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Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.
The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Review Article

March 31, 2020


Gene Therapy Approach for Intervertebral Disc Degeneration: An Update
Yoshiki Takeoka, Takashi Yurube, Kotaro Nishida
Neurospine. 2020;17(1):3-14.

Review Article

March 31, 2020


Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Review
Tibo Nico Emmie Volleman, Jordy Schol, Kosuke Morita, Daisuke Sakai, Masahiko Watanabe
Neurospine. 2020;17(1):19-35.

Original Article

March 31, 2020


Correlation of Early Outcomes and Intradiscal Interleukin-6 Expression in Lumbar Fusion Patients
John D. Koerner, Dessislava Z. Markova, Greg D. Schroeder, Christopher L. Antonacci, Joseph Mendelis, Alexander R. Vaccaro, D. Greg Anderson, Chris K. Kepler
Neurospine. 2020;17(1):36-41.

Original Article

March 31, 2020


Direct and Intervertebral DiscMediated Sensitization of Dorsal Root Ganglion Neurons by Hypoxia and Low pH
Junxuan Ma, Despina Stefanoska, Sibylle Grad, Mauro Alini, Marianna Peroglio
Neurospine. 2020;17(1):42-59.

Original Article

March 31, 2020


Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells
Nam Vo, Brandon Couch, Joon Lee, Gwendolyn Sowa, James Kang, Studer Rebecca
Neurospine. 2020;17(1):60-68.

Original Article

March 31, 2020


Rabbit Annulus Fibrosus Cells Express Neuropeptide Y, Which Is Influenced by Mechanical and Inflammatory Stress
Malcolm E. Dombrowski, Adam S. Olsen, Nicholas Vaudreuil, Brandon K. Couch, Qing Dong, Michelle Tucci, Joon Y. Lee, Nam V. Vo, Gwendolyn Sowa
Neurospine. 2020;17(1):69-76.

Original Article

March 31, 2020


Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype
Rahel D. May, Daniela A. Frauchiger, Christoph E. Albers, Willy Hofstetter, Benjamin Gantenbein
Neurospine. 2020;17(1):77-87.

Review Article

March 31, 2020


Robotic Spine Surgery and Augmented Reality Systems: A State of the Art
Gianluca Vadalà, Sergio De Salvatore, Luca Ambrosio, Fabrizio Russo, Rocco Papalia, Vincenzo Denaro
Neurospine. 2020;17(1):88-100.

Review Article

November 4, 2019


Biomaterials in Spinal Implants: A Review
Andrew Warburton, Steven J. Girdler, Christopher M. Mikhail, Amy Ahn, Samuel K. Cho
Neurospine. 2020;17(1):101-110.

Original Article

March 31, 2020


Telerobotic Spinal Surgery Based on 5G Network: The First 12 Cases
Wei Tian, Mingxing Fan, Cheng Zeng, Yajun Liu, Da He, Qi Zhang
Neurospine. 2020;17(1):114-120.

Original Article

March 31, 2020


Polyetheretherketone Versus Titanium Cages for Posterior Lumbar Interbody Fusion: Meta-Analysis and Review of the Literature
Elie Massaad, Nida Fatima, Ali Kiapour, Muhamed Hadzipasic, Ganesh M. Shankar, John H. Shin
Neurospine. 2020;17(1):125-135.

Original Article

April 12, 2019


Rigid-Plating and Cortico-Cancellous Allograft Are Effective for 3-Level Anterior Cervical Discectomy and Fusion: Radiographic and Clinical Outcomes
Philip K. Louie, Andrew C. Sexton, Danel D. Bohl, Ehsan Tabaraee, Steven M. Presciutti, Benjamin C. Mayo, Justin C. Paul, Comron Saifi, Howard S. An
Neurospine. 2020;17(1):146-155.

Original Article

July 5, 2019


Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
Chi Hyung Lee, Dong Wuk Son, Su Hun Lee, Jun Seok Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
Neurospine. 2020;17(1):156-163.

