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Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.
The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Essay

December 31, 2020


History of Spinal Neurosurgery and Spine Societies
Mehmet Zileli, Salman Sharif, Maurizio Fornari, Premenand Ramani, Fengzeng Jian, Richard Fessler, Se-Hoon Kim, Toshihiro Takami, Nobuyuki Shimokawa, Gilbert Dechambenoit, et al.
Neurospine. 2020;17(4):675-694.

Essay

December 31, 2020


The Art of Diagnosis in the Cervical Spine
Melvin C. Makhni, Caleb M. Yeung, K. Daniel Riew
Neurospine. 2020;17(4):695-703.

Review Article

December 31, 2020


Early Management of Cervical Spine Trauma: WFNS Spine Committee Recommendations
Mehmet Zileli, Enrique Osorio-Fonseca, Nikolay Konovalov, Carlos Cardenas-Jalabe, Stanislav Kaprovoy, Sergey Mlyavykh, Artur Pogosyan
Neurospine. 2020;17(4):710-722.

Epidemiology, prevention, early management of cervical spine trauma and it's reduction are the objectives of this review paper. A PubMed and MEDLINE search between 2009 and 2019 were conducted using...

Review Article

December 31, 2020


Upper Cervical Spine Trauma: WFNS Spine Committee Recommendations
Oscar L. Alves, Leopoldina Pereira, Se-Hoon Kim, Andrey Grin, Nobuyuki Shimokawa, Nikolay Konovalov, Mehmet Zileli
Neurospine. 2020;17(4):723-736.

Craniovertebral junction (CVJ) trauma is a challenging clinical condition. Being a highly mobile functional unit at the junction of the skull and the vertebral column, traumatic events in this area...

Review Article

December 31, 2020


Subaxial Cervical Spine Injuries: WFNS Spine Committee Recommendations
Salman Sharif, Muhammad Yassar Jazaib Ali, Ibet Marie Y. Sih, Jutty Parthiban, Óscar L. Alves
Neurospine. 2020;17(4):737-758.

To formulate specific guidelines for the recommendation of subaxial cervical spine injuries concerning classification, management, posttraumatic locked facets and vertebral artery injury. Computerized literature was searched on PubMed and google...

Review Article

December 31, 2020


Early Management of Spinal Cord Injury: WFNS Spine Committee Recommendations
José Antonio Soriano Sánchez, Salman Sharif, Francesco Costa, Jose Alberto Israel Romero Rangel, Carla Daniela Anania, Mehmet Zileli
Neurospine. 2020;17(4):759-784.

Scientific knowledge today is being generated more rapidly than we can assimilate thus requiring continuous review of gold-standards for diagnosis and treatment of specific pathologies. The aim of this paper...

Review Article

December 31, 2020


Pharmacologic and Regenerative Cell Therapy for Spinal Cord Injury: WFNS Spine Committee Recommendations
Toshihiro Takami, Nobuyuki Shimokawa, Jutty Parthiban, Mehmet Zileli, Sheena Ali
Neurospine. 2020;17(4):785-796.

This is a review article examining the pharmacologic and regenerative cell therapy for spinal cord injury. A literature search during last 10 years were conducted using key words. Case reports,...

Review Article

December 31, 2020


Pediatric Cervical Spine Injuries and SCIWORA: WFNS Spine Committee Recommendations
Nikolay Konovalov, Nikolay Peev, Mehmet Zileli, Salman Sharif, Stanislav Kaprovoy, Stanislav Timonin
Neurospine. 2020;17(4):797-808.

Cervical trauma in children have variations from the adults mainly due to anatomic differences. An optimal diagnostic and treatment strategy is critical, particularly when there is a lack of standardized...

Review Article

December 31, 2020


Outcomes of Spinal Cord Injury: WFNS Spine Committee Recommendations
Jutty Parthiban, Mehmet Zileli, Salman Yousuf Sharif
Neurospine. 2020;17(4):809-819.

