Neurospine

Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.

The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Essay

December 31, 2020

History of Spinal Neurosurgery and Spine Societies

Mehmet Zileli, Salman Sharif, Maurizio Fornari, Premenand Ramani, Fengzeng Jian, Richard Fessler, Se-Hoon Kim, Toshihiro Takami, Nobuyuki Shimokawa, Gilbert Dechambenoit, et al.

Neurospine. 2020;17(4):675-694.

Essay

December 31, 2020

The Art of Diagnosis in the Cervical Spine

Melvin C. Makhni, Caleb M. Yeung, K. Daniel Riew

Neurospine. 2020;17(4):695-703.

Review Article

December 31, 2020

Early Management of Cervical Spine Trauma: WFNS Spine Committee Recommendations

Mehmet Zileli, Enrique Osorio-Fonseca, Nikolay Konovalov, Carlos Cardenas-Jalabe, Stanislav Kaprovoy, Sergey Mlyavykh, Artur Pogosyan

Neurospine. 2020;17(4):710-722.

Epidemiology, prevention, early management of cervical spine trauma and it's reduction are the objectives of this review paper. A PubMed and MEDLINE search between 2009 and 2019 were conducted using...

Review Article

December 31, 2020

Upper Cervical Spine Trauma: WFNS Spine Committee Recommendations

Oscar L. Alves, Leopoldina Pereira, Se-Hoon Kim, Andrey Grin, Nobuyuki Shimokawa, Nikolay Konovalov, Mehmet Zileli

Neurospine. 2020;17(4):723-736.

Craniovertebral junction (CVJ) trauma is a challenging clinical condition. Being a highly mobile functional unit at the junction of the skull and the vertebral column, traumatic events in this area...

Review Article

December 31, 2020

Subaxial Cervical Spine Injuries: WFNS Spine Committee Recommendations

Salman Sharif, Muhammad Yassar Jazaib Ali, Ibet Marie Y. Sih, Jutty Parthiban, Óscar L. Alves

Neurospine. 2020;17(4):737-758.

To formulate specific guidelines for the recommendation of subaxial cervical spine injuries concerning classification, management, posttraumatic locked facets and vertebral artery injury. Computerized literature was searched on PubMed and google...

Review Article

December 31, 2020

Early Management of Spinal Cord Injury: WFNS Spine Committee Recommendations

José Antonio Soriano Sánchez, Salman Sharif, Francesco Costa, Jose Alberto Israel Romero Rangel, Carla Daniela Anania, Mehmet Zileli

Neurospine. 2020;17(4):759-784.

Scientific knowledge today is being generated more rapidly than we can assimilate thus requiring continuous review of gold-standards for diagnosis and treatment of specific pathologies. The aim of this paper...

Review Article

December 31, 2020

Pharmacologic and Regenerative Cell Therapy for Spinal Cord Injury: WFNS Spine Committee Recommendations

Toshihiro Takami, Nobuyuki Shimokawa, Jutty Parthiban, Mehmet Zileli, Sheena Ali

Neurospine. 2020;17(4):785-796.

This is a review article examining the pharmacologic and regenerative cell therapy for spinal cord injury. A literature search during last 10 years were conducted using key words. Case reports,...

Review Article

December 31, 2020

Pediatric Cervical Spine Injuries and SCIWORA: WFNS Spine Committee Recommendations

Nikolay Konovalov, Nikolay Peev, Mehmet Zileli, Salman Sharif, Stanislav Kaprovoy, Stanislav Timonin

Neurospine. 2020;17(4):797-808.

Cervical trauma in children have variations from the adults mainly due to anatomic differences. An optimal diagnostic and treatment strategy is critical, particularly when there is a lack of standardized...

Review Article

December 31, 2020

Outcomes of Spinal Cord Injury: WFNS Spine Committee Recommendations

Jutty Parthiban, Mehmet Zileli, Salman Yousuf Sharif

Neurospine. 2020;17(4):809-819.

