoon
    The Spine Journal.2026; 26(5): 882.     CrossRef
  • Obesity does not significantly impact clinical outcomes following anterior cervical discectomy and fusion
    Ishan Shah, Alejandro Perez-Albela, Riya Shah, Charles Furlong, Puru Sadh, John Czerwein, Alan Daniels, Bryce A. Basques
    Journal of Clinical Neuroscience.2026; 144: 111807.     CrossRef
  • The Effect of GLP-1 Receptor Agonists on Reoperation Following Anterior Cervical Discectomy and Fusion
    Nicholas C. Bank, Daniel Whittingslow, Sam Duggan, Joshua L. Morningstar, Douglas S. Weinberg
    World Neurosurgery.2026; 206: 124751.     CrossRef
  • Impact of obesity on patient-reported outcome measures and complications following anterior cervical surgery for cervical spondylosis: A cohort study Of 7,993 patients
    Edisson Nemer, Victor Gabriel El-Hajj, Marcus Roland Victor Gustafsson, Victor E. Staartjes, Erik Edström, Adrian Elmi-Terander
    European Spine Journal.2026;[Epub]     CrossRef
  • Surgical outcomes following multi-level sub-axial anterior cervical discectomy and fusion versus posterior cervical decompression and fusion in an obese cohort
    Taylor Furst, Aman Singh, Prasanth Romiyo, Jonathan Stone, Tyler Schmidt
    British Journal of Neurosurgery.2026; : 1.     CrossRef
  • Cervical disc arthroplasty is safe across various obesity levels
    Manjot Singh, Benjamin Chanes, Mariah Balmaceno-Criss, Alan H. Daniels, Andrew S Zhang
    The Spine Journal.2025; 25(4): 756.     CrossRef
  • Impact of Severe Obesity on Outcomes in Single-Level Anterior Cervical Discectomy and Fusion (ACDF): A Large-Scale Comparative Study
    David Maman, Ofek Bar, Yaniv Steinfeld, Ali Sleiman, Arsen Shpigelman, Lior Ben Zvi, Yaron Berkovich
    Surgical Techniques Development.2025; 14(1): 1.     CrossRef
  • Factors predicting outcomes from chronic pain management interventions
    Steven P Cohen, Eric J Wang, Alexandra Roybal, Yian Chen
    BMJ Medicine.2025; 4(1): e001143.     CrossRef
  • Single-level anterior cervical discectomy and fusion is associated with higher nonroutine discharge rates compared to cervical disc arthroplasty in obese patients
    Paul G. Mastrokostas, Luke B. Schwartz, Eli Berglas, Aaron B. Lavi, Leonidas E. Mastrokostas, Jonathan Dalton, Christopher K. Kepler, Arya Varthi, Jad Bou Monsef, Afshin E. Razi, Mitchell K. Ng
    Journal of Craniovertebral Junction and Spine.2025; 16(2): 205.     CrossRef
  • Standardizing Preoperative Care for Elective Spine Surgery: The University of Oklahoma Elective Spine Surgery Protocol
    Lonnie Smith, David Barkyoumb, William C. Kaiser, Fauziyya Muhammad, Tara Sukut, Ishan Purani, Chao Li, DO, Karl Balsara, Hakeem J. Shakir, M. Burhan Janjua, John F. Burke, Andrew Jea, Zachary A. Smith
    GeroScience.2025;[Epub]     CrossRef
  • Postoperative Physical Therapy Utilization for Anterior Cervical Discectomy and Fusion
    Justin M. Lantz, William J. Karakash, Andy T. Ton, Andreas Remis, Henry Avetisian, David B. Anderson, Yogi Matharu, Ram K. Alluri, Zorica Buser
    Spine.2025; 50(22): 1547.     CrossRef
  • Complication Rates, Operative Times, and Hospital Costs Following Anterior Cervical Discectomy and Fusion in Obese Versus Nonobese Patients
