Neurospine

Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.

The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Review Article

March 31, 2023

Anterior Endoscopic Cervical Discectomy: Surgical Technique and Literature Review

Yong Ahn

Neurospine. 2023;20(1):11-18.

The conventional surgical technique for radiculopathy with cervical disc herniation (CDH) is anterior cervical discectomy and fusion, with a good clinical outcome and fusion rate. However, significant perioperative morbidity related...

Review Article

March 31, 2023

Uniportal, Transforaminal Endoscopic Thoracic Discectomy: Review and Technical Note

Sang Hun Lee, Farah N. Musharbash

Neurospine. 2023;20(1):19-27.

Symptomatic thoracic disc herniations are a rare entity and their operative treatment is challenging. Open approaches, despite providing excellent access, are associated with significant access morbidity from thoracotomy, and this...

Review Article

March 31, 2023

Perioperative Management for Full-Endoscopic Lumbar Discectomy: Consideration From the Perspective of Preventing Complication

Takeshi Hara, Yukoh Ohara

Neurospine. 2023;20(1):28-32.

In recent years, full-endoscopic discectomy (FED) has expanded its range of indications with the development of devices and various techniques. The advantage of FED over conventional surgery is that it...

Review Article

March 31, 2023

Current Indications for Spinal Endoscopic Surgery and Potential for Future Expansion

Kuo-Tai Chen, Jin-Sung Kim, Abel Po-Hao Huang, Martin Hsiu-Chu Lin, Chien-Min Chen

Neurospine. 2023;20(1):33-42.

Endoscopic spine surgery (ESS) has evolved as a safe, effective, and efficient alternative for minimally invasive spine surgery (MISS). The innovation of full-endoscopic systems makes definitive decompression surgery through different...

Review Article

March 31, 2023

The Role and Future of Endoscopic Spine Surgery: A Narrative Review

Hyungjoo Kwon, Jeong-Yoon Park

Neurospine. 2023;20(1):43-55.

Many types of surgeries are changing from conventional to minimally invasive techniques. Techniques in spine surgery have also changed, with endoscopic spine surgery (ESS) becoming a major surgical technique. Although...

Review Article

March 31, 2023

Complications and Management of Endoscopic Spinal Surgery

Chang Il Ju, Seung Myung Lee

Neurospine. 2023;20(1):56-77.

In the past, the use of endoscopic spine surgery was limited to intervertebral discectomy; however, it has recently become possible to treat various spinal degenerative diseases, such as spinal stenosis...

Original Article

March 31, 2023

Biportal Endoscopic Transforaminal Lumbar Interbody Fusion Using Double Cages: Surgical Techniques and Treatment Outcomes

Jwo-Luen Pao

Neurospine. 2023;20(1):80-91.

Objective: To describe the surgical techniques and the treatment outcomes of biportal endoscopic transforaminal lumbar interbody fusion (BETLIF) using double cages. Methods: This study included 89 patients with 114 fusion segments...

Original Article

March 31, 2023

Biportal Endoscopic Posterior Cervical Foraminotomy for Adjacent 2-Level Foraminal Lesions Using a Single Approach (Sliding Technique)

Dong Hwa Heo, Ji Soo Ha, Jae Won Jang

Neurospine. 2023;20(1):92-98.

Objective: Endoscopic posterior cervical foraminotomy (PCF) using uniportal or biportal endoscopic approach has been performed for cervical foraminal stenosis or foraminal disc herniation. Two-level PCF is possible using a single...

Original Article

March 31, 2023

Spinal Canal Remodeling and Indirect Decompression of Contralateral Foraminal Stenosis After Endoscopic Posterolateral Transforaminal Lumbar Interbody Fusion

Pang Hung Wu, Eugene Tze-Chun Lau, Hyeun-Sung Kim, Giovanni Grasso, Il-Tae Jang

Neurospine. 2023;20(1):99-109.

Objective: There is a lack of literature on indirect decompression in uniportal endoscopic posterolateral transforaminal lumbar interbody fusion (EPTLIF). Our aim is to evaluate the dimensions of the spinal canal...

Original Article

March 31, 2023

The Use of Dual Direction Expandable Titanium Cage With Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: A Technical Consideration With Preliminary Results

Don Young Park, Dong Hwa Heo

Neurospine. 2023;20(1):110-118.