Original Article

July 9, 2019


Degenerative Cervical Myelopathy: A 7-Letter Coding System That Supports Decision-Making for the Surgical Approach
Luca Papavero, Gregor Schmeiser, Ralph Kothe, Bronek Boszczyk, Oliver Heese, Yoshiharu Kawaguchi, Anna MacDowall, Claes Olerud, Nikolaos Paidakakos, Anastasios Panagiotou, et al.
Neurospine. 2020;17(1):164-171.

Original Article

March 31, 2020


Effect of the Presence and Type of Plate Augmentation on Postoperative Dysphagia Among Adult Patients Undergoing Elective Anterior Cervical Discectomy and Fusion for Spondylosis: A Randomized Trial
Tom J. O’Donohoe, Lisa Mililli, Alison Magee, Christopher Thien, Yi Yuen Wang
Neurospine. 2020;17(1):174-183.

Original Article

February 5, 2020


Evaluation of Postoperative Mental Health Outcomes in Patients Based on Patient-Reported Outcome Measurement Information System Physical Function Following Anterior Cervical Discectomy and Fusion
Joon S. Yoo, Nathaniel W. Jenkins, James M. Parrish, Thomas S. Brundage, Nadia M. Hrynewycz, Franchesca A. Mogilevsky, Kern Singh
Neurospine. 2020;17(1):184-189.

Original Article

March 31, 2020


The Impact of Modic Changes on Preoperative Symptoms and Clinical Outcomes in Anterior Cervical Discectomy and Fusion Patients
James D. Baker, Garrett K. Harada, Youping Tao, Philip K. Louie, Bryce A. Basques, Fabio Galbusera, Frank Niemeyer, Hans-Joachim Wilke, Howard S. An, Dino Samartzis
Neurospine. 2020;17(1):190-203.

Original Article

March 31, 2020


Timing of Surgery in Tubular Microdiscectomy for Lumbar Disc Herniation and Its Effect on Functional Impairment Outcomes
Alessandro Siccoli, Marlies P. de Wispelaere, Marc L. Schröder, Victor E. Staartjes
Neurospine. 2020;17(1):204-212.

Original Article

March 31, 2020


The Influence of Mechanic Factors in Disc Degeneration Disease as a Determinant for Surgical Indication
Gulden Demirci Otluoğlu, Deniz Konya, Zafer Orkun Toktas
Neurospine. 2020;17(1):215-220.

Original Article

March 31, 2020


Image-Based Markers Predict Dynamic Instability in Lumbar Degenerative Spondylolisthesis
William Slikker III, Alejandro A. Espinoza Orías, Grant D. Shifflett, Joe Y.B. Lee, Krzysztof Siemionow, Sapan Gandhi, Louis Fogg, Dino Samartzis, Nozomu Inoue, Howard S. An
Neurospine. 2020;17(1):221-227.

Original Article

March 31, 2020


Less Opioid Consumption With Enhanced Recovery After Surgery Transforaminal Lumbar Interbody Fusion (TLIF): A Comparison to Standard Minimally-Invasive TLIF
Hsuan-Kan Chang, Meng Huang, Jau-Ching Wu, Wen-Cheng Huang, Michael Y. Wang
Neurospine. 2020;17(1):228-236.

Original Article

July 24, 2019


Use of Opioids and Other Analgesics Before and After Primary Surgery for Adult Spinal Deformity: A 10-Year Nationwide Study
Frederik Taylor Pitter, Matt Sikora, Martin Lindberg-Larsen, Alma Becic Pedersen, Benny Dahl, Martin Gehrchen
Neurospine. 2020;17(1):237-245.

Original Article

March 31, 2020


Opioids and Spinal Cord Stimulators: Pre- and Postoperative Opioid Use Patterns and Predictors of Prolonged Postoperative Opioid Use
Lawal Labaran, Jomar N.A. Aryee, Joshua Bell, Nikhil Jain, Varun Puvanesarajah, Michael Raad, Amit Jain, Jonathan Carmouche, Hamid Hassanzadeh
Neurospine. 2020;17(1):246-253.