    Stavros Matsoukas, Teleale Gebeyehu, Joshua E. Heller, Jack Jallo, James S. Harrop, Srinivas K. Prasad
    Clinical Spine Surgery.2025;[Epub]     CrossRef
  • The Impact of Obesity on Fusion Rate Following Anterior Cervical Discectomy and Fusion: A Population-Based Study
    Wei-Thing Khor, Yu Chang, Hong-Min Lin, Kuan-Yu Chi, Junmin Song, Chien-Min Chen, Chi-Chen Huang
    World Neurosurgery.2025; 204: 124595.     CrossRef
  • Anterior cervical surgery for morbidly obese patients should be performed in-hospitals
    Nancy E. Epstein, Marc A. Agulnick
    Surgical Neurology International.2024; 15: 2.     CrossRef
  • Trends in Indications and Contraindications for Cervical Disk Arthroplasty from 2009 to 2019
    Karim Shafi, Jerry Y. Du, Collin W. Blackburn, Han Jo Kim, Sravisht Iyer, Sheeraz Qureshi, Randall E. Marcus, Todd J. Albert
    Clinical Spine Surgery.2024; 37(7): E283.     CrossRef
  • Disability and pain after anterior cervical decompression and fusion: A group-based trajectory analysis
    Sara S. Widbom-Kolhanen, Katri I. Pernaa, Roosa E. Lintuaho, Anna Kotkansalo, Mikhail Saltychev
    Scandinavian Journal of Surgery.2024; 113(2): 166.     CrossRef
  • The Effect of the Coronavirus Disease 2019 Pandemic on Pituitary Surgery
    Evan Luther, Ian Ramsay, Vaidya Govindarajan, Chandler N. Berke, Vivien Makhoul, Martin Merenzon, Katherine Berry, Alexis Morell, Daniel Eichberg, Victor M. Lu, Ashish Shah, Ricardo J. Komotar, Michael E. Ivan
    World Neurosurgery.2024; 186: e440.     CrossRef
  • The Effect of Patient Resilience on Postoperative Scores After One- and Two-Level Anterior Cervical Discectomy and Fusion
    Matthew H. Meade, Tyler Radack, Samantha Riebesell, Matthew J. Schultz, Levi Buchan, Alan S. Hilibrand, Mark F. Kurd, Victor Hsu, Ian David Kaye, Gregory D. Schroeder, Christopher Kepler, Alexander R. Vaccaro, Barrett I. Woods
    World Neurosurgery.2024; 189: e953.     CrossRef
  • Leveraging HFRS to assess how frailty affects healthcare resource utilization after elective ACDF for CSM
    Aladine A. Elsamadicy, Andrew B. Koo, Margot Sarkozy, Wyatt B. David, Benjamin C. Reeves, Saarang Patel, Justice Hansen, Mani Ratnesh S. Sandhu, Astrid C. Hengartner, Andrew Hersh, Luis Kolb, Sheng-Fu Larry Lo, John H. Shin, Ehud Mendel, Daniel M. Sciubba
    The Spine Journal.2023; 23(1): 124.     CrossRef
  • Intraoperative Monitoring of the Recurrent Laryngeal Nerve with Electromyography Endotracheal Tube in Anterior Cervical Discectomy and Fusion
    Nattawut Niljianskul, I-Sorn Phoominaonin, Alongkorn Jaiimsin
    World Neurosurgery: X.2023; 17: 100141.     CrossRef
  • Anterior Cervical Discectomy and Fusion Outcomes in Patients With and Without Bariatric Surgery—Weight Loss Does Make a Difference
    Peter Y. Joo, Justin R. Zhu, Christopher Wilhelm, Kevin Tang, Wesley Day, Jay Moran, Jonathan N. Grauer
    Spine.2023; 48(6): 400.     CrossRef
  • Morbid Obesity Increases Length of Surgery in Elective Anterior Cervical Discectomy and Fusion Procedures but Not Readmission or Reoperation Rates: A Cohort Study
    Evan G. Gross, Nicholas M.B. Laskay, James Mooney, M. Chandler McLeod, Travis J. Atchley, Dagoberto Estevez-Ordonez, Jakub Godzik
    World Neurosurgery.2023; 173: e830.     CrossRef