Objective: Expandable cage technology has emerged for lumbar interbody fusion to restore intervertebral disc space height and alignment through a narrow surgical corridor. The purpose of this study is to...

Original Article

March 31, 2023

Endoscopic and Nonendoscopic Approaches to Single-Level Lumbar Spine Decompression: Propensity Score-Matched Comparative Analysis and Frailty-Driven Predictive Model

Alexander J. Kassicieh, Kavelin Rumalla, Aaron C. Segura, Syed Faraz Kazim, John Vellek, Meic H. Schmidt, Peter C. Shin, Christian A. Bowers

Neurospine. 2023;20(1):119-128.

Objective: The endoscopic spine surgery (ESS) approach is associated with high levels of patient satisfaction, shorter recovery time, and reduced complications. The present study reports multicenter, international data, comparing ESS...

Original Article

March 31, 2023

Biportal Endoscopic Posterior Thoracic Laminectomy for Thoracic Spondylotic Myelopathy Caused by Ossification of the Ligamentum Flavum: Technical Developments and Outcomes

Ji Yeon Kim, Ji Soo Ha, Chang Kyu Lee, Dong Chan Lee, Hyun Jin Hong, Su Yong Choi, Choon Keun Park

Neurospine. 2023;20(1):129-140.

Objective: Advanced biportal endoscopic surgery techniques can be used to treat thoracic myelopathy secondary to ossification of the ligamentum flavum (OLF). This case series elaborates on a feasible biportal endoscopic...

Original Article

March 31, 2023

Navigation-Assisted Full-Endoscopic Radiofrequency Rhizotomy Versus Fluoroscopy-Guided Cooled Radiofrequency Ablation for Sacroiliac Joint Pain Treatment: Comparative Study

Chien-Min Chen, Jae Hwan Lee, Meng-Yin Yang, Shang-Wun Jhang, Kai-Sheng Chang, Su-Wei Ou, Li-Wei Sun, Kuo-Tai Chen

Neurospine. 2023;20(1):141-149.

Objective: Sacroiliac joint (SIJ) pain is a common cause of chronic low back pain. Full-endoscopic rhizotomy of lateral branches of dorsal rami innervating SIJ is a potential option for patients’...

Review Article

March 31, 2023

Activating Endogenous Neurogenesis for Spinal Cord Injury Repair: Recent Advances and Future Prospects

Haiyang Yu, Shangbin Yang, Haotao Li, Rongjie Wu, Biqin Lai, Qiujian Zheng

Neurospine. 2023;20(1):164-180.

After spinal cord injury (SCI), endogenous neural stem cells are activated and migrate to the injury site where they differentiate into astrocytes, but they rarely differentiate into neurons. It is...

Review Article

March 31, 2023

Reduction of Lower Cervical Facet Dislocation: A Review of All Techniques

Ke Liu, Zhengfeng Zhang

Neurospine. 2023;20(1):181-204.

Objective: The surgical treatment of lower cervical facet dislocation is controversial. Great advancements on reduction techniques for lower cervical facet dislocation have been made in the past decades. However, there...

Review Article

March 31, 2023

The Incidence, Changes and Treatments of Cervical Deformity After Infection and Inflammation

Bo Han, Jianqiang Wang, Yong Hai, Duan Sun, Weishi Liang, Peng Yin, Hongtao Ding

Neurospine. 2023;20(1):205-220.

A healthy cervical spine with normal movement is the basis of many daily activities and is essential for maintaining a good quality of life. However, the alignment, fusion, and structure...

Review Article

March 31, 2023

Concepts and Techniques to Prevent Cervical Spine Deformity After Spine Surgery: A Narrative Review

Robert K. Merrill, John C. Clohisy, Todd J. Albert, Sheeraz A. Qureshi

Neurospine. 2023;20(1):221-230.

Adult cervical spine deformity is associated with decreased health-related quality of life, disability, and myelopathy. A number of radiographic parameters help to characterize cervical deformity and aid in the diagnosis...

