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Magnetic Resonance Imaging-Based Vertebral Bone Quality Score for Prediction of Cage Subsidence and Screw Loosening in Patients Undergoing Degenerative Lumbar Surgery: A Meta-analysis
Neurospine. 2024;21(3):913-924.   Published online September 30, 2024
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Magnetic Resonance Imaging-Based Vertebral Bone Quality Score for Prediction of Cage Subsidence and Screw Loosening in Patients Undergoing Degenerative Lumbar Surgery: A Meta-analysis
Neurospine. 2024;21(3):913-924.   Published online September 30, 2024
Close
Objective
Poor bone quality is a risk factor for postoperative complications after degenerative lumbar fusion surgery. The magnetic resonance imaging-based vertebral bone quality (VBQ) score is a good tool for assessing bone quality, and this is the first meta-analysis performed to summarize the predictive value of the VBQ score for cage subsidence and screw loosening in patients undergoing degenerative lumbar surgery.
Methods
Studies were comprehensively searched in electronic databases. The quality of the studies was assessed. The pooled sensitivity, specificity and summary receiver operating characteristic curve were calculated. Publication bias was assessed and meta-regression was conducted.
Results
We ultimately included 9 studies with a total of 1,404 patients with a mean age of 60.4 years and a percentage of females of 57.0%. According to the QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies 2) tool to assess methodological quality, the quality of the included studies was relatively low and risks of bias might exist. Results showed that a high VBQ was significantly associated with cage subsidence and screw loosening, and risk factor analysis revealed that the merged odds ratio was 5.37 for cage subsidence and 3.87 for screw loosening. With a VBQ cutoff value of 3.34±0.45, the pooled sensitivity and specificity for the diagnosis of postoperative complications were 0.75 and 0.75, respectively, and the area under the curve was 0.82 (95% confidence interval, 0.78–0.85).
Conclusion
A high VBQ was associated with a high risk of cage subsidence and screw loosening in patients who underwent degenerative lumbar surgery. The VBQ score could be considered for identifying high-risk patients for further evaluation.

Citations

Citations to this article as recorded by  Crossref logo
  • Evaluation of MRI-Based Region-specific Vertebral Bone Quality Score for Bone Mineral Density in Lumbar Fusion Surgery
    Xuan Zhao, Wei Wang, Xiaolong Chen, Shibao Lu
    Global Spine Journal.2026; 16(5): 2070.     CrossRef
  • MRI-based pedicle bone quality score predicts cage subsidence following oblique lumbar interbody fusion
    Xiao Hu, Xingxiao Pu, Xiandi Wang, Chuan Luo, Liyu Ran, Xingrui Peng, Tianhang Xie, Jiancheng Zeng
    European Spine Journal.2026; 35(6): 3454.     CrossRef
  • A novel method of C-VBQ score and CT-HU as risk predictors for cage subsidence after short level ACDF
    Qiang Zhang, Zequn Zhang, Rongzhi Ma, Yuan Xue
    Scientific Reports.2026;[Epub]     CrossRef
  • Development and validation of an MRI-based musculoskeletal model for predicting pedicle screw loosening after lumbar fusion surgery: a multicenter study
    Xuan Zhao, Ranlv Zhu, Wei Wang, Xiaolong Chen, Chunde Li, Shibao Lu
    International Journal of Surgery.2026; 112(2): 2518.     CrossRef
  • Accuracy of Magnetic Resonance Imaging-Based Vertebral and Endplate Bone Quality in Predicting Cage Subsidence in Anterior Cervical Spine Surgery: A Systematic Review and Meta-Analysis
    Alexander Erick Purnomo, Aldi Nanda Kurniawan, Yang Yang Endro Arjuna, Jephtah Furano Lumban Tobing, Hendra Tjong
    Journal of Neurological Surgery Part A: Central European Neurosurgery.2026; 87(04): 273.     CrossRef
  • Knee-specific bone quality assessment for cementless total knee arthroplasty candidate selection: a narrative review
    Dong Hwan Lee, Dai-Soon Kwak, Sheen-Woo Lee, Sung-Min Kim, Yong Deok Kim, In Jun Koh
    Knee Surgery & Related Research.2026;[Epub]     CrossRef
  • Predictive value of vertebral specificity of bone mineral density for cage subsidence among patients undergoing anterior cervical diskectomy and fusion: a retrospective study
    Xiaozhe Zhou, Ranxu Yang, Xiong Zhang, Yunsheng Wang, Wenshuai Li, Linfeng Wang
    European Spine Journal.2025; 34(6): 2207.     CrossRef
  • Endplate Hounsfield units outperform lumbar HU and VBQ in predicting cage subsidence after posterior lumbar interbody fusion: a retrospective cohort study
    Sheyang Xu, Xingling Liu, Xianglong Meng
    European Spine Journal.2025; 34(9): 4140.     CrossRef
  • Clinical Insights on Transforaminal Lumbar Interbody Fusion (TLIF) Implantations Following Spinal Fusion Surgery: Enhancing and Monitoring Bone Health in Patients
    Francesco Puglia, Marcello Ferraro, Valentina Longhi, Enrico Gallazzi, Giovanni Andrea La Maida
    Orthopedic Research and Reviews.2025; Volume 17: 281.     CrossRef
  • Accuracy of CT hounsfield units for predicting cage subsidence and pedicle screw loosening after lumbar interbody fusion: a systematic review and meta-analysis
    Alexander Erick Purnomo, Jephtah Furano Lumban Tobing, Aldi Nanda Kurniawan, Regan Elbert, Rivaldo Steven Heriyanto, Yang Yang Endro Arjuna
    Neurosurgical Review.2025;[Epub]     CrossRef
  • Predictive value of the VBQ score for internal fixation failure after PLIF and determinants of its cutoff value
    Jia-Yan Wu, Wen-Hao Hu, Zhi-Hao Ma, Ya-Wei Yao, Wen-Chao Wang, Ding-Fei Qian, Yi-Peng Cai, Fan-Qi Hu, Xue-Song Zhang
    Spine Research.2025; 1(3): 180.     CrossRef
  • 5,097 View
  • 160 Download
  • 11 Web of Science
  • 11 Crossref

