Neurospine

Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.

The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Review Article

March 31, 2022

Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations

J.C. Le Huec, S. AlEissa, A.J. Bowey, B. Debono, A. El-Shawarbi, N. Fernández-Baillo, K.S. Han, A. Martin-Benlloch, R. Pflugmacher, P. Sabatier, et al.

Neurospine. 2022;19(1):1-12.

Bleeding in spine surgery is a common occurrence but when bleeding is uncontrolled the consequences can be severe due to the potential for spinal cord compression and damage to the...

Review Article

February 2, 2022

Glioma Immunotherapy: Advances and Challenges for Spinal Cord Gliomas

Clare Grady, Kaitlyn Melnick, Ken Porche, Farhad Dastmalchi, Daniel J. Hoh, Maryam Rahman, Ashley Ghiaseddin

Neurospine. 2022;19(1):13-29.

Spinal cord gliomas are rare entities that often have limited surgical options. Immunotherapy has shown promise in intracranial gliomas with some research suggesting benefit for spinal cord gliomas. A focused...

Original Article

January 30, 2022

Remnant Tumor Margin as Predictive Factor for Its Growth After Incomplete Resection of Cervical Dumbbell-Shaped Schwannomas

Kazuya Kitamura, Narihito Nagoshi, Osahiko Tsuji, Satoshi Suzuki, Satoshi Nori, Eijiro Okada, Mitsuru Yagi, Morio Matsumoto, Masaya Nakamura, Kota Watanabe

Neurospine. 2022;19(1):32-40.

Objective: The purpose of our study was to investigate the risk factors of remnant tumor growth after incomplete resection (IR) of cervical dumbbell-shaped schwannomas (DS). Methods: Twenty-one patients with IR of...

Original Article

January 30, 2022

Steroids in the Management of Preoperative Neurological Deficits in Metastatic Spine Disease: Results From the EPOSO Study

Anne L. Versteeg, Lior M. Elkaim, Arjun Sahgal, Laurence D. Rhines, Daniel M. Sciubba, James M. Schuster, Michael G. Fehlings, Aron Lazary, Michelle J. Clarke, Paul M. Arnold, et al.

Neurospine. 2022;19(1):43-50.

Objective: Patients presenting with neurological deficit secondary to metastatic epidural spinal cord compression (MESCC) are often treated with surgery in combination with high-dose corticosteroids. Despite steroids being commonly used, the...

Original Article

February 2, 2022

Frailty Status Is a More Robust Predictor Than Age of Spinal Tumor Surgery Outcomes: A NSQIP Analysis of 4,662 Patients

Syed Faraz Kazim, Alis J. Dicpinigaitis, Christian A. Bowers, Smit Shah, William T. Couldwell, Rachel Thommen, Daniel J. Alvarez-Crespo, Matthew Conlon, Omar H. Tarawneh, John Vellek, et al.

Neurospine. 2022;19(1):53-62.

Objective: The present study aimed to evaluate the effect of baseline frailty status (as measured by modified frailty index-5 [mFI-5]) versus age on postoperative outcomes of patients undergoing surgery for...

Original Article

February 3, 2022

Clinical Features, Treatments, and Prognosis of Intramedullary Spinal Cord Metastases From Lung Cancer: A Case Series and Systematic Review

Liang Wu, Li'ao Wang, Jun Yang, Wenqing Jia, Yulun Xu

Neurospine. 2022;19(1):65-76.

Objective: Intramedullary spinal cord metastasis from lung cancer (ISCM-LC) are increasing in prevalence. We aim to investigate its clinical features, treatments and prognosis. Methods: We reported 6 ISCM-LC cases and conducted...

Original Article

January 17, 2022

Recovery Potential of Spinal Meningioma Patients With Preoperative Loss of Walking Ability Following Surgery – A Retrospective Single-Center Study

Ville Vasankari, Roel Haeren, Mika Niemelä, Miikka Korja

Neurospine. 2022;19(1):77-83.

Objective: Spinal meningiomas are neurosurgical rarities that manifest with progressive paraor tetraparesis. The effect of timing of surgery on the recovery after the loss of walking ability is poorly known....

Original Article

March 31, 2022

Hardware Failure in Spinal Tumor Surgery: A Hallmark of Longer Survival?

Nikita Zaborovskii, Adam Schlauch, Dmitrii Ptashnikov, Dmitrii Mikaylov, Sergei Masevnin, Oleg Smekalenkov, John Shapton, Dimitriy Kondrashov

Neurospine. 2022;19(1):84-95.