This comprehensive review article aims to provide some definitive statements on the factors like clinical syndromes, radiological findings, and decompressive surgery, that may influence the outcomes in cervical spinal cord...

Review Article

December 31, 2020


Rehabilitation of Spinal Cord Injury: WFNS Spine Committee Recommendations
Nikolay Peev, Alexander Komarov, Enrique Osorio-Fonseca, Mehmet Zileli
Neurospine. 2020;17(4):820-832.

Spinal cord injury (SCI) is accompanied by a significant number of complications associated with damage to the spinal cord, gross functional impairments leading to limited self-care and movement, leading to...

Review Article

December 31, 2020


Cervical Deformity: Evaluation, Classification, and Surgical Planning
Ahilan Sivaganesan, Justin S. Smith, Han Jo Kim
Neurospine. 2020;17(4):833-842.

Cervical deformity is a challenging condition to treat and requires complex decision-making. Apart from a thorough history and physical examination, a thoughtful and quantitative analysis of multiple imaging modalities is...

Original Article

December 31, 2020


Weak Ligaments and Sloping Joints: A New Hypothesis for Development of Congenital Atlantoaxial Dislocation and Basilar Invagination
Avnish K. Chauhan, P. Sarat Chandra, Nishant Goyal, Madhumita R. Chowdhury, Jyotirmoy Banerjee, Manjari Tripathi, Madhulika Kabra
Neurospine. 2020;17(4):843-856.

Objective: Developmental bony craniovertebral junction (CVJ) anomalies seem to have a genetic basis and also abnormal joint morphology causing atlantoaxial dislocation (AAD) and basilar invagination (BI). Methods: DNA extracted polymerase chain...

Original Article

December 31, 2020


Longitudinal Evaluation of Patient-Reported Outcomes Measurement Information System for Back and Leg Pain in Minimally Invasive Transforaminal Lumbar Interbody Fusion
Nathaniel W. Jenkins, James M. Parrish, Nadia M. Hrynewycz, Thomas S. Brundage, Kern Singh
Neurospine. 2020;17(4):862-870.

Objective: While visual analogue score (VAS) metrics are among the most universally adopted patient-reported outcome measures (PROMs), there is limited research on the influence of back and leg pain on...

Original Article

December 31, 2020


Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
Anoop R. Galivanche, Raj Gala, Preetpaul S. Bagi, Arianne J. Boylan, Christopher M. Dussik, Pedro D. Coutinho, Jonathan N. Grauer, Arya G. Varthi
Neurospine. 2020;17(4):871-878.

Objective: To compare the perioperative morbidity of 2-level anterior cervical discectomy and fusion (ACDF) with that of 1-level anterior cervical corpectomy and fusion (ACCF) for the treatment of cervical degenerative...

Original Article

December 31, 2020


Chronic Opioid Use Following Lumbar Discectomy: Prevalence, Risk Factors, and Current Trends in the United States
Andrew B. Harris, Bo Zhang, Majd Marrache, Varun Puvanesarajah, Micheal Raad, Hamid Hassanzadeh, Mark Bicket, Amit Jain
Neurospine. 2020;17(4):879-887.

Objective: Lumbar discectomy is commonly performed for symptomatic lumbar disc herniation. We aimed to examine prescribing patterns and risk factors for chronic opioid use following lumbar discectomy. Methods: Using a private...

Original Article

December 31, 2020


Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis
Lauren K. Dunn, Ching-Jen Chen, Davis G. Taylor, Kamilla Esfahani, Brian Brenner, Charles Luo, Thomas J. Buell, Sarah N. Spangler, Avery L. Buchholz, Justin S. Smith, et al.
Neurospine. 2020;17(4):888-895.

Objective: This was a retrospective, cohort study investigating the efficacy and safety of continuous low-dose postoperative tranexamic acid (PTXA) on drain output and transfusion requirements following adult spinal deformity surgery. Methods:...

