The authors report a case of metastatic malignant melanoma to the spine. A 30-year-old male patient was presented with severe low back pain and both legs radiculopathy with intermittent neurogenic claudication. Magnetic resonance imaging study showed a pathologic fracture of L4 vertebral body and a mass lesion compressing the dural sac anteriorly. Also it showed a pedicle lesion of L2. He underwent a L4 vertebrectomy and partial resection of epidural mass with anterior retroperitoneal approach. For stability, total laminectomy and posterior spinal fusion was performed. Histologic findings revealed a malignant melanoma.