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Effect of Cage Material and Size on Fusion Rate and Subsidence Following Biportal Endoscopic Transforaminal Lumbar Interbody Fusion
Neurospine. 2024;21(3):973-983.   Published online September 30, 2024
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Effect of Cage Material and Size on Fusion Rate and Subsidence Following Biportal Endoscopic Transforaminal Lumbar Interbody Fusion
Neurospine. 2024;21(3):973-983.   Published online September 30, 2024
Close
Objective
Biportal endoscopic transforaminal lumbar interbody fusion (BE-TLIF) is an emerging, minimally invasive technique performed under biportal endoscopic guidance. However, concerns regarding cage subsidence and sufficient fusion during BE-TLIF necessitate careful selection of an appropriate interbody cage to improve surgical outcomes. This study compared the fusion rate, subsidence, and other radiographic parameters according to the material and size of the cages used in BE-TLIF.
Methods
In this retrospective cohort study, patients who underwent single-segment BE-TLIF between April 2019 and February 2023 were divided into 3 groups: group A, regular-sized three-dimensionally (3D)-printed titanium cages; group B, regular-sized polyetheretherketone cages; and group C, large-sized 3D-printed titanium cages. Radiographic parameters, including lumbar lordosis, segmental lordosis, anterior and posterior disc heights, disc angle, and foraminal height, were measured before and after surgery. The fusion rate and severity of cage subsidence were compared between the groups.
Results
No significant differences were noted in the demographic data or radiographic parameters between the groups. The fusion rate on 1-year postoperative computed tomography was comparable between the groups. The cage subsidence rate was significantly lower in group C than in group A (41.9% vs. 16.7%, p=0.044). The severity of cage subsidence was significantly lower in group C (0.93±0.83) than in groups A (2.20±1.84, p=0.004) and B (1.79±1.47, p=0.048).
Conclusion
Cage materials did not affect the 1-year postoperative outcomes of BE-TLIF; however, subsidence was markedly reduced in large cages. Larger cages may provide more stable postoperative segments.