Original Article

March 31, 2023

Clinical Characteristics and Treatment Outcomes of Long-Level Intramedullary Spinal Cord Tumors: A Consecutive Series of 43 Cases

Dongao Zhang, Tao Fan, Wayne Fan, Xingang Zhao, Cong Liang, Yinqian Wang, Kun Wu

Neurospine. 2023;20(1):231-239.

Objective: Long-level intramedullary spinal cord tumors (LIMSCTs) cause complex treatment issues. However, LIMSCTs have rarely been analyzed separately. The authors reported a large case series of LIMSCTs and analyzed the...

Original Article

March 31, 2023

The Accuracy and Safety of a Pedicle Screw Using the Freehand Technique in Minimally Invasive Scoliosis Surgery

Yunjin Nam, Dong-Gune Chang, Hong Jin Kim, Young Ha Kim, Sangmin Lee, Jae Hyuk Yang, Seung Woo Suh

Neurospine. 2023;20(1):240-247.

Objective: The safety and clinical usefulness of minimally invasive scoliosis surgery (MISS) has been reported in various studies. However, freehand pedicle screwing in MISS remains technically challenging. The purpose of...

Original Article

March 31, 2023

The Prediction of Neurological Prognosis for Cervical Spondylotic Myelopathy Using Diffusion Tensor Imaging

Soichiro Takamiya, Motoyuki Iwasaki, Takumi Yokohama, Daisuke Oura, Yoshimasa Niiya, Miki Fujimura

Neurospine. 2023;20(1):248-254.

Objective: Although cervical spondylotic myelopathy (CSM) can be easily diagnosed using magnetic resonance imaging (MRI), prediction of surgical effect using preoperative radiological examinations remains difficult. In previous studies, it was...

Original Article

March 31, 2023

Risk Factors of Postoperative Cerebrospinal Fluid Leak After Craniovertebral Junction Anomalies Surgery: A Case-Control Study

Yu Xiao, Bing Wang, Yulian Chen, Lingqiang Chen, Zhenkai Lou, Zhiqiang Gong

Neurospine. 2023;20(1):255-264.

Objective: To identify potential risk factors for cerebrospinal fluid (CSF) leakage after craniovertebral junction (CVJ) anomaly surgery and to provide a reference for clinical practice. Methods: Sixty-six patients who underwent elective...

Original Article

March 31, 2023

Predicting Mechanical Complications After Adult Spinal Deformity Operation Using a Machine Learning Based on Modified Global Alignment and Proportion Scoring With Body Mass Index and Bone Mineral Density

Sung Hyun Noh, Hye Sun Lee, Go Eun Park, Yoon Ha, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Sang Hyun Kim, et al.

Neurospine. 2023;20(1):265-274.

Objective: This study aimed to create an ideal machine learning model to predict mechanical complications in adult spinal deformity (ASD) surgery based on GAPB (modified global alignment and proportion scoring...

Original Article

March 31, 2023

The Rehabilitation-Related Effects on the Fear, Pain, and Disability of Patients With Lumbar Fusion Surgery: A Systematic Review and Meta-Analysis

Haiyan Cheng, Jing Liu, Lin Shi, Xiuxiu Hei

Neurospine. 2023;20(1):278-289.

Objective: The lumbar fusion is an important surgery for the orthopedic diseases. The rehabilitation might improve the outcome of patients with lumbar fusion surgery. The rehabilitation-related effects can be revealed...

Original Article

March 31, 2023

Weekend Admission Increases Risk of Readmissions Following Elective Cervical Spinal Fusion

Renee Ren, Calista Dominy, Brian Bueno, Sara Pasik, Jonathan Markowitz, Brandon Yeshoua, Brian Cho, Varun Arvind, Aly A. Valliani, Jun Kim, et al.

Neurospine. 2023;20(1):290-300.

Objective: The “weekend effect” occurs when patients cared for during weekends versus weekdays experience worse outcomes. But reasons for this effect are unclear, especially amongst patients undergoing elective cervical spinal...

Original Article

March 31, 2023

Pelvic Incidence–Lumbar Lordosis Mismatch Is Predisposed to Adjacent Segment Degeneration After Single-Level Anterior Lumbar Interbody Fusion: A Retrospective Case-Control Study

Sun Geon Yoon, Hyung Chang Lee, Sang-Min Lee

Neurospine. 2023;20(1):301-307.