This comprehensive review article aims to provide some definitive statements on the factors like clinical syndromes, radiological findings, and decompressive surgery, that may influence the outcomes in cervical spinal cord...

Review Article

December 31, 2020

Rehabilitation of Spinal Cord Injury: WFNS Spine Committee Recommendations

Nikolay Peev, Alexander Komarov, Enrique Osorio-Fonseca, Mehmet Zileli

Neurospine. 2020;17(4):820-832.

Spinal cord injury (SCI) is accompanied by a significant number of complications associated with damage to the spinal cord, gross functional impairments leading to limited self-care and movement, leading to...

Review Article

December 31, 2020

Cervical Deformity: Evaluation, Classification, and Surgical Planning

Ahilan Sivaganesan, Justin S. Smith, Han Jo Kim

Neurospine. 2020;17(4):833-842.

Cervical deformity is a challenging condition to treat and requires complex decision-making. Apart from a thorough history and physical examination, a thoughtful and quantitative analysis of multiple imaging modalities is...

Original Article

December 31, 2020

Weak Ligaments and Sloping Joints: A New Hypothesis for Development of Congenital Atlantoaxial Dislocation and Basilar Invagination

Avnish K. Chauhan, P. Sarat Chandra, Nishant Goyal, Madhumita R. Chowdhury, Jyotirmoy Banerjee, Manjari Tripathi, Madhulika Kabra

Neurospine. 2020;17(4):843-856.

Objective: Developmental bony craniovertebral junction (CVJ) anomalies seem to have a genetic basis and also abnormal joint morphology causing atlantoaxial dislocation (AAD) and basilar invagination (BI). Methods: DNA extracted polymerase chain...

Original Article

December 31, 2020

Longitudinal Evaluation of Patient-Reported Outcomes Measurement Information System for Back and Leg Pain in Minimally Invasive Transforaminal Lumbar Interbody Fusion

Nathaniel W. Jenkins, James M. Parrish, Nadia M. Hrynewycz, Thomas S. Brundage, Kern Singh

Neurospine. 2020;17(4):862-870.

Objective: While visual analogue score (VAS) metrics are among the most universally adopted patient-reported outcome measures (PROMs), there is limited research on the influence of back and leg pain on...

Original Article

December 31, 2020

Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis

Anoop R. Galivanche, Raj Gala, Preetpaul S. Bagi, Arianne J. Boylan, Christopher M. Dussik, Pedro D. Coutinho, Jonathan N. Grauer, Arya G. Varthi

Neurospine. 2020;17(4):871-878.

Objective: To compare the perioperative morbidity of 2-level anterior cervical discectomy and fusion (ACDF) with that of 1-level anterior cervical corpectomy and fusion (ACCF) for the treatment of cervical degenerative...

Original Article

December 31, 2020

Chronic Opioid Use Following Lumbar Discectomy: Prevalence, Risk Factors, and Current Trends in the United States

Andrew B. Harris, Bo Zhang, Majd Marrache, Varun Puvanesarajah, Micheal Raad, Hamid Hassanzadeh, Mark Bicket, Amit Jain

Neurospine. 2020;17(4):879-887.

Objective: Lumbar discectomy is commonly performed for symptomatic lumbar disc herniation. We aimed to examine prescribing patterns and risk factors for chronic opioid use following lumbar discectomy. Methods: Using a private...

Original Article

December 31, 2020

Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis

Lauren K. Dunn, Ching-Jen Chen, Davis G. Taylor, Kamilla Esfahani, Brian Brenner, Charles Luo, Thomas J. Buell, Sarah N. Spangler, Avery L. Buchholz, Justin S. Smith, et al.

Neurospine. 2020;17(4):888-895.

Objective: This was a retrospective, cohort study investigating the efficacy and safety of continuous low-dose postoperative tranexamic acid (PTXA) on drain output and transfusion requirements following adult spinal deformity surgery. Methods:...