Citations

Citations to this article as recorded by  Crossref logo
  • Development and Validation of a Predictive Model and Web-Based Calculator for Cage Subsidence After Midline Lumbar Interbody Fusion (MIDLIF) Surgery
    Mingzheng Zhao, Honghao Yang, Shixuan Guo, Jun Miao, Zepei Zhang, Yangpu Zhang, Kuan Li, Fengqi Cheng, Jing Su, Yaoshen Zhang, Yong Hai, Yuzeng Liu
    Global Spine Journal.2026; 16(3): 1423.     CrossRef
  • Influence of surgical technique, interbody characteristics, and radiographic parameters on fusion rates across the disc space and posterolateral elements following transforaminal lumbar interbody fusion
    Zach Pennington, Abdelrahman Hamouda, Omar Hafz, Anthony L. Mikula, Michelle J. Clarke, William E. Krauss, Brett A. Freedman, Melvin D. Helgeson, Ahmad N. Nassr, Arjun S. Sebastian, Jeremy L. Fogelson, Benjamin D. Elder
    Clinical Neurology and Neurosurgery.2026; 261: 109285.     CrossRef
  • Sagittal Alignment and Clinical Outcomes After Biportal Endoscopic Transforaminal Lumbar Interbody Fusion Using a Single Expandable Cage: One Year Follow-up
    Sub-Ri Park, Namhoo Kim, Ji-Won Kwon, Kyung-Soo Suk, Hak-Sun Kim, Seong-Hwan Moon, Si-Young Park, Byung Ho Lee, Jae-Won Shin, Jin-Oh Park
    World Neurosurgery.2026; 205: 124698.     CrossRef
  • Advancements in unilateral biportal endoscopic lumbar interbody fusion: a narrative review
    Penghui Lv, Lu Li, Sichao Cheng, Jincheng Bai, Jianjun Chang
    European Journal of Medical Research.2026;[Epub]     CrossRef
  • A Review of Synthetic Bone Grafts in Lumbar Interbody Fusion
    Jaden Wise, Isabella Merem, Dahlia Wrubluski, Xuanzong Zhang, Ridge Weston, Min Shi, Maohua Lin, Frank D. Vrionis
    Bioengineering.2026; 13(3): 262.     CrossRef
  • Clinical and radiologic outcomes of expandable versus static cages in biportal endoscopic TLIF: focus on endplate injury and subsidence
    Tae Hoon Kang, Geumho Lee, Byungjun Kang, Jeongwoon Han, Hyun-jin Park, Minjoon Cho, Jae Hyup Lee
    Journal of Orthopaedic Surgery and Research.2026;[Epub]     CrossRef
  • En bloc discectomy via anterior lumbar approach: a technical note
    Harmantya Mahadhipta, Amri Muhyi, Muhamad Abdul Harist Fadhlizain, Mitchel Mitchel, Karina Sylvana Gani, Erica Kholinne
    SICOT-J.2026; 12: 19.     CrossRef
  • Clinical outcomes and radiologic parameters of percutaneous endoscopic posterior/transforaminal lumbar interbody fusion using rammed-earth technique
    Qingyang Kang, Zhilin Ge, Jiheng Zhan, Xuzhou Li, Guanwei Huang, Guoyi Su
    Frontiers in Surgery.2026;[Epub]     CrossRef
  • Titanium-coated PEEK versus 3D-printed porous titanium cages in transforaminal lumbar interbody fusion: A meta-analysis
    Youngmin Yu, Thomas Cho, Jiayong Liu
    Journal of Orthopaedics.2026; 77: 124.     CrossRef
  • Clinical and radiological outcomes following biportal endoscopic lumbar interbody fusion: A comparative study of three interbody cage strategies
    Ju-Eun Kim, Hee Soo Kim, Daniel K. Park
    World Neurosurgery: X.2026; 31: 100604.     CrossRef
  • Clinical and Radiological Outcomes of Double-Cage Full Endoscopic Transforaminal Lumbar Interbody Fusion Compared with Posterior Lumbar Interbody Fusion : A Retrospective Cohort Study
    Chi Ho Kim, Pius Kim, Chang Il Ju, Jong Hun Seo
    Journal of Korean Neurosurgical Society.2026; 69(4): 596.     CrossRef
  • Preoperative coronal magnetic resonance imaging: a critical evaluation of the Kambin’s triangle for the transforaminal lumbar interbody fusion procedure
    Koopong Siribumrungwong, Bunyaporn Wuttiworawanit, Punnawit Pinitchanon, Chanon Chiarnpattanodom, Thongchai Suntharapa
    Asian Spine Journal.2026;[Epub]     CrossRef
  • Impact of endplate–graft geometric matching on cage subsidence following stand-alone lateral lumbar interbody fusion: a finite element analysis
    Youchen Ye, Hao Li, Fangcai Li
    BMC Musculoskeletal Disorders.2026;[Epub]     CrossRef
  • 3D-printed porous titanium vs polyetheretherketone cages in lumbar interbody fusion: a prospective, multicenter, randomized controlled trial with bone mineral density stratification
    Jae-Won Shin, Mun-Su Park, Ji-Won Kwon, Sang-Ho Kim, Joonoh Seo, Hak-Sun Kim, Kyung-Soo Suk, Seong Hwan Moon, Si-Young Park, Byung Ho Lee
