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Neurospine provides spine clinicians and researchers with peer-reviewed articles on basic and clinical investigation of spine and spinal cord to enhance patient management, education, clinical or experimental research, and professionalism.
The journal will consider submissions in areas on craniocervical to lumbosacral spine including the followings: neuroscience and pain research, bone and mineral research, disc and joint research, bio and industrial technology, pathophysiology, risk factors, symptomatology, imaging, treatment, rehabilitation of spine, spinal cord and peripheral nerve diseases.

Review Article

March 31, 2020


Gene Therapy Approach for Intervertebral Disc Degeneration: An Update
Yoshiki Takeoka, Takashi Yurube, Kotaro Nishida
Neurospine. 2020;17(1):3-14.

Review Article

March 31, 2020


Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Review
Tibo Nico Emmie Volleman, Jordy Schol, Kosuke Morita, Daisuke Sakai, Masahiko Watanabe
Neurospine. 2020;17(1):19-35.

Original Article

March 31, 2020


Correlation of Early Outcomes and Intradiscal Interleukin-6 Expression in Lumbar Fusion Patients
John D. Koerner, Dessislava Z. Markova, Greg D. Schroeder, Christopher L. Antonacci, Joseph Mendelis, Alexander R. Vaccaro, D. Greg Anderson, Chris K. Kepler
Neurospine. 2020;17(1):36-41.

Original Article

March 31, 2020


Direct and Intervertebral Disc-Mediated Sensitization of Dorsal Root Ganglion Neurons by Hypoxia and Low pH
Junxuan Ma, Despina Stefanoska, Sibylle Grad, Mauro Alini, Marianna Peroglio
Neurospine. 2020;17(1):42-59.

Original Article

March 31, 2020


Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells
Nam Vo, Brandon Couch, Joon Lee, Gwendolyn Sowa, James Kang, Studer Rebecca
Neurospine. 2020;17(1):60-68.

Original Article

March 31, 2020


Rabbit Annulus Fibrosus Cells Express Neuropeptide Y, Which Is Influenced by Mechanical and Inflammatory Stress
Malcolm E. Dombrowski, Adam S. Olsen, Nicholas Vaudreuil, Brandon K. Couch, Qing Dong, Michelle Tucci, Joon Y. Lee, Nam V. Vo, Gwendolyn Sowa
Neurospine. 2020;17(1):69-76.

Original Article

March 31, 2020


Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype
Rahel D. May, Daniela A. Frauchiger, Christoph E. Albers, Willy Hofstetter, Benjamin Gantenbein
Neurospine. 2020;17(1):77-87.

Review Article

March 31, 2020


Robotic Spine Surgery and Augmented Reality Systems: A State of the Art
Gianluca Vadalà, Sergio De Salvatore, Luca Ambrosio, Fabrizio Russo, Rocco Papalia, Vincenzo Denaro
Neurospine. 2020;17(1):88-100.

Review Article

November 4, 2019


Biomaterials in Spinal Implants: A Review
Andrew Warburton, Steven J. Girdler, Christopher M. Mikhail, Amy Ahn, Samuel K. Cho
Neurospine. 2020;17(1):101-110.

Original Article

March 31, 2020


Telerobotic Spinal Surgery Based on 5G Network: The First 12 Cases
Wei Tian, Mingxing Fan, Cheng Zeng, Yajun Liu, Da He, Qi Zhang
Neurospine. 2020;17(1):114-120.

Original Article

March 31, 2020


Polyetheretherketone Versus Titanium Cages for Posterior Lumbar Interbody Fusion: Meta-Analysis and Review of the Literature
Elie Massaad, Nida Fatima, Ali Kiapour, Muhamed Hadzipasic, Ganesh M. Shankar, John H. Shin
Neurospine. 2020;17(1):125-135.

