Korean J Spine Search


Clinical Analysis of Newly Developed Vertebral Fractures after Percutaneous Vertebroplasty in Osteoporotic Thoracolumbar Vertebral Compression Fractures
Jin Gyu Park, M.D., Gyeung Sik Ryu, M.D., Chun Guen Park, M.D.
Department of Neurosurgery, Kang Nam St. Mary's Hospital, The Catholic University of Korea
골다공증성 흉요추 압박 골절 환자에서 경피적 척추 성형술 후 발생하는 신생 척추 골절의 임상적 의의
가톨릭대학교 의과대학 강남성모병원 신경외과학교실
Objective: Recently, many clinicians have analyzed the therapeutic effects of polymethylmethacrylate percutaneous vertebroplasty(PMMA-PV) for the treatment of osteoporotic vertebral fractures. However, it has been suggested that PMMA-PV enhances new vertebral fractures in the level adjacent to the previously treated site. The authors verified the clinical relationship between PMMA-PV and newly developed vertebral fractures following this procedure.
Methods: Among 215 patients treated with PMMA-PV, 32 cases(14.9%) experienced newly developed thoraco-lumbar vertebral fractures during the follow-up period(8.9±5.9 months on the average). There were 2 male and 30 female patients. The mean age was 71.3 years. The numbers of previously treated and newly developed vertebrae were 87 and 53, res- pectively. The average amount of injected PMMA during the first operation was 4.41±1.62cc. The average T-score of bone mineral densitometey(BMD) was -2.91±1.26.
Results: Among 53 newly fractured vertebrae, 23(43.4%) were located adjacently to previously treated vertebrae. In statistical analysis between the locations of new fractures and the amount of previously injected PMMA, T-score of BMD did not show any significant relationship.
Conclusion: Our data revealed that new vertebral fractures following PMMA-PV have a tendency to occur at the adja- cent level to be treated previously. The amount of injected PMMA and the T-score of BMD were not related with the location of new fractures.
Keywords: OsteoporosisㆍVertebral fractureㆍPercutaneous vertebropalstyㆍPolymethylmethacrylate

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