    The Spine Journal.2026;[Epub]     CrossRef
  • Technical Feasibility and Early Outcomes of Minimally Invasive Transforaminal Lumbar Interbody Fusion with Large-Footprint Cage via Tubular Approach: A Novel Surgical Technique
    Ayush Sharma, Shubham Kadam, Nandan Marathe, Avi Rangala, Sourav L. Das, Ajit Rampure
    Asian Journal of Neurosurgery.2026;[Epub]     CrossRef
  • Biportal Endoscopic Lumbar Interbody Fusion With 3D Printed Double Cage
    Ju-Eun Kim, Hee-Soo Kim, Sung Choi, Daniel K. Park
    Clinical Spine Surgery.2026;[Epub]     CrossRef
  • Risk factors influencing cage retropulsion following lumbar interbody fusion in treating degenerative lumbar diseases: A comprehensive systematic review and meta-analysis
    Yong Liu, Hongyu Chen, Xiaoming Hu, Xiaokun Wu, Xiangui Yu, Hai Chen, Wenxiong Zhang, Limin Du
    Journal of Orthopaedic Science.2025; 30(5): 768.     CrossRef
  • Anterior Lumbar Interbody Fusion (ALIF) Versus Full-Endoscopic/Percutaneous TLIF With a Large-Footprint Interbody Cage: A Comparative Observational Study
    Christian Morgenstern, Francisco Nogueras, Geoffrey Delbos, Rudolf Morgenstern
    Global Spine Journal.2025; 15(6): 2910.     CrossRef
  • Goutallier grading of psoas major and lumbar extensor muscles as a predictor of cage subsidence and reoperation following transforaminal and posterior lumbar interbody fusion
    Frank Vazquez, Alex Tang, Ara Khoylyan, Tan Chen
    The Spine Journal.2025; 25(11): 2514.     CrossRef
  • In vitro comparison of endplate preparation in biportal endoscopic and microscopic tubular transforaminal lumbar interbody fusion procedures
    Min-Seok Kang, Samuel K. Cho, Samuel Q. Li, Fady Y. Hijji, Jun S. Kim, Sang-Min Park, Ki-Han You, Hyun-Jin Park
    The Spine Journal.2025; 25(10): 2326.     CrossRef
  • Development and internal validation of a risk score for subsidence of expandable spacers in transforaminal lumbar interbody fusion (TLIF) surgery
    Martin N. Stienen, Lorenzo Bertulli, Linda Bättig, Yesim Yildiz, Gregor Fischer, Laurin Feuerstein, Francis Kissling, Thomas Schöfl, Felix C. Stengel, Felix Corr, Silvio Heinig, Nader Hejrati, Daniele Gianoli, Stefan Motov, Michael Betz, Benjamin Martens
    Brain and Spine.2025; 5: 104322.     CrossRef
  • Novel Unilateral Biportal Endoscopy-Assisted Lumbar Fusion With Dual Hybrid Cage Insertion: A Technical Note With Case Presentation
    Jisoo Ha, Kuldeep Bansal, Chang-Wook Kim, Do-Hyoung Kim, Shreenidhi Kulkarni, Hee-Don Han
    Journal of Minimally Invasive Spine Surgery and Technique.2025; 10(2): 230.     CrossRef
  • A Novel Switching Portal Technique in Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: Technical Notes and Comparative Outcomes
    Yun-Da Li, Chi-An Luo, Yung-Hsueh Hu, Wen-Chien Chen, Tsung-Ting Tsai, Po-Liang Lai, Tsai-Sheng Fu
    World Neurosurgery.2025; 203: 124511.     CrossRef
  • Biportal Endoscopic Lumbar Interbody Fusion Using the Oblique Lumbar Interbody Fusion Cage: Technical Note and Case Illustration
    Tran Vu Hoang Duong, Phan Quang Son, Le Tan Bao, Luc Dinh Phuong, Phan Dinh Thanh
    Journal of Minimally Invasive Spine Surgery and Technique.2025; 10(2): 303.     CrossRef
  • Anterior Cervical Discectomy and Fusion Using Cages With Different Sized Windows
    Chengkun Zhao, Shijie Wang, Jingjing Zhang, Hegang Niu, Yun Cao, Hui Tao, Cailiang Shen, Yinshun Zhang
    Spine.2025; 50(22): 1556.     CrossRef
  • Comparative Clinical and Radiological Outcomes of Banana-Shaped Versus Straight Cages in Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: A Retrospective Cohort Study
    Nguyen Ngoc Thoi, Nguyen Le Hoang Tuan, Le Tuong Vien, Nguyen Thanh Nhan, Hoang Nguyen Anh Tuan, Nguyen Van Thanh, Tran Nguyen Phuong, Bui Hong Thien Khanh
    Journal of Minimally Invasive Spine Surgery and Technique.2025; 10(2): 172.     CrossRef
  • Radiographic Analysis of Endplate Coverage of a 3-Dimensional-Expandable Transforaminal Lumbar Interbody Fusion (TLIF) Implant Compared to Static TLIF and Anterior Lumbar Interbody Fusion Implants
    Jacob Mazza, Manhal Siddiqi, John Paul G. Kolcun, Dominick Richards, Richard G. Fessler
    Neurospine.2025; 22(4): 891.     CrossRef
  • 9,875 View
  • 233 Download
  • 26 Web of Science
  • 27 Crossref

