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Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.
The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Review Article

March 31, 2020


Gene Therapy Approach for Intervertebral Disc Degeneration: An Update
Yoshiki Takeoka, Takashi Yurube, Kotaro Nishida
Neurospine. 2020;17(1):3-14.

Review Article

March 31, 2020


Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Review
Tibo Nico Emmie Volleman, Jordy Schol, Kosuke Morita, Daisuke Sakai, Masahiko Watanabe
Neurospine. 2020;17(1):19-35.

Original Article

March 31, 2020


Correlation of Early Outcomes and Intradiscal Interleukin-6 Expression in Lumbar Fusion Patients
John D. Koerner, Dessislava Z. Markova, Greg D. Schroeder, Christopher L. Antonacci, Joseph Mendelis, Alexander R. Vaccaro, D. Greg Anderson, Chris K. Kepler
Neurospine. 2020;17(1):36-41.

Original Article

March 31, 2020


Direct and Intervertebral DiscMediated Sensitization of Dorsal Root Ganglion Neurons by Hypoxia and Low pH
Junxuan Ma, Despina Stefanoska, Sibylle Grad, Mauro Alini, Marianna Peroglio
Neurospine. 2020;17(1):42-59.

Original Article

March 31, 2020


Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells
Nam Vo, Brandon Couch, Joon Lee, Gwendolyn Sowa, James Kang, Studer Rebecca
Neurospine. 2020;17(1):60-68.

Original Article

March 31, 2020


Rabbit Annulus Fibrosus Cells Express Neuropeptide Y, Which Is Influenced by Mechanical and Inflammatory Stress
Malcolm E. Dombrowski, Adam S. Olsen, Nicholas Vaudreuil, Brandon K. Couch, Qing Dong, Michelle Tucci, Joon Y. Lee, Nam V. Vo, Gwendolyn Sowa
Neurospine. 2020;17(1):69-76.

Original Article

March 31, 2020


Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype
Rahel D. May, Daniela A. Frauchiger, Christoph E. Albers, Willy Hofstetter, Benjamin Gantenbein
Neurospine. 2020;17(1):77-87.

Review Article

March 31, 2020


Robotic Spine Surgery and Augmented Reality Systems: A State of the Art
Gianluca Vadalà, Sergio De Salvatore, Luca Ambrosio, Fabrizio Russo, Rocco Papalia, Vincenzo Denaro
Neurospine. 2020;17(1):88-100.

Review Article

November 4, 2019


Biomaterials in Spinal Implants: A Review
Andrew Warburton, Steven J. Girdler, Christopher M. Mikhail, Amy Ahn, Samuel K. Cho
Neurospine. 2020;17(1):101-110.

Original Article

March 31, 2020


Telerobotic Spinal Surgery Based on 5G Network: The First 12 Cases
Wei Tian, Mingxing Fan, Cheng Zeng, Yajun Liu, Da He, Qi Zhang
Neurospine. 2020;17(1):114-120.

Original Article

March 31, 2020


Polyetheretherketone Versus Titanium Cages for Posterior Lumbar Interbody Fusion: Meta-Analysis and Review of the Literature
Elie Massaad, Nida Fatima, Ali Kiapour, Muhamed Hadzipasic, Ganesh M. Shankar, John H. Shin
Neurospine. 2020;17(1):125-135.

Original Article

April 12, 2019


Rigid-Plating and Cortico-Cancellous Allograft Are Effective for 3-Level Anterior Cervical Discectomy and Fusion: Radiographic and Clinical Outcomes
Philip K. Louie, Andrew C. Sexton, Danel D. Bohl, Ehsan Tabaraee, Steven M. Presciutti, Benjamin C. Mayo, Justin C. Paul, Comron Saifi, Howard S. An
Neurospine. 2020;17(1):146-155.

Original Article

July 5, 2019


Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
Chi Hyung Lee, Dong Wuk Son, Su Hun Lee, Jun Seok Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
Neurospine. 2020;17(1):156-163.

Original Article

July 9, 2019


Degenerative Cervical Myelopathy: A 7-Letter Coding System That Supports Decision-Making for the Surgical Approach
Luca Papavero, Gregor Schmeiser, Ralph Kothe, Bronek Boszczyk, Oliver Heese, Yoshiharu Kawaguchi, Anna MacDowall, Claes Olerud, Nikolaos Paidakakos, Anastasios Panagiotou, et al.
Neurospine. 2020;17(1):164-171.

Original Article

March 31, 2020


Effect of the Presence and Type of Plate Augmentation on Postoperative Dysphagia Among Adult Patients Undergoing Elective Anterior Cervical Discectomy and Fusion for Spondylosis: A Randomized Trial
Tom J. O’Donohoe, Lisa Mililli, Alison Magee, Christopher Thien, Yi Yuen Wang
Neurospine. 2020;17(1):174-183.

