Dear Colleagues,

Spinal vertebrae are unique bony skeleton composing of 70% cancellous bone and 30% cortical bone, which has the dynamic nature of “bone remodeling” involving the co-ordinated actions of osteoblasts, osteoclasts and osteocytes.

For the good surgical outcome of the elderly patient with spine disease, it is very important to achieve a thorough understanding the knowledge of Bone Biology and Osteoporosis, which can help to select an appropriate drugs for the treatment of osteoporosis, and surgical treatment of aging spine.

In this special issue of “Bone Biology and Osteoporosis”, Neurospine invite internationally renowned people in the field of Bone Biology and spine surgery, which will cover the basic knowledge of bone biology, various drugs for the treatment of osteoporosis, as well as the surgical treatment of osteoporotic spine.

Dae-Chul Cho (Kyungpook National Univ. Hospital, Korea)	Alexander Ropper (Baylor College of Medicine, USA)	Jau-Ching Wu (Taipei Veterans General Hospital, Taiwan)

Masahiro Kawanishi (Takeda General Hospital, Japan)	Toshiuki Takahashi (Fujeda Heisei Memorial Hospital, Japan)	Biao Wang (Honghui Hospital, Xi'an Jiaotong Univ., China)

Ho Yeon Chung (Kyung Hee Univ. Hostpital, Korea)	Sung Bae Park (Seoul National Univ. Hospital, Korea)	Man Kyu Choi (Kyung Hee Univ. Hospital, Korea)	Ho Jin Lee (Catholic Univ. St. Vincent Hospital, Korea)

Sung Hyun Noh (Ajou Univ. Hospital, Korea)