Original Article

April 12, 2019


Rigid-Plating and Cortico-Cancellous Allograft Are Effective for 3-Level Anterior Cervical Discectomy and Fusion: Radiographic and Clinical Outcomes
Philip K. Louie, Andrew C. Sexton, Danel D. Bohl, Ehsan Tabaraee, Steven M. Presciutti, Benjamin C. Mayo, Justin C. Paul, Comron Saifi, Howard S. An
Neurospine. 2020;17(1):146-155.

Original Article

July 5, 2019


Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
Chi Hyung Lee, Dong Wuk Son, Su Hun Lee, Jun Seok Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
Neurospine. 2020;17(1):156-163.

Original Article

July 9, 2019


Degenerative Cervical Myelopathy: A 7-Letter Coding System That Supports Decision-Making for the Surgical Approach
Luca Papavero, Gregor Schmeiser, Ralph Kothe, Bronek Boszczyk, Oliver Heese, Yoshiharu Kawaguchi, Anna MacDowall, Claes Olerud, Nikolaos Paidakakos, Anastasios Panagiotou, et al.
Neurospine. 2020;17(1):164-171.

Original Article

March 31, 2020


Effect of the Presence and Type of Plate Augmentation on Postoperative Dysphagia Among Adult Patients Undergoing Elective Anterior Cervical Discectomy and Fusion for Spondylosis: A Randomized Trial
Tom J. O’Donohoe, Lisa Mililli, Alison Magee, Christopher Thien, Yi Yuen Wang
Neurospine. 2020;17(1):174-183.

Original Article

February 5, 2020


Evaluation of Postoperative Mental Health Outcomes in Patients Based on Patient-Reported Outcome Measurement Information System Physical Function Following Anterior Cervical Discectomy and Fusion
Joon S. Yoo, Nathaniel W. Jenkins, James M. Parrish, Thomas S. Brundage, Nadia M. Hrynewycz, Franchesca A. Mogilevsky, Kern Singh
Neurospine. 2020;17(1):184-189.

Original Article

March 31, 2020


The Impact of Modic Changes on Preoperative Symptoms and Clinical Outcomes in Anterior Cervical Discectomy and Fusion Patients
James D. Baker, Garrett K. Harada, Youping Tao, Philip K. Louie, Bryce A. Basques, Fabio Galbusera, Frank Niemeyer, Hans-Joachim Wilke, Howard S. An, Dino Samartzis
Neurospine. 2020;17(1):190-203.

Original Article

March 31, 2020


Timing of Surgery in Tubular Microdiscectomy for Lumbar Disc Herniation and Its Effect on Functional Impairment Outcomes
Alessandro Siccoli, Marlies P. de Wispelaere, Marc L. Schröder, Victor E. Staartjes
Neurospine. 2020;17(1):204-212.

Original Article

March 31, 2020


The Influence of Mechanic Factors in Disc Degeneration Disease as a Determinant for Surgical Indication
Gulden Demirci Otluoğlu, Deniz Konya, Zafer Orkun Toktas
Neurospine. 2020;17(1):215-220.

Original Article

March 31, 2020


Image-Based Markers Predict Dynamic Instability in Lumbar Degenerative Spondylolisthesis
William Slikker III, Alejandro A. Espinoza Orías, Grant D. Shifflett, Joe Y.B. Lee, Krzysztof Siemionow, Sapan Gandhi, Louis Fogg, Dino Samartzis, Nozomu Inoue, Howard S. An
Neurospine. 2020;17(1):221-227.

Original Article

March 31, 2020


Less Opioid Consumption With Enhanced Recovery After Surgery Transforaminal Lumbar Interbody Fusion (TLIF): A Comparison to Standard Minimally-Invasive TLIF
Hsuan-Kan Chang, Meng Huang, Jau-Ching Wu, Wen-Cheng Huang, Michael Y. Wang
Neurospine. 2020;17(1):228-236.

Original Article

July 24, 2019


Use of Opioids and Other Analgesics Before and After Primary Surgery for Adult Spinal Deformity: A 10-Year Nationwide Study
Frederik Taylor Pitter, Matt Sikora, Martin Lindberg-Larsen, Alma Becic Pedersen, Benny Dahl, Martin Gehrchen
Neurospine. 2020;17(1):237-245.