Objective: Instrumentation failure in spine tumor surgery is a common reason for revision operation. Increases in patient survival demand a better understanding of the hardware longevity. The study objective was...

Original Article

March 31, 2022

Functional Outcome After Spinal Meningioma Surgery. A Nationwide Population-Based Study

Charles Champeaux-Depond, Nicolas Penet, Joconde Weller, Jean-Charles Le Huec, Vincent Jecko

Neurospine. 2022;19(1):96-107.

Objective: To describe and analysed the functional outcome (FO) after spinal meningioma (SM) surgery. Methods: We processed the système national des données de santé (SNDS) i.e. , the French national administrative...

Original Article

March 31, 2022

Intramedullary Spinal Cord Lesions: A Single-Center Experience

Vincent Jecko, Paul Roblot, Lorenzo Mongardi, Morgan Ollivier, Natalia Delgado Piccoli, Thomas Charleux, Thomas Wavasseur, Edouard Gimbert, Dominique Liguoro, Guillaume Chotard, et al.

Neurospine. 2022;19(1):108-117.

Objective: Spinal cord tumors constitute a small part of spinal surgery owing to their rarity. This retrospective study describes their current management. Methods: Forty-eight patients were treated for an intramedullary tumor...

Original Article

March 31, 2022

Long-term Neurologic Outcome After Spinal Ependymoma Resection With Multimodal Intraoperative Electrophysiological Recording: Cohort Study and Review of the Literature

Grégoire P. Chatain, Michael W. Kortz, Stephanie Serva, Keshari Shrestha, Patrick Hosokawa, Timothy H. Ung, Michael Finn

Neurospine. 2022;19(1):118-132.

Objective: To evaluate how multimodal intraoperative neuromonitoring (IONM) changes during spinal ependymoma (SE) resection correlate with long-term neuro-functional outcomes. Methods: A retrospective analysis of patients aged 18 years or older who...

Original Article

March 31, 2022

Prediction of Discharge Status and Readmissions after Resection of Intradural Spinal Tumors

Michael C. Jin, Allen L. Ho, Austin Y. Feng, Zachary A. Medress, Arjun V. Pendharkar, Paymon Rezaii, John K. Ratliff, Atman M. Desai

Neurospine. 2022;19(1):133-145.

Objective: Intradural spinal tumors are uncommon and while associations between clinical characteristics and surgical outcomes have been explored, there remains a paucity of literature unifying diverse predictors into an integrated...

Original Article

March 31, 2022

Mechanical Failure After Total En Bloc Spondylectomy and Salvage Surgery

Shin Won Kwon, Chun Kee Chung, Young Il Won, Woon Tak Yuh, Sung Bae Park, Seung Heon Yang, Chang Hyun Lee, John M. Rhee, Kyoung-Tae Kim, Chi Heon Kim

Neurospine. 2022;19(1):146-154.

Objective: Total en bloc spondylectomy (TES) is a curative surgical method for spinal tumors. After resecting the 3 spinal columns, reconstruction is of paramount importance. We present cases of mechanical...

Review Article

March 31, 2022

Pearls and Pitfalls of Oblique Lateral Interbody Fusion: A Comprehensive Narrative Review

Hyoungmin Kim, Bong-Soon Chang, Sam Yeol Chang

Neurospine. 2022;19(1):163-176.

Lumbar degenerative disease is a common problem in an aging society. Oblique lateral interbody fusion (OLIF) is a minimally invasive surgical (MIS) technique that utilizes a retroperitoneal antepsoas corridor to...

Review Article

January 29, 2022

Clinical Issues in Indication, Correction, and Outcomes of the Surgery for Neuromuscular Scoliosis: Narrative Review in Pedicle Screw Era

Hak Sun Kim, Ji Won Kwon, Kun-Bo Park

Neurospine. 2022;19(1):177-187.

Surgical treatment for neuromuscular scoliosis has evolved with pedicle screw instrumentation and the improvement of perioperative management. We aimed to review recent papers related to posterior surgical correction with a...

Original Article

January 2, 2022

Location Distribution of Fistulas and Surgical Strategies for Spinal Extradural Meningeal Cysts: A Retrospective Analysis of 30 Cases at a Single Center

Qiang Jian, Gang Song, Zhenlei Liu, Wanru Duan, Jian Guan, Fengzeng Jian, Zan Chen

Neurospine. 2022;19(1):188-201.

Objective: This study aimed to illustrate the features of fistula location distribution, surgical strategies, and outcomes in spinal epidural meningeal cysts (SEMCs). Methods: The authors searched and reviewed the medical records...