Original Article

February 1, 2020


Comparison of the Safety and Effectiveness of Percutaneous Endoscopic Lumbar Discectomy for Treating Lumbar Disc Herniation Under Epidural Anesthesia and General Anesthesia
Zhiqiang Ren, Shenghua He, Jiao Li, Yeguang Wang, Juyi Lai, Zhitao Sun, Hualong Feng, Jian Wang
Neurospine. 2020;17(1):254-259.

Original Article

February 5, 2020


The Navigated Oblique Lumbar Interbody Fusion: Accuracy Rate, Effect on Surgical Time, and Complications
Zhuo Xi, Dean Chou, Praveen V. Mummaneni, Shane Burch
Neurospine. 2020;17(1):260-267.

Original Article

January 26, 2020


Lower Extremity Motor Deficits Are Underappreciated in Patient-Reported Outcome Measures: Added Value of Objective Outcome Measures
Martin Nikolaus Stienen, Nicolai Maldaner, Marketa Sosnova, Holger Joswig, Marco Vincenzo Corniola, Luca Regli, Gerhard Hildebrandt, Karl Schaller, Oliver Pascal Gautschi
Neurospine. 2020;17(1):270-280.

Original Article

October 15, 2019


A New Shielding Curtain for Protection of Intraoperative Radiation During Minimally Invasive Spine Surgery
Se Hoon Park, Myeong Jin Ko, Yong Sook Park, Jaehan Yun, Hongsik Byun, Seung Won Park
Neurospine. 2020;17(1):288-293.

Original Article

July 11, 2019


Re-examining the Spectrum of Lumbosacral Transitional Dysmorphisms: Quantifying Joint Asymmetries and Evaluating the Anatomy of Screw Fixation Corridors
Niladri Kumar Mahato
Neurospine. 2020;17(1):294-303.

Original Article

February 1, 2020


Oxford Cobbometer Versus Computer Assisted-Software for Measurement of Cobb Angle in Adolescent Idiopathic Scoliosis
Tarek Elfiky, Nirmal Patil, Mohamed Shawky, Ahmed Siam, Raafat Ragab, Yasser Allam
Neurospine. 2020;17(1):304-311.

Ossification of the Posterior Longitudinal Ligament in Cervical Spine: Prevalence, Management, and Prognosis
Jau-Ching Wu, Yu-Chun Chen, Wen-Cheng Huang
Neurospine. 2018;15(1):33-41.

Review Article

March 28, 2018

Health Care Burden of Spinal Diseases in the Republic of Korea: Analysis of a Nationwide Database From 2012 Through 2016
Chang-Hyun Lee, Chun Kee Chung, Chi Heon Kim, Ji-Woong Kwon
Neurospine. 2018;15(1):66-76.

Original Article

March 28, 2018

Feasibility of Full Endoscopic Spine Surgery in Patients Over the Age of 70 Years With Degenerative Lumbar Spine Disease
Jeong Hoon Kim, Hyeun Sung Kim, Ankur Kapoor, Nitin Adsul, Ki Joon Kim, Sung Ho Choi, Jee-Soo Jang, Il-Tae Jang, Seong-Hoon Oh
Neurospine. 2018;15(2):131-137.

Original Article

June 19, 2018

Minimally Invasive Spinal Surgery for Adult Spinal Deformity
Junseok Bae, Sang-Ho Lee
Neurospine. 2018;15(1):18-24.

Review Article

March 28, 2018

Superior and Middle Cluneal Nerve Entrapment as a Cause of Low Back Pain
Toyohiko Isu, Kyongsong Kim, Daijiro Morimoto, Naotaka Iwamoto
Neurospine. 2018;15(1):25-32.

Review Article

March 28, 2018

Differences in Cervical Sagittal Alignment Changes in Patients Undergoing Laminoplasty and Anterior Cervical Discectomy and Fusion
Su Hun Lee, Dong Wuk Son, Jun Seok Lee, Dong Ha Kim, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
Neurospine. 2018;15(1):91-100.