Original Article

February 5, 2020


Evaluation of Postoperative Mental Health Outcomes in Patients Based on Patient-Reported Outcome Measurement Information System Physical Function Following Anterior Cervical Discectomy and Fusion
Joon S. Yoo, Nathaniel W. Jenkins, James M. Parrish, Thomas S. Brundage, Nadia M. Hrynewycz, Franchesca A. Mogilevsky, Kern Singh
Neurospine. 2020;17(1):184-189.

Original Article

March 31, 2020


The Impact of Modic Changes on Preoperative Symptoms and Clinical Outcomes in Anterior Cervical Discectomy and Fusion Patients
James D. Baker, Garrett K. Harada, Youping Tao, Philip K. Louie, Bryce A. Basques, Fabio Galbusera, Frank Niemeyer, Hans-Joachim Wilke, Howard S. An, Dino Samartzis
Neurospine. 2020;17(1):190-203.

Original Article

March 31, 2020


Timing of Surgery in Tubular Microdiscectomy for Lumbar Disc Herniation and Its Effect on Functional Impairment Outcomes
Alessandro Siccoli, Marlies P. de Wispelaere, Marc L. Schröder, Victor E. Staartjes
Neurospine. 2020;17(1):204-212.

Original Article

March 31, 2020


The Influence of Mechanic Factors in Disc Degeneration Disease as a Determinant for Surgical Indication
Gulden Demirci Otluoğlu, Deniz Konya, Zafer Orkun Toktas
Neurospine. 2020;17(1):215-220.

Original Article

March 31, 2020


Image-Based Markers Predict Dynamic Instability in Lumbar Degenerative Spondylolisthesis
William Slikker III, Alejandro A. Espinoza Orías, Grant D. Shifflett, Joe Y.B. Lee, Krzysztof Siemionow, Sapan Gandhi, Louis Fogg, Dino Samartzis, Nozomu Inoue, Howard S. An
Neurospine. 2020;17(1):221-227.

Original Article

March 31, 2020


Less Opioid Consumption With Enhanced Recovery After Surgery Transforaminal Lumbar Interbody Fusion (TLIF): A Comparison to Standard Minimally-Invasive TLIF
Hsuan-Kan Chang, Meng Huang, Jau-Ching Wu, Wen-Cheng Huang, Michael Y. Wang
Neurospine. 2020;17(1):228-236.

Original Article

July 24, 2019


Use of Opioids and Other Analgesics Before and After Primary Surgery for Adult Spinal Deformity: A 10-Year Nationwide Study
Frederik Taylor Pitter, Matt Sikora, Martin Lindberg-Larsen, Alma Becic Pedersen, Benny Dahl, Martin Gehrchen
Neurospine. 2020;17(1):237-245.

Original Article

March 31, 2020


Opioids and Spinal Cord Stimulators: Pre- and Postoperative Opioid Use Patterns and Predictors of Prolonged Postoperative Opioid Use
Lawal Labaran, Jomar N.A. Aryee, Joshua Bell, Nikhil Jain, Varun Puvanesarajah, Michael Raad, Amit Jain, Jonathan Carmouche, Hamid Hassanzadeh
Neurospine. 2020;17(1):246-253.

Original Article

February 1, 2020


Comparison of the Safety and Effectiveness of Percutaneous Endoscopic Lumbar Discectomy for Treating Lumbar Disc Herniation Under Epidural Anesthesia and General Anesthesia
Zhiqiang Ren, Shenghua He, Jiao Li, Yeguang Wang, Juyi Lai, Zhitao Sun, Hualong Feng, Jian Wang
Neurospine. 2020;17(1):254-259.

Original Article

February 5, 2020


The Navigated Oblique Lumbar Interbody Fusion: Accuracy Rate, Effect on Surgical Time, and Complications
Zhuo Xi, Dean Chou, Praveen V. Mummaneni, Shane Burch
Neurospine. 2020;17(1):260-267.

Original Article

January 26, 2020


Lower Extremity Motor Deficits Are Underappreciated in Patient-Reported Outcome Measures: Added Value of Objective Outcome Measures
Martin Nikolaus Stienen, Nicolai Maldaner, Marketa Sosnova, Holger Joswig, Marco Vincenzo Corniola, Luca Regli, Gerhard Hildebrandt, Karl Schaller, Oliver Pascal Gautschi
Neurospine. 2020;17(1):270-280.

