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Vertebroplasty for Osteoporotic Compression Fracture: Biomechanics and Clinical Applications
Sang-Dae Kim, M.D. and Jung-Yul Park, M.D.
Department of Neurosurgery, College of Medicine, Korea University, Korea
Abstract
Percutaneous vertebroplasty(PV) has been rapidly accepted since its first introduction in clinical practice as a very effective and efficient means to simultaneously minimize the pain and stabi1ize the fractured vertebral bodies. It has steadily shown an excellent pain relief and functinal restroartion with a acceptable complication rates. However, it also has been associated with substantial number of complications, few with disastrous clinical situations. Thus, every effort should be practiced to prevent or to minimize such unwanted results. Despite its popularity, its practice has been usually anecdotal, without proper standardized biodynamic and biomechanical studies, and retrospective. Also, results from longer follow-up studies are not sufficient and comparison with natural courses also are not greatly appreciated. Recently, many investigations have conducted for its action mechanism for pain reduction, biodynamic interaction with adjacent vertebras, other alternative materials for injection, optimal volume and route of injection, and ideal targeted location of injectate. Such efforts will elucidate and answer questions near in future for unsolved and uncleared issues currently present. Objective of this paper is to review the reported works of vertebropalsy in basic and clinical aspects of vertebroplasty with regards to its applications in the past, present and future. The authors hope these up-to-dated knowledges will help to enhance and heighten for better clinical outcome and to provide more comforts to the patients with these disabling conditions.
Keywords: OsteoporosisㆍCompression fractureㆍVertebroplastyㆍBiodynamcisㆍCementㆍPolymethylmethacrylate(PMMA)


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