Original Article

March 28, 2018

Predicting Surgical Complications in Adult Patients Undergoing Anterior Cervical Discectomy and Fusion Using Machine Learning
Varun Arvind, Jun S. Kim, Eric K. Oermann, Deepak Kaji, Samuel K. Cho
Neurospine. 2018;15(4):329-337.

Original Article

December 17, 2018

The Option of Motion Preservation in Cervical Spondylosis: Cervical Disc Arthroplasty Update
Chih-Chang Chang, Wen-Cheng Huang, Jau-Ching Wu, Praveen V. Mummaneni
Neurospine. 2018;15(4):296-305.

Review Article

December 14, 2018

A Cost-Effectiveness Analysis of the Integration of Robotic Spine Technology in Spine Surgery
Richard Philip Menger, Amey R. Savardekar, Frank Farokhi, Anthony Sin
Neurospine. 2018;15(3):216-224.

Original Article

August 29, 2018

Evolution of Spinal Endoscopic Surgery
Manyoung Kim, Hyeun-Sung Kim, Sung Woon Oh, Nitin Maruti Adsul, Ravindra Singh, Osama Nezar Kashlan, Jung Hoon Noh, Il Tae Jang, Seong Hoon Oh
Neurospine. 2019;16(1):6-14.

Review Article

March 31, 2019

Choice of Rods in Surgical Treatment of Adolescent Idiopathic Scoliosis: What Are the Clinical Implications of Biomechanical Properties? – A Review of the Literature
Søren Ohrt-Nissen, Benny Dahl, Martin Gehrchen
Neurospine. 2018;15(2):123-130.

Review Article

June 19, 2018

Intra- and Interrater Reliability of Sagittal Spinopelvic Parameters on Full-Spine Radiographs in Adults With Symptomatic Spinal Disorders
Kati Kristiina Kyrölä, Järvenpää Salme, Järviluoma Tuija, Irmola Tero, Kauppinen Eero, Häkkinen Arja
Neurospine. 2018;15(2):175-181.

Original Article

June 19, 2018

Impact of Resident Involvement in Neurosurgery: An American College of Surgeons’ National Surgical Quality Improvement Program Database Analysis of 33,977 Patients
Andreea Seicean, Prateek Kumar, Sinziana Seicean, Duncan Neuhauser, Warren R. Selman, Nicholas C. Bambakidis
Neurospine. 2018;15(1):54-65.

Original Article

March 27, 2018

Effect of Myoarchitectonic Spinolaminoplasty on Concurrent Hypertension in Patients With Cervical Spondylotic Myelopathy
Kazushige Itoki, Ryu Kurokawa, Tetsuro Shingo, Phyo Kim
Neurospine. 2018;15(1):77-85.

Original Article

March 28, 2018

Spinal Epidermoid Tumors: Case Report and Review of the Literature
Vivek B. Beechar, Pascal O. Zinn, Kent A. Heck, Gregory N. Fuller, Inbo Han, Akash J. Patel, Alexander E. Ropper
Neurospine. 2018;15(2):117-122.

Review Article

June 19, 2018

Gender Differences in the Self-assessment of Quality of Life and Disability After Spinal Fusion for Chronic Low Back Pain at a Neurosurgical Center in Eastern Europe
Gheorghe Ungureanu, Alexandra Chitu, Ioana Iancu, Cristian Kakucs, Tiberiu Maior, Ioan Stefan Florian
Neurospine. 2018;15(3):261-268.

Original Article

August 29, 2018

Clinical Outcomes and Prognostic Factors in Patients With Myelopathy Caused by Thoracic Ossification of the Ligamentum Flavum
Jae-Kwang Kim, Hyun-Seung Ryu, Bong Ju Moon, Jung-Kil Lee
Neurospine. 2018;15(3):269-276.

Original Article

September 7, 2018

Review of Photoacoustic Imaging for Imaging-Guided Spinal Surgery
Seung Hee Han
Neurospine. 2018;15(4):306-322.