Original Article

December 31, 2020


Synthetic Cages Associated With Increased Rates of Revision Surgery and Higher Costs Compared to Allograft in ACDF in the Nonelderly Patient
Majd Marrache, Rachel Bronheim, Andrew B. Harris, Varun Puvanesarajah, Micheal Raad, Sang Lee, Richard Skolasky, Amit Jain
Neurospine. 2020;17(4):896-901.

Objective: The aim of this study was to compare all-cause reoperation rates and costs in nonelderly patients treated with anterior cervical discectomy and fusion (ACDF) with structural allograft versus synthetic...

Original Article

December 31, 2020


Selection of the Lowest Instrumented Vertebra and Relative Odds Ratio of Distal Adding-on for Lenke Type 1A and 2A Curves in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis
Che-Wei Liu, Lawrence G. Lenke, Lee A. Tan, Taemin Oh, Kou-Hua Chao, Shi-Ding Lin, Ru-Yu Pan
Neurospine. 2020;17(4):902-909.

Objective: To examine existing literature and pool the data to determine the relative odds ratio of “adding-on” (AO) based on various reported criteria for lower instrumented vertebra (LIV) selection in...

Original Article

December 31, 2020


Methods and Early Clinical Results of Percutaneous Lumbar Interbody Fusion
Shu Nakamura, Fjio Ito, Zenya Ito, Motohide Shibayama
Neurospine. 2020;17(4):910-920.

Objective: Percutaneous lumbar interbody fusion (PELIF) is a procedure that includes the use of new devices, which allow minimally invasive diskectomy under the percutaneous full-endoscopic guidance and safe percutaneous insertion...

Original Article

December 31, 2020


Feasibility of the Far Lateral Suboccipital Approach to the Retroodontoid Region. How Much Bone Removal Is Truly Needed?
Gergely Bodon, Kristof Kiraly, Tamas Ruttkay, Bernhard Hirt, Heiko Koller
Neurospine. 2020;17(4):921-928.

Objective: The posterolateral extradural suboccipital approach can be used to reach the anterior epidural space and the retro-odontoid regions. The extent of necessary bone removal of the atlas vertebra (C1)...

Technical Note

December 31, 2020


Transforaminal Endoscopic Discectomy for Large, Two Level Calcified, Thoracic Disc Herniations With 5-Year Follow-up
Karlo Houra, Robert Saftic
Neurospine. 2020;17(4):954-959.

To describe technical details and benefits of transforaminal endoscopic discectomy for treatment of patients with large, dorsomedial, calcified thoracic disc herniations at 2 levels and to report on their clinical...
Current Issue
Volume 17(4); Dec 2020
A Neurospine Surgeon With the Mind of a Neuroscientist: Makoto Taniguchi, MD, PhD (1958–2020)
Phyo Kim
Neurospine. 2020;17(4):673-674.

Editorial

December 31, 2020
History of Spinal Neurosurgery and Spine Societies
Mehmet Zileli, Salman Sharif, Maurizio Fornari, Premenand Ramani, Fengzeng Jian, Richard Fessler, Se-Hoon Kim, Toshihiro Takami, Nobuyuki Shimokawa, Gilbert Dechambenoit, et al.
Neurospine. 2020;17(4):675-694.

Essay

December 31, 2020
The Art of Diagnosis in the Cervical Spine
Melvin C. Makhni, Caleb M. Yeung, K. Daniel Riew
Neurospine. 2020;17(4):695-703.

Essay

December 31, 2020
Cervical Spine Trauma and Spinal Cord Injury Recommendations of WFNS Spine Committee
Mehmet Zileli, Nikolay Konovalov, Salman Sharif
Neurospine. 2020;17(4):704-707.

Introduction

December 31, 2020
Finding a Better Way to Manage Cervical Spine Trauma and Spinal Cord Injury
Se-Hoon Kim
Neurospine. 2020;17(4):708-709.

Editorial

December 31, 2020
Early Management of Cervical Spine Trauma: WFNS Spine Committee Recommendations
Mehmet Zileli, Enrique Osorio-Fonseca, Nikolay Konovalov, Carlos Cardenas-Jalabe, Stanislav Kaprovoy, Sergey Mlyavykh, Artur Pogosyan
Neurospine. 2020;17(4):710-722.