Original Article

February 2, 2022

Reconstruction of the Cervical Lateral Mass Using 3-Dimensional-Printed Prostheses

Qiang Jian, Zhenlei Liu, Wanru Duan, Jian Guan, Fengzeng Jian, Zan Chen

Neurospine. 2022;19(1):202-211.

Objective: This study aimed to investigate the outcome of using 3-dimensional (3D)-printed prostheses to reconstruct a cervical lateral mass to maintain cervical stability. Methods: We retrospectively analyzed data of 7 patients...

Original Article

February 2, 2022

Comparative Analysis of 3 Types of Minimally Invasive Posterior Cervical Foraminotomy for Foraminal Stenosis, Uniportal-, Biportal Endoscopy, and Microsurgery: Radiologic and Midterm Clinical Outcomes

Ji Yeon Kim, Hyun Jin Hong, Dong Chan Lee, Tae Hyun Kim, Jin Seob Hwang, Choon Keun Park

Neurospine. 2022;19(1):212-223.

Objective: The aim of this study was to compare the clinical and radiologic outcomes of 3 types of minimally invasive posterior cervical foraminotomy (PCF): uniportal endoscopic surgery, biportal endoscopic surgery,...

Original Article

March 31, 2022

Risk Factors for Poor Outcomes Following Minimally Invasive Discectomy: A Post Hoc Subgroup Analysis of 2-Year Follow-up Prospective Data

Zihao Chen, Lei He, Lijun Huang, Zhongyu Liu, Jianwen Dong, Bin Liu, Ruiqiang Chen, Liangming Zhang, Peigen Xie, Limin Rong

Neurospine. 2022;19(1):224-235.

Objective: A post hoc subgroup analysis of prospectively collected data from a randomized controlled trial was conducted to identify risk factors related to poor outcomes in patients who underwent minimally...

Original Article

March 31, 2022

The Last Touched Vertebra on Supine Radiographs Can Be the Optimal Lower Instrumented Vertebra in Adolescent Idiopathic Scoliosis Patients

Do-Hyoung Kim, Seung-Jae Hyun, Chang-Hyun Lee, Ki-Jeong Kim

Neurospine. 2022;19(1):236-243.

Objective: To determine whether the last touched vertebra (LTV) on supine radiographs is suitable for the lower instrumented vertebra (LIV) in adolescent idiopathic scoliosis (AIS) correction surgery. Methods: In total, 57...

