Solitary Hemangioblastoma at the Filum Terminale: A Case Report and Review of Literature.

Lee,  Jung Hoon; Kim,  Jin Uk; Paeng,  Sung Suk; Jang,  Jee Soo; Lee,  Sang Ho

doi:2011.8.2.125

Case Report

Korean J Spine 2011;8(2): 125-128.

DOI: https://doi.org/10.14245/kjs.2011.8.2.125

Solitary Hemangioblastoma at the Filum Terminale: A Case Report and Review of Literature.

Jung Hoon Lee, Jin Uk Kim, Sung Suk Paeng, Jee Soo Jang, Sang Ho Lee

¹Department of Neurosurgery, Seoul Wooridul Hospital, Seoul, Korea.
²Department of Orthopaedic Surgery, Seoul Wooridul Hospital, Seoul, Korea. ultralex@wooridul.co.kr
³Department of Pathology, Seoul Wooridul Hospital, Seoul, Korea.

Abstract

Spinal hemangioblastomas at the filum terminale are rare. Only a few reports present immunohistopathological features of spinal hemangioblastomas. A 55-year-old woman presented with sustained low back pain and intermittent numbness in both lower extremities. She already had a decompressive surgery for a left L5-S1 extraforaminal lesion 7 months ago. Her incidental mass lesion had been slightly enlarged for 7 months and concordant symptoms had also been prolonged. Her tumor was removed en bloc with a unilateral hemilaminotomy and bilateral decompression technique. The patient's symptoms improved immediately after the surgery. In immunohistochemical stains, the stromal cells were positive for inhibin-alpha, neuron specific enolase (NSE), and the endothelial cells were positive for CD31, CD34, and factor VIII related antigen in confirming the diagnosis of hemangioblastoma. We report a rare case of intradural extramedullary spinal hemangioblastoma at the filum terminale. Complete en bloc resection was achieved with no morbidity. The immunohistopathological staining include inhibin-alpha confirmed an accurate diagnosis of the hemangioblastoma distinguishing from other vascular tumors.

Keywords: Spinal hemangioblastoma;Filum terminale;Immunohistopathological stain