Original Article

March 31, 2020


Opioids and Spinal Cord Stimulators: Pre- and Postoperative Opioid Use Patterns and Predictors of Prolonged Postoperative Opioid Use
Lawal Labaran, Jomar N.A. Aryee, Joshua Bell, Nikhil Jain, Varun Puvanesarajah, Micheal Raad, Amit Jain, Jonathan Carmouche, Hamid Hassanzadeh
Neurospine. 2020;17(1):246-253.

Original Article

February 1, 2020


Comparison of the Safety and Effectiveness of Percutaneous Endoscopic Lumbar Discectomy for Treating Lumbar Disc Herniation Under Epidural Anesthesia and General Anesthesia
Zhiqiang Ren, Shenghua He, Jiao Li, Yeguang Wang, Juyi Lai, Zhitao Sun, Hualong Feng, Jian Wang
Neurospine. 2020;17(1):254-259.

Original Article

February 5, 2020


The Navigated Oblique Lumbar Interbody Fusion: Accuracy Rate, Effect on Surgical Time, and Complications
Zhuo Xi, Dean Chou, Praveen V. Mummaneni, Shane Burch
Neurospine. 2020;17(1):260-267.

Original Article

January 26, 2020


Lower Extremity Motor Deficits Are Underappreciated in Patient-Reported Outcome Measures: Added Value of Objective Outcome Measures
Martin Nikolaus Stienen, Nicolai Maldaner, Marketa Sosnova, Holger Joswig, Marco Vincenzo Corniola, Luca Regli, Gerhard Hildebrandt, Karl Schaller, Oliver Pascal Gautschi
Neurospine. 2020;17(1):270-280.

Original Article

October 15, 2019


A New Shielding Curtain for Protection of Intraoperative Radiation During Minimally Invasive Spine Surgery
Se Hoon Park, Myeong Jin Ko, Yong Sook Park, Jaehan Yun, Hongsik Byun, Seung Won Park
Neurospine. 2020;17(1):288-293.

Original Article

July 11, 2019


Re-examining the Spectrum of Lumbosacral Transitional Dysmorphisms: Quantifying Joint Asymmetries and Evaluating the Anatomy of Screw Fixation Corridors
Niladri Kumar Mahato
Neurospine. 2020;17(1):294-303.

Original Article

February 1, 2020


Oxford Cobbometer Versus Computer Assisted-Software for Measurement of Cobb Angle in Adolescent Idiopathic Scoliosis
Tarek Elfiky, Nirmal Patil, Mohamed Shawky, Ahmed Siam, Raafat Ragab, Yasser Allam
Neurospine. 2020;17(1):304-311.

Bench to Bed (B2B) Project; Intervertebral Disc Degeneration in Collaboration With Biospine
Joo Han Kim
Neurospine. 2020;17(1):1-2.

Introduction

March 31, 2020

Gene Therapy Approach for Intervertebral Disc Degeneration: An Update
Yoshiki Takeoka, Takashi Yurube, Kotaro Nishida
Neurospine. 2020;17(1):3-14.

Review Article

March 31, 2020

Commentary on “Gene Therapy Approach for Intervertebral Disc Degeneration: An Update”
James D. Kang
Neurospine. 2020;17(1):15-16.

Editorial

March 31, 2020

Moving Forward: Gene Therapy for Intervertebral Disc Degeneration
In-Bo Han
Neurospine. 2020;17(1):17-18.

Editorial

March 31, 2020

Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Review
Tibo Nico Emmie Volleman, Jordy Schol, Kosuke Morita, Daisuke Sakai, Masahiko Watanabe
Neurospine. 2020;17(1):19-35.

Review Article

March 31, 2020

Correlation of Early Outcomes and Intradiscal Interleukin-6 Expression in Lumbar Fusion Patients
John D. Koerner, Dessislava Z. Markova, Greg D. Schroeder, Christopher L. Antonacci, Joseph Mendelis, Alexander R. Vaccaro, D. Greg Anderson, Chris K. Kepler
Neurospine. 2020;17(1):36-41.