Minimally Invasive Spinal Surgery SMISS-Neurospine Special Issue

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The Change of Spinal Canal According to Oblique Lumbar Interbody Fusion in Degenerative Spondylolisthesis: A Prospective Observational Study
Neurospine. 2022;19(3):492-500.   Published online May 13, 2022
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The Change of Spinal Canal According to Oblique Lumbar Interbody Fusion in Degenerative Spondylolisthesis: A Prospective Observational Study
Neurospine. 2022;19(3):492-500.   Published online May 13, 2022
Close
Objective
Oblique lumbar interbody fusion (OLIF) involves inserting large cages into the interbody disc space. This expands the spinal canal and neural foramen by stretching the ligament flavum and releasing the facet joint, resulting in indirect neural decompression. Our objective was to investigate the changes in the spinal canal and ligament flavum over time after OLIF.
Methods
This was a prospective observational study involving 30 patients who underwent OLIF L4–5 between 2015 and 2018. In total, 27 of the 30 patients underwent preoperative, early follow-up ( < 5 days), and late follow-up (10–14 months) magnetic resonance imaging to measure the area of the spinal canal and ligament flavum. Based on the results, the patients were divided into subsidence and nonsubsidence groups for further analysis.
Results
After OLIF, the spinal canal area gradually increased during the preoperative, early postoperative, and late postoperative periods (p < 0.001). The thickness and area of the ligament flavum decreased gradually over the same periods (p < 0.001). Low-grade subsidence (2–4.4 mm) did not influence the effects on the spinal canal and ligament.
Conclusion
After OLIF, the spinal canal and ligament flavum gradually change, which is effective for indirect neural decompression. In addition, the effects of low-grade subsidence on the remodeling of the spinal canal and ligament flavum are insignificant.