  • The Optimal Time between Embolization and Surgery for Hypervascular Spinal Metastatic Tumors : A Systematic Review and Meta-Analysis
    Woon Tak Yuh, Junghoon Han, Chang-Hyun Lee, Chi Heon Kim, Hyun-Seung Kang, Chun Kee Chung
    Journal of Korean Neurosurgical Society.2023; 66(4): 438.     CrossRef
  • Severe Obesity Is an Independent Risk Factor of Early Readmission and Nonhome Discharge After Cervical Disc Replacement
    Tejas Subramanian, Daniel Shinn, Pratyush Shahi, Izzet Akosman, Troy Amen, Omri Maayan, Eric Zhao, Kasra Araghi, Junho Song, Sidhant Dalal, James Dowdell, Sravisht Iyer, Sheeraz Qureshi
    Neurospine.2023; 20(3): 890.     CrossRef
  • Enhanced Intervertebral Disc Repair via Genetically Engineered Mesenchymal Stem Cells with Tetracycline Regulatory System
    Yeji Kim, Seong Bae An, Sang-Hyuk Lee, Jong Joo Lee, Sung Bum Kim, Jae-Cheul Ahn, Dong-Youn Hwang, Inbo Han
    International Journal of Molecular Sciences.2023; 24(22): 16024.     CrossRef
  • Effects of Obesity on Cervical Disc Arthroplasty Complications
    Katherine M. Berry, Vaidya Govindarajan, Connor Berger, Krisna Maddy, Roberto J. Perez Roman, Evan M. Luther, Allan D. Levi
    Neurospine.2023; 20(4): 1399.     CrossRef
  • Increased risk of postoperative wound complications among obesity classes II & III after ALIF in 10-year ACS-NSQIP analysis of 10,934 cases
    Evan M. Miller, Beck D. McAllister
    The Spine Journal.2022; 22(4): 587.     CrossRef
  • ZERO-PROFILE DEVICE IMPLANTATION IN ANTERIOR CERVICAL DISCECTOMY AND FUSION: A SINGLE INSTITUTE EXPERIENCE
    Nattawut Niljianskul
    Journal of Southeast Asian Medical Research.2022; 6: e0104.     CrossRef
  • Commentary on “Frailty Status Is a More Robust Predictor Than Age of Spinal Tumor Surgery Outcomes: A NSQIP Analysis of 4,662 Patients”
    Moon-Jun Sohn
    Neurospine.2022; 19(1): 63.     CrossRef
  • Cervical Radiculopathy: Focus on Factors for Better Surgical Outcomes and Operative Techniques
    Kyung-Chung Kang, Tae Su Jang, Cheol Hyun Jung
    Asian Spine Journal.2022; 16(6): 995.     CrossRef
  • The Effect of Diabetes and Metabolic Syndrome on Spine Surgery Outcomes
    Anitesh Bajaj, Rohan M. Shah, Hogan Brecount, Steven Kurapaty, Alpesh A. Patel, Srikanth N. Divi
    Current Reviews in Musculoskeletal Medicine.2022; 16(2): 39.     CrossRef
  • National Trends and Correlates of Dysphagia After Anterior Cervical Discectomy and Fusion Surgery
    Roberto J. Perez-Roman, Evan M. Luther, David McCarthy, Julian G. Lugo-Pico, Roberto Leon-Correa, Steven Vanni, Michael Y. Wang
    Neurospine.2021; 18(1): 147.     CrossRef
  • Independent Association of Obesity and Nonroutine Discharge Disposition After Elective Anterior Cervical Discectomy and Fusion for Cervical Spondylotic Myelopathy
    Andrew B. Koo, Aladine A. Elsamadicy, Margot Sarkozy, Wyatt B. David, Benjamin C. Reeves, Christopher S. Hong, Arianne Boylan, Maxwell Laurans, Luis Kolb
    World Neurosurgery.2021; 151: e950.     CrossRef
  • Commentary: Transcondylar Odontoid Resection and Stabilization for Craniovertebral Degenerative Compression: 2-Dimensional Operative Video
    Evan Luther, Gurvinder Kaur, Ricardo Komotar, Michael Ivan
    Operative Neurosurgery.2021; 21(5): E431.     CrossRef
  • 8,860 View
  • 175 Download
  • 35 Web of Science
  • 34 Crossref