Original Article

March 31, 2020

Direct and Intervertebral Disc-Mediated Sensitization of Dorsal Root Ganglion Neurons by Hypoxia and Low pH
Junxuan Ma, Despina Stefanoska, Sibylle Grad, Mauro Alini, Marianna Peroglio
Neurospine. 2020;17(1):42-59.

Original Article

March 31, 2020

Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells
Nam Vo, Brandon Couch, Joon Lee, Gwendolyn Sowa, James Kang, Studer Rebecca
Neurospine. 2020;17(1):60-68.

Original Article

March 31, 2020

Rabbit Annulus Fibrosus Cells Express Neuropeptide Y, Which Is Influenced by Mechanical and Inflammatory Stress
Malcolm E. Dombrowski, Adam S. Olsen, Nicholas Vaudreuil, Brandon K. Couch, Qing Dong, Michelle Tucci, Joon Y. Lee, Nam V. Vo, Gwendolyn Sowa
Neurospine. 2020;17(1):69-76.

Original Article

March 31, 2020

Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype
Rahel D. May, Daniela A. Frauchiger, Christoph E. Albers, Willy Hofstetter, Benjamin Gantenbein
Neurospine. 2020;17(1):77-87.

Original Article

March 31, 2020

Robotic Spine Surgery and Augmented Reality Systems: A State of the Art
Gianluca Vadalà, Sergio De Salvatore, Luca Ambrosio, Fabrizio Russo, Rocco Papalia, Vincenzo Denaro
Neurospine. 2020;17(1):88-100.

Review Article

March 31, 2020

Biomaterials in Spinal Implants: A Review
Andrew Warburton, Steven J. Girdler, Christopher M. Mikhail, Amy Ahn, Samuel K. Cho
Neurospine. 2020;17(1):101-110.

Review Article

November 4, 2019

Commentary on “Biomaterials in Spinal Implants: A Review”
Hans-Joerg Meisel, Neha Agarwal
Neurospine. 2020;17(1):111-113.

Editorial

March 31, 2020

Telerobotic Spinal Surgery Based on 5G Network: The First 12 Cases
Wei Tian, Mingxing Fan, Cheng Zeng, Yajun Liu, Da He, Qi Zhang
Neurospine. 2020;17(1):114-120.

Original Article

March 31, 2020

Remote Robotic Spine Surgery
John R. Adler
Neurospine. 2020;17(1):121-122.

Editorial

March 31, 2020

The Future of Spine Surgery in the Fourth Industrial Revolution: Telerobotic Spine Surgery
Yong Eun Cho
Neurospine. 2020;17(1):123-124.

Editorial

March 31, 2020

Polyetheretherketone Versus Titanium Cages for Posterior Lumbar Interbody Fusion: Meta-Analysis and Review of the Literature
Elie Massaad, Nida Fatima, Ali Kiapour, Muhamed Hadzipasic, Ganesh M. Shankar, John H. Shin
Neurospine. 2020;17(1):125-135.Correction in: Neurospine 2020;17(2):473

Original Article

March 31, 2020

Smartphone-Based Self-Assessment of Objective Functional Impairment (6-Minute Walking Test) in Patients Undergoing Epidural Steroid Injection
Anna Maria Zeitlberger, Marketa Sosnova, Michal Ziga, Valentin Steinsiepe, Oliver P. Gautschi, Martin N. Stienen, Nicolai Maldaner
Neurospine. 2020;17(1):136-142.

Case Report

March 31, 2020

The Advent of Smartphone Applications in Spine Surgery: Bringing the Field to the 21st Century
Don Young Park
Neurospine. 2020;17(1):143-145.

Editorial

March 31, 2020

Rigid-Plating and Cortico-Cancellous Allograft Are Effective for 3-Level Anterior Cervical Discectomy and Fusion: Radiographic and Clinical Outcomes
Philip K. Louie, Andrew C. Sexton, Danel D. Bohl, Ehsan Tabaraee, Steven M. Presciutti, Benjamin C. Mayo, Justin C. Paul, Comron Saifi, Howard S. An
Neurospine. 2020;17(1):146-155.