Review Article

December 31, 2020
Upper Cervical Spine Trauma: WFNS Spine Committee Recommendations
Oscar L. Alves, Leopoldina Pereira, Se-Hoon Kim, Andrey Grin, Nobuyuki Shimokawa, Nikolay Konovalov, Mehmet Zileli
Neurospine. 2020;17(4):723-736.

Review Article

December 31, 2020
Subaxial Cervical Spine Injuries: WFNS Spine Committee Recommendations
Salman Sharif, Muhammad Yassar Jazaib Ali, Ibet Marie Y. Sih, Jutty Parthiban, Óscar L. Alves
Neurospine. 2020;17(4):737-758.

Review Article

December 31, 2020
Early Management of Spinal Cord Injury: WFNS Spine Committee Recommendations
José Antonio Soriano Sánchez, Salman Sharif, Francesco Costa, Jose Alberto Israel Romero Rangel, Carla Daniela Anania, Mehmet Zileli
Neurospine. 2020;17(4):759-784.

Review Article

December 31, 2020
Pharmacologic and Regenerative Cell Therapy for Spinal Cord Injury: WFNS Spine Committee Recommendations
Toshihiro Takami, Nobuyuki Shimokawa, Jutty Parthiban, Mehmet Zileli, Sheena Ali
Neurospine. 2020;17(4):785-796.

Review Article

December 31, 2020
Pediatric Cervical Spine Injuries and SCIWORA: WFNS Spine Committee Recommendations
Nikolay Konovalov, Nikolay Peev, Mehmet Zileli, Salman Sharif, Stanislav Kaprovoy, Stanislav Timonin
Neurospine. 2020;17(4):797-808.

Review Article

December 31, 2020
Outcomes of Spinal Cord Injury: WFNS Spine Committee Recommendations
Jutty Parthiban, Mehmet Zileli, Salman Yousuf Sharif
Neurospine. 2020;17(4):809-819.

Review Article

December 31, 2020
Rehabilitation of Spinal Cord Injury: WFNS Spine Committee Recommendations
Nikolay Peev, Alexander Komarov, Enrique Osorio-Fonseca, Mehmet Zileli
Neurospine. 2020;17(4):820-832.

Review Article

December 31, 2020
Cervical Deformity: Evaluation, Classification, and Surgical Planning
Ahilan Sivaganesan, Justin S. Smith, Han Jo Kim
Neurospine. 2020;17(4):833-842.

Review Article

December 31, 2020
Weak Ligaments and Sloping Joints: A New Hypothesis for Development of Congenital Atlantoaxial Dislocation and Basilar Invagination
Avnish K. Chauhan, P. Sarat Chandra, Nishant Goyal, Madhumita R. Chowdhury, Jyotirmoy Banerjee, Manjari Tripathi, Madhulika Kabra
Neurospine. 2020;17(4):843-856.

Original Article

December 31, 2020
Commentary on “Weak Ligaments and Sloping Joints: A New Hypothesis for Development of Congenital Atlantoaxial Dislocation and Basilar Invagination”
Lingbo Kong
Neurospine. 2020;17(4):857-858.

Editorial

December 31, 2020
From Anatomic to Genetic Understanding of Developmental Craniovertebral Junction Abnormalities
Alexander E. Ropper
Neurospine. 2020;17(4):859-861.

Editorial

December 31, 2020
Longitudinal Evaluation of Patient-Reported Outcomes Measurement Information System for Back and Leg Pain in Minimally Invasive Transforaminal Lumbar Interbody Fusion
Nathaniel W. Jenkins, James M. Parrish, Nadia M. Hrynewycz, Thomas S. Brundage, Kern Singh
Neurospine. 2020;17(4):862-870.

Original Article

December 31, 2020
Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
Anoop R. Galivanche, Raj Gala, Preetpaul S. Bagi, Arianne J. Boylan, Christopher M. Dussik, Pedro D. Coutinho, Jonathan N. Grauer, Arya G. Varthi
Neurospine. 2020;17(4):871-878.