Citations

Citations to this article as recorded by  Crossref logo
  • Is Congenital Lumbar Spinal Canal Stenosis a Contraindication for Indirect Decompression by Lateral Lumbar Interbody Fusion (LLIF)?
    Weerasak Singhatanadgige, Thada Nashinoros, Teerachat Tanasansomboon, Wicharn Yingsakmongkol, Vit Kotheeranurak, Worawat Limthongkul
    Global Spine Journal.2026; 16(5): 2117.     CrossRef
  • Oblique Lateral Interbody Fusion With Lateral Vertebral Screw Fixation Versus Transforaminal Lumbar Interbody Fusion for Severe Lumbar Stenosis: Results of a Multicenter Randomized Controlled Trial
    Xuefeng Li, Cheng Lin, Tangyiheng Chen, Renjie Li, Dapeng Li, Sheng Song, Huilin Yang, Genlei Chu, Weimin Jiang, Yijie Liu
    Neurosurgery.2026;[Epub]     CrossRef
  • Factors affecting outcomes of indirect decompression after oblique and lateral lumbar interbody fusions
    Kyle M M Behrens, Hossein Elgafy
    World Journal of Orthopedics.2025;[Epub]     CrossRef
  • Incidence and Risk Factors of Postoperative Ileus in Oblique Lumbar Interbody Fusion Surgery: A Retrospective Study
    Young-Seok Lee, Myeong Jin Ko, Seung Won Park
    Neurospine.2025; 22(1): 222.     CrossRef
  • Reduction-First Technique of Unilateral Biportal Endoscopy Lumbar Interbody Fusion for Spondylolisthesis
    JinWoo Jung, Man-Kyu Park, Yong Jin Park, Dae-Chul Cho, Young San Ko
    World Neurosurgery.2025; 198: 124005.     CrossRef
  • Efficacy observation of oblique lateral interbody fusion (OLIF) in treating severe spinal stenosis
    Yiliya Yilihamu, Jun Mo, Zhanjun Ma, Jianjiang Li, Yifei Huang
    BMC Surgery.2025;[Epub]     CrossRef
  • Improved intervertebral fusion in LLIF rabbit model with a novel titanium cage
    Jiaqi Li, Bingyi Zhao, Weijian Wang, Yafei Xu, Haoyu Wu, Wei Zhang
    The Spine Journal.2024; 24(6): 1109.     CrossRef
  • A Comprehensive Analysis of Potential Complications after Oblique Lumbar Interbody Fusion : A Review of Postoperative Magnetic Resonance Scans in Over 400 Cases
    Kang-Hoon Lee, Su-Hun Lee, Jun-Seok Lee, Young-Ha Kim, Soon-Ki Sung, Dong-Wuk Son, Sang-Weon Lee, Geun-Sung Song
    Journal of Korean Neurosurgical Society.2024; 67(5): 550.     CrossRef
  • Intraoperative Facet Joint Block Reduces Pain After Oblique Lumbar Interbody Fusion
    Sung Hyeon Noh, Sang-Woo Lee, Jong-moon Hwang, JinWoo Jung, Eunyoung Lee, Dae-Chul Cho, Chi Heon Kim, Kyoung-Tae Kim
    Journal of Bone and Joint Surgery.2024;[Epub]     CrossRef
  • Postoperative urinary retention after oblique lumbar interbody fusion under the systematic management protocol
    Joonsoo Lim, Jangyeob Lim, Asfandyar Khan, Chang-Hyun Lee, Jun-Hoe Kim, Sejin Choi, Tae-Shin Kim, Yunhee Choi, Chun Kee Chung, Sangwook T. Yoon, Kyoung-Tae Kim, Chi Heon Kim
    Scientific Reports.2024;[Epub]     CrossRef
  • Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion
    Su Hun Lee, Dong Wuk Son, Sung Hyun Bae, Jun Seok Lee, Young Ha Kim, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
    Neurospine.2023; 20(2): 553.     CrossRef
  • Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With Lumbar Degenera
    Xiangyu Zhang, Yutian Wang, Weikang Zhang, Shaocheng Liu, Zhenlei Liu, Kai Wang, Hao Wu
    Neurospine.2023; 20(2): 536.     CrossRef
  • Commentary on “Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion”
    Alexander E. Ropper
    Neurospine.2023; 20(2): 564.     CrossRef
  • Letter to the Editor : Classifying the Anatomical Location of the Ureter after Retroperitoneal Dissection
    Su-Hun Lee, Dong-Wuk Son, Jun-Seok Lee, Geun-Sung Song
    Journal of Korean Neurosurgical Society.2023; 66(5): 605.     CrossRef
  • Surgical treatment of spondylolisthesis by oblique lumbar interbody fusion and transpedicular screw fixation: Comparison between conventional double position versus navigation-assisted single lateral position
    Junghoon Han, Chang-Min Ha, Woon Tak Yuh, Young San Ko, Jun-Hoe Kim, Tae-Shin Kim, Chang-Hyun Lee, Sungjoon Lee, Sun-Ho Lee, Asfandyar Khan, Chun Kee Chung, Chi Heon Kim, Mohamed El-Sayed Abdel-Wanis
    PLOS ONE.2023; 18(9): e0291114.     CrossRef
  • The Influence of Spondylolisthesis Reduction on the Adjacent Lumbar Segment
    Tae-Hwan Park, Yunhee Choi, Tae-Shin Kim, Jun-Hoe Kim, Chang-Hyun Lee, Sum Kim, Young Rak Kim, Yong San Ko, Woon Tak Yuh, John M. Rhee, Kyoung-Tae Kim, Chun Kee Chung, Chi Heon Kim
    The Nerve.2023; 9(2): 91.     CrossRef
  • Fusion Assessment of Oblique Lumbar Interbody Fusion Using Demineralized Bone Matrix: A 2-Year Prospective Study
    Sangseok Lee, Jin Woo Jung, Sang-Woo Lee, Kyoung-Tae Kim, Heum-Dai Kwon, Subum Lee, Young San Ko, Pius Kim, Dae-Chul Cho
    Neurospine.2023; 20(4): 1205.     CrossRef
  • An Expanded Surgical Corridor of Oblique Lateral Interbody Fusion at L4–5: A Magnetic Resonance Imaging Study
    Worawat Limthongkul, Pakawas Praisarnti, Teerachat Tanasansomboon, Natavut Prasertkul, Vit Kotheeranurak, Wicharn Yingsakmongkol, Weerasak Singhatanadgige
    Neurospine.2023; 20(4): 1450.     CrossRef
  • 8,232 View
  • 327 Download
  • 17 Web of Science
  • 18 Crossref