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Fatal Rhabdomyolysis following Spine Surgery in a Morbidly Obese Patient: A Case Report
Korean J Spine. 2014;11(4):238-240.   Published online December 31, 2014
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Fatal Rhabdomyolysis following Spine Surgery in a Morbidly Obese Patient: A Case Report
Korean J Spine. 2014;11(4):238-240.   Published online December 31, 2014
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We generally believe that obese patients are faced on higher risk of developing perioperative complications. Rhabdomyolysis is a rare but potentially life-threatening condition caused by the release of injured skeletal muscle components into the circulation. It usually results from mechanical damage to the muscle, intoxication, or a postictal state after a seizure. In the present study, we have reported a rare case of rhabdomyolysis developing in a morbidly obese patient after upper thoracic spinal fusion surgery. We have found acute renal failure that evolved during the course of treatment resulted in a fatal outcome even though the patient received intensive supportive care. Our experience suggests that this rare complication should be considered in morbidly obese patients and those efforts should be made to avoid rhabdomyolysis.

Citations

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    Elliot Pressman, Brooks Osburn, Andrew Vivas, Paul Krafft, Vladimir Ljubimov, Liwei Chen, Rahul Mhaskar, Puya Alikhani
    British Journal of Neurosurgery.2024; 38(1): 29.     CrossRef
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  • Predictive Factors for Muscle Injury After Posterior Lumbar Spinal Surgery
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    World Neurosurgery.2019; 129: e514.     CrossRef
  • Rhabdomyolysis and spine surgery: A systematic review of the literature
    Stella Taylor Portella, Marcus André Acioly
    Journal of Clinical Neuroscience.2019; 70: 178.     CrossRef
  • The Impact of Kidney Disease on Acute Tubular Necrosis and Surgical Site Infection After Lumbar Fusion
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    World Neurosurgery.2017; 105: 498.     CrossRef
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Clinical Article

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Does Obesity Make an Influence on Surgical Outcomes Following Lumbar Microdiscectomy?
Korean J Spine. 2014;11(2):68-73.   Published online June 30, 2014
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Does Obesity Make an Influence on Surgical Outcomes Following Lumbar Microdiscectomy?
Korean J Spine. 2014;11(2):68-73.   Published online June 30, 2014
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Objective

The purpose of this study was to evaluate the effect of patients' bod mass index (BMI) on surgical outcomes following one-level lumbar microdiscectomy.

Methods

From June 2003 to March 2007, 129 patients underwent one-level lumbar microdiscectomy performed at a single institution. We divided the patients into 3 groups, depending on BMI. A retrospective study was conducted among the 3 groups. The operation time, estimated blood loss (EBL), postoperative hospital day, recurrent disc herniation, intraoperative durotomy, and postoperative epidural steroid injection were analyzed. Regression models were used to predict the relationship between BMI and surgical outcomes including operation time and EBL.

Results

As BMI is greater, as the operation time is longer and the EBL is more. In particular, linear regression model analysis implied that 2.35 minute in the operation time is longer and 8.89cc in EBL is more, as BMI of 1 kg/m2 is increased. No statistically relevant differences were observed for postoperative hospital day, recurrent disc herniation, intraoperative durotomy, and postoperative epidural steroid injection.

Conclusion

The operation time and EBL was significantly increased in obesity, but there were no differences in surgical outcomes. Our results demonstrated that higher BMI are not likely to encounter heightened morbidity in lumbar microdiscectomy.

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    Brain and Spine.2026; 6: 105948.     CrossRef
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    Archives of Orthopaedic and Trauma Surgery.2023; 143(9): 5589.     CrossRef
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    Acta Neurochirurgica.2023; 165(9): 2641.     CrossRef
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    Neurological Research.2022; 44(9): 830.     CrossRef
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    Niyaz Hareni, Fredrik Strömqvist, Björn E. Rosengren, Magnus K. Karlsson
    BMC Musculoskeletal Disorders.2022;[Epub]     CrossRef
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    Global Spine Journal.2018; 8(1): 11.     CrossRef
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  • A Prospective Detailed Time Analysis Study of 18 Patients Undergoing Elective Single-Level Open Lumbar Microdiscectomy Spinal Surgery Compared with Centers for Medicare and Medicaid Services Reimbursement Guidelines
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  • 89 Download
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