Original Surgical Treatment and Long-term Follow-up for Chronic Inflammatory Demyelinating Polyradiculoneuropathy Causing A Compressive Cervical Myelopathy Julien Rigal, Emanuele Quarto, Lisa Boue, Laurent Balabaud, Wendy Thompson, Thibault Cloché, Stephane Bourret, Jean Charles Le Huec [Accepted] Original article(Clinical) May 17, 2022 PDF	Difference in the Cobbs Angle Between Standing and Supine Position as a Prognostic Factor After Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures In-Suk Bae, Byung Gwan Moon, Hee In Kang, Jae Hoon Kim, Cheolsu Jwa, Deok Ryeong Kim [Accepted] Original article(Clinical) May 17, 2022 PDF
Recent Molecular and Genetic Findings in Intramedullary Spinal Cord Tumors Yoshitaka Nagashima, Yusuke Nishimura, Kaoru Eguchi, Junya Yamaguchi, Shoichi Haimoto, Fumiharu Ohka, Masakazu Takayasu, Ryuta Saito [Accepted] Review Article May 16, 2022 PDF	Comparison of the Clinical Efficacy of Transforaminal Endoscopy and Microtubular Technology for the Treatment of Lumbar Dumbbell-Shaped Tumors Rui Wang, Ze Yan Liang, Yan Chen, Chun Mei Chen [Accepted] Special issue (Minimally Invasive Spine Surgery) May 16, 2022 PDF
Impact of Radiation Therapy on Outcomes After Spinal Instrumentation for Craniocervical Junction Malignancies Matthew Muir, Laurence Rhines, Franco Demonte, Claudio Tatsui, Shaan M. Raza [Accepted] Original article(Clinical) May 15, 2022 PDF	Psychometric Properties of the Scoliosis Research Society Questionnaire (Version 22r) Domains Among Adults With Spinal Deformity: A Rasch Measurement Theory Analysis Kati Kyrölä, Susanna Hiltunen, Mikko M. Uimonen, Jari Ylinen, Arja Häkkinen, Jussi P. Repo [Accepted] Original article(Clinical) May 15, 2022 PDF
Analysis of Associating Radiologic Parameters With Clinical Outcomes after Posterior C1–2 Fusion Jong-Hyeok Park, Jong Tae Kim, Il Sup Kim, Jae Taek Hong [Accepted] Original article(Clinical) May 15, 2022 PDF	The Change of Spinal Canal According to Oblique Lumbar Interbody Fusion in Degenerative Spondylolisthesis: A Prospective Observational Study Young-Seok Lee, Dong-Hyun Lee, Dae-Chul Cho, In-bo Han, Chi Heon Kim, Heum-Dai Kwon, Kyoung-Tae Kim [Accepted] Special issue (Minimally Invasive Spine Surgery) May 13, 2022 PDF
What Type of Incision for Anterior Cervical Spine Surgery Involving Long Segments Can Bring Better Cosmetic and Functional Outcomes? Hyung Rae Lee, Dong-Ho Lee, Sang Yun Seok, Se han Park, Jae Hwan Cho, Chang Ju Hwang, Choon Sung Lee [Accepted] Original article(Clinical) May 13, 2022 PDF	Prevalence and Clinical Impact of Cervical Facet Joint Degeneration on Degenerative Cervical Myelopathy: a Novel Computed Tomography Classification Study Ai Okamoto, Yasuhiro Takeshima, Shohei Yokoyama, Fumihiko Nishimura, Ichiro Nakagawa, Young-Soo Park, Hiroyuki Nakase [Accepted] Original article(Clinical) May 13, 2022 PDF
Biomechanical Analysis of 3-Level Anterior Cervical Discectomy and Fusion Under Physiologic Loads Using a Finite Element Model Lee A Tan, Narayan Yoganandan, Hoon Choi, Yuvaraj Purushothaman, Davidson Jebaseelan, Aju Bosco [Accepted] Original article(Basic) May 13, 2022 PDF	Learning Curve of ROSA ONE Spine System for Transpedicular Screw Placement Bing-Hung Hsu, Heng-Wei Liu, Kha-Liang Lee, Ming-Chin Lin, Gao Chen, Jang Yu, Chiao-Ling Chen, I-Chang Su Su, Chien-Min Lin [Accepted] Original article(Clinical) May 12, 2022 PDF
Conversational Artificial Intelligence for Spinal Pain Questionnaire: Validation and User Satisfaction Kyoung Hyup Nam, Da Young Kim, Dong Hwan Kim, Jung Hwan Lee, Jae Il Lee, Mi Jeong Kim, Joo Young Park, Jae Hyun Hwang, Sang Seok Yun, Byung Kwan Choi, et al. [Accepted] Original article(Clinical) May 12, 2022 PDF	Cost-Utility Analysis Compared Between Radiotherapy Alone and Combined Surgery and Radiotherapy for Symptomatic Spinal Metastases in Thailand Pasawat Taechalertpaisarn, Sirichai Wilartratsami, Pochamana Phisalprapa, Chayanis Kositamongkol, Achiraya Teyateeti, Panya Luksanapruksa [Accepted] Original article(Clinical) May 12, 2022 PDF
Analysis of the Incidence and Risk Factors of Postoperative Delirium in Patients With Degenerative Cervical Myelopathy Namhoo Kim, Tae-Hwan Kim, Jae Keun Oh, Jeongsup Lim, Kang Uk Lee, Seok Woo Kim [Accepted] Original article(Clinical) May 12, 2022 PDF	Effects of Anterior Plating on Achieving Clinically Meaningful Improvement Following Single-Level Anterior Cervical Discectomy and Fusion Conor P. Lynch, Elliot D.K. Cha, Madhav R. Patel, Caroline N. Jadczak, Shruthi Mohan, Cara E. Geoghegan, Kern Singh [Accepted] Original article(Clinical) January 2, 2022 PDF
Higher American Society of Anesthesiologists Classification Does Not Limit Safety or Improvement Following Minimally Invasive Transforaminal Lumbar Interbody Fusion Conor P. Lynch, Elliot D.K. Cha, Cara E. Geoghegan, Caroline N. Jadczak, Shruthi Mohan, Kern Singh [Accepted] Original article(Clinical) January 2, 2022 PDF	What Can Legacy Patient-Reported Outcome Measures Tell Us About Participation Bias in Patient-Reported Outcomes Measurement Information System Scores Among Lumbar Spine Patients? Conor P. Lynch, Elliot D.K. Cha, Caroline N Jadczak, Shruthi Mohan, Cara E. Geoghegan, Kern Singh [Accepted] Original article(Clinical) January 2, 2022 PDF