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Adult Langerhans Cell Histiocytosis of the Spine Presenting with Neurological Deficits: A Case Report.
Se Whan Ahn, Ho Gyun Ha, Hyun Woo Kim, Jung Ho Ko
Department of Neurosurgery, Konyang University School of Medicine, Daejeon, Korea. hghns@kyuh.co.kr
Abstract
The authors report a case of an unusual spinal Langerhans cell histiocytosis (LCH) in an adult presenting with neurological deficits. A 36-year-old woman presented with LCH involving the cervical spine and presenting with neurological deficit. Despite aggressive surgical intervention followed by chemotherapy and radiation therapy, recurrence at the other site occurred repeatedly and the patient eventually succumbed to acute respiratory distress syndrome. LCH is a benign disease that resolves spontaneously, but in cases with neurological deficits, aggressive surgical treatment followed by chemotherapy and radiation therapy should be considered.
Keywords: Langerhans cell histiocytosis;spine;adult


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