Original Article

October 15, 2019


A New Shielding Curtain for Protection of Intraoperative Radiation During Minimally Invasive Spine Surgery
Se Hoon Park, Myeong Jin Ko, Yong Sook Park, Jaehan Yun, Hongsik Byun, Seung Won Park
Neurospine. 2020;17(1):288-293.

Original Article

July 11, 2019


Re-examining the Spectrum of Lumbosacral Transitional Dysmorphisms: Quantifying Joint Asymmetries and Evaluating the Anatomy of Screw Fixation Corridors
Niladri Kumar Mahato
Neurospine. 2020;17(1):294-303.

Original Article

February 1, 2020


Oxford Cobbometer Versus Computer Assisted-Software for Measurement of Cobb Angle in Adolescent Idiopathic Scoliosis
Tarek Elfiky, Nirmal Patil, Mohamed Shawky, Ahmed Siam, Raafat Ragab, Yasser Allam
Neurospine. 2020;17(1):304-311.

The Relationship Between Preoperative Patient-Reported Outcomes Measurement Information System Scores With Postoperative Improvements in Physical Function After Anterior Cervical Discectomy and Fusion
James M. Parrish, Nathaniel W. Jenkins, Nadia M. Hrynewycz, Thomas S. Brundage, Kern Singh
[Accepted]

Original article(Clinical)

February 5, 2020

Perioperative Anesthesia Lean Implementation is Associated With Increased Operative Efficiency in Posterior Cervical Surgeries at a High-Volume Spine Center
Simon Gashaw Ammanuel, Andrew Kai-Hong Chan, Anthony M DiGiorgio, Mohanad Alazzeh, Kelechi Nwachuku, Leslie C. Robinson, Errol Lobo, Praveen V. Mummaneni
[Accepted]

Original article(Clinical)

February 5, 2020

Analysis and Temporal Evolution of Extubation Parameters for Patients Undergoing Single Stage Circumferential Cervical Spine Surgery
Ricardo B.V. Fontes, Mena G. Kerolus, Ryan B. Kochanski, Rajeev K. Garg, Anthony DelaCruz, Vincent C. Traynelis
[Accepted]

Original article(Clinical)

February 2, 2020

Novel Technique for C1–2 Interlaminar Arthrodesis Utilizing a Modified Sonntag Loop-Suture Graft With Posterior C1–2 Fixation
Robert Mawunyo Koffie, Alexandra Giantini Larsen, Benjamin L. Grannan, Muhamed Hadzipasic, Vijay Yanamadala, Ganesh M. Shankar, Laura Van Beaver, John H. Shin
[Accepted]

Technical note

February 2, 2020

Demographic Trends in Paddle Lead Spinal Cord Stimulator Placement: Private Insurance and Medicare Beneficiaries
Lawal Labaran, Joshua Bell, Varun Puvanesarajah, Nikhil Jain, Jomar N. Aryee, Micheal Raad, Amit Jain, Jonathan Carmouche, Hamid Hassanzadeh
[Accepted]

Original article(Clinical)

February 1, 2020

Dual S2 Alar-Iliac Screw Technique With a Multirod Construct Across the Lumbosacral Junction: Obtaining Adequate Stability at the Lumbosacral Junction in Spinal Deformity Surgery
Paul J. Park, James D. Lin, Melvin C. Makhni, Meghan Cerpa, Ronald A. Lehman, Lawrence G. Lenke
[Accepted]

Case report

November 4, 2019

A Sufficient Surgical Window for Deep-Seated Extracranial Schwannomas in the Craniocervical Junction by the Anterolateral Approach
Yu-ichiro Ohnishi, Nobuhiko Nakajima, Sho Fujiwara, Takashi Moriwaki, Hideyuki Arita, Haruhiko Kishima
[Accepted]

Technical note

November 4, 2019

Neurologic Deficit during Halo-Gravity Traction in the Treatment of Severe Thoracic Kyphoscoliotic Spinal Deformity
Martin H. Pham, Meghan Cerpa, Melvin C. Makhni, John Alexander Sielatycki, Lawrence G. Lenke
[Accepted]

Case report

August 25, 2019

Bicortical Screw Purchase at Upper Instrumented Vertebra (UIV) Can Cause UIV Fracture After Adult Spinal Deformity Surgery: A Finite Element Analysis Study
Seong-Hyun Wui, Seung-Jae Hyun, Bokku Kang, Ki-Jeong Kim, Tae-Ahn Jahng, Hyun Jib Kim
[Accepted]

Original article(Basic)

July 11, 2019

Robot-Assisted Microendoscopic Discectomy for Lumbar Disc Herniation: Operative Technique
Sultan Alsalmi, Abdulgadir Bugdadi, Abdu Alkhyari, Johann Peltier, Michel Lefranc
[Accepted]

Original article(Clinical)

July 9, 2019


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