Original Article

December 31, 2020

Synthetic Cages Associated With Increased Rates of Revision Surgery and Higher Costs Compared to Allograft in ACDF in the Nonelderly Patient

Majd Marrache, Rachel Bronheim, Andrew B. Harris, Varun Puvanesarajah, Micheal Raad, Sang Lee, Richard Skolasky, Amit Jain

Neurospine. 2020;17(4):896-901.

Objective: The aim of this study was to compare all-cause reoperation rates and costs in nonelderly patients treated with anterior cervical discectomy and fusion (ACDF) with structural allograft versus synthetic...

Original Article

December 31, 2020

Selection of the Lowest Instrumented Vertebra and Relative Odds Ratio of Distal Adding-on for Lenke Type 1A and 2A Curves in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis

Che-Wei Liu, Lawrence G. Lenke, Lee A. Tan, Taemin Oh, Kou-Hua Chao, Shi-Ding Lin, Ru-Yu Pan

Neurospine. 2020;17(4):902-909.

Objective: To examine existing literature and pool the data to determine the relative odds ratio of “adding-on” (AO) based on various reported criteria for lower instrumented vertebra (LIV) selection in...

Original Article

December 31, 2020

Methods and Early Clinical Results of Percutaneous Lumbar Interbody Fusion

Shu Nakamura, Fjio Ito, Zenya Ito, Motohide Shibayama

Neurospine. 2020;17(4):910-920.

Objective: Percutaneous lumbar interbody fusion (PELIF) is a procedure that includes the use of new devices, which allow minimally invasive diskectomy under the percutaneous full-endoscopic guidance and safe percutaneous insertion...

Original Article

December 31, 2020

Feasibility of the Far Lateral Suboccipital Approach to the Retroodontoid Region. How Much Bone Removal Is Truly Needed?

Gergely Bodon, Kristof Kiraly, Tamas Ruttkay, Bernhard Hirt, Heiko Koller

Neurospine. 2020;17(4):921-928.

Objective: The posterolateral extradural suboccipital approach can be used to reach the anterior epidural space and the retro-odontoid regions. The extent of necessary bone removal of the atlas vertebra (C1)...

Technical Note

December 31, 2020

Transforaminal Endoscopic Discectomy for Large, Two Level Calcified, Thoracic Disc Herniations With 5-Year Follow-up

Karlo Houra, Robert Saftic

Neurospine. 2020;17(4):954-959.

To describe technical details and benefits of transforaminal endoscopic discectomy for treatment of patients with large, dorsomedial, calcified thoracic disc herniations at 2 levels and to report on their clinical...