Original Article

April 12, 2019

Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65–74 Years) and Middle-Old Patients (Over 75 Years)
Chi Hyung Lee, Dong Wuk Son, Su Hun Lee, Jun Seok Lee, Soon Ki Sung, Sang Weon Lee, Geun Sung Song
Neurospine. 2020;17(1):156-163.

Original Article

July 5, 2019

Degenerative Cervical Myelopathy: A 7-Letter Coding System That Supports Decision-Making for the Surgical Approach
Luca Papavero, Gregor Schmeiser, Ralph Kothe, Bronek Boszczyk, Oliver Heese, Yoshiharu Kawaguchi, Anna MacDowall, Claes Olerud, Nikolaos Paidakakos, Anastasios Panagiotou, et al.
Neurospine. 2020;17(1):164-171.

Original Article

July 9, 2019

Commentary on “Degenerative Cervical Myelopathy: A 7-Letter Coding System That Supports Decision-Making for the Surgical Approach”
Oliver Hausmann
Neurospine. 2020;17(1):172-173.

Editorial

March 31, 2020

Effect of the Presence and Type of Plate Augmentation on Postoperative Dysphagia Among Adult Patients Undergoing Elective Anterior Cervical Discectomy and Fusion for Spondylosis: A Randomized Trial
Tom J. O’Donohoe, Lisa Mililli, Alison Magee, Christopher Thien, Yi Yuen Wang
Neurospine. 2020;17(1):174-183.

Original Article

March 31, 2020

Evaluation of Postoperative Mental Health Outcomes in Patients Based on Patient-Reported Outcome Measurement Information System Physical Function Following Anterior Cervical Discectomy and Fusion
Joon S. Yoo, Nathaniel W. Jenkins, James M. Parrish, Thomas S. Brundage, Nadia M. Hrynewycz, Franchesca A. Mogilevsky, Kern Singh
Neurospine. 2020;17(1):184-189.

Original Article

February 5, 2020

The Impact of Modic Changes on Preoperative Symptoms and Clinical Outcomes in Anterior Cervical Discectomy and Fusion Patients
James D. Baker, Garrett K. Harada, Youping Tao, Philip K. Louie, Bryce A. Basques, Fabio Galbusera, Frank Niemeyer, Hans-Joachim Wilke, Howard S. An, Dino Samartzis
Neurospine. 2020;17(1):190-203.

Original Article

March 31, 2020

Timing of Surgery in Tubular Microdiscectomy for Lumbar Disc Herniation and Its Effect on Functional Impairment Outcomes
Alessandro Siccoli, Marlies P. de Wispelaere, Marc L. Schröder, Victor E. Staartjes
Neurospine. 2020;17(1):204-212.

Original Article

March 31, 2020

Surgical Timing in Lumbar Disc Herniation Surgery
Chi Heon Kim
Neurospine. 2020;17(1):213-214.

Editorial

March 31, 2020

The Influence of Mechanic Factors in Disc Degeneration Disease as a Determinant for Surgical Indication
Gulden Demirci Otluoğlu, Deniz Konya, Zafer Orkun Toktas
Neurospine. 2020;17(1):215-220.

Original Article

March 31, 2020

Image-Based Markers Predict Dynamic Instability in Lumbar Degenerative Spondylolisthesis
William Slikker III, Alejandro A. Espinoza Orías, Grant D. Shifflett, Joe Y.B. Lee, Krzysztof Siemionow, Sapan Gandhi, Louis Fogg, Dino Samartzis, Nozomu Inoue, Howard S. An
Neurospine. 2020;17(1):221-227.

Original Article

March 31, 2020

Less Opioid Consumption With Enhanced Recovery After Surgery Transforaminal Lumbar Interbody Fusion (TLIF): A Comparison to Standard Minimally-Invasive TLIF
Hsuan-Kan Chang, Meng Huang, Jau-Ching Wu, Wen-Cheng Huang, Michael Y. Wang
Neurospine. 2020;17(1):228-236.