Objective: Spinopelvic parameters play important roles in clinical outcomes and disability after short-segment fusion surgery for degenerative spine disease. This study aimed to investigate the relationship between preoperative or postoperative...

Original Article

March 31, 2023

Comparison of Cortical Bone Trajectory to Pedicle-Based Dynamic Stabilization: An Analysis of 291 Patients

Chih-Chang Chang, Hsuan-Kan Chang, Chin-Chu Ko, Ching-Lan Wu, Yi-Hsuan Kuo, Tsung-Hsi Tu, Wen-Cheng Huang, Jau-Ching Wu

Neurospine. 2023;20(1):308-316.

Objective: Pedicle-based dynamic stabilization (DS) has gained popularity outside of America. Although pedicle screw (PS) loosening has always been a concern, it is reportedly innocuous. Cortical bone trajectory (CBT) screw...

Original Article

March 31, 2023

Carbon Fiber-Reinforced Polyetheretherketone Spinal Implants for Treatment of Spinal Tumors: Perceived Advantages and Limitations

Christopher Alvarez-Breckenridge, Romulo de Almeida, Ali Haider, Matthew Muir, Justin Bird, Robert North, Laurence Rhines, Claudio Tatsui

Neurospine. 2023;20(1):317-326.

Purpose: Carbon-fiber reinforced polyetheretherketone (CFRP)-based spinal implants are an alternative to titanium, offering less image artifact as their metallic counterparts while maintaining similar biomechanical and biocompatibility properties. Its use in...

Original Article

March 31, 2023

Robotics in Cervical Spine Surgery: Feasibility and Safety of Posterior Screw Placement

Lu-Ping Zhou, Zhi-Gang Zhang, Dui Li, Shu Fang, Rui Sheng, Ren-Jie Zhang, Cai-Liang Shen

Neurospine. 2023;20(1):329-339.

Objective: Robot-assisted (RA) techniques have been widely investigated in thoracolumbar spine surgery. However, the application of RA methods on cervical spine surgery is rare due to the complex morphology of...

Original Article

March 31, 2023

Pediatric Spinal Hemangioblastomas: Clinical Features and Surgical Outcomes of 39 Cases

Bo Han, Liang Zhang, Wenqing Jia

Neurospine. 2023;20(1):343-352.

Objective: Spinal hemangioblastomas (HBs) are a rare pathology, especially in the pediatric population. The natural history and long-term outcomes of pediatric patients with spinal HBs remain unclear due to their...

Original Article

March 31, 2023

Effectiveness of the Endplate Reduction Technique Combined With Bone Grafting for the Treatment of Thoracolumbar Fractures by Using Posterior Short-Segment Fixation

Jiguang Hou, Dong Ren, Yufeng Chen, Lindan Geng, Shuangquan Yao, Haotian Wu, Pengcheng Wang

Neurospine. 2023;20(1):353-364.

Objective: This study aimed to examine the effect of the endplate reduction (EPR) technique combined with bone grafting for treating thoracolumbar burst fractures using posterior short-segmental fixation. Methods: Patients with thoracolumbar...

Original Article

March 31, 2023

Facet Articular Irregularity Is the Most Relevant Risk Factor for Rapidly Progressive Degenerative Cervical Myelopathy

Yasuhiro Takeshima, Ai Okamoto, Shohei Yokoyama, Fumihiko Nishimura, Ichiro Nakagawa, Young-Soo Park, Hiroyuki Nakase

Neurospine. 2023;20(1):365-373.

Objective: Facet articular irregularity is associated with rapidly progressive degenerative cervical myelopathy (DCM). However, its significance compared with other known risk factors remains unknown. Therefore, this retrospective study aimed to...

Original Article

March 31, 2023

A 30-Year Worldwide Research Productivity of Scientific Publication in Full-Endoscopic Decompression Spine Surgery: Quantitative and Qualitative Analysis

Yanting Liu, Vit Kotheeranurak, Javier Quillo-Olvera, Van Isseldyk Facundo, Sagar Sharma, Siravich Suvithayasiri, Khanathip Jitpakdee, Guang-Xun Lin, Akaworn Mahatthanatrakul, Hussam Jabri, et al.

Neurospine. 2023;20(1):374-389.