A Universal Craniometric Index for Establishing the Diagnosis of Basilar Invagination Jayesh Sardhara, Sanjay Behari, Suyash Singh, Arun K. Srivastava, Gaurav Chauhan, Hira Lal, Kuntal K. Das, Kamlesh Singh Bhaisora, Anant Mehrotra, Prabhakar Mishra, et al. [Accepted] Original article(Clinical) January 25, 2021 PDF	Influence of Frailty on Life Expectancy in Octogenarians After Lumbar Spine Surgery Hyun-Jun Jang, Dong-Kyu Chin, Jeong-Yoon Park, Sung-Uk Kuh, Keun-Su Kim, Yong-Eun Cho, Kyung-Hyun Kim [Accepted] Original article(Clinical) January 23, 2021 PDF
Novel Methods of Necroptosis Inhibition for Spinal Cord Injury Using Translational Research to Limit Secondary Injury and Enhance Endogenous Repair and Regeneration Brian Fiani, Athanasios Kondilis, Marisol Soula, Anthony Tao, Mohammed Ali Alvi [Accepted] Review Article January 22, 2021 PDF	Cervical Lordosis Ratio as a Novel Predictor for the Loss of Cervical Lordosis After Laminoplasty Kosei Ono, Sohei Murata, Mutsumi Matsushita, Hiroshi Murakami [Accepted] Original article(Clinical) January 22, 2021 PDF
Robot-Guided Transforaminal Versus Robot-Guided Posterior Lumbar Interbody Fusion for Lumbar Degenerative Disease Victor E. Staartjes, Bianca Battilana, Marc L. Schröder [Accepted] Original article(Clinical) December 14, 2020 PDF	Predictive Value of Heterogeneously Enhanced Magnetic Resonance Imaging Findings With Computed Tomography Evidence of Calcification for Severe Motor Deficits in Spinal Meningioma Kosei Ono, Takayoshi Shimizu, Shunsuke Fujibayashi, Bungo Otsuki, Koichi Murata, Akio Sakamoto, Shuichi Matsuda [Accepted] Original article(Clinical) December 4, 2020 PDF
Development of Neuro-Monitoring Pedicle Screw - Results of Electrical Resistance and Neurophysiologic Test in Pig Model Woo-Seok Bang, Jonghoo Park, Kyoung-Tae Kim, Dae-Chul Cho, K. Daniel Riew, Du-Hwan Kim, In-Bo Han, Seung-Jae Hyun, Do-Heum Yoon, Young-Baeg Kim [Accepted] Original article(Basic) November 18, 2020 PDF	Retro-Odontoid Pseudotumor Formation in the Context of Various Acquired and Congenital Pathologies of the Craniovertebral Junction and Surgical Techniques Brian Fiani, Rebecca Houston, Imran Siddiqi, Mohammad Arshad, Taylor Reardon, Brandon Gilliland, Cyrus Davati, Athanasios Kondilis [Accepted] Review Article November 18, 2020 PDF
Metabolic Syndrome is a Predisposing Factor for Diffuse Idiopathic Skeletal Hyperostosis Eijiro Okada, Shinichi Ishihara, Koichiro Azuma, Takehiro Michikawa, Satoshi Suzuki, Osahiko Tsuji, Satoshi Nori, Narihito Nagoshi, Mitsuru Yagi, Michiyo Takayama, et al. [Accepted] Original article(Clinical) November 17, 2020 PDF	Spontaneous Vertebral Aspergillosis, the State of art: A Systematic Literature Review Andrea Perna, Luca Ricciardi, Massimo Fantoni, Francesco Taccari, Riccardo Torelli, Domenico Alessandro Santagada, Caterina Fumo, Francesco Ciro Tamburrelli, Luca Proietti [Accepted] Review Article November 17, 2020 PDF
The Hybrid Open Muscle-Sparing Approach in Adult Spinal Deformity Patients Undergoing Lower Thoracic Fusion to the Pelvis Paul J. Park, Joe M. Lombardi, Lawrence G. Lenke [Accepted] Technical note November 17, 2020 PDF	Anterior Spinal Cord Fissuring: A Predictor of Spontaneous Resolution of Syrinx? Kartik Manoj Multani, Boyina Jagadeshwar Rajesh, Krishna Kumar, Anjani Kumar [Accepted] Case report November 17, 2020 PDF
A Prospective, Single-Blinded, Bicentric Study and Literature Review to Assess the Need of C2-Ganglion Preservation - SAVIOUR’s Criteria Suyash Singh, Arun Kumar Srivastava, Jayesh Sardhara, Kamlesh Singh Bhaisora, Kuntal Kanti Das, Anant Mehrotra, Awadhesh Kumar Jaiswal, Manas Kumar Panigrahi, Sanjay Behari [Accepted] Original article(Clinical) November 17, 2020 PDF	Effects of Body Mass Index on Peri-operative Outcomes in Patients Undergoing Anterior Cervical Discectomy and Fusion Surgery Roberto J Perez-Roman, David McCarthy, Evan M. Luther, Julian G. Lugo-Pico, Roberto Leon-Correa, Wendy Gaztanaga, Karthik Madhavan, Steven Vanni [Accepted] Original article(Clinical) November 17, 2020 PDF
Hemodynamic management of acute spinal cord injury: a literature review Young-Seok Lee, Kyoung-Tae Kim, Brian K. Kwon [Accepted] Review Article November 17, 2020 PDF