Original Article

December 31, 2020
Chronic Opioid Use Following Lumbar Discectomy: Prevalence, Risk Factors, and Current Trends in the United States
Andrew B. Harris, Bo Zhang, Majd Marrache, Varun Puvanesarajah, Micheal Raad, Hamid Hassanzadeh, Mark Bicket, Amit Jain
Neurospine. 2020;17(4):879-887.

Original Article

December 31, 2020
Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis
Lauren K. Dunn, Ching-Jen Chen, Davis G. Taylor, Kamilla Esfahani, Brian Brenner, Charles Luo, Thomas J. Buell, Sarah N. Spangler, Avery L. Buchholz, Justin S. Smith, et al.
Neurospine. 2020;17(4):888-895.

Original Article

December 31, 2020
Synthetic Cages Associated With Increased Rates of Revision Surgery and Higher Costs Compared to Allograft in ACDF in the Nonelderly Patient
Majd Marrache, Rachel Bronheim, Andrew B. Harris, Varun Puvanesarajah, Micheal Raad, Sang Lee, Richard Skolasky, Amit Jain
Neurospine. 2020;17(4):896-901.

Original Article

December 31, 2020
Selection of the Lowest Instrumented Vertebra and Relative Odds Ratio of Distal Adding-on for Lenke Type 1A and 2A Curves in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis
Che-Wei Liu, Lawrence G. Lenke, Lee A. Tan, Taemin Oh, Kou-Hua Chao, Shi-Ding Lin, Ru-Yu Pan
Neurospine. 2020;17(4):902-909.

Original Article

December 31, 2020
Methods and Early Clinical Results of Percutaneous Lumbar Interbody Fusion
Shu Nakamura, Fjio Ito, Zenya Ito, Motohide Shibayama
Neurospine. 2020;17(4):910-920.

Original Article

December 31, 2020
Feasibility of the Far Lateral Suboccipital Approach to the Retroodontoid Region. How Much Bone Removal Is Truly Needed?
Gergely Bodon, Kristof Kiraly, Tamas Ruttkay, Bernhard Hirt, Heiko Koller
Neurospine. 2020;17(4):921-928.

Original Article

December 31, 2020
Cervical Arthroplasty in the Treatment of Cervical Angina: Case Report and Review of the Literature
Omar M. Al Jammal, Luis Daniel Diaz-Aguilar, Shanmukha Srinivas, Jillian Plonsker, Ronald Sahyouni, Martin H. Pham
Neurospine. 2020;17(4):929-938.

Case Report

December 31, 2020
Cervical Angina
Lee A. Tan
Neurospine. 2020;17(4):939-940.

Editorial

December 31, 2020
Management of Pseudarthrosis With Implant Failure at a Multilevel Vertebral Column Resection Site: A Case Report
Venkat Boddapati, Joseph M. Lombardi, Lawrence G. Lenke
Neurospine. 2020;17(4):941-946.

Case Report

December 31, 2020
Arteriovenous Fistula at the Craniocervical Junction Found After Cervical Laminoplasty for Ossification of the Posterior Longitudinal Ligament
Susumu Sasada, Masafumi Hiramatsu, Akira Kusumegi, Haruto Fujimura, Shogo Oshikata, Yuichi Takahashi, Kenki Nishida, Takao Yasuhara, Isao Date
Neurospine. 2020;17(4):947-953.

Case Report

December 31, 2020
Transforaminal Endoscopic Discectomy for Large, Two Level Calcified, Thoracic Disc Herniations With 5-Year Follow-up
Karlo Houra, Robert Saftic
Neurospine. 2020;17(4):954-959.

Technical Note

December 31, 2020
A Submandibular Retropharyngeal Approach Improves Surgical Exposure
Henri Salle, François Caire
Neurospine. 2020;17(4):960-962.

Letter to the Editor

December 31, 2020
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