Warning: mkdir(): Permission denied in /home/virtual/lib/view_data.php on line 81 Warning: fopen(/home/virtual/e-kjs/journal/upload/ip_log/ip_log_2024-04.txt): failed to open stream: No such file or directory in /home/virtual/lib/view_data.php on line 83 Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 84 Significance of Changes in Erythrocyte Sedimentation Rate and C-Reactive Protein Counts in Pyogenic Spondylitis Treatment
Korean J Spine Search

CLOSE


8
Significance of Changes in Erythrocyte Sedimentation Rate and C-Reactive Protein Counts in Pyogenic Spondylitis Treatment
Ki-Hyun Jeon, M.D., Jin-Young Youm, M.D., Seung-Won Choi, M.D., Hyun-Song Koh, M.D., Shi-Hun Song, M.D. and Youn Kim, M.D.
Department of Neurosurgery, College of Medicine, Chungnam National University, Daejeon, Korea
화농성 척추 감염 치료에 따른 적혈구 침강속도, C-반응성 단백질 수치 변화의 중요성
전기현, 염진영, 최승원, 고현송, 송시헌, 김 윤
충남대학교 의과대학 신경외과학교실
Abstract
Objective
The changes of Erythrocyte Sedimentation Rate(ESR) and C-Reactive Protein(CRP) counts in pyogenic spondylitis patients analyzed to determine the treatment modality, effect and the duration of antibiotics medication.
Methods
ESR and CRP counts were examined on 15 pyogenic spondylitis patients from the beginning of hospitalization to normalization, twice per week between January 2001 and December 2003.
Results
In all of the 15 pyogenic spondylitis cases, the average ESR(63.8mm/hr) and CRP(7.2mg/dL) counts had risen before the treatment. The operated group is more severe infectious state than non-operated group. The average ESR reduction time down to the 2/3s of the initial level was 2.4 and 1.0 weeks for the operated group and non-operated group respectively. The average CRP counts reduction time was 1.0 and 1.3 weeks correspondingly. The average ESR normalization time was 8.0 and 6.9 weeks for the operated group and non-operated group respectively. The average normalization time of CRP counts was observed as 6.4 and 5.6 weeks correspondingly.
Conclusion
Regular examination and follow up ESR and CRP counts are essential in the diagonosis of pyogenic spinal infection and the evaluation of the treatment effect. This study implies that the regular examination of CRP count is necessary for proper usage of antibiotics in the early stage of treatment, and ESR examination is more useful to determine when to terminate antibiotics treatment in the latter stage of treatment.
Keywords: Erythrocyte sedimentation rate, C-Reactive protein, Pyogenic spondylitis


Editorial Office
CHA University, CHA School of Medicine Bundang Medical Center
59 Yatap-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 13496, Korea
Tel: +82-31-780-1924  Fax: +82-31-780-5269  E-mail: support@e-neurospine.org
The Korean Spinal Neurosurgery Society
#407, Dong-A Villate 2nd Town, 350 Seocho-daero, Seocho-gu, Seoul 06631, Korea
Tel: +82-2-585-5455  Fax: +82-2-2-523-6812  E-mail: ksns1987@gmail.com
Business License No.: 209-82-62443

Copyright © The Korean Spinal Neurosurgery Society.

Developed in M2PI

Close layer
prev next