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Percutaneous Vertebroplasty for the Treatment of Osteoporotic Vertebral Compression Fractures: Recent 2-year Experience
Sang-Dae Kim, M.D.1, Jung-Yul Park, M.D.1, Se-Hoon Kim, M.D.1, Jung-Keun Suh, M.D.1,Tae-Soo Lee, Ph.D.2 and Soo-Won Chae, Ph.D.3
Department of Neurosurgery, College of Medicine, Korea University, Seoul, Korea1,Department of Mechanical Engineering, So-Gang University, Seoul, Korea2,Department of Mechanical Engineering, Korea University, Seoul, Korea3
골다공성 척추 압박골절 환자에 대한 경피적 척추체성형술 : 최근 2년간 경험
김상대1·박정율1·김세훈1·서중근1·이태수2·채수원3
고려대학교 의과대학 신경외과학교실1, 서강대학교 기계공학과2, 고려대학교 기계공학과3
Abstract
Objective
To describe the therapeutic outcome of percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures(OVCF) in recent years with review of literature.
Methods
The authors have retrospectively reviewed a consecutive group of patients who underwent percutaneous verteb- roplasty in our institution between May 2000 and October 2002. The procedures were performed with Jamshidi needle via transpedicular approach followed by injection of polymethyl- methacrylate(PMMA) into the involved vertebral bodies. Prolo's economic and functional rating scale was used for therapeutic outcome assessments.
Results
There were 91 patients(69 female, 22 male) with OVCF, with involvement of 147 vertebral bodies. The mean age was 72 years. The average BMD t-score was -3.78, indicative of severe osteoporosis. Minimal follow-up period was three months. And among these patients, 82.5% of patients were maintained over good condition. Extrusion of PMMA cement beyond the confines of the vertebral body was obseved in 13 cases(8.8%). Although most of them improved with conservative treatments without morbidities, two developed serious complications, one being pulmonary embolism and the other paraparesis.
Conclusion
Percutaneous vertebroplasty is one of the effective minimal invasive treatment modalities in OVCF. However, proper biomechanical studies supporting these procedures are not fully evidenced. Serious complications, although rare, should be prevented with the aid of improved techniques and newer biocompatible materials along with better understanding of biodynamic and biomechanical impact on normal and already compromised vertebraes.
Keywords: Osteoporosis, Compression, Fracture, Vertebroplasty, Polymethylmethacrylate, Biomechanics


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