Review Article

November 19, 2018

Endoscopic Lumbar Surgery: The State of the Art in 2019
Alexander J. Butler, Milad Alam, Kevin Wiley, Alexander Ghasem, Augustus J. Rush III, Jeffrey C. Wang
Neurospine. 2019;16(1):15-23.

Review Article

March 31, 2019

Diversity in Surgical Decision Strategies for Adult Spine Deformity Treatment: The Effects of Neurosurgery or Orthopedic Training Background and Surgical Experience
Jiin Kang, Naobumi Hosogane, Christopher Ames, Frank Schwab, Robert Hart, Douglas Burton, Christopher Shaffrey, Justin S. Smith, Shay Bess, Virginie Lafage, et al.
Neurospine. 2018;15(4):353-361.

Original Article

August 29, 2018

Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and Fusion
Wenbo Lin, Alex Ha, Venkat Boddapati, Wen Yuan, K. Daniel Riew
Neurospine. 2018;15(3):194-205.

Invited Review

September 28, 2018

Lower Extremity Motor Deficits Are Underappreciated in Patient-Reported Outcome Measures: Added Value of Objective Outcome Measures
Martin Nikolaus Stienen, Nicolai Maldaner, Marketa Sosnova, Holger Joswig, Marco Vincenzo Corniola, Luca Regli, Gerhard Hildebrandt, Karl Schaller, Oliver Pascal Gautschi
Neurospine. 2020;17(1):270-280.

Original Article

January 26, 2020

A Review of a New Clinical Entity of ‘Central Atlantoaxial Instability’: Expanding Horizons of Craniovertebral Junction Surgery
Atul Goel
Neurospine. 2019;16(2):186-194.

Review Article

June 30, 2019

Degenerative Cervical Myelopathy; A Review of the Latest Advances and Future Directions in Management
Jamie R.F. Wilson, Jetan H. Badhiwala, Ali Moghaddamjou, Allan R. Martin, Michael G. Fehlings
Neurospine. 2019;16(3):494-505.

Review Article

August 26, 2019

The Effect of Recombinant Tyrosine Hydroxylase Expression on the Neurogenic Differentiation Potency of Mesenchymal Stem Cells
Gizem Turac, Gokhan Duruksu, Erdal Karaoz
Neurospine. 2018;15(1):42-53.

Original Article

March 28, 2018

Highly Accurate Analysis of the Cervical Neural Tract of the Elderly Using ZOOM DTI
Sho Furuya, Motoyuki Iwasaki, Takumi Yokohama, Daisuke Ohura, Tomoyuki Okuaki
Neurospine. 2018;15(2):169-174.

Original Article

June 19, 2018

Study of the Transverse Foramen in the Subaxial Cervical Spine in Korean Patients With Degenerative Changes: An Anatomical Note
Hridayesh Pratap Malla, Sung Bum Kim, Jun Sung Won, Man Kyu Choi
Neurospine. 2018;15(2):163-168.

Original Article

June 19, 2018

Fixed and Variable Relationship Models to Define the Volume-Value Relationship in Spinal Fusion Surgery: A Macroeconomic Analysis Using Evidence-Based Thresholds
Sergio M. Navarro, William Case Frankel, Heather S. Haeberle, Prem N. Ramkumar
Neurospine. 2018;15(3):249-260.

Original Article

September 6, 2018

Cervical Open-Door Laminoplasty by Hydroxyapatite Implant Insertion Without Suturing
Yoshifumi Kawanabe, Motoaki Fujimoto, Tsukasa Sato
Neurospine. 2018;15(4):362-367.

Original Article

October 7, 2018

A Randomized Controlled Trial of Fluoroscopically-Guided Sacroiliac Joint Injections: A Comparison of the Posteroanterior and Classical Oblique Techniques
Gaurav Chauhan, Prabhdeep Hehar, Vivek Loomba, Aman Upadhyay
Neurospine. 2019;16(2):317-324.

Original Article

October 7, 2018


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