Treatment of Acute Spinal Cord Injury

Review

Korean J Spine 2004;1(1): 16-26.

Do Heum Yoon1,Yoon Ha2,Seung Hwan Yoon2,Eun Young Kim2,Dong Keun Hyun2,Jong Woon Park2,So Ra Park3,Sung Wook Goo1,Keung Nyun Kim1,Yong Eun Cho1 and Hyung Chun Park1,2,3

Department of Neurosurgery1, Yonsei University College of Medicine, Seoul, Korea Department of Neurosurgery1,Physiology3,Inha University College of Medicine, Inchon, Korea

급성 척수손상 환자의 치료 - 최근의 세포치료 연구 결과를 중심으로 -

윤도흠¹^,하윤²^,윤승환²^,김은영²^,현동근²^,박종운²^,박소라³^,구성욱¹^,김긍년¹^,조용은¹^,박형천¹^,²^,³

연세대학교 의과대학 신경외과학교실¹,인하대학교 의과대학 신경외과학교실²,생리학교실³

Abstract

A therapy to treat injuries to the central nervous system is, to date, a major clinical challenge. The devastating functional consequences they cause in patients have encouraged many scientists to searchm in aimal models, for a repair strategy that could, in the future, be applied to humans. To highlight the current understanding of traumatic spinal cord injury, we provide information regarding state-of-the-art care for the acute spinal cord injured model, and explore future treatments aimed at neural preservation and reconstruction. This article also reviews recent phase I clinical trials in neural and nonneural cell transplantation, stressing that the transition from basic science to clinical applications.

Keywords: Spinal cord injury(SCI), Transplantation