Clinical Articles

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Stand-Alone Cages for Anterior Cervical Fusion: Are There No Problems?
Korean J Spine. 2016;13(1):13-19.   Published online March 31, 2016
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Stand-Alone Cages for Anterior Cervical Fusion: Are There No Problems?
Korean J Spine. 2016;13(1):13-19.   Published online March 31, 2016
Close
Objective

There are complications in stand-alone cage assisted anterior cervical discectomy and fusion (ACDF), such as cage subsidence and kyphosis. Here we report our clinical result on ACDF, comparing with stand-alone cages and with cervical plate system for degenerative cervical spine diseases.

Methods

Patients with degenerative cervical disease who were diagnosed and treated in Konyang University Hospital between January 2004 and December 2014 were included in this study. Patients who had operation in single level ACDF were selected. Patients scored the degree of pain using visual analog scale before and after the surgery. Subsidence was defined as ≥3-mm decrease of the segmental height, and cervical kyphosis was defined as progression of ≥5° at 12 months after postoperative follow-up compared to that measured at the immediate postoperative period.

Results

A total of 81 patients were enrolled for this study. Forty-five patients were included in a cervical plate group and the others were in stand-alone cage group. There was no statistical difference in pain score between the 2 groups. Segmental subsidence was observed in 7 patients (15.6%) in plate-assisted cervical fusion group, and 13 patients (36.1%) in stand-alone cage group. Segmental kyphosis was observed in 4 patients (8.9%) in plate-assisted cervical fusion group, and 10 patients (27.8%) in stand-alone cage group. There was statistical difference between the 2 groups.

Conclusion

There was no difference in pain between 2 groups. But stand-alone case group showed higher incidence rate than plate-assisted cervical fusion group in segmental subsidence and cervical kyphosis. When designing cervical fusion, more attention should be given selecting the surgical technique.

Citations

Citations to this article as recorded by  Crossref logo
  • Level specific hounsfield unit thresholds as a predictor of subsidence following transforaminal and posterior lumbar interbody fusion
    Mina Girgis, Frank L. Vazquez, Alex Tang, Arpitha Pamula, Russell G. Strom, Tan Chen
    Journal of Orthopaedic Reports.2026; 5(3): 100764.     CrossRef
  • Reoperation Risk Between Plated and Stand-Alone Anterior Cervical Discectomy and Fusion
    Ehsan Tabaraee, Heather A. Prentice, Jessica E. Harris, Verain Mahajan, Ravinder Bains, Alem Yacob, Calvin C. Kuo, Allen L. Ho, Elizabeth P. Norheim, Omid R. Hariri, Kern H. Guppy
    Spine.2026; 51(3): 170.     CrossRef
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Radiologic Changes of Anterior Cervical Discectomy and Fusion Using Allograft and Plate Augmentation: Comparison of Using Fixed and Variable Type Screw
Korean J Spine. 2013;10(3):160-164.   Published online September 30, 2013
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Radiologic Changes of Anterior Cervical Discectomy and Fusion Using Allograft and Plate Augmentation: Comparison of Using Fixed and Variable Type Screw
Korean J Spine. 2013;10(3):160-164.   Published online September 30, 2013
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Objective

To evaluate radiologic result of anterior cervical discectomy and fusion with allobone graft and plate augmentation, and the change of radiologic outcome between screw type and insertion angle.