Original Article

March 31, 2020

Use of Opioids and Other Analgesics Before and After Primary Surgery for Adult Spinal Deformity: A 10-Year Nationwide Study
Frederik Taylor Pitter, Matt Sikora, Martin Lindberg-Larsen, Alma Becic Pedersen, Benny Dahl, Martin Gehrchen
Neurospine. 2020;17(1):237-245.

Original Article

July 24, 2019

Opioids and Spinal Cord Stimulators: Pre- and Postoperative Opioid Use Patterns and Predictors of Prolonged Postoperative Opioid Use
Lawal Labaran, Jomar N.A. Aryee, Joshua Bell, Nikhil Jain, Varun Puvanesarajah, Micheal Raad, Amit Jain, Jonathan Carmouche, Hamid Hassanzadeh
Neurospine. 2020;17(1):246-253.

Original Article

March 31, 2020

Comparison of the Safety and Effectiveness of Percutaneous Endoscopic Lumbar Discectomy for Treating Lumbar Disc Herniation Under Epidural Anesthesia and General Anesthesia
Zhiqiang Ren, Shenghua He, Jiao Li, Yeguang Wang, Juyi Lai, Zhitao Sun, Hualong Feng, Jian Wang
Neurospine. 2020;17(1):254-259.

Original Article

February 1, 2020

The Navigated Oblique Lumbar Interbody Fusion: Accuracy Rate, Effect on Surgical Time, and Complications
Zhuo Xi, Dean Chou, Praveen V. Mummaneni, Shane Burch
Neurospine. 2020;17(1):260-267.

Original Article

February 5, 2020

Impact of Spinal Navigation on the Oblique Lumbar Interbody Fusion
Paul Park
Neurospine. 2020;17(1):268-269.

Editorial

March 31, 2020

Lower Extremity Motor Deficits Are Underappreciated in Patient-Reported Outcome Measures: Added Value of Objective Outcome Measures
Martin Nikolaus Stienen, Nicolai Maldaner, Marketa Sosnova, Holger Joswig, Marco Vincenzo Corniola, Luca Regli, Gerhard Hildebrandt, Karl Schaller, Oliver Pascal Gautschi
Neurospine. 2020;17(1):270-280.

Original Article

January 26, 2020

The Bull or the Horn – What Are Outcomes Data?
James Harrop
Neurospine. 2020;17(1):281-282.

Editorial

March 31, 2020

Does the Rise of Objective Measure of Functional Impairment Mean the Fall of PROMs?
Satoshi Yamaguchi
Neurospine. 2020;17(1):283-284.

Editorial

March 31, 2020

A New Possible Standard in Evaluating Lower Extremity Motor Weakness
James M. Parrish, Nathaniel W. Jenkins, Kern Singh
Neurospine. 2020;17(1):285-287.

Editorial

March 31, 2020

A New Shielding Curtain for Protection of Intraoperative Radiation During Minimally Invasive Spine Surgery
Se Hoon Park, Myeong Jin Ko, Yong Sook Park, Jaehan Yun, Hongsik Byun, Seung Won Park
Neurospine. 2020;17(1):288-293.

Original Article

October 15, 2019

Re-examining the Spectrum of Lumbosacral Transitional Dysmorphisms: Quantifying Joint Asymmetries and Evaluating the Anatomy of Screw Fixation Corridors
Niladri Kumar Mahato
Neurospine. 2020;17(1):294-303.

Original Article

July 11, 2019

Oxford Cobbometer Versus Computer Assisted-Software for Measurement of Cobb Angle in Adolescent Idiopathic Scoliosis
Tarek Elfiky, Nirmal Patil, Mohamed Shawky, Ahmed Siam, Raafat Ragab, Yasser Allam
Neurospine. 2020;17(1):304-311.

Original Article

February 1, 2020


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