Methods

Retrospective review of clinical and radiological data of 29 patients. Segmental angle, height and screw angles were measured and followed. The fusion rate was assessed by plain radiography and CT scans. We divided the patients into two groups according to screw type and angles. Group A: fixed screw, Group B: variable screw. Interscrew angle was measured between most upper and lower screws with Cobb's methods.

Results

Overall fusion rate was 86.2% on plain radiography. Fusion was also assessed by CT scan and Bridwell's grading system. There was no difference in fusion and subsidence rates between two groups. Subsidence was found in 5 patients (17.2%). Segmental lordotic angle was increased from preoperative status and maximized at the immediate postoperative period and then reduced at 1 year follow up. Segmental height showed similar increase and decrease values.

Conclusion

ACDF with allograft and plate showed favorable fusion rates, and the screw type and angle did not affect results of surgery.

Citations

Citations to this article as recorded by  Crossref logo
  • Could the Type of Allograft Used for Anterior Cervical Discectomy and Fusion Affect Surgical Outcome? A Comparison Between Cortical Ring Allograft and Cortico-Cancellous Allograft
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    Clinics in Orthopedic Surgery.2025; 17(2): 238.     CrossRef
  • Standalone cage versus anchored cage for anterior cervical discectomy and fusion: a comparative analysis of clinical and radiological outcomes
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    International Orthopaedics.2022; 46(10): 2339.     CrossRef
  • Comparison between selective caudal fixed screw construct and all variable screw construct in anterior cervical discectomy and fusion
    Jae Jun Yang, Sehan Park, Seongyun Park
    Scientific Reports.2021;[Epub]     CrossRef
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    Kathryn-Anne Jimenez, Jihyeon Kim, Jaenam Lee, Hwan-Mo Lee, Seong-Hwan Moon, Kyung-Soo Suk, Hak-Sun Kim, Byung-Ho Lee
    Journal of Clinical Medicine.2021; 10(9): 2034.     CrossRef
  • Anterior cervical discectomy and fusion: Techniques, complications, and future directives
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  • Comparison of Cortical Ring Allograft and Plate Fixation with Autologous Iliac Bone Graft for Anterior Cervical Discectomy and Fusion
    Jae Chul Lee, Hae-Dong Jang, Joonghyun Ahn, Sung-Woo Choi, Deokwon Kang, Byung-Joon Shin
    Asian Spine Journal.2019; 13(2): 258.     CrossRef
  • Comparison of Outcomes for Anterior Cervical Discectomy and Fusion With and Without Anterior Plate Fixation
    Jeremie D. Oliver, Sandy Goncalves, Panagiotis Kerezoudis, Mohammed Ali Alvi, Brett A. Freedman, Ahmad Nassr, Mohamad Bydon
    Spine.2018; 43(7): E413.     CrossRef
  • A Prospective Study with Cage-Only or Cage-with-Plate Fixation in Anterior Cervical Discectomy and Interbody Fusion of One and Two Levels
    Sam Yeol Kim, Seung Hwan Yoon, Dokeun Kim, Chang Hyun Oh, Seyang Oh
    Journal of Korean Neurosurgical Society.2017; 60(6): 691.     CrossRef
  • Anterior cervical discectomy and fusion with a compressive staple of C-JAWS
    Lei Xia, Ming-Xing Liu, Jun Zhong, Jin Zhu, Ning-Ning Dou, Massimiliano Visocchi
    British Journal of Neurosurgery.2016; 30(6): 649.     CrossRef
  • Surgical Outcome of a Zero-profile Device Comparing with Stand-alone Cage and Anterior Cervical Plate with Iliac Bone Graft in the Anterior Cervical Discectomy and Fusion
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Clinical Results from Subsidence and Loss of Lordosis after Anterior Cervical Discectomy and Fusion.
Korean J Spine. 2009;6(3):138-143.
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Clinical Results from Subsidence and Loss of Lordosis after Anterior Cervical Discectomy and Fusion.
Korean J Spine. 2009;6(3):138-143.
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OBJECT: The aim of this study is to analyze the statistical significance between the clinical result and subsidence and lordosis loss after anterior cervical discectomy and interbody fusion operation for degenerative cervical disc diseases.
METHODS
From January 2004 to December 2006, retrospective study of 82 patients with symptomatic degenerative cervical disc disease who underwent anterior cervical discectomy and interbody fusion using the PEEK SolisTM cage and the carbon composite Osta-PekTM cage with autologous bone graft was done. Mean follow-up period was 13.2 months. Clinical results were assessed by bone fusion, subsidence, segmental lordosis loss and Odom's criteria.
RESULTS
Of the 82 patients, single level fusion was accomplished in 67 patients and two-level fusion in 15 patients. Total accomplished fusion level was 97: C3/4 in 9 levels, C4/5 in 29 levels, C5/6 in 37 levels, C6/7 in 21 levels, C7/T1 in 1 level. 9 patients fit into complete resolved, 59 improved and 14 not changed, thus the success rate in clinical outcome was 82.9%. Bone fusion was successfully confirmed in the total of 82 patients. The height of disc space was decreased to 2.13+/-2.16mm: 2.64+/-1.81mm in the Osta-PekTM cage, 2.44+/-1.36mm in the PEEK SolisTM cage. The Osta-PekTM cage provided higher subsidence tendency than the PEEK SolisTM cage in our study. However, there was no statistical significance between the two cage groups. The subsidence and lordosis loss showed poor clinical outcome, but there was no statistical significance.
CONCLUSIONS
There were no significant differences between the Osta-PekTM cage and PEEK SolisTM cage on clinical outco mes. Both cages showed low subsidences and lordosis loss with good fusion rate and clinical outcome.
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Comparison between Carbon Fiber Composite Frame and PEEK(Polyetheretherketone) Cages in the Efficiency of Interbody Fusion for Surgical Treatment of Cervical Disc Diseases.
Korean J Spine. 2010;7(1):10-16.
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Comparison between Carbon Fiber Composite Frame and PEEK(Polyetheretherketone) Cages in the Efficiency of Interbody Fusion for Surgical Treatment of Cervical Disc Diseases.
Korean J Spine. 2010;7(1):10-16.
Close
OBJECTIVE
To evaluate the efficiency of carbon fiber composite frame and polyetheretherketone(PEEK) cages in the interbody fusion for surgical treatment of cervical disc diseases, we analyzed fusion time and subsidence rate.
METHODS
From March 2004 to February 2007 fifty patients with cervical disc diseases underwent anterior discectomy and interbody fusion in 60 levels. The subjects were 26 men and 24 women with a mean age of 57.2 years ranging from 29 to 67. Among them 25 patients underwent operations using carbon fiber composite frame cages (Osta-Pek(R), Co-Ligne, Zurich, Switzerland) in 30 levels, and 25 patients using PEEK cages(Cornerstone(R), Medtronic, TN, USA) in 30 levels. The cages were packed with allograft bone or bone substitute(demineralised bone matrix). On lateral flexion-extension radiographs anterior disc height and posterior disc height were measured at preoperative time, postoperative 1, 3, 6 and 12 month respectively. Segmental stability(lordotic angle) was measured at postoperative 3, 6, and 12 months in all 60 levels for fusion time.
RESULTS
The anterior disc height and posterior disc height were 4.87+/-1.36mm and 3.25+/-0.73mm at preoperative time, 7.32+/-1.41mm and 4.77+/-0.80mm at postoperative 1month, and 5.87+/-1.47mm and 3.22+/-0.93mm at posto- perative 12 months respectively in carbon fiber composite frame cage group(30 levels). The anterior disc height and posterior disc height were 4.88+/-1.18mm and 3.75+/-0.75mm at preoperative time, 7.26+/-1.17mm and 5.27+/-0.55mm at postoperative 1month, and 6.23+/-1.16mm and 3.96+/-0.69mm at postoperative 12months respectively in PEEK cage group(30 levels). The angular motion at the fused segment was measured in carbon fiber composite frame cage and PEEK group for segmental stability(two degrees or less flexion-extension range of motion at the fusion site). The carbon fiber composite frame cage group was stabilized between postoperative 3 months and 6 months, but PEEK cage group was stabilized between 6 months and 9 months. This result was statistically significant(p-value =0.003)(Fig. 2). Fusion rate of carbon composite frame cage group was 28%, 67% and 83% at 3, 6, 12 months after operation, and that of PEEK cage group was 24%, 48% and 86% at postoperative 3, 6 and 12 months respe- ctively. Complications included transient hoarseness, cage migration and subsidence. There was no persistent hoar- seness or Horner syndrome. We have observed severe subsidence(above 3mm) in two cases(6.7%) of carbon fiber composite frame cage group only. Anterior cage migration was shown in each one case(3.3%) of carbon fiber composite frame and PEEK cage group.
CONCLUSION
The carbon fiber composite frame cage group showed a tendency of earlier fusion than PEEK cage group but both cages were same in the fusion rate at postoperative 1 year. But, restoration or maintenance of inter- vertebral height was much better in PEEK cage group than carbon fiber composite frame cage group. Subsidence rate was higher in carbon fiber cage group rather than PEEK cage group.
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